-
1
-
-
0000549763
-
Mechanics of bile secretion; effect of perfusion pressure and temperature on bile flow and bile secretion pressure
-
Brauer R.W., Leong G.F., and Holloway R.J. Mechanics of bile secretion; effect of perfusion pressure and temperature on bile flow and bile secretion pressure. Am J Physiol 177 (1954) 103-112
-
(1954)
Am J Physiol
, vol.177
, pp. 103-112
-
-
Brauer, R.W.1
Leong, G.F.2
Holloway, R.J.3
-
2
-
-
0001584473
-
Secretion of organic anions in the formation of urine and bile
-
Sperber I. Secretion of organic anions in the formation of urine and bile. Pharmacol Rev 11 (1959) 109-134
-
(1959)
Pharmacol Rev
, vol.11
, pp. 109-134
-
-
Sperber, I.1
-
3
-
-
0013909738
-
Role of bile ducts during secretin choleresis in dogs
-
Wheeler H.O., and Mancusi-Ungaro P.L. Role of bile ducts during secretin choleresis in dogs. Am J Physiol 210 (1966) 1153-1159
-
(1966)
Am J Physiol
, vol.210
, pp. 1153-1159
-
-
Wheeler, H.O.1
Mancusi-Ungaro, P.L.2
-
4
-
-
0015951831
-
Mechanisms and control of secretion of bile water and electrolytes
-
Erlinger S., and Dhumeaux D. Mechanisms and control of secretion of bile water and electrolytes. Gastroenterology 66 (1974) 281-304
-
(1974)
Gastroenterology
, vol.66
, pp. 281-304
-
-
Erlinger, S.1
Dhumeaux, D.2
-
5
-
-
0018793186
-
Biochemical evidence that Na+, K+-ATPase is located at the lateral region of the hepatocyte surface membrane
-
Poupon R.E., and Evans W.H. Biochemical evidence that Na+, K+-ATPase is located at the lateral region of the hepatocyte surface membrane. FEBS Lett 108 (1979) 374-378
-
(1979)
FEBS Lett
, vol.108
, pp. 374-378
-
-
Poupon, R.E.1
Evans, W.H.2
-
6
-
-
0025991571
-
Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system
-
Nishida T., Gatmaitan Z., Che M., and Arias I.M. Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system. Proc Natl Acad Sci U S A 88 (1991) 6590-6594
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 6590-6594
-
-
Nishida, T.1
Gatmaitan, Z.2
Che, M.3
Arias, I.M.4
-
7
-
-
0025721848
-
Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system
-
Hagenbuch B., Stieger B., Foguet M., Lubbert H., and Meier P.J. Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system. Proc Natl Acad Sci U S A 88 (1991) 10629-10633
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 10629-10633
-
-
Hagenbuch, B.1
Stieger, B.2
Foguet, M.3
Lubbert, H.4
Meier, P.J.5
-
8
-
-
0028850221
-
The role of mdr2 P-glycoprotein in biliary lipid secretion. Cross-talk between cancer research and biliary physiology
-
Oude Elferink R.P., and Groen A.K. The role of mdr2 P-glycoprotein in biliary lipid secretion. Cross-talk between cancer research and biliary physiology. J Hepatol 23 (1995) 617-625
-
(1995)
J Hepatol
, vol.23
, pp. 617-625
-
-
Oude Elferink, R.P.1
Groen, A.K.2
-
9
-
-
0023125182
-
Is ursodeoxycholic acid an effective treatment for primary biliary cirrhosis?
