Saccade trajectories evoked by sequential and colliding stimulation of the monkey superior colliculus

Brain Research

Volumn 1295, Issue , 2009, Pages 99-118

  Noto, Christopher T ^b   Gnadt, James W ^a,b  

^a HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

Author keywords

Burst generator; Eye movement; Movement curvature; Saccade model; Tortuosity

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; FEMALE; MOTOR CORTEX; NONHUMAN; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; SUPERIOR COLLICULUS;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; ANIMALS; BRAIN; ELECTRIC STIMULATION; ELECTRODES, IMPLANTED; ELECTROPHYSIOLOGY; FEMALE; FIXATION, OCULAR; MACACA MULATTA; MACACA RADIATA; MICROELECTRODES; MODELS, NEUROLOGICAL; NERVE NET; NEURONS; PHOTIC STIMULATION; SACCADES; SIGNAL PROCESSING, COMPUTER-ASSISTED; SUPERIOR COLLICULI; VISUAL PATHWAYS;

EID: 70349238560     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.07.069     Document Type: Article

References (63)

1. Aizawa H., and Wurtz R.H. Reversible inactivation of monkey superior colliculus. I. Curvature of saccadic trajectory. J. Neurophysiol. 79 4 (1998) 2082-2096
2. Anderson R.W., Keller E.L., Gandhi N.J., and Das S. Two-dimensional saccade-related population activity in superior colliculus in monkey. J. Neuorphysil. 80 2 (1998) 798-817
3. Arai K., and Keller E.L. A model of the saccade-generating system that accounts for trajectory variations produced by competing visual stimuli. Biol. Cybern. 92 1 (2005) 21-37
4. Arai K., McPeek R.M., and Keller E.L. Properties of saccadic responses in monkey when multiple competing visual stimuli are present. J. Neurophysiol. 91 2 (2004) 890-900
5. Brecht M., Singer W., and Engel A.K. Amplitude and direction of saccadic eye movements depend on the synchronicity of collicular population activity. J. Neurophysiol. 92 (2004) 424-432
6. Breznen B., Lu S.M., and Gnadt J.W. Analysis of the step response of the saccadic feedback: system behavior. Exp. Brain Res. 111 (1996) 337-344
7. Breznen B., and Gnadt J.W. Analysis of the step response of the saccadic feedback: computational models. Exp. Brain Res. 117 (1997) 181-192
8. Bergeron A., and Guitton D. In multiple-step gaze shifts: omnipause (OPNs) and collicular fixation neurons encode gaze position error; OPNs gate saccades. J. Neurophysiol. 88 (2002) 1726-1742
9. Carasig D., and Gnadt J.W. Experimental manipulations of the spatio-temporal patterns in the collicular motor map. Soc. Neurosci. Abstr. 16 (2004) 880
10. Corneil B.D., Hing C.A., Bautista D.V., and Munoz D.P. Human eye-head gaze shifts in a distractor task I. Truncated gaze shifts. J. Neurophysiol. 82 3 (1999) 1390-1405
11. Cullen K.E., and Guitton D. Analysis of primate IBN spike trains using system identification techniques. I. Relationship to eye movement dynamics during head-fixed saccades. J. Neurophysiol. 78 6 (1997) 3259-3282
12. Findlay J.M. Global visual processing for saccadic eye movements. Vision Res. 22 8 (1982) 1033-1045
13. Freedman E.G., Stanford T.R., and Sparks D.L. Combined eye-head gaze shifts produced by electrical stimulation of the superior colliculus in rhesus monkeys. J. Neurophysiol. 76 2 (1996) 927-952
14. Gamlin P.D.R., Gnadt J.W., and Mays L.E. Abducens internuclear neurons carry an inappropriate signal for ocular convergence. J. Neurophysiol. 62 (1989) 70-81
15. Gandhi N.J., and Keller E.L. Activity of brain stem omnipause neurons during saccades perturbed by stimulation of the primate superior colliculus. J. Neurophysiol. 82 6 (1999) 3254-3267
16. Gnadt J.W., Jackson M.E., and Litvak O. Analysis of the frequency response of the saccadic circuit: system behavior. J. Neurophysiol. 86 (2001) 724-740
17. Goossens H.H., and Van Opstal A.J. Dynamic ensemble coding of saccades in the monkey superior colliculus. J. Neurophysiol. 95 4 (2006) 2326-2341
