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Volumn , Issue 1, 2009, Pages

First line chemotherapy in low risk gestational trophoblastic neoplasia

Author keywords

Antineoplastic agents *administration dosage; adverse effects ; Case control studies; Cohort studies; Dactinomycin *administration dosage; adverse effects ; Drug administration schedule; Female; Gestational trophoblastic neoplasms *drug therapy ; Humans; Leucovorin administration dosage ; Methotrexate *administration dosage; Adverse effects ; Pregnancy; Randomized controlled trials as topic; Risk; Vitamin B complex administration dosage

Indexed keywords

DACTINOMYCIN; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; METHOTREXATE;

EID: 70249148550     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD007102.pub2     Document Type: Review
Times cited : (51)

References (49)
  • 1
    • 37449033851 scopus 로고    scopus 로고
    • Treatment for low-risk gestational trophoblastic disease: Comparison of single-agent methotrexate, dactinomycin and combination regimens
    • Abrao RA, de Andrade JM, Tiezzi DG, Marana HR, Candido dos Reis FJ, Clagnan WS. Treatment for low-risk gestational trophoblastic disease: comparison of single-agent methotrexate, dactinomycin and combination regimens. Gynecologic Oncology 2008; Vol.108, issue 1:149-153
    • (2008) Gynecologic Oncology , vol.108 , Issue.1 , pp. 149-153
    • Abrao, R.A.1    De Andrade, J.M.2    Tiezzi, D.G.3    Marana, H.R.4    Candido Dos Reis, F.J.5    Clagnan, W.S.6
  • 2
    • 17244374396 scopus 로고    scopus 로고
    • Comparison of pulse methotrexate and pulse dactinomycin in the treatment of low-risk gestational trophoblastic neoplasia
    • DOI 10.1111/j.1479-828X.2005.00366.x
    • Gilani MM, Yarandi F, Eftekhar Z, Hanjani P. Comparison of pulse methotrexate and pulse dactinomycin in the treatment of low-risk gestational trophoblastic neoplasia. Australian and New Zealand Journal of Obstetrics andGynaecology 2005; Vol.45, issue 2:161-164 (Pubitemid 40528565)
    • (2005) Australian and New Zealand Journal of Obstetrics and Gynaecology , vol.45 , Issue.2 , pp. 161-164
    • Gilani, M.M.1    Yarandi, F.2    Eftekhar, Z.3    Hanjani, P.4
  • 3
    • 0030039169 scopus 로고    scopus 로고
    • Decision making for chemotherapy administration in patients with low risk gestational trophoblastic neoplasia
    • Kohorn EI. Decision making for chemotherapy administration in patients with low risk gestational trophoblastic neoplasia. Interna- tional Journal of Gynecological Cancer 1996;6:279-285
    • (1996) Interna- Tional Journal of Gynecological Cancer , vol.6 , pp. 279-285
    • Kohorn, E.I.1
  • 5
    • 60749085865 scopus 로고    scopus 로고
    • A randomized phase III trial comparing weekly parenteral methotrexate and "pulsed" dactinomycin as primary management for low-risk gestational trophoblastic neoplasia: A Gynecologic Oncology Group study
    • Osborne R, Filiaci V, Schink J, Mannel R, Provencher D, Alvarez-Secord A, et al. A randomized phase III trial comparing weekly parenteral methotrexate and "pulsed" dactinomycin as primary management for low-risk gestational trophoblastic neoplasia: A Gynecologic Oncology Group study. Gynecologic Oncology. 2008; Vol.108: S2-S31.
    • (2008) Gynecologic Oncology , vol.108
    • Osborne, R.1    Filiaci, V.2    Schink, J.3    Mannel, R.4    Provencher, D.5    Alvarez-Secord, A.6
  • 6
    • 0019988601 scopus 로고
    • Treatment of nonmetastatic gestational trophoblastic disease: Results of methotrexate alone versus methotrexate--folinic acid
    • Smith EB, Weed JC, Jr, Tyrey L, Hammond CB. Treatment of nonmetastatic gestational trophoblastic disease: results of methotrexate alone versus methotrexate--folinic acid. American Journal of Obstetrics and Gynecology 1982;144(1):88-92.