-
Poupon R., Chrétien Y., Poupon R.E., Ballet F., Calmus Y., and Darnis F. Is ursodeoxycholic acid an effective treatment for primary biliary cirrhosis?. Lancet 1 (1987) 834-836
-
(1987)
Lancet
, vol.1
, pp. 834-836
-
-
Poupon, R.1
Chrétien, Y.2
Poupon, R.E.3
Ballet, F.4
Calmus, Y.5
Darnis, F.6
-
10
-
-
0025876404
-
A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis
-
UDCA-PBC Study Group
-
Poupon R.E., Balkau B., Eschwege E., Poupon R., and UDCA-PBC Study Group. A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. N Engl J Med 324 (1991) 1548-1554
-
(1991)
N Engl J Med
, vol.324
, pp. 1548-1554
-
-
Poupon, R.E.1
Balkau, B.2
Eschwege, E.3
Poupon, R.4
-
11
-
-
17344366172
-
A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis
-
Strautnieks S.S., Bull L.N., Knisely A.S., Kocoshis S.A., Dahl N., Arnell H., et al. A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis. Nat Genet 20 (1998) 233-238
-
(1998)
Nat Genet
, vol.20
, pp. 233-238
-
-
Strautnieks, S.S.1
Bull, L.N.2
Knisely, A.S.3
Kocoshis, S.A.4
Dahl, N.5
Arnell, H.6
-
12
-
-
0031907132
-
A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis
-
Bull L.N., van Eijk M.J., Pawlikowska L., DeYoung J.A., Juijn J.A., Liao M., et al. A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis. Nat Genet 18 (1998) 219-224
-
(1998)
Nat Genet
, vol.18
, pp. 219-224
-
-
Bull, L.N.1
van Eijk, M.J.2
Pawlikowska, L.3
DeYoung, J.A.4
Juijn, J.A.5
Liao, M.6
-
13
-
-
0040284751
-
Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis
-
de Vree J.M., Jacquemin E., Sturm E., Cresteil D., Bosma P.J., Aten J., et al. Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis. Proc Natl Acad Sci U S A 95 (1998) 282-287
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 282-287
-
-
de Vree, J.M.1
Jacquemin, E.2
Sturm, E.3
Cresteil, D.4
Bosma, P.J.5
Aten, J.6
-
14
-
-
0033591297
-
Identification of a nuclear receptor for bile acids
-
Makishima M., Okamoto A.Y., Repa J.J., Tu H., Learned R.M., Luk A., et al. Identification of a nuclear receptor for bile acids. Science 284 (1999) 1362-1365
-
(1999)
Science
, vol.284
, pp. 1362-1365
-
-
Makishima, M.1
Okamoto, A.Y.2
Repa, J.J.3
Tu, H.4
Learned, R.M.5
Luk, A.6
-
15
-
-
0033591387
-
Bile acids: natural ligands for an orphan nuclear receptor
-
Parks D.J., Blanchard S.G., Bledsoe R.K., Chandra G., Consler T.G., Kliewer S.A., et al. Bile acids: natural ligands for an orphan nuclear receptor. Science 284 (1999) 1365-1368
-
(1999)
Science
, vol.284
, pp. 1365-1368
-
-
Parks, D.J.1
Blanchard, S.G.2
Bledsoe, R.K.3
Chandra, G.4
Consler, T.G.5
Kliewer, S.A.6
-
16
-
-
0033026760
-
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
-
Wang H., Chen J., Hollister K., Sowers L.C., and Forman B.M. Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol Cell 3 (1999) 543-553
-
(1999)
Mol Cell
, vol.3
, pp. 543-553
-
-
Wang, H.1
Chen, J.2
Hollister, K.3
Sowers, L.C.4
Forman, B.M.5
-
17
-
-
33748940093
-
The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo
-
Rizzo G., Disante M., Mencarelli A., Renga B., Gioiello A., Pellicciari R., et al. The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo. Mol Pharmacol 70 (2006) 1164-1173
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1164-1173
-
-
Rizzo, G.1
Disante, M.2
Mencarelli, A.3
Renga, B.4
Gioiello, A.5
Pellicciari, R.6
-
19
-
-
33644859036
-
Hepatocanalicular transport defects: pathophysiologic mechanisms of rare diseases
-
Oude Elferink R.P., Paulusma C.C., and Groen A.K. Hepatocanalicular transport defects: pathophysiologic mechanisms of rare diseases. Gastroenterology 130 (2006) 908-925
-
(2006)
Gastroenterology
, vol.130
, pp. 908-925
-
-
Oude Elferink, R.P.1
Paulusma, C.C.2
Groen, A.K.3
-
20
-
-
0036623233
-
Nuclear receptor regulation of hepatic function
-
Karpen S.J. Nuclear receptor regulation of hepatic function. J Hepatol 36 (2002) 832-850
-
(2002)
J Hepatol
, vol.36
, pp. 832-850
-
-
Karpen, S.J.1
-
21
-
-
0035813186
-
Nuclear receptor minireview series
-
Olefsky J.M. Nuclear receptor minireview series. J Biol Chem 276 (2001) 36863-36864
-
(2001)
J Biol Chem
, vol.276
, pp. 36863-36864
-
-
Olefsky, J.M.1
-
22
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
-
Sinal C.J., Tohkin M., Miyata M., Ward J.M., Lambert G., and Gonzalez F.J. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102 (2000) 731-744
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.J.1
Tohkin, M.2
Miyata, M.3
Ward, J.M.4
Lambert, G.5
Gonzalez, F.J.6
-
23
-
-
33745471487
-
FXR: a target for cholestatic syndromes?
