Activation of retinal stem cells in the proliferating marginal region of RCS rats during development of retinitis pigmentosa

Neuroscience Letters

Volumn 465, Issue 1, 2009, Pages 41-44

  Jian, Qian ^a   Xu, Haiwei ^a   Xie, Hanping ^a   Tian, Chunyu ^a   Zhao, Tongtao ^a   Yin, ZhengQin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Bromodeoxyuridine; Cell proliferation; Chx 10; Progenitor cells; Retinal degeneration

Indexed keywords

BROXURIDINE; MESSENGER RNA; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL LABELING; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; FEMALE; LONG EVANS RAT; MALE; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA CELL; RETINA DEGENERATION; RETINITIS PIGMENTOSA; SIGNAL TRANSDUCTION; STEM CELL; UPREGULATION;

ADULT STEM CELLS; AGING; ANIMALS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; FEMALE; MALE; RANDOM ALLOCATION; RATS; RATS, LONG-EVANS; RATS, MUTANT STRAINS; RETINA; RETINITIS PIGMENTOSA; STEM CELL NICHE;

EID: 70349119028     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.07.083     Document Type: Article

References (18)

1. Ahmad I., Tang L., and Pham H. Identification of neural progenitors in the adult mammalian eye. Biochem. Biophys. Res. Commun. 270 (2000) 517-521
2. Amato M.A., Arnault E., and Perron M. Retinal stem cells in vertebrates: parallels and divergences. Int. J. Dev. Biol. 48 (2004) 993-1001
3. Chen Z.S., Yin Z.Q., Chen S., and Wang S.J. Electrophysiological changes of retinal ganglion cells in Royal College of Surgeons rats during retinal degeneration. Neuroreport 16 (2005) 971-975
4. Dakubo G.D., Beug S.T., Mazerolle C.J., Thurig S., Wang Y., and Wallace V.A. Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells. Brain Res. 1228 (2008) 27-42
5. Fan X.T., Xu H.W., Cai W.Q., Yang H., and Liu S. Antisense Noggin oligodeoxynucleotide administration decreases cell proliferation in the dentate gyrus of adult rats. Neurosci. Lett. 366 (2004) 107-111
6. Fischer A.J. Neural regeneration in the chick retina. Prog. Retin. Eye Res. 24 (2005) 161-182
7. Fischer A.J., and Reh T.A. Exogenous growth factors stimulate the regeneration of ganglion cells in the chicken retina. Dev. Biol. 251 (2002) 367-379
8. Fischer A.J., and Reh T.A. Identification of a proliferating marginal zone of retinal progenitors in postnatal chickens. Dev. Biol. 220 (2000) 197-210
9. Fischer A.J., and Reh T.A. Transdifferentiation of pigmented epithelial cells: a source of retinal stem cells?. Dev. Neurosci. 23 (2001) 268-276
10. Kubota R., Hokoc J.N., Moshiri A., McGuire C., and Reh T.A. A comparative study of neurogenesis in the retinal ciliary marginal zone of homeothermic vertebrates. Brain Res. Dev. Brain Res. 134 (2002) 31-41
11. Moshiri A., and Reh T.A. Persistent progenitors at the retinal margin of ptc+/- mice. J. Neurosci.: Official J. Soc. Neurosci. 24 (2004) 229-237
12. Reh T.A. Cell-specific regulation of neuronal production in the larval frog retina. J. Neurosci. 7 (1987) 3317-3324
13. Simpson D.A.C., Feeney S., Boyle C., and Stitt A.W. Retinal VEGF mRNA measured by SYBR Green I fluorescence: a versatile approach to quantitative PCR. Mol. Vis. 6 (2000) 178-183
14. Stenkamp D.L., Powers M.K., Carney L.H., and Cameron D.A. Evidence for two distinct mechanisms of neurogenesis and cellular pattern formation in regenerated goldfish retinas. J. Comp. Neurol. 431 (2001) 363-381
15. Tropepe V., Coles B.L., Chiasson B.J., Horsford D.J., Elia A.J., McInnes R.R., and van der Kooy D. Retinal stem cells in the adult mammalian eye. Science 287 (2000) 2032-2036
16. Wan J., Zheng H., Xiao H.L., She Z.J., and Zhou G.M. Sonic hedgehog promotes stem-cell potential of Muller glia in the mammalian retina. Biochem. Biophys. Res. Commun. 363 (2007) 347-354
17. Xu H., Sta Iglesia D.D., Kielczewski J.L., Valenta D.F., Pease M.E., Zack D.J., and Quigley H.A. Characteristics of progenitor cells derived from adult ciliary body in mouse, rat, and human eyes. Invest. Ophthalmol. Vis. Sci. 48 (2007) 1674-1682
18. Young R.W. Cell differentiation in the retina of the mouse. Anat. Rec. 212 (1985) 199-205