CCR5 signalling, but not DARC or D6 regulatory, chemokine receptors are targeted by herpesvirus U83A chemokine which delays receptor internalisation via diversion to a caveolin-linked pathway

Journal of Inflammation

Volumn 6, Issue , 2009, Pages

  Catusse, Julie ^a   Clark, David J ^a   Gompels, Ursula A ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; CAVEOLIN 1; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CCR8; CHEMOKINE RECEPTOR D6; CLATHRIN; DUFFY ANTIGEN RECEPTOR FOR CHEMOKINES; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; U83A CHEMOKINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BINDING AFFINITY; CELL STRAIN COS7; CHEMOTAXIS; CONFOCAL MICROSCOPY; ENDOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN HERPESVIRUS 6; LEUKOCYTE; NONHUMAN; SIGNAL TRANSDUCTION;

HERPESVIRIDAE; HUMAN HERPESVIRUS 6A;

EID: 70349251322     PISSN: None     EISSN: 14769255     Source Type: Journal    
DOI: 10.1186/1476-9255-6-22     Document Type: Article

References (52)

1. Human herpesviruses 6 and 7. UA Gompels, Encyclopedia of Virology Oxford: Elsevier, Mahy BWJ, Van Regenmortel MHV, third 2008 2 498 505 http://www.sciencedirect.com/science/referenceworks/9780123744104
2. Identification and characterization of U83A viral chemokine, a broad and potent beta-chemokine agonist for human CCRs with unique selectivity and inhibition by spliced isoform. DR Dewin J Catusse UA Gompels, J Immunol 2006 176 544 56 16365449
3. The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution. UA Gompels J Nicholas G Lawrence M Jones BJ Thomson ME Martin S Efstathiou M Craxton HA Macaulay, Virology 1995 209 29 51 7747482
4. A highly selective CCR2 chemokine agonist encoded by human herpesvirus 6. HR Luttichau I Clark-Lewis PO Jensen C Moser J Gerstoft TW Schwartz, J Biol Chem 2003 278 10928 33 12554737
5. RANTES binding and down-regulation by a novel human herpesvirus-6 beta chemokine receptor. RS Milne C Mattick L Nicholson P Devaraj A Alcami UA Gompels, J Immunol 2000 164 2396 404 10679075
6. Human herpesvirus 6 (HHV-6) is transmitted from parent to child in an integrated form and characterization of cases with chromosomally integrated HHV-6 DNA. K Tanaka-Taya J Sashihara H Kurahashi K Amo H Miyagawa K Kondo S Okada K Yamanishi, J Med Virol 2004 73 465 73 15170644
7. The prevalence of chromosomally integrated human herpesvirus 6 genomes in the blood of UK blood donors. HN Leong PW Tuke RS Tedder AB Khanom RP Eglin CE Atkinson KN Ward PD Griffiths DA Clark, J Med Virol 2007 79 45 51 17133548
8. Inhibition of HIV-1 infection by viral chemokine U83A via high-affinity CCR5 interactions that block human chemokine-induced leukocyte chemotaxis and receptor internalisation. J Catusse CM Parry DR Dewin UA Gompels, Blood 2007 109 3633 9 17209056
9. Immunomodulation by herpesvirus U51A chemokine receptor via CCL5 and FOG-2 down-regulation plus XCR1 and CCR7 mimicry in human leukocytes. J Catusse J Spinks C Mattick A Dyer K Laing C Fitzsimons MJ Smit UA Gompels, Eur J Immunol 2008 38 763 77 18286574
10. Chemokine-directed trafficking of receptor stimulus to different G proteins: selective inducible and constitutive signaling by human herpesvirus 6-encoded chemokine receptor U51. CP Fitzsimons UA Gompels D Verzijl HF Vischer C Mattick R Leurs MJ Smit, Mol Pharmacol 2006 69 888 98 16332987
11. Novel, nonconsensus cellular splicing regulates expression of a gene encoding a chemokine-like protein that shows high variation and is specific for human herpesvirus 6. C French P Menegazzi L Nicholson H Macaulay D DiLuca UA Gompels, Virology 1999 262 139 51 10489348
12. Regulation of chemotactic networks by 'atypical' receptors. I Comerford W Litchfield Y Harata-Lee RJ Nibbs SR McColl, Bioessays 2007 29 237 47 17295321
13. Postcapillary venule endothelial cells in kidney express a multispecific chemokine receptor that is structurally and functionally identical to the erythroid isoform, which is the Duffy blood group antigen. TJ Hadley ZH Lu K Wasniowska AW Martin SC Peiper J Hesselgesser R Horuk, J Clin Invest 1994 94 985 91 8083383
