Potent angiogenic inhibition effects of deacetylated chitohexaose separated from chitooligosaccharides and its mechanism of action in vitro

Carbohydrate Research

Volumn 344, Issue 15, 2009, Pages 1975-1983

  Xiong, Chuannan ^a,c   Wu, Haige ^a,b   Wei, Peng ^a,c   Pan, Ma ^a,c   Tuo, Yaqin ^a   Kusakabe, Isao ^d   Du, Yuguang ^a  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^b DALIAN UNIVERSITY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Angiogenesis; Deacetylated chitohexaose; ECV304; Urokinase plasminogen activator; Vascular endothelial growth factor

Indexed keywords

ANGIOGENESIS; DEACETYLATED CHITOHEXAOSE; ECV304; UROKINASE PLASMINOGEN ACTIVATOR; VASCULAR ENDOTHELIAL GROWTH FACTOR; UROKINASE PLASMINOGEN;

BIOACTIVITY; CHARCOAL; HYDROCHLORIC ACID; PEPTIDES; RESINS; SELF ASSEMBLY; SEPARATION; TUMORS; DIMERS; ENDOTHELIAL CELLS;

ENZYME INHIBITION; CELL ENGINEERING;

ANTINEOPLASTIC AGENT; CHITOOLIGOSACCHARIDE DERIVATIVE; DEACETYLATED CHITOHEXAOSE; GELATINASE B; MESSENGER RNA; OLIGOSACCHARIDE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG; UROKINASE; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CANCER CELL; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; CHITOSAN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GENE EXPRESSION; HUMANS; MATRIX METALLOPROTEINASE 9; MOLECULAR STRUCTURE; NEOVASCULARIZATION, PHYSIOLOGIC; OLIGOSACCHARIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; UROKINASE-TYPE PLASMINOGEN ACTIVATOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 70349176085     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carres.2009.06.036     Document Type: Article

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