메뉴 건너뛰기




Volumn 65, Issue 10, 2009, Pages 999-1006

Effect of ritonavir on the pharmacokinetics of the benzimidazoles albendazole and mebendazole: An interaction study in healthy volunteers

Author keywords

Albendazole; Benzimidazoles; Drug interaction; Mebendazole; Ritonavir

Indexed keywords

ALBENDAZOLE; MEBENDAZOLE; RITONAVIR;

EID: 70349246420     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-009-0683-y     Document Type: Article
Times cited : (26)

References (27)
  • 1
    • 0029811586 scopus 로고    scopus 로고
    • Cestodes. Echinococcus
    • DOI 10.1016/S0889-8553(05)70268-5
    • RW Ammann J Eckert 1996 Cestodes. Echinococcus Gastroenterol Clin North Am 25 3 655 689 8863045 10.1016/S0889-8553(05)70268-5 1:STN:280: DyaK2s%2Fhs1Cisg%3D%3D (Pubitemid 26335828)
    • (1996) Gastroenterology Clinics of North America , vol.25 , Issue.3 , pp. 655-689
    • Ammann, R.W.1    Eckert, J.2
  • 4
    • 0022521656 scopus 로고
    • Pharmacokinetics of albendazole in man
    • 3770064 10.1007/BF00608219 1:CAS:528:DyaL28XmtFyhsb8%3D
    • SE Marriner DL Morris B Dickson JA Bogan 1986 Pharmacokinetics of albendazole in man Eur J Clin Pharmacol 30 6 705 708 3770064 10.1007/BF00608219 1:CAS:528:DyaL28XmtFyhsb8%3D
    • (1986) Eur J Clin Pharmacol , vol.30 , Issue.6 , pp. 705-708
    • Marriner, S.E.1    Morris, D.L.2    Dickson, B.3    Bogan, J.A.4
  • 5
  • 6
    • 0029009850 scopus 로고
    • Small intestinal sulphoxidation of albendazole
    • 7571717 10.3109/00498259509061863 1:CAS:528:DyaK2MXmsFCjsbw%3D
    • C Villaverde AI Alvarez P Redondo J Voces JL Del Estal JG Prieto 1995 Small intestinal sulphoxidation of albendazole Xenobiotica 25 5 433 441 7571717 10.3109/00498259509061863 1:CAS:528:DyaK2MXmsFCjsbw%3D
    • (1995) Xenobiotica , vol.25 , Issue.5 , pp. 433-441
    • Villaverde, C.1    Alvarez, A.I.2    Redondo, P.3    Voces, J.4    Del Estal, J.L.5    Prieto, J.G.6
  • 7
    • 0034035244 scopus 로고    scopus 로고
    • Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes
    • DOI 10.1046/j.1365-2125.2000.00170.x
    • HC Rawden GO Kokwaro SA Ward G Edwards 2000 Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes Br J Clin Pharmacol 49 4 313 322 10759686 10.1046/j.1365-2125.2000.00170.x 1:CAS:528:DC%2BD3cXjtl2hsb8%3D (Pubitemid 30195273)
    • (2000) British Journal of Clinical Pharmacology , vol.49 , Issue.4 , pp. 313-322
    • Rawden, H.C.1    Kokwaro, G.O.2    Ward, S.A.3    Edwards, G.4
  • 9
    • 0042383336 scopus 로고    scopus 로고
    • Intestinal elimination of albendazole sulfoxide: Pharmacokinetic effects of inhibitors
    • DOI 10.1016/S0378-5173(03)00369-7
    • G Merino AJ Molina JL Garcia MM Pulido JG Prieto AI Alvarez 2003 Intestinal elimination of albendazole sulfoxide: pharmacokinetic effects of inhibitors Int J Pharm 263 1-2 123 132 12954187 10.1016/S0378-5173(03)00369-7 1:CAS:528:DC%2BD3sXmvValtLs%3D (Pubitemid 37087939)
    • (2003) International Journal of Pharmaceutics , vol.263 , Issue.1-2 , pp. 123-132
    • Merino, G.1    Molina, A.J.2    Garcia, J.L.3    Pulido, M.M.4    Prieto, J.G.5    Alvarez, A.I.6
  • 10
    • 0023272305 scopus 로고
    • Cimetidine increases serum mebendazole concentrations. Implications for treatment of hepatic hydatid cysts
    • 3663452 1:STN:280:DyaL1c%2FisVKksA%3D%3D
    • A Bekhti J Pirotte 1987 Cimetidine increases serum mebendazole concentrations. Implications for treatment of hepatic hydatid cysts Br J Clin Pharmacol 24 3 390 392 3663452 1:STN:280:DyaL1c%2FisVKksA%3D%3D
    • (1987) Br J Clin Pharmacol , vol.24 , Issue.3 , pp. 390-392
    • Bekhti, A.1    Pirotte, J.2
  • 11
    • 0025342998 scopus 로고
    • The metabolism of benzimidazole anthelmintics