-
Cai S.Y., and Boyer J.L. FXR: a target for cholestatic syndromes?. Expert Opin Ther Targets 10 (2006) 409-421
-
(2006)
Expert Opin Ther Targets
, vol.10
, pp. 409-421
-
-
Cai, S.Y.1
Boyer, J.L.2
-
24
-
-
27844546989
-
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
-
Inagaki T., Choi M., Moschetta A., Peng L., Cummins C.L., McDonald J.G., et al. Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab 2 (2005) 217-225
-
(2005)
Cell Metab
, vol.2
, pp. 217-225
-
-
Inagaki, T.1
Choi, M.2
Moschetta, A.3
Peng, L.4
Cummins, C.L.5
McDonald, J.G.6
-
25
-
-
56149085041
-
X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response
-
Wang Y.D., Chen W.D., Wang M., Yu D., Forman B.M., Huang W., et al. X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response. Hepatology 48 (2008) 1632-1643
-
(2008)
Hepatology
, vol.48
, pp. 1632-1643
-
-
Wang, Y.D.1
Chen, W.D.2
Wang, M.3
Yu, D.4
Forman, B.M.5
Huang, W.6
-
26
-
-
33847044019
-
Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor
-
Yang F., Huang X., Yi T., Yen Y., Moore D.D., and Huang W. Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor. Cancer Res 67 (2007) 863-867
-
(2007)
Cancer Res
, vol.67
, pp. 863-867
-
-
Yang, F.1
Huang, X.2
Yi, T.3
Yen, Y.4
Moore, D.D.5
Huang, W.6
-
27
-
-
57149118460
-
Nuclear bile acid receptor FXR protects against intestinal tumorigenesis
-
Modica S., Murzilli S., Salvatore L., Schmidt D.R., and Moschetta A. Nuclear bile acid receptor FXR protects against intestinal tumorigenesis. Cancer Res 68 (2008) 9589-9594
-
(2008)
Cancer Res
, vol.68
, pp. 9589-9594
-
-
Modica, S.1
Murzilli, S.2
Salvatore, L.3
Schmidt, D.R.4
Moschetta, A.5
-
28
-
-
0035853057
-
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
-
Xie W., Radominska-Pandya A., Shi Y., Simon C.M., Nelson M.C., Ong E.S., et al. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci U S A 98 (2001) 3375-3380
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 3375-3380
-
-
Xie, W.1
Radominska-Pandya, A.2
Shi, Y.3
Simon, C.M.4
Nelson, M.C.5
Ong, E.S.6
-
29
-
-
0035853165
-
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
-
Staudinger J.L., Goodwin B., Jones S.A., Hawkins-Brown D., MacKenzie K.I., LaTour A., et al. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc Natl Acad Sci U S A 98 (2001) 3369-3374
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 3369-3374
-
-
Staudinger, J.L.1
Goodwin, B.2
Jones, S.A.3
Hawkins-Brown, D.4
MacKenzie, K.I.5
LaTour, A.6
-
30
-
-
0036209248
-
Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor
-
Kliewer S.A., and Willson T.M. Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor. J Lipid Res 43 (2002) 359-364
-
(2002)
J Lipid Res
, vol.43
, pp. 359-364
-
-
Kliewer, S.A.1
Willson, T.M.2
-
31
-
-
0037386735
-
Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor
-
Xie W., Yeuh M.F., Radominska-Pandya A., Saini S.P., Negishi Y., Bottroff B.S., et al. Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor. Proc Natl Acad Sci U S A 100 (2003) 4150-4155
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4150-4155
-
-
Xie, W.1
Yeuh, M.F.2
Radominska-Pandya, A.3
Saini, S.P.4
Negishi, Y.5
Bottroff, B.S.6
-
32
-
-
0034687397
-
The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism
-
