Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway.

Biology of reproduction

Volumn 81, Issue 1, 2009, Pages 234-242

  Jin, X L ^a   Chandrakanthan, V ^a   Morgan, H D ^a   O'Neill, C ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; MDM2 PROTEIN, MOUSE; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN MDM2; PROTEIN P53;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; C57BL MOUSE; CBA MOUSE; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; PREGNANCY; SIGNAL TRANSDUCTION; TIME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; EMBRYONIC DEVELOPMENT; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LIGANDS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; MODELS, BIOLOGICAL; ONCOGENE PROTEIN V-AKT; PREGNANCY; PROTO-ONCOGENE PROTEINS C-MDM2; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 70349250520     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)