18. Goossens H.H., and Van Opstal A.J. Local feedback signals are not distorted by prior eye movements: evidence from visually evoked double saccades. J. Neurophysiol. 78 1 (1997) 533-538
19. Grisan E., Foracchia M., and Ruggeri A. A novel method for the automatic grading of retinal vessel tortuosity. IEEE Trans. Med. Imaging 27 3 (2008) 310-319
20. Hafed Z.M., Goffart L., and Krauzlis R.J. A neural mechanism for microsaccade generation in the primate superior colliculus. Science 323 5916 (2009) 940-943
21. Hikosaka O., and Wurtz R.H. Visual and oculumotor functions of monkey substantia nigra pars reticulata. IV. Relation of substantia nigra to superior colliculus. J Neurophysiol. 49 5 (1983) 1285-1301
22. Jackson M.E., Litvak O., and Gnadt J.W. Analysis of the frequency response of the saccadic circuit: numerical simulations. Neural Net. 14 (2001) 1357-1376
23. Judge S.J., Richmond B.J., and Chu F.C. Implantation of magnetic search coils for measurement of eye position: an improved method. Vision Res. 20 (1980) 535-538
24. Jürgens R., Becker W., and Kornhuber H.H. Natural and drug induced variations of velocity and duration of human saccadic eye movements: evidence for a control of the neural pulse generator by local feedback. Biol. Cybern. 39 (1981) 87-96
25. Keller E.L., Gandhi N.J., and Vijay Sekaran S. Activity in deep intermediate layer collicular neuorns during interrupted saccades. Exp. Brain Res. 130 2 (2000) 227-237
26. Keller E.L., Lee K.M., and McPeek R.M. Readout of higher-level processing in the discharge of superior colliculus neurons. Ann. N.Y. Acad. Sci. 1039 (2005) 198-208
27. Kustov A.A., and Robinson D.L. Modified saccades evoked by stimulation of the macaque superior colliculus account for properties of the resettable integrator. J. Neurophysiol. 73 (1995) 1724-1728
28. Lee C., Rohrer W.H., and Sparks D.L. Population coding of saccadic eye movements by neurons in the superior colliculus. Nature 332 6162 (1988) 357-360
29. Liu P., and Basso M.A. Substantia nigra influences monkey superior colliculus activity bilaterally. J. Neurophysiol. 100 2 (2008) 1098-1112
30. McIlwain J.T. Lateral spread of neural excitation during microstimulation in intermediate gray layer of cat's superior colliculus. J. Neurophysiol. 47 2 (1982) 167-178
31. McPeek R.M. Incomplete suppression of distracter-related activity in the frontal eye field results in curved saccades. J. Neurophysiol. 96 5 (2006) 2699-2711
32. McPeek R.M., and Keller E.L. Short-term priming, concurrent processing, and saccade curvature during a target selection task in the monkey. Vision Res. 41 6 (2001) 785-800
33. McPeek R.M., Skavenski A.A., and Nakayama K. Concurrent processing of saccades in visual search. Vision Res. 40 (2000) 2499-2516
34. Moschovakis A.K., Scudder C.A., and Highstein S.M. The microscopic anatomy and physiology of the mammalian saccadic system. Prog. Neurobio. 50 (1996) 133-264
35. Munoz D.P., and Istvan P.J. Lateral inhibitory interactions in the intermediate layers of the monkey superior colliculus. J. Neurophysiol. 79 3 (1998) 1193-1209
36. Munoz D.P., and Wurtz R.H. Role of the rostral superior colliculus in active visual fixation and execution of express saccades. J. Neurophysiol. 67 (1992) 1000-1002
37. Munoz D.P., and Wurtz R.H. Saccade-related activity in monkey superior colliculus. I. Characteristics of burst and buildup cells. J. Neurophysiol. 73 (1995) 2313-2333
38. Munoz D.P., and Wurtz R.H. Saccade-related activity in monkey superior colliculus. II. Spread of activity during saccades. J. Neurophysiol. 73 6 (1995) 2334-2348
39. Nichols M.J., and Sparks D.L. Nonstationary properties of the saccadic system: new constraints on models of saccadic control. J. Neurophysiol. 73 (1995) 431-435
40. Optican L.M. A field theory of saccade generation: temporal-to-spatial transform in the superior colliculus. Vision Res. 35 23-24 (1995) 3313-3330
