Enantiomeric purity control of levocetirizine in pharmaceuticals using anionic cyclodextrin mediated capillary electrophoresis separation and fiber-based diode array detection

Pharmazie

Volumn 64, Issue 7, 2009, Pages 423-427

  Mikuš, Peter ^a   Marakova K ^a   Valaskova I ^a   Havranek E ^a  

^a Physics and Informatics   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CYCLODEXTRIN; CETIRIZINE; DEXTROCETIRIZINE; LEVOCETIRIZINE; UNCLASSIFIED DRUG; ANION; CYCLODEXTRIN; HISTAMINE H1 RECEPTOR ANTAGONIST;

ACCURACY; ARTICLE; CALIBRATION; CAPILLARY ELECTROPHORESIS; CORRELATION COEFFICIENT; DIODE; DRUG DETERMINATION; DRUG PURITY; ENANTIOMER; ENANTIOSELECTIVITY; QUANTITATIVE ANALYSIS; RELIABILITY; SEPARATION TECHNIQUE; STANDARD; ULTRAVIOLET SPECTROSCOPY; VALIDATION STUDY; CHEMISTRY; QUALITY CONTROL; REPRODUCIBILITY; STEREOISOMERISM; TABLET;

ANIONS; CETIRIZINE; CYCLODEXTRINS; ELECTROPHORESIS, CAPILLARY; HISTAMINE H1 ANTAGONISTS, NON-SEDATING; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM; TABLETS;

EID: 70349235863     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2009.9091     Document Type: Article

References (15)

1. Bonato PS (2003) Recent advances in the determination of enantiomeric drugs and their metabolites in biological fluids by capillary electrophoresis-mediated microanalysis. Electrophoresis 24: 4078-4094.
2. Chou YW, Huang WS, Ko CC, Chen SH (2008) Enantioseparation of cetirizine by sulfated-beta-cyclodextrin-mediated capillary electrophoresis. J Sep Sci 31: 845-852.
3. th ed., Lippincott, Philadelphia, p. 5-38
4. Eeckhaut A, Michotte Y (2006) Chiral separation of cetirizine by capillary electrophoresis. Electrophoresis 27: 2376-2385.
5. Huang X, Coleman WF, Zare RN (1989) Analysis of factors causing peak broadening in capillary zone electrophoresis. J Chromatogr 480: 95-110.
6. ICH Harmonised Tripartite Guideline: Validation of Analytical Procedures Q2 (R1) Step 4 Version, 2005.
7. Innes IR, Nickersen M (1970), in: Goodman LS, Gilman A (eds.) The pharmacological basis of therapeutics, MacMillan Publishing Co., Inc., New York, p. 477-513
8. Mikuš P, Valášková I, Havránek E (2005) Enantioselective analysis of cetirizine in pharmaceuticals by cyclodextrin-mediated capillary electrophoresis. J Sep Sci 28: 1278-1284.
9. rd ed., Ellis Horwood Ltd., Chichester
10. Oppenheimer JJ, Casale TB (2002) Next generation antihistamines: therapeutic rationale, accomplishments and advances. Expert Opin Investig Drugs 11: 807-817.
11. Peng D, Xiao SY, Shi KY Mu XJ, Zhang R, Xia ZN (2006) Chiral separation and quantitative analysis of cetirizine by capillary electrophoresis in the medium of dextrins. Chin J Anal Chem 34: 1667-1667.
12. Preinerstorfer B, Lämmerhofer M, Lindner W (2009) Advances in enantio-selective separations using electromigration capillary techniques. Electrophoresis 30: 100-132.
13. Savitzky A, Golay MJE (1964) Smoothing and differentiation of data by simplified least-squares procedures. Anal Chem 36: 1627-1639.
14. Strašík S, Danková M, Molnárová M, Ölvecká E, Kaniansky D (2003) Capillary zone electrophoresis in wide bore capillary tubes with fiber-coupled diode array detection. J Chromatogr A 990: 23-33.
15. Ward TJ, Hamburg DM (2004) Chiral separations. Anal Chem 76: 4635-4644.