Tumor-associated epilepsy

Neurosurgical Focus

Volumn 27, Issue 2, 2009, Pages

  Rajneesh, Kiran F ^a   Binder, Devin K ^a,b  

^a Department of Neurological Surgery ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain tumor; Epilepsy; Pathophysiology; Seizure; Tumor associated seizure

Indexed keywords

ANTICONVULSIVE AGENT;

BRAIN; BRAIN TUMOR; DRUG RESISTANCE; EPILEPSY; FOCAL EPILEPSY; GENERALIZED EPILEPSY; HUMAN; PATHOPHYSIOLOGY; REVIEW;

ANTICONVULSANTS; BRAIN; BRAIN NEOPLASMS; DRUG RESISTANCE; EPILEPSIES, PARTIAL; EPILEPSY; EPILEPSY, GENERALIZED; HUMANS;

EID: 70349235642     PISSN: None     EISSN: 10920684     Source Type: Journal    
DOI: 10.3171/2009.5.FOCUS09101     Document Type: Review

References (42)

1. Aronica E, Gorter JA, Jansen GH, Leenstra S, Yankaya B, Troost D. Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex. Acta Neuropathol 101:449-459, 2001.
2. Aronica E, Gorter JA, Redeker S, Ramkema M, Spliet WG, van Rijen PC, et al. Distribution, characterization and clinical significance of microglia in glioneuronal tumours from patients with chronic intractable epilepsy. Neuropathol Appl Neurobiol 31:280-291, 2005.
3. Aronica E, Yankaya B, Jansen GH, Leenstra S, van Veelen CW, Gorter JA, et al. Ionotropic and metabotropic glutamate receptor protein expression in glioneuronal tumours from patients with intractable epilepsy. Neuropathol Appl Neurobiol 27:223-237, 2001.
4. Bateman DE, Hardy JA, McDermott JR, Parker DS, Edwardson JA. Amino acid neurotransmitter levels in gliomas and their relationship to the incidence of epilepsy. Neurol Res 10:112-114, 1988.
5. Becker AJ, Lobach M, Klein H, Normann S, Nothen MM, von Deimling A, et al. Mutational analysis of TSC1 and TSC2 genes in gangliogliomas. Neuropathol Appl Neurobiol 27:105-114, 2001.
6. Binder DK, Podlogar M, Clusmann H, Bien C, Urbadch H, Schramm J, et al. Surgical treatment of parietal lobe epilepsy. Clinical article. J Neurosurg [epub ahead of print, February 6, 2009. DOI: 10.3171/2008.2.17665].
7. Binder DK, Von Lehe M, Kral T, Bien CG, Urbach H, Schramm J, et al. Surgical treatment of occipital lobe epilepsy. J Neurosurg 109:57-69, 2008.
8. Blümcke I, Giencke K, Wardelmann E, Beyenburg S, Kral T, Sarioglu N, et al. The CD34 epitope is expressed in neoplastic and malformative lesions associated with chronic, focal epilepsies. Acta Neuropathol 97:481-490, 1999.
9. Blümcke I, Luyken C, Urbach H, Schramm J, Wiestler OD An isomorphic subtype of long-term epilepsy-associated astrocytomas associated with benign prognosis. Acta Neuropathol 107:381-388, 2004.
10. Cascino GD. Epilepsy and brain tumors: implications for treatment. Epilepsia 31:3 SupplS37-S44, 1990.
11. Clusmann H, Schramm J, Kral T, Helmstaedter C, Ostertun B, Fimmers R, et al. Prognostic factors and outcome after different types of resection for temporal lobe epilepsy. J Neurosurg 97:1131-1141, 2002.
12. Daumas-Duport C, Scheithauer BW, Chodkiewicz JP, Laws ER Jr, Vedrenne C.: Dysembryoplastic neuroepithelial tumor: a surgically curable tumor of young patients with intractable partial seizures. Report of thirty-nine cases. Neurosurgery 23:545-556, 1988.
13. Haglund MM, Berger MS, Kunkel DD, Franck JE, Ghatan S, Ojemann GA. Changes in gamma aminobutyric acid and somatostatin in epileptic cortex associated with low-grade gliomas. J Neurosurg 77:209-216, 1992.
14. Herman ST: Epilepsy after brain insult: targeting epileptogenesis. Neurology 59:9 SupplS21-S26, 2002.
15. Hossmann KA, Seo K, Szymas J, Wechsler W: Quantitative analysis of experimental peritumoral edema in cats. Adv Neurol 52:449-458, 1990.
16. Ivens S, Kaufer D, Flores LP, Bechmann I, Zumsteg D, Tomkins O, et al. TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis. Brain 130:535-547, 2007.
17. Kim E, Lowenson JD, MacLaren DC, Clarke S, Young SG. Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice. Proc Natl Acad Sci U S A 94:6132-6137, 1997.
18. Kohling R. Neuroscience. GABA becomes exciting. Science 298:1350-1351, 2002.