    • (1982) American Journal of Obstetrics and Gynecology , vol.144 , Issue.1 , pp. 88-92
    • Smith, E.B.1    Weed Jr., J.C.2    Tyrey, L.3    Hammond, C.B.4
  • 7
    • 0021804159 scopus 로고
    • Methotrexate with citrovorum factor rescue in gestational trophoblastic disease
    • Wong LC, Choo YC, Ma HK. Methotrexate with citrovorum factor rescue in gestational trophoblastic disease. American Journal of Obstetrics and Gynecology 1985; Vol.152, issue 1:59-62. (Pubitemid 15039809)
    • (1985) American Journal of Obstetrics and Gynecology , vol.152 , Issue.1 , pp. 59-62
    • Wong, L.C.1    Choo, Y.C.2    Ma, H.K.3
  • 9
    • 0018669351 scopus 로고
    • Methotrexate with citrovorum factor rescue for nonmetastatic gestational trophoblastic neoplasms
    • Berkowitz RS, Goldstein DP. Methotrexate with citrovorum factor rescue for nonmetastatic gestational trophoblastic neoplasms. Obstetrics and Gynecology 1979; Vol.54, issue 6:725-728 (Pubitemid 10241097)
    • (1979) Obstetrics and Gynecology , vol.54 , Issue.6 , pp. 725-728
    • Berkowitz, R.S.1    Goldstein, D.P.2
  • 11
    • 0031879053 scopus 로고    scopus 로고
    • Comparison of chemotherapies with methotrexate, VP-16 and actinomycin-D in low-risk gestational trophoblastic disease. Remission rates and drug toxicities
    • Matsui H, Iitsuka Y, Seki K, Sekiya S. Comparison of chemotherapies with methotrexate, VP-16 and actinomycin-D in low-risk gestational trophoblastic disease. Remission rates and drug toxicities. Gynecologic and Obstetric Investigation 1998; Vol.46, issue 1:5-8.
    • (1998) Gynecologic and Obstetric Investigation , vol.46 , Issue.1 , pp. 5-8
    • Matsui, H.1    Iitsuka, Y.2    Seki, K.3    Sekiya, S.4
  • 12
    • 13844280396 scopus 로고    scopus 로고
    • Relapse rate of patients with low-risk gestational trophoblastic tumor initially treated with single-agent chemotherapy
    • DOI 10.1016/j.ygyno.2004.11.011
    • Matsui H, Suzuka K, Yamazawa K, Tanaka N,Mitsuhashi A, Seki K, et al.Relapse rate of patients with low-risk gestational trophoblastic tumour initially treated with single-agent chemotherapy. Gynecologic Oncology 2005; Vol.96, issue 3:616-620 (Pubitemid 40255478)
    • (2005) Gynecologic Oncology , vol.96 , Issue.3 , pp. 616-620
    • Matsui, H.1    Suzuka, K.2    Yamazawa, K.3    Tanaka, N.4    Mitsuhashi, A.5    Seki, K.6    Sekiya, S.7
  • 13
    • 0018840956 scopus 로고
    • Actinomycin D toxicity in the treatment of trophoblastic disease
    • Petrilli ES, Morrow CP. Actinomycin D toxicity in the treatment of trophoblastic disease. Gynecologic Oncology 1980;9:18-22.
    • (1980) Gynecologic Oncology , vol.9 , pp. 18-22
    • Petrilli, E.S.1    Morrow, C.P.2
  • 14
    • 0029885043 scopus 로고    scopus 로고
    • Treatment of low-risk metastatic gestational trophoblastic tumors with single-agent chemotherapy
    • Roberts JP, Lurain JR. Treatment of low-risk metastatic gestational trophoblastic tumors with single-agent chemotherapy. American Journal of Obstetrics and Gynecology 1996; Vol.174, issue 6:1917-1923
    • (1996) American Journal of Obstetrics and Gynecology , vol.174 , Issue.6 , pp. 1917-1923
    • Roberts, J.P.1    Lurain, J.R.2
  • 15
    • 0026703648 scopus 로고
    • Remission rates and significance of prognostic factors in gestational trophoblastic tumors
    • Ayhan A, Yaper EG, Deren O, Kisnisci H. Remission rates and significance of prognostic factors in gestational trophoblastic tumors. Journal of Reproductive Medicine 1992;37(5):461-465
    • (1992) Journal of Reproductive Medicine , vol.37 , Issue.5 , pp. 461-465
    • Ayhan, A.1    Yaper, E.G.2    Deren, O.3    Kisnisci, H.4
  • 16
    • 0017138758 scopus 로고
    • Risk and prognostic factors in trophoblastic neoplasia
    • Bagshawe KD. Risk and prognostic factors in trophoblastic neoplasia. Cancer 1976;38(3):1373-1385
    • (1976) Cancer , vol.38 , Issue.3 , pp. 1373-1385
    • Bagshawe, K.D.1
  • 18
    • 33749004802 scopus 로고    scopus 로고
