A New 15-50 MHz Array-Based Micro-Ultrasound Scanner for Preclinical Imaging

Ultrasound in Medicine and Biology

Volumn 35, Issue 10, 2009, Pages 1700-1708

  Foster, F Stuart ^a   Mehi, James ^b   Lukacs, Marc ^a   Hirson, Desmond ^b   White, Chris ^b   Chaggares, Chris ^b   Needles, Andrew ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b Sonics Inc   (Canada)

Author keywords

High frequency arrays; High frequency ultrasound; Micro ultrasound; Mouse imaging; Preclinical imaging

Indexed keywords

HIGH-FREQUENCY ARRAYS; HIGH-FREQUENCY ULTRASOUND; MICRO-ULTRASOUND; MOUSE IMAGING; PRECLINICAL IMAGING;

ACOUSTIC WAVES; FLOW VISUALIZATION; IMAGING SYSTEMS; OPTOELECTRONIC DEVICES; PIEZOELECTRIC TRANSDUCERS; SCANNING; TUMORS; ULTRASONIC DEVICES; ULTRASONIC TRANSMISSION; ULTRASONICS;

ULTRASONIC IMAGING;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIFFRACTION; ECHOGRAPHY; EMBRYO DEVELOPMENT; HEART DEVELOPMENT; IMAGE QUALITY; IMAGING SYSTEM; MOUSE; NONHUMAN; PIEZOELECTRICITY; PLACENTA CIRCULATION; PRIORITY JOURNAL; SIGNAL PROCESSING; TUMOR BLOOD FLOW; TUMOR VASCULARIZATION; ULTRASOUND SCANNER; ULTRASOUND TRANSDUCER;

ANIMALS; AORTA; ECHOCARDIOGRAPHY, DOPPLER; EQUIPMENT DESIGN; HUMANS; MICE; MICROTECHNOLOGY; MODELS, ANIMAL; PHANTOMS, IMAGING; TRANSDUCERS; ULTRASONOGRAPHY, DOPPLER; ULTRASONOGRAPHY, PRENATAL;

EID: 70349194402     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2009.04.012     Document Type: Article

References (25)