Wei P., Zhang J., Egan-Hafley M., Liang S., and Moore D.D. The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature 407 (2000) 920-923
-
(2000)
Nature
, vol.407
, pp. 920-923
-
-
Wei, P.1
Zhang, J.2
Egan-Hafley, M.3
Liang, S.4
Moore, D.D.5
-
33
-
-
0037389946
-
Induction of bilirubin clearance by the constitutive androstane receptor (CAR)
-
Huang W., Zhang J., Chua S.S., Qatanani M., Han Y., Granata R., et al. Induction of bilirubin clearance by the constitutive androstane receptor (CAR). Proc Natl Acad Sci U S A 100 (2003) 4156-4161
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4156-4161
-
-
Huang, W.1
Zhang, J.2
Chua, S.S.3
Qatanani, M.4
Han, Y.5
Granata, R.6
-
34
-
-
0037064177
-
Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR
-
Zhang J., Huang W., Chua S.S., Wei P., and Moore D.D. Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR. Science 298 (2002) 422-424
-
(2002)
Science
, vol.298
, pp. 422-424
-
-
Zhang, J.1
Huang, W.2
Chua, S.S.3
Wei, P.4
Moore, D.D.5
-
35
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
-
Peet D.J., Turley S.D., Ma W., Janowski B.A., Lobaccaro J.M., Hammer R.E., et al. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 93 (1998) 693-704
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.M.5
Hammer, R.E.6
-
36
-
-
0036851863
-
The liver X receptor gene team: potential new players in atherosclerosis
-
Repa J.J., and Mangelsdorf D.J. The liver X receptor gene team: potential new players in atherosclerosis. Nat Med 8 (2002) 1243-1248
-
(2002)
Nat Med
, vol.8
, pp. 1243-1248
-
-
Repa, J.J.1
Mangelsdorf, D.J.2
-
37
-
-
0035914330
-
27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells
-
Fu X., Menke J.G., Chen Y., Zhou G., MacNaul K.L., Wright S.D., et al. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J Biol Chem 276 (2001) 38378-38387
-
(2001)
J Biol Chem
, vol.276
, pp. 38378-38387
-
-
Fu, X.1
Menke, J.G.2
Chen, Y.3
Zhou, G.4
MacNaul, K.L.5
Wright, S.D.6
-
38
-
-
0033854882
-
Selective activation of liver X receptor alpha by 6alpha-hydroxy bile acids and analogs
-
Song C., Hiipakka R.A., and Liao S. Selective activation of liver X receptor alpha by 6alpha-hydroxy bile acids and analogs. Steroids 65 (2000) 423-427
-
(2000)
Steroids
, vol.65
, pp. 423-427
-
-
Song, C.1
Hiipakka, R.A.2
Liao, S.3
-
39
-
-
30144431977
-
Vitamin D receptor regulation of the steroid/bile acid sulfotransferase SULT2A1
-
Chatterjee B., Echchgadda I., and Song C.S. Vitamin D receptor regulation of the steroid/bile acid sulfotransferase SULT2A1. Methods Enzymol 400 (2005) 165-191
-
(2005)
Methods Enzymol
, vol.400
, pp. 165-191
-
-
Chatterjee, B.1
Echchgadda, I.2
Song, C.S.3
-
40
-
-
59649116947
-
Vitamin D3 Modulates the Expression of Bile Acid Regulatory Genes and Represses Inflammation in Bile Duct-Ligated Mice
-
Ogura M., Nishida S., Ishizawa M., Sakurai K., Shimizu M., Matsuo S., et al. Vitamin D3 Modulates the Expression of Bile Acid Regulatory Genes and Represses Inflammation in Bile Duct-Ligated Mice. J Pharmacol Exp Ther 328 (2009) 564-570
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 564-570
-
-
Ogura, M.1
Nishida, S.2
Ishizawa, M.3
Sakurai, K.4
Shimizu, M.5
Matsuo, S.6
-
41
-
-
43549092632
-
Vitamin D and innate immunity
-
