Structural characterisation and dehydration behaviour of siramesine hydrochloride

Journal of Pharmaceutical Sciences

Volumn 98, Issue 10, 2009, Pages 3596-3607

  Zimmermann, Anne ^a   Tian, Fang ^a   De Diego, Heidi Lopez ^b   Frydenvang, Karla ^a   Rantanen, Jukka ^a   Elema, Michiel Ringkjøbing ^b   Hovgaard, Lars ^a,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b H LUNDBECK A S   (Denmark)

^c NOVO NORDISK A S   (Denmark)

Author keywords

Crystal structure; Dehydration; Intrinsic dissolution rate; Monohydrate; Near infrared spectroscopy (NIR); Raman spectroscopy; Solid state properties; Solubility; Thermal analysis; X ray powder diffractometry (XRPD)

Indexed keywords

CHLORIDE ION; DIGITOXIN; DRUG; SIRAMESINE HYDROCHLORIDE ANHYDRATE; SIRASEMINE HYDROCHLORIDE MONOHYDRATE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; DEHYDRATION; DRUG SOLUBILITY; DRUG STRUCTURE; HYDROGEN BOND; PHYSICAL CHEMISTRY; SPECTROSCOPY; THERMOSTABILITY;

EID: 70349229288     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21679     Document Type: Article

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