14. Identification of a promiscuous inflammatory peptide receptor on the surface of red blood cells. K Neote W Darbonne J Ogez R Horuk TJ Schall, J Biol Chem 1993 268 12247 9 8389755
15. Tuning inflammation and immunity by chemokine sequestration: decoys and more. A Mantovani R Bonecchi M Locati, Nat Rev Immunol 2006 6 907 18 17124512
16. Throwing light on DARC. M Pruenster A Rot, Biochem Soc Trans 2006 34 1005 8 17073738
17. The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity. M Pruenster L Mudde P Bombosi S Dimitrova M Zsak J Middleton A Richmond GJ Graham S Segerer RJ Nibbs A Rot, Nat Immunol 2009 10 101 8 19060902
18. Cloning and characterization of a novel promiscuous human beta-chemokine receptor D6. RJ Nibbs SM Wylie J Yang NR Landau GJ Graham, J Biol Chem 1997 272 32078 83 9405404
19. RANTES-induced T cell activation correlates with CD3 expression. DJ Dairaghi KS Soo ER Oldham BA Premack T Kitamura KB Bacon TJ Schall, J Immunol 1998 160 426 33 9552000
20. Glycosaminoglycans mediate cell surface oligomerization of chemokines. AJ Hoogewerf GS Kuschert AE Proudfoot F Borlat I Clark-Lewis CA Power TN Wells, Biochemistry 1997 36 13570 8 9354625
21. Expression of the Duffy antigen in K562 cells. Evidence that it is the human erythrocyte chemokine receptor. A Chaudhuri V Zbrzezna J Polyakova AO Pogo J Hesselgesser R Horuk, J Biol Chem 1994 269 7835 8 8132497
22. A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor. R Horuk CE Chitnis WC Darbonne TJ Colby A Rybicki TJ Hadley LH Miller, Science 1993 261 1182 4 7689250
23. Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent. N Signoret L Hewlett S Wavre A Pelchen-Matthews M Oppermann M Marsh, Mol Biol Cell 2005 16 902 17 15591129
24. Roseoloviruses: human herpesviruses 6 and 7. UA Gompels, Principles and Practice of Clinical Virology Chichester: John Wiley & Sons, Zuckerman AJ, Banatvala JE, Pattison JR, Griffiths PD, Schoub BD, 5 2004 147 168
25. Herpesvirus infections of the nervous system. DH Gilden R Mahalingam RJ Cohrs KL Tyler, Nat Clin Pract Neurol 2007 3 82 94 17279082
26. Cutting edge: the silent chemokine receptor D6 is required for generating T cell responses that mediate experimental autoimmune encephalomyelitis. L Liu GJ Graham A Damodaran T Hu SA Lira M Sasse C Canasto-Chibuque DN Cook RM Ransohoff, J Immunol 2006 177 17 21 16785491
27. Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Y Martinez de la Torre C Buracchi EM Borroni J Dupor R Bonecchi M Nebuloni F Pasqualini A Doni E Lauri C Agostinis R Bulla DN Cook B Haribabu P Meroni D Rukavina L Vago F Tedesco A Vecchi SA Lira M Locati A Mantovani, Proc Natl Acad Sci USA 2007 104 2319 24 17283337
28. Human herpesvirus (HHV)-6 and HHV-7 infections in pregnant women. MT Caserta CB Hall K Schnabel G Lofthus MP McDermott, J Infect Dis 2007 196 1296 303 17922393
29. Congenital infections with human herpesvirus 6 (HHV6) and human herpesvirus 7 (HHV7). CB Hall MT Caserta KC Schnabel C Boettrich MP McDermott GK Lofthus JA Carnahan S Dewhurst, J Pediatr 2004 145 472 7 15480369
30. Serum and cerebrospinal fluid levels of cytokines in acute encephalopathy associated with human herpesvirus-6 infection. T Ichiyama Y Ito M Kubota T Yamazaki K Nakamura S Furukawa, Brain Dev 2008 19114298
31. HHV-6 infection during pregnancy and spontaneous abortion. Y Ando K Kakimoto Y Ekuni M Ichijo, Lancet 1992 340 1289 1359342
32. Congenital infection with human herpesvirus 6 variant B associated with neonatal seizures and poor neurological outcome. M Lanari I Papa V Venturi T Lazzarotto G Faldella L Gabrielli B Guerra MP Landini GP Salvioli, J Med Virol 2003 70 628 32 12794728
33. A role of the Duffy antigen for the maintenance of plasma chemokine concentrations. N Fukuma N Akimitsu H Hamamoto H Kusuhara Y Sugiyama K Sekimizu, Biochem Biophys Res Commun 2003 303 137 9 12646177