    • Phase II trial of pulse dactinomycin as salvage therapy for failed low-risk gestational trophoblastic neoplasia
    • Covens A, Fialici VL, Burger RA, Osborne R, Chen MD. Phase II trial of pulse dactinomycin as salvage therapy for failed low-risk gestational trophoblastic neoplasia. Cancer 2006;107(6):1280-1286
    • (2006) Cancer , vol.107 , Issue.6 , pp. 1280-1286
    • Covens, A.1    Fialici, V.L.2    Burger, R.A.3    Osborne, R.4    Chen, M.D.5
  • 20
    • 0001910889 scopus 로고    scopus 로고
    • Statisticalmethods for examining heterogeneity and combining results fromseveral studies inmetaanalysis
    • Egger M, Davey Smith G, Altman DG (eds). London: BMJ Publication Group
    • Deeks JJ, Altman DG, Bradburn MJ. Statisticalmethods for examining heterogeneity and combining results fromseveral studies inmetaanalysis. In: Egger M, Davey Smith G, Altman DG (eds). Systematic Reviews in Health Care: Meta-Analysis in Context (2nd edition). London: BMJ Publication Group, 2001.
    • (2001) Systematic Reviews in Health Care: Meta-Analysis in Context (2nd Edition)
    • Deeks, J.J.1    Altman, D.G.2    Bradburn, M.J.3
  • 26
    • 85100415918 scopus 로고    scopus 로고
    • Higgins JPT, Green S, editors. [updated Febuary 2008]. The Cochrane Collaboration Available from
    • Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions 5.0.0 [updated Febuary 2008]. The Cochrane Collaboration, 2008. Available from www.cochrane-handbook.org.
    • (2008) Cochrane Handbook for Systematic Reviews of Interventions 5.0.0
  • 29
    • 0025648720 scopus 로고
    • Rapid escalation of weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease: A Gynecologic Oncology Group study
    • Homesley HD, Blessing JA, Schlaerth J, Rettenmaier M, Major FJ. Rapid escalation of weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease: a Gynecologic Oncology Group study. Gynecologic Oncology 1990;39(3):305-308
    • (1990) Gynecologic Oncology , vol.39 , Issue.3 , pp. 305-308
    • Homesley, H.D.1    Blessing, J.A.2    Schlaerth, J.3    Rettenmaier, M.4    Major, F.J.5
  • 30
    • 0028265659 scopus 로고
    • Development of single-agent chemotherapy regimens for gestational trophoblastic disease
    • Homesley HD. Development of single-agent chemotherapy regimens for gestational trophoblastic disease. Journal of Reproductive Medicine 1994;39(3):185-192
    • (1994) Journal of Reproductive Medicine , vol.39 , Issue.3 , pp. 185-192
    • Homesley, H.D.1
  • 31
    • 0842265590 scopus 로고    scopus 로고
    • Low-risk persistent gestational trophoblastic disease treated with low-dose methotrexate: Efficacy, acute and long-term effects
    • DOI 10.1038/sj.bjc.6601422
    • Khan F, Everard J, Ahmed S, Coleman RE, Aitkin M, Hancock BW. Low-risk persistent trophoblastic disease treated with low-dose methotrexate: efficacy, acute and long term effects. British Journal of Cancer 2003;89(12):2197-2201 (Pubitemid 38167999)
    • (2003) British Journal of Cancer , vol.89 , Issue.12 , pp. 2197-2201
    • Khan, F.1    Everard, J.2    Ahmed, S.3    Coleman, R.E.4    Aitken, M.5    Hancock, B.W.6
  • 32
    • 0034009883 scopus 로고    scopus 로고
    • Combining the staging system of the International Federation of Gynecology and Obstetrics with the scoring system of the World Heath Organization for trophoblastic neoplasia. Report of the working committee of the International Society for the Study of Trophoblastic Disease and the International Gynecologic Cancer Society
    • DOI 10.1046/j.1525-1438.2000.00002.x
    • Kohorn EI, Goldstein DP, Hancock BW, Kim SJ, Lurain JR, Newlands E, et al.Combining the staging systemof the International Federation of Gynecology and Obstetrics with the scoring system of the World Health Organization for trophoblastic neoplasia. Report of the Working Committeeo the International Society for the Study of Trophoblastic Disease and International Gynecologic Cancer Society. International Journal of Gynecological Cancer 2000;10:84-88 (Pubitemid 30219484)
    • (2000) International Journal of Gynecological Cancer , vol.10 , Issue.1 , pp. 84-88
