Highly efficient and enantioselective biotransformations of racemic azetidine-2-carbonitriles and their synthetic applications

Journal of Organic Chemistry

Volumn 74, Issue 16, 2009, Pages 6077-6082

  Leng, Dong Hui ^a   Wang, De Xiang ^a   Pan, Jie ^a   Huang, Zhi Tang ^a   Wang, Mei Xiang ^a,b  

^a INSTITUTE OF CHEMISTRY   (China)

^b Tsinghua University   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINATION; AMINES; CARBOXYLIC ACIDS; CELL MEMBRANES; CHEMICAL BONDS; CYANIDES; ENANTIOSELECTIVITY; ORGANIC ACIDS;

AMIDASE; AQUEOUS BUFFER; AZETIDINES; BIOCATALYTIC REACTION; CARBONITRILES; CARBOXAMIDES; CHEMICAL EQUATIONS; COMBINED EFFECT; CROSS COUPLING REACTIONS; ENANTIOSELECTIVE; NITRILE HYDRATASES; NUCLEOPHILIC RING-OPENING REACTION; RHODOCOCCUS ERYTHROPOLIS; SYNTHETIC APPLICATION; WHOLE CELL;

AMIDES;

1 BENZYL 2 METHYLAZETIDINE 2 CARBONITRILE; 1 BENZYL 4 METHYLAZETIDINE 2 CARBONITRILE; 1 BENZYLAZETIDINE 2 CARBONITRILE; AMIDASE; AMIDE; AZETIDINE 2 CARBONITRILE; AZETIDINE 2 CARBOXYLIC ACID; AZETIDINE DERIVATIVE; BENZODIAZEPIN 2 ONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CATALYSIS; CHEMICAL REACTION; CHIRALITY; CROSS COUPLING REACTION; ENANTIOSELECTIVITY; NONHUMAN; RACEMIC MIXTURE; RHODOCOCCUS ERYTHROPOLIS; RING OPENING; SYNTHESIS; WHOLE CELL; CHEMISTRY; ENZYME SPECIFICITY; KINETICS; METABOLISM; RHODOCOCCUS; STEREOISOMERISM;

AMIDES; AZETIDINECARBOXYLIC ACID; AZETIDINES; BIOTRANSFORMATION; KINETICS; RHODOCOCCUS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 70349116924     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9011656     Document Type: Article

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