1. Brown J.A., Foster F.S., Needles A., Cherin E., and Lockwood G.R. Fabrication and performance of a 40-MHz linear array based on a 1-3 composite with geometric elevation focusing. IEEE Trans Ultrason Ferroelectr Freq Control 54 (2007) 1888-1894
2. Cannata J.M., Williams J.A., Zhou Q., Ritter T.A., and Shung K.K. Development of a 35-MHz piezo-composite ultrasound array for medical imaging. IEEE Trans Ultrason Ferroelectr Freq Control 53 (2006) 224-236
3. Cobbold R. Foundations of Biomedical Ultrasound (2008), Oxford University Press, New York
4. Foster F.S., Zhang M.Y., Zhou Y.Q., Liu G., Mehi J., Cherin E., Harasiewicz K.A., Starkoski B.G., Zan L., Knapik D.A., and Adamson S.L. A new ultrasound instrument for in vivo microimaging of mice. Ultrasound Med Biol 28 (2002) 1165-1172
5. Goessling W., North T.E., and Zon L.I. Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors. Nat Methods 4 (2007) 551-553
6. Ino T., Akimoto K., Ohkubo M., Nishimoto K., Yabuta K., Takaya J., and Yamaguchi H. Application of percutaneous transluminal coronary angioplasty to coronary arterial stenosis in Kawasaki disease. Circulation 93 (1996) 1709-1715
7. Jensen J.A. Simulation of advanced ultrasound systems using Field II 2004. IEEE International Symposium on Biomedical Engineering 1 (2004) 636-639
8. Johnson J., Oralkan O., Demirci U., Ergun S., Karaman M., and Khuri-Yakub P. Medical imaging using capacitive micromachined ultrasonic transducer arrays. Ultrasonics 40 (2002) 471-476
9. Kiguchi K., Ruffino L., Kawamoto T., Franco E., Kurakata S., Fujiwara K., Hanai M., Rumi M., and DiGiovanni J. Therapeutic effect of CS-706, a specific cyclooxygenase-2 inhibitor, on gallbladder carcinoma in BK5.ErbB-2 mice. Mol Cancer Ther 6 (2007) 1709-1717
10. Lee D.J., Lyshchik A., Huamani J., Hallahan D.E., and Fleischer A.C. Relationship between retention of a vascular endothelial growth factor receptor 2 (VEGFR2)-targeted ultrasonographic contrast agent and the level of VEGFR2 expression in an in vivo breast cancer model. J Ultrasound Med 27 (2008) 855-866
11. Liu J., Du J., Zhang C., Walker J.W., and Huang X. Progressive troponin I loss impairs cardiac relaxation and causes heart failure in mice. Am J Physiol Heart Circ Physiol 293 (2007) H1273-H1281
12. Lukacs M., Yin J., Pang G., Garcia R.C., Cherin E., Williams R., Mehi J., and Foster F.S. Performance and characterization of new micromachined high-frequency linear arrays. IEEE Trans Ultrason Ferroelectr Freq Control 53 (2006) 1719-1729
13. Olive K.P., and Tuveson D.A. The use of targeted mouse models for preclinical testing of novel cancer therapeutics. Clin Cancer Res 12 (2006) 5277-5287
14. Oralkan O., Ergun A.S., Johnson J.A., Karaman M., Demirci U., Kaviani K., Lee T.H., and Khuri-Yakub B.T. Capacitive micromachined ultrasonic transducers: Next-generation arrays for acoustic imaging?. IEEE Trans Ultrason Ferroelectr Freq Control 49 (2002) 1596-1610
15. Ritter T.A., Shrout T.R., Tutwiler R., and Shung K.K. A 30-MHz piezo-composite ultrasound array for medical imaging applications. IEEE Trans Ultrason Ferroelectr Freq Control 49 (2002) 217-230
16. Ryan L.K., and Foster F.S. Tissue equivalent vessel phantoms for intravascular ultrasound. Ultrasound Med Biol 23 (1997) 261-273
17. Shung K. Diagnostic Ultrasound: Imaging and Blood Flow Measurements (2005), CRC Press, Boca Raton, FL 72-73
18. Trivedi C.M., Luo Y., Yin Z., Zhang M., Zhu W., Wang T., Floss T., Goettlicher M., Noppinger P.R., Wurst W., Ferrari V.A., Abrams C.S., Gruber P.J., and Epstein J.A. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. Nat Med 13 (2007) 324-331
19. Weiss E., Jakob A., Tretbar S., Haberer W., Knoll T., Bauerfeld F., Herrmann J., and Lemor R. Micromachined linear array with 100 MHz center frequency. J Acoust Soc Am 123 (2008) 3784
20. Wirtzfeld L.A., Graham K.C., Groom A.C., Macdonald I.C., Chambers A.F., Fenster A., and Lacefield J.C. Volume measurement variability in three-dimensional high-frequency ultrasound images of murine liver metastases. Phys Med Biol 51 (2006) 2367-2381
21. Wirtzfeld L.A., Wu G., Bygrave M., Yamasaki Y., Sakai H., Moussa M., Izawa J.I., Downey D.B., Greenberg N.M., Fenster A., Xuan J.W., and Lacefield J.C. A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model. Cancer Res 65 (2005) 6337-6345
22. Xu X., Sun L., Cannata J.M., Yen J.T., and Shung K.K. High-frequency ultrasound Doppler system for biomedical applications with a 30-MHz linear array. Ultrasound Med Biol 34 (2008) 638-646
23. Xuan J.W., Bygrave M., Jiang H., Valiyeva F., Dunmore-Buyze J., Holdsworth D.W., Izawa J.I., Bauman G., Moussa M., Winter S.F., Greenberg N.M., Chin J.L., Drangova M., Fenster A., and Lacefield J.C. Functional neoangiogenesis imaging of genetically engineered mouse prostate cancer using three-dimensional power Doppler ultrasound. Cancer Res 67 (2007) 2830-2839
24. Zhou Y.Q., Foster F.S., Nieman B.J., Davidson L., Chen X.J., and Henkelman R.M. Comprehensive transthoracic cardiac imaging in mice using ultrasound biomicroscopy with anatomical confirmation by magnetic resonance imaging. Physiol Genomics 18 (2004) 232-244
25. Zhou Y.Q., Foster F.S., Parkes R., and Adamson S.L. Developmental changes in left and right ventricular diastolic filling patterns in mice. Am J Physiol Heart Circ Physiol 285 (2003) H1563-1575