Hewison M. Vitamin D and innate immunity. Curr Opin Investig Drugs 9 (2008) 485-490
-
(2008)
Curr Opin Investig Drugs
, vol.9
, pp. 485-490
-
-
Hewison, M.1
-
42
-
-
62949244071
-
Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium
-
d'Aldebert E., Biyeyeme Bi Mve M.-J., Mergey M., Wendum D., Firrincieli D., Coilly A., et al. Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium. Gastroenterology 136 (2009) 1435-1443
-
(2009)
Gastroenterology
, vol.136
, pp. 1435-1443
-
-
d'Aldebert, E.1
Biyeyeme Bi Mve, M.-J.2
Mergey, M.3
Wendum, D.4
Firrincieli, D.5
Coilly, A.6
-
43
-
-
0032806949
-
Genetic basis of progressive familial intrahepatic cholestasis
-
Jacquemin E., and Hadchouel M. Genetic basis of progressive familial intrahepatic cholestasis. J Hepatol 31 (1999) 377-381
-
(1999)
J Hepatol
, vol.31
, pp. 377-381
-
-
Jacquemin, E.1
Hadchouel, M.2
-
44
-
-
0033916586
-
The molecular genetics of familial intrahepatic cholestasis
-
Jansen P.L., and Muller M. The molecular genetics of familial intrahepatic cholestasis. Gut 47 (2000) 1-5
-
(2000)
Gut
, vol.47
, pp. 1-5
-
-
Jansen, P.L.1
Muller, M.2
-
45
-
-
21844436858
-
Enterohepatic transport of bile salts and genetics of cholestasis
-
Pauli-Magnus C., Stieger B., Meier Y., Kullak-Ublick G.A., and Meier P.J. Enterohepatic transport of bile salts and genetics of cholestasis. J Hepatol 43 (2005) 342-357
-
(2005)
J Hepatol
, vol.43
, pp. 342-357
-
-
Pauli-Magnus, C.1
Stieger, B.2
Meier, Y.3
Kullak-Ublick, G.A.4
Meier, P.J.5
-
46
-
-
0035053975
-
MDR3 gene defect in adults with symptomatic intrahepatic and gallbladder cholesterol cholelithiasis
-
Rosmorduc O., Hermelin B., and Poupon R. MDR3 gene defect in adults with symptomatic intrahepatic and gallbladder cholesterol cholelithiasis. Gastroenterology 120 (2001) 1459-1467
-
(2001)
Gastroenterology
, vol.120
, pp. 1459-1467
-
-
Rosmorduc, O.1
Hermelin, B.2
Poupon, R.3
-
47
-
-
3242727039
-
Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
-
Fickert P., Fuchsbichler A., Wagner M., Zollner G., Kaser A., Tilg H., et al. Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 127 (2004) 261-274
-
(2004)
Gastroenterology
, vol.127
, pp. 261-274
-
-
Fickert, P.1
Fuchsbichler, A.2
Wagner, M.3
Zollner, G.4
Kaser, A.5
Tilg, H.6
-
48
-
-
1442355466
-
Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis
-
Lammert F., Wang D.Q., Hillebrandt S., Geier A., Fickert P., Trauner M., et al. Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis. Hepatology 39 (2004) 117-128
-
(2004)
Hepatology
, vol.39
, pp. 117-128
-
-
Lammert, F.1
Wang, D.Q.2
Hillebrandt, S.3
Geier, A.4
Fickert, P.5
Trauner, M.6
-
49
-
-
1642290033
-
Intrahepatic cholestasis of pregnancy
-
Riely C.A., and Bacq Y. Intrahepatic cholestasis of pregnancy. Clin Liver Dis 8 (2004) 167-176
-
(2004)
Clin Liver Dis
, vol.8
, pp. 167-176
-
-
Riely, C.A.1
Bacq, Y.2
-
50
-
-
20844451597
-
Intrahepatic cholestasis of pregnancy: from bedside to bench to bedside
-
Poupon R. Intrahepatic cholestasis of pregnancy: from bedside to bench to bedside. Liver Int 25 (2005) 467-468
-
(2005)
Liver Int
, vol.25
, pp. 467-468
-
-
Poupon, R.1
-
51
-
-
0014899033
-
Steroid sulphates in plasma from pregnant women with pruritus and elevated plasma bile acid levels
-
