Expression of KiSS-1 gene and its role in invasion and metastasis of human hepatocellular carcinoma

Anatomical Record

Volumn 292, Issue 8, 2009, Pages 1128-1134

  Zang, Shengbing ^a   Liu, Jing Feng ^a   Wang, Bin ^a   Gao, Lingyun ^a   Huang, Aimin ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

KiSS 1; Liver neoplasm; Metastasis; MMP 9; Tissue chip

Indexed keywords

GELATINASE B; METASTIN;

ADULT; ARTICLE; CANCER INVASION; CANCER STAGING; CELL INVASION; CELL MOTILITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE FUNCTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CELL CARCINOMA; LIVER METASTASIS; LIVER RESECTION; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN TARGETING; UPREGULATION;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; GENE EXPRESSION; HUMANS; LIVER NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM STAGING; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 70349083392     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.20950     Document Type: Article

References (19)

1. Dhar DK, Naora H, Kubota H, Maruyama R, Yoshimura H, Tonomoto Y, Tachibana M, Ono T, Otani H, Nagasue N. 2004. Down-regulation of KiSS-1 expression is responsible for tumor invasion and worse prognosis in gastric carcinoma. Int J Cancer 111: 868-872.
2. Freije JM, Balbín M, Pendás AM, Sánchez LM, Puente XS, López-Otín C. 2003. Matrix metalloproteinases and tumor progression. Adv Exp Med Biol 532:91-107.
3. Giannelli G, Pierri F, Trerotoli P, Marinosci F, Serio G, Schiraldi O, Antonaci S. 2002. Occurrence of portal vein tumor thrombus in hepatocellular carcinoma affects prognosis and survival. A retrospective clinical study of 150 cases. Hepatol Res 24:50-59.
4. Harms JF, Welch DR, Miele ME. 2003. KiSS1 metastasis suppression and emergent pathways. Clin Exp Metastasis 20:11-18.
5. Hou YK, Wang Y, Cong WM, Wu MC. 2007. Expression of tumor metastasis-suppressor gene KiSS-1 and matrix metalloproteinase-9 in portal vein tumor thrombus of hepatocellular carcinoma. Chin J Cancer (Chin) 26:591-595.
6. Ikeguchi M, Hirooka Y, Kaibara N. 2003. Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in hepatocellular carcinoma. J Cancer Res Clin Oncol 129:531-535.
7. Ikeguchi M, Yamaguchi K, Kaibara N. 2004. Clinical significance of the loss of KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in esophageal squamous cell carcinoma. Clin Cancer Res 10:1379-1383.
8. Ishii Y, Nakasato Y, Kobayashi S, Yamazaki Y, Aoki T. 2003. A study on angiogenesis-related matrix metalloproteinase networks in primary hepatocellular carcinoma. J Exp Clin Cancer Res 22: 461-470.
9. Kew MC. 2002. Epidemiology of hepatocellular carcinoma. Toxicology 181:35-38.
10. Kononen J, Bubendorf L, Kallioniemi A, Bärlund M, Schraml P, Leighton S, Torhorst J, Mihatsch MJ, Sauter G, Kallioniemi OP. 1998. Tissue microarrays for high-throughput molecular profiling: of tumor specimens. Nat Med 4:844-847.
11. Kotani M, Detheux M, Vandenbogaerde A, Communi D, Vanderwinden JM, Poul EL, Brezillon S, Tyldesley R, Suarez-Huerta R, Vandeput F, Blanpain C, Schiffmann N, Vassart G, Parmentier M. 2001. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem 276:34631-34636.
12. Lee JH, Miele ME, Hicks D, Phillips KK, Trent JM, Weissman BE, Welch DR. 1996. KiSS-1, a novel human malignant melanoma metastasis-suppressor gene. J Natl Cancer Inst 88:1731-1737.
13. Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC. 2001. AXOR12,a novel human G protein coupled receptor, activated by the peptide KiSS-1. J Biol Chem 276:28969-28975.
14. Nakashima O, Kojiro M. 2001. Recurrence of hepatocellular carcinoma: multicentric occurrence or intrahepatic metastasis? A viewpoint in terms of pathology. J Hepatobiliary Pancreat Surg 8: 404-409.
15. Ohtaki T, Shintani Y, Honda S, Matsumoto H, Hori A, Kanehashi K, Terao Y, Kumano S, Takatsu Y, Masuda Y, Ishibashi Y, Watanabe T, Asada M, Yamada T, Suenaga M, Kitada C, Usuki S, Kurokawa T, Onda H, Nishimura O, Fujino M. 2001. Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature 411:613-617.
16. Schmid K, Wang X, Haitel A, Sieghart W, Peck-Radosavljevic M, Bodingbauer M, Rasoul-Rockenschaub S, Wrba F. 2007. KiSS-1 overexpression as an independent prognostic marker in hepatocellular carcinoma: an immunohistochemical study. Virchows Arch 450:143-149.
17. Stark AM, Tongers K, Maass N, Mehdorn HM, Held-Feindt J. 2005. Reduced metastasis-suppressor gene mRNA-expression in breast cancer brain metastases[J]. J Cancer Res Clin Oncol 131:191-198.
18. Yan C, Wang H, Boyd DD. 2001. KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation[J]. J Biol Chem 276:1164-1172.
19. Zang SB, Huang AM, Gao LY, Liu JF, Gao MQ. 2007. Modified protocol for preparing paraffin tissue microarrays and for hepatocellular carcinoma study. J Histochem Cytochem (Chin) 16: 251-253.