    • Kohorn, E.I.1    Goldstein, D.P.2    Hancock, B.W.3    Kim, S.J.4    Luraini, J.R.5    Newlands, E.6    Soper, J.T.7    Wong, L.C.8
  • 33
    • 0036534303 scopus 로고    scopus 로고
    • Low-risk persistent gestational trophoblastic disease: Outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000
    • McNeish IA, Strickland S, Holden L, Rustin GJ, Foskett M, Seckl MJ, et al.Low-risk persistent gestational trophoblastic disease: outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000. Journal of Clinical Oncology 2002;20(7): 1838-1844
    • (2002) Journal of Clinical Oncology , vol.20 , Issue.7 , pp. 1838-1844
    • McNeish, I.A.1    Strickland, S.2    Holden, L.3    Rustin, G.J.4    Foskett, M.5    Seckl, M.J.6
  • 34
    • 51549121915 scopus 로고    scopus 로고
    • The FIGO staging for gestational trophoblastic neoplasia 2000, FIGO Committee Report
    • Nagan HY. The FIGO staging for gestational trophoblastic neoplasia 2000, FIGO Committee Report. International Journal of Gynecology and Obstetrics 2002;77:285-287
    • (2002) International Journal of Gynecology and Obstetrics , vol.77 , pp. 285-287
    • Nagan, H.Y.1
  • 35
    • 0016751276 scopus 로고
    • Actinomycin D as the primary agent for gestational trophoblastic disease
    • Osathanondh R, Goldstein DP, Pastorfide GB. Actinomycin D as the primary agent for gestational trophoblastic disease. Cancer 1975; 36(3):863-866
    • (1975) Cancer , vol.36 , Issue.3 , pp. 863-866
    • Osathanondh, R.1    Goldstein, D.P.2    Pastorfide, G.B.3
  • 36
    • 0023193279 scopus 로고
    • Single-dose Actinomycin-D treatment for nonmetastatic gestational trophoblastic disease. a prospective phase II trial of the Gynecologic Ongology Group
    • DOI 10.1002/1097-0142(19871101)60:9<2173::AID-CNCR2820600910>3.0. CO;2-3
    • Petrilli ES, Twiggs LB, Blessing JA, Teng NH, Curry S. Single-dose actinomycin-Dtreatment for nonmetastatic gestational trophoblastic disease. A prospective phase II trial of the Gynecologic Oncology Group. Cancer 1987;60(9):2173-2176 (Pubitemid 17153478)
    • (1987) Cancer , vol.60 , Issue.9 , pp. 2173-2176
    • Petrilli, E.S.1    Twiggs, L.B.2    Blessing, J.A.3    Teng, N.N.H.4    Curry, S.5
  • 37
    • 0029885043 scopus 로고    scopus 로고
    • Treatment of low-risk metastatic gestational trophoblastic tumors with single-agent chemotherapy
    • Roberts JP, Lurain JR. Treatment of low-risk metastatic gestational trophoblastic tumors with single-agent chemotherapy. American Journal of Obstetrics and Gynaecology 1996;174(6):1917-1923
    • (1996) American Journal of Obstetrics and Gynaecology , vol.174 , Issue.6 , pp. 1917-1923
    • Roberts, J.P.1    Lurain, J.R.2
  • 38
    • 0024353711 scopus 로고
    • Alternating methotrexate and dactinomycin in nonmetastatic gestational trophoblastic disease
    • Rose PG, Piver MS. Alternating methotrexate and dactinomycin in nonmetastatic gestational trophoblastic disease. Journal of Surgical Oncology 1989;41(3):148-152 (Pubitemid 19190388)
    • (1989) Journal of Surgical Oncology , vol.41 , Issue.3 , pp. 148-152
    • Rose, P.G.1    Piver, M.S.2
  • 39
    • 0021186081 scopus 로고
    • Single-dose actinomycin D in the treatment of postmolar trophoblastic disease
    • Schlaerth JB, Morrow CP, Nalick RH, Gaddis O, Jr. Single-dose actinomycin D in the treatment of postmolar trophoblastic disease. Gyncologic Oncology 1984;19(1):53-56 (Pubitemid 14027477)
    • (1984) Gynecologic Oncology , vol.19 , Issue.1 , pp. 53-56
    • Schlaerth, J.B.1    Morrow, C.P.2    Nalick, R.H.3    Gaddis Jr., O.4
  • 41
    • 0141806311 scopus 로고    scopus 로고
    • Epidemiology
    • Hancock BW, Newlands ES, Berkwitz RS, Cole LA editor(s). Internationa Society for the Study of Trophoblastic Diseases
    • Smith HO, Kim SJ. Epidemiology. In: Hancock BW, Newlands ES, Berkwitz RS, Cole LA editor(s). Gestational Trophoblastic Diseases. 2nd Edition. Internationa Society for the Study of Trophoblastic Diseases, 2003:39-76.
