Identification of three immunodominant regions on leukotoxin protein of Fusobacterium necrophorum

Veterinary Research Communications

Volumn 33, Issue 7, 2009, Pages 749-755

  Sun, D B ^a   Wu, R ^a   Li, G L ^a   Zheng, J S ^a   Liu, X P ^a   Lin, Y C ^a   Guo, D H ^a  

^a HEILONGJIANG AUGUST FIRST LAND RECLAMATION UNIVERSITY   (China)

Author keywords

Footrot; Fusobacterium necrophorum; Immunodominant; Leukotoxin

Indexed keywords

BACTERIAL VACCINE; LEUKOTOXIN; RECOMBINANT PROTEIN; RECOMBINANT PROTEIN PL1; RECOMBINANT PROTEIN PL2; RECOMBINANT PROTEIN PL3; RECOMBINANT PROTEIN PL4; RECOMBINANT PROTEIN PL5; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG ANTIGENICITY; DRUG EFFICACY; DRUG SCREENING; ESCHERICHIA COLI; FOOT ROT; FUSOBACTERIUM NECROPHORUM; GENE EXPRESSION; GENE VECTOR; HISTOPATHOLOGY; INFECTION PREVENTION; LEMIERRE SYNDROME; LIVER INJURY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEIN PURIFICATION; VACCINATION; VACCINE PRODUCTION;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CYTOTOXINS; DNA PRIMERS; ESCHERICHIA COLI; EXOTOXINS; FOOT ROT; FUSOBACTERIUM; GENETIC VECTORS; HEMOLYSIN PROTEINS; IMMUNOSUPPRESSIVE AGENTS; RECOMBINANT PROTEINS; RUMINANTS; VIRULENCE;

ESCHERICHIA COLI; FUSOBACTERIUM NECROPHORUM; MUS;

EID: 70349255912     PISSN: 01657380     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11259-009-9223-6     Document Type: Article

References (13)

1. Abe, P., Lennard, E., Holland, J., 1976. Fusobacterium necrophorum infection in mice as a model for the study of liver abscess formation and induction of immunity, Infection and Immunity, 13, 1473-1478.
2. Conion, P., Hepper, K., Teresa, G., 1977. Evaluation of experimentally induced Fusobacterium necrophorum infections in mice, Infection and Immunity, 15, 510-517.
3. Emery, D., Vaughan, J., Clark, B., Stewart, D., 1986. Virulence determinants of Fusobacterium necrophorum and their prophylactic potentialin animals, Australian veterinary journal, 12, 267-274.
4. Garcia, M., Alexander, D.C., McKay, K., 1975. Biological characterization of Fusobacterium necrophorum cell fractions in preparation for toxin and immunization studies, Infection and immunity, 11, 606-616.
5. Garcia, M., McKay, K., 1978. Intraperitoneal immunization against necrobacillosis in experimental animals, Canadian journal of comparative medicine, 42, 121-127.
6. Li, Y., 2000. New technologies and experiences of animal footrot disease, Contemporary livestock, 4, 5-26. In Chinese.
7. Nagaraja, T., Lechtenberg, K., 2007. Liver abscesses in feedlot cattle, The Veterinary clinics of North America. Food animal practice, 23, 351-369. doi: 10.1016/j.cvfa.2007.05.002
8. Narayanan, S., Chengappa, M., Stewart, G., Nagaraja, T., 2003. Immunogenicity and protective effects of truncated recombinant leukotoxin proteins of Fusobacterium necrophorum in mice, Veterinary microbiology, 93, 335-347. doi: 10.1016/S0378-1135(03)00045-2
9. Narayanan, S., Nagaraja, T., Chengappa, M., Stewart, G., 2001. Cloning, sequencing, and expression of the leukotoxin gene from Fusobacterium necrophorum, Infection and Immunity, 69, 5447-5455. doi: 10.1128/ IAI.69.9.5447-5455.2001
10. Saginala, S., Nagaraja, T., Lechtenberg, K., Chengappa, M., Kemp, K., Hine, P., 1997. Effect of Fusobacterium necrophorum leukotoxin vaccine on susceptibility to experimentally induced liver abscesses in cattle, Journal of animal science, 75, 1160-1166.
11. Smith, G., Thornton, E., 1993. Pathogenicity of Fusobacterium necrophorum strains from man and animals, Epidemiology and Infection, 110, 499-506.
12. Tan, Z., Nagaraja, T., Chengappa, M., 1996. Fusobacterium necrophorum infections: Virulence factors, pathogenic mechanism and control measures, Veterinary research communications, 20, 113-140. doi: 10.1007/ BF00385634
13. Tan, Z., Nagaraja, T., Chengappa, M., Smith, J., 1994. Biological and biochemical characterization of Fusobacterium necrophorum leukotoxin, American journal of veterinary research, 55, 515-521.