19. Kohling R, Vreugdenhil M, Bracci E, Jefferys JG. Ictal epileptiform activity is facilitated by hippocampal GABAA receptor-mediated oscillations. J Neurosci 20:6820-6829, 2000.
20. Liigant A, Haldre S, Oun A, Linnamagi U, Saar A, Asser T, et al. Seizure disorders in patients with brain tumors. Eur Neurol 45:46-51, 2001.
21. Luyken C, Blumcke I, Fimmers R, Urbach H, Elger CE, Wiestler OD, et al. The spectrum of long-term epilepsy-associated tumors: long-term seizure and tumor outcome and neurosurgical aspects. Epilepsia 44:822-830, 2003.
22. Luyken C, Blumcke I, Fimmers R, Urbach H, Wiestler OD, Schramm J. Supratentorial gangliogliomas: histopathologic grading and tumor recurrence in 184 patients with a median follow-up of 8 years. Cancer 101:146-155, 2004.
23. Lynam LM, Lyons MK, Drazkowski JF, Sirven JI, Noe KH, Zimmerman RS, et al. Frequency of seizures in patients with newly diagnosed brain tumors: a retrospective review. Clin Neurol Neurosurg 109:634-638, 2007.
24. Lyons SA, Chung WJ, Weaver AK, Ogunrinu T, Sontheimer H. Autocrine glutamate signaling promotes glioma cell invasion. Cancer Res 67:9463-9471, 2007.
25. Maas S, Patt S, Schrey M, Rich A. Underediting of glutamate receptor GluR-B mRNA in malignant gliomas. Proc Natl Acad Sci U S A 98:14687-14692, 2001.
26. Mody I, Heinemann U. NMDA receptors of dentate gyrus granule cells participate in synaptic transmission following kindling. Nature 326:701-704, 1987.
27. - transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory. Proc Natl Acad Sci U S A 103:8465-8468, 2006.
28. Palmini A, Najm I, Avanzini G, Babb T, Guerrini R, Foldvary-Schaefer N, et al. Terminology and classification of the cortical dysplasias. Neurology 62:6 SupplS2-S8, 2004.
29. Riva M. Brain tumoral epilepsy: a review. Neurol Sci 26:1 SupplS40-S42, 2005.
30. Rodriguez-Moreno A, Herreras O, Lerma J. Kainate receptors presynaptically downregulate GABAergic inhibition in the rat hippocampus. Neuron 19:893-901, 1997.
31. Schick V, Majores M, Koch A, Elger CE, Schramm J, Urbach H, et al. Alterations of phosphatidylinositol 3-kinase pathway components in epilepsy-associated glioneuronal lesions. Epilepsia 48:5 Suppl65-73, 2007.
32. Schramm J, Luyken C, Urbach H, Fimmers R, Blumcke I. Evidence for a clinically distinct new subtype of grade II astrocytomas in patients with long-term epilepsy. Neurosurgery 55:340-348, 2004.
33. Schwartzkroin PA, Baraban SC, Hochman DW. Osmolarity, ionic flux, and changes in brain excitability. Epilepsy Res 32:275-285, 1998.
34. Sontheimer H. A role for glutamate in growth and invasion of primary brain tumors. J Neurochem 105:287-295, 2008.
35. Sontheimer H. An unexpected role for ion channels in brain tumor metastasis. Exp Biol Med (Maywood) 233:779-791, 2008.
36. Taylor DC, Falconer MA, Bruton CJ, Corsellis JA. Focal dysplasia of the cerebral cortex in epilepsy. J Neurol Neurosurg Psychiatry 34:369-387, 1971.
37. Urbach H, Binder D, von Lehe M, Podlogar M, Bien CG, Becker A, et al. Correlation of MRI and histopathology in epileptogenic parietal and occipital lobe lesions. Seizure 16:608-614, 2007.
38. van Breemen MS, Vecht CJ. Optimal seizure management in brain tumor patients. Curr Neurol Neurosci Rep 5:207-213, 2005.
39. van Breemen MS, Wilms EB, Vecht CJ. Epilepsy in patients with brain tumours: epidemiology, mechanisms, and management. Lancet Neurol 6:421-430, 2007.
40. Wolf HK, Birkholz T, Wellmer J, Blumcke I, Pietsch T, Wiestler OD. Neurochemical profile of glioneuronal lesions from patients with pharmacoresistant focal epilepsies. J Neuropathol Exp Neurol 54:689-697, 1995.
41. Wolf HK, Buslei R, Blumcke I, Wiestler OD, Pietsch T. Neural antigens in oligodendrogliomas and dysembryoplastic neuroepithelial tumors. Acta Neuropathol 94:436-443, 1997.
42. Wolf HK, Roos D, Blumcke I, Pietsch T, Wiestler OD. Perilesional neurochemical changes in focal epilepsies. Acta Neuropathol 91:376-384, 1996.