    • (2003) Gestational Trophoblastic Diseases. 2nd Edition , pp. 39-76
    • Smith, H.O.1    Kim, S.J.2
  • 43
    • 0034770609 scopus 로고    scopus 로고
    • Successful treatment of a persistent mole with myometrial invasion by direct injection of methotrexate
    • Su WH, Wang PH, Chang SP. Successful treatment of a persistent mole with myometrial invasion by direct injection of methotrexate. European Journal of Gynaecological Oncology 2001;22(4):283-286
    • (2001) European Journal of Gynaecological Oncology , vol.22 , Issue.4 , pp. 283-286
    • Su, W.H.1    Wang, P.H.2    Chang, S.P.3
  • 44
    • 0021155216 scopus 로고
    • Re-evaluation of 5-fluorouracil as a single agent for gestational malignant trophoblastic neoplasms
    • Sung HC, Wu PC, Wang YB. Re-evaluation of 5-fluorouracil as a single agent for gestational malignant trophoblastic neoplasms. Advances in Experimental Medicine and Biology 1984;176:355-367
    • (1984) Advances in Experimental Medicine and Biology , vol.176 , pp. 355-367
    • Sung, H.C.1    Wu, P.C.2    Wang, Y.B.3
  • 45
    • 0020629589 scopus 로고
    • Pulse actinomycin D scheduling in nonmetastatic gestational trophoblastic neoplasia: Cost-effective chemotherapy
    • Twiggs LB. Pulse actinomycin D scheduling in nonmetastatic gestational trophoblastic neoplasia: cost-effective chemotherapy. Gynecologic Oncology 1983;16(2):190-195
    • (1983) Gynecologic Oncology , vol.16 , Issue.2 , pp. 190-195
    • Twiggs, L.B.1
  • 46
    • 0032408523 scopus 로고    scopus 로고
    • Chemotherapy using 5-fluorouracil and nitrocaphanum in malignant trophoblastic tumor
    • DOI 10.1006/gyno.1998.5196
    • Wang Y, Jiu L, Guan Y, Qiu D. Chemotherapy using 5-fluorouracil and nitrocaphanum in malignant trophoblastic tumor. Gynecologic Oncology 1998;71(3):416-419 (Pubitemid 29022329)
    • (1998) Gynecologic Oncology , vol.71 , Issue.3 , pp. 416-419
    • Wang, Y.1    Jiu, L.2    Guan, Y.3    Qiu, D.4
  • 47
    • 0003635670 scopus 로고
    • Gestatational trophoblastic diseases
    • WHO
    • WHO. Gestatational trophoblastic diseases. WHO Technical report Sens 692 1983.
    • (1983) WHO Technical Report Sens 692
  • 48
    • 0021273891 scopus 로고
    • Oral etoposide in gestational trophoblastic disease
    • Wong LC, Choo YC, Ma HK. Oral etoposide in gestational trophoblastic disease. Cancer Treatment Reports 1984;68(5):775-777 (Pubitemid 14115205)
    • (1984) Cancer Treatment Reports , vol.68 , Issue.5 , pp. 775-777
    • Wong, L.C.1    Choo, Y.C.2    Ma, H.K.3
  • 49
    • 0022591778 scopus 로고
    • Primary oral etoposide therapy in gestational trophoblastic disease: An update
    • Wong LC, Choo YC, Ma HK. Primary oral etoposide therapy in gestational trophoblastic disease. An update. Cancer 1986;58(1): 14-17 (Pubitemid 16093096)
    • (1986) Cancer , vol.58 , Issue.1 , pp. 14-17
    • Wong, L.C.1    Choo, Y.C.2    Facog, S.3    Ma, H.K.4


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