34. Temporal expression pattern of Duffy antigen in rheumatoid arthritis: up-regulation in early disease. L Gardner C Wilson AM Patterson B Bresnihan O FitzGerald MA Stone BA Ashton J Middleton, Arthritis Rheum 2006 54 2022 6 16732566
35. The Duffy antigen receptor for chemokines is up-regulated during acute renal transplant rejection and crescentic glomerulonephritis. S Segerer H Regele KM Mac R Kain JP Cartron Y Colin D Kerjaschki D Schlondorff, Kidney Int 2000 58 1546 56 11012889
36. Leukocyte extravasation: chemokine transport and presentation by the endothelium. J Middleton AM Patterson L Gardner C Schmutz BA Ashton, Blood 2002 100 3853 60 12433694
37. Expression of DARC, CXCR3 and CCR5 in giant cell arteritis. H Bruhl V Vielhauer M Weiss M Mack D Schlondorff S Segerer, Rheumatology (Oxford) 2005 44 309 13 15572394
38. Demonstration of HHV-6 antigens in biopsies of kidney transplant recipients with cytomegalovirus infection. I Helantera R Loginov P Koskinen I Lautenschlager, Transpl Int 2008 21 980 984 18564986
39. Presentation, patterns of myocardial damage, and clinical course of viral myocarditis. H Mahrholdt A Wagner CC Deluigi E Kispert S Hager G Meinhardt H Vogelsberg P Fritz J Dippon CT Bock K Klingel R Kandolf U Sechtem, Circulation 2006 114 1581 90 17015795
40. Human herpesvirus 6 subtype A-associated myocarditis with 'apical ballooning'. B Bigalke K Klingel AE May R Kandolf MG Gawaz, Can J Cardiol 2007 23 393 5 17440647
41. Increased expression of CCR5 in experimental autoimmune myocarditis and reduced severity induced by anti-CCR5 monoclonal antibody. X Gong H Feng S Zhang Y Yu J Li J Wang B Guo, J Mol Cell Cardiol 2007 42 781 91 17362985
42. CCR5 internalisation and signalling have different dependence on membrane lipid raft integrity. CM Cardaba JS Kerr A Mueller, Cell Signal 2008 20 1687 94 18573334
43. Ligand-induced partitioning of human CXCR1 chemokine receptors with lipid raft microenvironments facilitates G-protein-dependent signaling. X Jiao N Zhang X Xu JJ Oppenheim T Jin, Mol Cell Biol 2005 25 5752 62 15964828
44. Segregation of heterotrimeric G proteins in cell surface microdomains. G(q) binds caveolin to concentrate in caveolae, whereas G(i) and G(s) target lipid rafts by default. P Oh JE Schnitzer, Mol Biol Cell 2001 12 685 98 11251080
45. CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms. MJ Dolan H Kulkarni JF Camargo W He A Smith JM Anaya T Miura FM Hecht M Mamtani F Pereyra V Marconi A Mangano L Sen R Bologna RA Clark SA Anderson J Delmar RJ O'Connell A Lloyd J Martin SS Ahuja BK Agan BD Walker SG Deeks SK Ahuja, Nat Immunol 2007 8 1324 36 17952079
46. CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation. JF Camargo MP Quinones S Mummidi S Srinivas AA Gaitan K Begum F Jimenez S VanCompernolle D Unutmaz SS Ahuja SK Ahuja, J Immunol 2009 182 171 82 19109148
47. Orchestrating the orchestrators: chemokines in control of T cell traffic. SK Bromley TR Mempel AD Luster, Nat Immunol 2008 9 970 80 18711434
48. Genetic deficiency of chemokine receptor CCR5 is a strong risk factor for symptomatic West Nile virus infection: a meta-analysis of 4 cohorts in the US epidemic. JK Lim CY Louie C Glaser C Jean B Johnson H Johnson DH McDermott PM Murphy, J Infect Dis 2008 197 262 5 18179388
49. Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation. R Bonecchi EM Borroni A Anselmo A Doni B Savino M Mirolo M Fabbri VR Jala B Haribabu A Mantovani M Locati, Blood 2008 112 493 503 18480427
50. The T cell chemokine receptor CCR7 is internalized on stimulation with ELC, but not with SLC. G Bardi M Lipp M Baggiolini P Loetscher, Eur J Immunol 2001 31 3291 7 11745346
51. CC chemokine receptor-3 undergoes prolonged ligand-induced internalisation. N Zimmermann JJ Conkright ME Rothenberg, J Biol Chem 1999 274 12611 8 10212240
52. The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization. A Chakera RM Seeber AE John KA Eidne DR Greaves, Mol Pharmacol 2008 73 1362 70 18230715