Sjovall J., and Sjovall K. Steroid sulphates in plasma from pregnant women with pruritus and elevated plasma bile acid levels. Ann Clin Res 2 (1970) 321-337
-
(1970)
Ann Clin Res
, vol.2
, pp. 321-337
-
-
Sjovall, J.1
Sjovall, K.2
-
52
-
-
0030759322
-
Profiles of bile acids and progesterone metabolites in the urine and serum of women with intrahepatic cholestasis of pregnancy
-
Meng L.J., Reyes H., Palma J., Hernandez I., Ribalta J., and Sjovall J. Profiles of bile acids and progesterone metabolites in the urine and serum of women with intrahepatic cholestasis of pregnancy. J Hepatol 27 (1997) 346-357
-
(1997)
J Hepatol
, vol.27
, pp. 346-357
-
-
Meng, L.J.1
Reyes, H.2
Palma, J.3
Hernandez, I.4
Ribalta, J.5
Sjovall, J.6
-
53
-
-
33847064667
-
MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes
-
Trauner M., Fickert P., and Wagner M. MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes. Semin Liver Dis 27 (2007) 77-98
-
(2007)
Semin Liver Dis
, vol.27
, pp. 77-98
-
-
Trauner, M.1
Fickert, P.2
Wagner, M.3
-
54
-
-
33746537974
-
Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy
-
Keitel V., Vogt C., Haussinger D., and Kubitz R. Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy. Gastroenterology 131 (2006) 624-629
-
(2006)
Gastroenterology
, vol.131
, pp. 624-629
-
-
Keitel, V.1
Vogt, C.2
Haussinger, D.3
Kubitz, R.4
-
55
-
-
21144447029
-
ATP8B1 mutations in British cases with intrahepatic cholestasis of pregnancy
-
Mullenbach R., Bennett A., Tetlow N., Patel N., Hamilton G., Cheng F., et al. ATP8B1 mutations in British cases with intrahepatic cholestasis of pregnancy. Gut 54 (2005) 829-834
-
(2005)
Gut
, vol.54
, pp. 829-834
-
-
Mullenbach, R.1
Bennett, A.2
Tetlow, N.3
Patel, N.4
Hamilton, G.5
Cheng, F.6
-
56
-
-
36549054059
-
Association of the multidrug-resistance-associated protein gene (ABCC2) variants with intrahepatic cholestasis of pregnancy
-
Sookoian S., Castano G., Burgueno A., Gianotti T.F., and Pirola C.J. Association of the multidrug-resistance-associated protein gene (ABCC2) variants with intrahepatic cholestasis of pregnancy. J Hepatol 48 (2008) 125-132
-
(2008)
J Hepatol
, vol.48
, pp. 125-132
-
-
Sookoian, S.1
Castano, G.2
Burgueno, A.3
Gianotti, T.F.4
Pirola, C.J.5
-
57
-
-
34547515667
-
Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy
-
Van Mil S.W., Milona A., Dixon P.H., Mullenbach R., Geenes V.L., Chambers J., et al. Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy. Gastroenterology 133 (2007) 507-516
-
(2007)
Gastroenterology
, vol.133
, pp. 507-516
-
-
Van Mil, S.W.1
Milona, A.2
Dixon, P.H.3
Mullenbach, R.4
Geenes, V.L.5
Chambers, J.6
-
59
-
-
0037370065
-
Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes
-
Spirli C., Fabris L., Duner E., Fiorotto R., Ballardini G., Roskams T., et al. Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes. Gastroenterology 124 (2003) 737-753
-
(2003)
Gastroenterology
, vol.124
, pp. 737-753
-
-
Spirli, C.1
Fabris, L.2
Duner, E.3
Fiorotto, R.4
Ballardini, G.5
Roskams, T.6
-
60
-
-
18544371193
-
Defective regulation of cholangiocyte Cl-/HCO3(-) and Na+/H+ exchanger activities in primary biliary cirrhosis
-
Melero S., Spirli C., Zsembery A., Medina J.F., Joplin R.E., Duner E., et al. Defective regulation of cholangiocyte Cl-/HCO3(-) and Na+/H+ exchanger activities in primary biliary cirrhosis. Hepatology 35 (2002) 1513-1521