41. Optican L.M. Sensorimotor transformation for visually guided saccades. Ann. N.Y. Acad. Sci. 1039 (2005) 132-148
42. Ottes F.P., Van Gisbergen J.A., and Eggermont J.J. Visuomotor fields of the superior colliculus: a quantitative model. Vision Res. 26 6 (1986) 857-873
43. Ottes F.P., Van Gisbergen J.A., Eggermont J.J. (1984) Metrics of saccade responses to visual double stimuli: two different modes. 24(10):1169-79.
44. Paul K., and Gnadt J.W. Activity of omnipause neurons during staircase saccades elicited by persistent microstimulation of the superior colliculus. Vision Res. 46 (2006) 3430-3442
45. Port N.L., and Wurtz R.H. Sequential activity of simultaneously recorded neurons in the superior colliculus during curved saccades. J. Neurophysiol. 90 3 (2003) 1887-1903
46. Ramcharan E.J., Gnadt J.W., Sherman S.M. (2003) Single unit recording in the lateral geniculate nucleus of the awake behaving monkey. Methods, Recording in awake and freely moving animals 30:142-151.
47. Robinson D.A. A method of measuring eye movement using a scleral search coil in a magnetic field. IEEE Trans. Biomed. Eng. 10 (1963) 137-145
48. Robinson D.A. Eye movements evoked by collicular stimulation in the alert monkey. Vision Res. 12 (1972) 1795-1808
49. Robinson D.A. Ocular control signals. Basic Mechanisms of Ocular Motility and their Clinical Implications (1975), Pergamon Press, Oxford 337-374
50. Roucoux A., Guitton D., and Crommelinck M. Stimulation of the superior colliculus in the alert cat. II. Eye and head movements when the head is unrestrained. Exp. Brain Res. 39 (1980) 75-85
51. Schiller P.H., and Koerner F. Discharge characteristics of single units in the superior colliculus of the alert rhesus monkey. J. Neurophysiol. 34 (1971) 920-936
52. Schlag J., Pouget A., Sadeghpour S., and Schlag-Rey M. Interactions between natural and electrically evoked saccades. III. Is the nonstationarity the result of an integrator not instantaneously reset?. J. Neurophysiol. 79 2 (1998) 903-910
53. Scudder C.A., Kaneko C.S., and Fuchs A.F. The brainstem burst generator for saccadic eye movements: a modern synthesis. Exp. Brain Res. 142 4 (2002) 439-462
54. Soetedjo R., Kaneko C.R., and Fuchs A.F. Evidence that the superior colliculus participates in the feedback control of saccadic eye movements. J. Neurophysiol. 87 2 (2002) 679-695
55. Sparks D.L., Holland R., and Guthrie B.L. Size and distribution of movement fields in the monkey superior colliculus. Brain Res. 113 (1976) 21-34
56. Stanford T.R., Freedman E.G., and Sparks D.L. Site and parameters of microstimulation: evidence for independent effects on the properties of saccades evoked from the primate superior colliculus. J. Neurophysiol. 76 5 (1996) 3360-3381
57. Van Gisbergen J.A., Van Opstal A.J., and Tax A.A. Collicular ensemble coding of saccades based on vector summation. Neuroscience 21 2 (1987) 541-555
58. van Opstal A.J., and Goossens H.H.L.M. Linear ensemble-coding in midbrain superior colliculus specifies the saccade kinematics. Biol. Cybern. 98 (2008) 561-577
59. van Opstal A.J., and van Gisbergen J.A. Role of monkey superior colliculus in saccade averaging. Exp. Brain Res. 79 1 (1990) 143-149
60. Waitzman D.M., Pathmanathan J., Presnell R., Ayers A., and DePalma S. Contribution of the superior colliculus and the mesencephalic reticular formation to gaze control. Ann. N.Y. Acad. Sci. 956 (2002) 111-129
61. Walton M.M., Sparks D.L., and Gandhi N.J. Simulations of saccade curvature by models that place superior colliculus upstream from the local feedback loop. J. Neurophysiol. 93 4 (2005) 2354-8235
62. Watanabe M., Kobayashi Y., Inoue Y., and Isa T. Effects of local nicotinic activation of the superior colliculus on saccades in monkeys. J. Neurophysiol. 93 1 (2005) 519-534
63. Wurtz R.H., and Goldberg M.E. Superior colliculus cell responses related to eye movements in awake monkeys. Science 171 966 (1971) 82-84