    • DOI 10.1016/0169-4758(90)90228-V
    • DW Gottschall VJ Theodorides R Wang 1990 The metabolism of benzimidazole anthelmintics Parasitol Today 6 4 115 124 15463313 10.1016/0169-4758(90)90228-V 1:CAS:528:DyaK3cXksFWru7g%3D (Pubitemid 20131120)
    • (1990) Parasitology Today , vol.6 , Issue.4 , pp. 115-124
    • Gottschall, D.W.1    Theodorides, V.J.2    Wang, R.3
  • 12
    • 0022898437 scopus 로고
    • Treatment of hydatid disease with high oral doses of mebendazole. Long-term follow-up of plasma mebendazole levels and drug interactions
    • DOI 10.1007/BF00613522
    • PJ Luder B Siffert F Witassek F Meister J Bircher 1986 Treatment of hydatid disease with high oral doses of mebendazole. Long-term follow-up of plasma mebendazole levels and drug interactions Eur J Clin Pharmacol 31 4 443 448 3816925 10.1007/BF00613522 1:STN:280:DyaL2s7jtlOqsA%3D%3D (Pubitemid 17018784)
    • (1986) European Journal of Clinical Pharmacology , vol.31 , Issue.4 , pp. 443-448
    • Luder, P.J.1    Siffert, B.2    Witassek, F.3
  • 13
    • 13244299150 scopus 로고    scopus 로고
    • Mechanism-based inactivation of CYP3A by HIV protease inhibitors
    • DOI 10.1124/jpet.104.075416
    • CS Ernest 2nd SD Hall DR Jones 2005 Mechanism-based inactivation of CYP3A by HIV protease inhibitors J Pharmacol Exp Ther 312 2 583 591 15523003 10.1124/jpet.104.075416 1:CAS:528:DC%2BD2MXhsVCnsb0%3D (Pubitemid 40189555)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.312 , Issue.2 , pp. 583-591
    • Ernest II, C.S.1    Hall, S.D.2    Jones, D.R.3
  • 14
  • 15
    • 34748887980 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: Implications for predicting clinical drug interactions
    • DOI 10.1124/dmd.107.016089
    • V Dixit N Hariparsad F Li P Desai KE Thummel JD Unadkat 2007 Cytochrome P450 enzymes and transporters induced by anti-HIV protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions Drug Metab Dispos 35 1853 1859 17639026 10.1124/dmd.107.016089 1:CAS:528:DC%2BD2sXhtFansbbL (Pubitemid 47481578)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.10 , pp. 1853-1859
    • Dixit, V.1    Hariparsad, N.2    Li, F.3    Desai, P.4    Thummel, K.E.5    Unadkat, J.D.6
  • 16
    • 33745433348 scopus 로고    scopus 로고
    • Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers
    • 16639344 1:CAS:528:DC%2BD28XlsFGqtrY%3D
    • RF Yeh VE Gaver KB Patterson NL Rezk F Baxter-Meheux MJ Blake JJ Eron Jr CE Klein JC Rublein AD Kashuba 2006 Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers J Acquir Immune Defic Syndr 42 1 52 60 16639344 1:CAS:528:DC%2BD28XlsFGqtrY%3D
    • (2006) J Acquir Immune Defic Syndr , vol.42 , Issue.1 , pp. 52-60
    • Yeh, R.F.1    Gaver, V.E.2    Patterson, K.B.3    Rezk, N.L.4    Baxter-Meheux, F.5    Blake, M.J.6    Eron Jr, J.J.7    Klein, C.E.8    Rublein, J.C.9    Kashuba, A.D.10
  • 18
    • 0036381576 scopus 로고    scopus 로고
    • Effect of gender in the disposition of albendazole metabolites in humans
    • 12242599 10.1007/s00228-002-0488-8 1:CAS:528:DC%2BD38XntFensb0%3D
    • A Mirfazaelian S Dadashzadeh MR Rouini 2002 Effect of gender in the disposition of albendazole metabolites in humans Eur J Clin Pharmacol 58 6 403 408 12242599 10.1007/s00228-002-0488-8 1:CAS:528:DC%2BD38XntFensb0%3D
    • (2002) Eur J Clin Pharmacol , vol.58 , Issue.6 , pp. 403-408
    • Mirfazaelian, A.1    Dadashzadeh, S.2    Rouini, M.R.3
  • 20
    • 0037040378 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG study A5047
    • DOI 10.1097/00002030-200203080-00008