-
(2002)
Hepatology
, vol.35
, pp. 1513-1521
-
-
Melero, S.1
Spirli, C.2
Zsembery, A.3
Medina, J.F.4
Joplin, R.E.5
Duner, E.6
-
61
-
-
38849104576
-
Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells
-
Arenas F., Hervias I., Uriz M., Joplin R., Prieto J., and Medina J.F. Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells. J Clin Invest 118 (2008) 695-709
-
(2008)
J Clin Invest
, vol.118
, pp. 695-709
-
-
Arenas, F.1
Hervias, I.2
Uriz, M.3
Joplin, R.4
Prieto, J.5
Medina, J.F.6
-
62
-
-
0033033458
-
Assessment of biliary bicarbonate secretion in humans by positron emission tomography
-
Prieto J., Garcia N., Marti-Climent J.M., Penuelas I., Richter J.A., and Medina J.F. Assessment of biliary bicarbonate secretion in humans by positron emission tomography. Gastroenterology 117 (1999) 167-172
-
(1999)
Gastroenterology
, vol.117
, pp. 167-172
-
-
Prieto, J.1
Garcia, N.2
Marti-Climent, J.M.3
Penuelas, I.4
Richter, J.A.5
Medina, J.F.6
-
63
-
-
0013138711
-
Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis
-
Zollner G., Fickert P., Silbert D., Fuchsbichler A., Marschall H.U., Zatloukal K., et al. Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis. J Hepatol 38 (2003) 717-727
-
(2003)
J Hepatol
, vol.38
, pp. 717-727
-
-
Zollner, G.1
Fickert, P.2
Silbert, D.3
Fuchsbichler, A.4
Marschall, H.U.5
Zatloukal, K.6
-
64
-
-
55549146529
-
Genetic factors of susceptibility and of severity in primary biliary cirrhosis
-
Poupon R., Ping C., Chrétien Y., Corpechot C., Chazouillères O., Simon T., et al. Genetic factors of susceptibility and of severity in primary biliary cirrhosis. J Hepatol 49 (2008) 1038-1045
-
(2008)
J Hepatol
, vol.49
, pp. 1038-1045
-
-
Poupon, R.1
Ping, C.2
Chrétien, Y.3
Corpechot, C.4
Chazouillères, O.5
Simon, T.6
-
65
-
-
43049094474
-
Ae2a,b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis
-
Salas J.T., Banales J.M., Sarvide S., Recalde S., Ferrer A., Uriarte I., et al. Ae2a,b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis. Gastroenterology 134 (2008) 1482-1493
-
(2008)
Gastroenterology
, vol.134
, pp. 1482-1493
-
-
Salas, J.T.1
Banales, J.M.2
Sarvide, S.3
Recalde, S.4
Ferrer, A.5
Uriarte, I.6
-
66
-
-
1542619640
-
BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis
-
Pauli-Magnus C., Kerb R., Fattinger K., Lang T., Anwald B., Kullak-Ublick G.A., et al. BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis. Hepatology 39 (2004) 779-791
-
(2004)
Hepatology
, vol.39
, pp. 779-791
-
-
Pauli-Magnus, C.1
Kerb, R.2
Fattinger, K.3
Lang, T.4
Anwald, B.5
Kullak-Ublick, G.A.6
-
67
-
-
11144357062
-
ABCB4 gene mutations and primary sclerosing cholangitis
-
Rosmorduc O., Hermelin B., Boelle P.Y., Poupon R.E., Poupon R., and Chazouillères O. ABCB4 gene mutations and primary sclerosing cholangitis. Gastroenterology 126 (2004) 1220-1222
-
(2004)
Gastroenterology
, vol.126
, pp. 1220-1222
-
-
Rosmorduc, O.1
Hermelin, B.2
Boelle, P.Y.3
Poupon, R.E.4
Poupon, R.5
Chazouillères, O.6
-
68
-
-
38549176268
-
Variation in the mdr3 gene influences disease progression in psc patients and disease susceptibility in epistatic interaction with a polymorphism in the ost-α gene
