Total synthesis of (+)-largazole, a histone deacetylase inhibitor

Chemtracts

Volumn 22, Issue 2, 2009, Pages 50-58

  Yan, Wuming ^a   O'Doherty, George A ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; HISTONE DEACETYLASE INHIBITOR; LARGAZOLE; NATURAL PRODUCT; THIAZOLE; UNCLASSIFIED DRUG;

ALKYLATION; BIOLOGICAL ACTIVITY; CHIRALITY; CYCLIZATION; CYTOTOXICITY; NOTE; RING CLOSING METATHESIS; SAPONIFICATION; STEREOCHEMISTRY; SYNTHESIS;

EID: 70349209217     PISSN: 14319268     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (6)

1. Kanchan, T., Paul, V.J., Luesch, H. J. Am. Chem. Soc. 2008, 130, 1806.
2. Ying, Y., Taori, K., Kim, H., Hong, J., Luesch, H. J. Am. Chem. Soc. 2008, 130, 8455.
3. Ying, Y., Liu, Y., Byeon, S.R., Kim, H., Luesch, H., Hong, J. Org. Lett. 2008, 10, 4021.
4. Kulkami, S., Ghosh, A.K. Org. Lett. 2008, 10, 3907.
5. Nasveschuk, C.G., Ungermannova, D., Liu, X.D., Phillips, A.J. Org. Lett. 2008, 10, 3595.
6. Bowers, A., West, N., Taunton, J., Schreiber, S.L., Bradner, J.E., Williams, R.M. J. Am. Chem. Soc. 2008, 130, 11219.