    • CJ Fichtenbaum JG Gerber SL Rosenkranz Y Segal JA Aberg T Blaschke B Alston F Fang B Kosel F Aweeka 2002 Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047 Aids 16 4 569 577 11873000 10.1097/00002030-200203080-00008 1:CAS:528:DC%2BD38XivVyhsrs%3D (Pubitemid 34218852)
    • (2002) AIDS , vol.16 , Issue.4 , pp. 569-577
    • Fichtenbaum, C.J.1    Gerber, J.G.2    Rosenkranz, S.L.3    Segal, Y.4    Aberg, J.A.5    Blaschke, T.6    Alston, B.7    Fang, F.8    Kosel, B.9    Aweeka, F.10
  • 21
    • 70349230524 scopus 로고    scopus 로고
    • Drug interaction studies: Study design, data analysis, and implications for dosing and labeling
    • FDA FDA, Washington DC
    • FDA (2006) Guidance for industry. Drug interaction studies: study design, data analysis, and implications for dosing and labeling. FDA, Washington DC
    • (2006) Guidance for Industry
  • 22
    • 0141483123 scopus 로고    scopus 로고
    • 450s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data
    • DOI 10.1007/s00228-003-0636-9
    • XQ Li A Bjorkman TB Andersson LL Gustafsson CM Masimirembwa 2003 Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data Eur J Clin Pharmacol 59 5-6 429 442 12920490 10.1007/s00228-003-0636-9 1:CAS:528: DC%2BD3sXnt1KitrY%3D (Pubitemid 37214951)
    • (2003) European Journal of Clinical Pharmacology , vol.59 , Issue.5-6 , pp. 429-442
    • Li, X.-Q.1    Bjorkman, A.2    Andersson, T.B.3    Gustafsson, L.L.4    Masimirembwa, C.M.5
  • 23
    • 17844369140 scopus 로고    scopus 로고
    • Transport of anthelmintic benzimidazole drugs by breast cancer resistance protein (BCRP/ABCG2)
    • DOI 10.1124/dmd.104.003319
    • G Merino JW Jonker E Wagenaar MM Pulido AJ Molina AI Alvarez AH Schinkel 2005 Transport of anthelmintic benzimidazole drugs by breast cancer resistance protein (BCRP/ABCG2) Drug Metab Dispos 33 5 614 618 15703302 10.1124/dmd.104.003319 1:CAS:528:DC%2BD2MXkt1Cmtrc%3D (Pubitemid 40593873)
    • (2005) Drug Metabolism and Disposition , vol.33 , Issue.5 , pp. 614-618
    • Merino, G.1    Jonker, J.W.2    Wagenaar, E.3    Pulido, M.M.4    Molina, A.J.5    Alvarez, A.I.6    Schinkel, A.H.7
  • 24
    • 48249104628 scopus 로고    scopus 로고
    • Induction effects of ritonavir: Implications for drug interactions
    • 18577765 10.1345/aph.1K615 1:CAS:528:DC%2BD1cXps1GqsLk%3D
    • MM Foisy EM Yakiwchuk CA Hughes 2008 Induction effects of ritonavir: implications for drug interactions Ann Pharmacother 42 7 1048 1059 18577765 10.1345/aph.1K615 1:CAS:528:DC%2BD1cXps1GqsLk%3D
    • (2008) Ann Pharmacother , vol.42 , Issue.7 , pp. 1048-1059
    • Foisy, M.M.1    Yakiwchuk, E.M.2    Hughes, C.A.3
  • 25
    • 17644364027 scopus 로고    scopus 로고
    • Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers
    • DOI 10.1002/jbt.20058
    • CM Smith SR Faucette H Wang EL LeCluyse 2005 Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers J Biochem Mol Toxicol 19 2 96 108 15849716 10.1002/jbt.20058 1:CAS:528:DC%2BD2MXjvFSlurw%3D (Pubitemid 40571690)
    • (2005) Journal of Biochemical and Molecular Toxicology , vol.19 , Issue.2 , pp. 96-108
    • Smith, C.M.1    Faucette, S.R.2    Wang, H.3    LeCluyse, E.L.4
  • 27
    • 0034437525 scopus 로고    scopus 로고
    • Effect of dose increase or cimetidine co-administration on albendazole bioavailability
    • 11421376 1:CAS:528:DC%2BD3MXkvFeitb0%3D
    • HG Schipper RP Koopmans J Nagy JJ Butter PA Kager CJ Van Boxtel 2000 Effect of dose increase or cimetidine co-administration on albendazole bioavailability Am J Trop Med Hyg 63 5-6 270 273 11421376 1:CAS:528: DC%2BD3MXkvFeitb0%3D
    • (2000) Am J Trop Med Hyg , vol.63 , Issue.56 , pp. 270-273
    • Schipper, H.G.1    Koopmans, R.P.2    Nagy, J.3    Butter, J.J.4    Kager, P.A.5    Van Boxtel, C.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.