-
Melum E., Boberg K.M., Franke A., Bergquist A., Hampe J., Schreiber S., et al. Variation in the mdr3 gene influences disease progression in psc patients and disease susceptibility in epistatic interaction with a polymorphism in the ost-α gene. Hepatology 46 (2007) 265A
-
(2007)
Hepatology
, vol.46
-
-
Melum, E.1
Boberg, K.M.2
Franke, A.3
Bergquist, A.4
Hampe, J.5
Schreiber, S.6
-
69
-
-
56949083881
-
Cystic fibrosis transmembrane conductance regulator gene polymorphisms in patients with primary sclerosing cholangitis
-
Henckaerts L., Jaspers M., Van Steenbergen W., Vliegen L., Fevery J., Nuytten H., et al. Cystic fibrosis transmembrane conductance regulator gene polymorphisms in patients with primary sclerosing cholangitis. J Hepatol 50 (2009) 150-157
-
(2009)
J Hepatol
, vol.50
, pp. 150-157
-
-
Henckaerts, L.1
Jaspers, M.2
Van Steenbergen, W.3
Vliegen, L.4
Fevery, J.5
Nuytten, H.6
-
70
-
-
3242737526
-
Induction of colitis in cftr-/- mice results in bile duct injury
-
Blanco P.G., Zaman M.M., Junaidi O., Sheth S., Yantiss R.K., Nasser I.A., et al. Induction of colitis in cftr-/- mice results in bile duct injury. Am J Physiol Gastrointest Liver Physiol 287 (2004) G491-G496
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Blanco, P.G.1
Zaman, M.M.2
Junaidi, O.3
Sheth, S.4
Yantiss, R.K.5
Nasser, I.A.6
-
71
-
-
33748113966
-
Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis
-
Karlsen T.H., Lie B.A., Frey Froslie K., Thorsby E., Broome U., Schrumpf E., et al. Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis. Gastroenterology 131 (2006) 781-787
-
(2006)
Gastroenterology
, vol.131
, pp. 781-787
-
-
Karlsen, T.H.1
Lie, B.A.2
Frey Froslie, K.3
Thorsby, E.4
Broome, U.5
Schrumpf, E.6
-
72
-
-
0036725044
-
Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited
-
Paumgartner G., and Beuers U. Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited. Hepatology 36 (2002) 525-531
-
(2002)
Hepatology
, vol.36
, pp. 525-531
-
-
Paumgartner, G.1
Beuers, U.2
-
73
-
-
0032525819
-
A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation
-
Rodrigues C.M., Fan G., Ma X., Kren B.T., and Steer C.J. A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation. J Clin Invest 101 (1998) 2790-2799
-
(1998)
J Clin Invest
, vol.101
, pp. 2790-2799
-
-
Rodrigues, C.M.1
Fan, G.2
Ma, X.3
Kren, B.T.4
Steer, C.J.5
-
74
-
-
0034910937
-
Tauroursodesoxycholate-induced choleresis involves p38 (MAPK) activation and translocation of the bile salt export pump in rats
-
Kurz A.K., Graf D., Schmitt M., Vom Dahl S., and Haussinger D. Tauroursodesoxycholate-induced choleresis involves p38 (MAPK) activation and translocation of the bile salt export pump in rats. Gastroenterology 121 (2001) 407-419
-
(2001)
Gastroenterology
, vol.121
, pp. 407-419
-
-
Kurz, A.K.1
Graf, D.2
Schmitt, M.3
Vom Dahl, S.4
Haussinger, D.5
-
75
-
-
32044467118
-
24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
-
Fickert P., Wagner M., Marschall H.U., Fuchsbichler A., Zollner G., Tsybrovskyy O., et al. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 130 (2006) 465-481
-
(2006)
Gastroenterology
, vol.130
, pp. 465-481
-
-
Fickert, P.1
Wagner, M.2
Marschall, H.U.3
Fuchsbichler, A.4
Zollner, G.5
Tsybrovskyy, O.6
-
76
-
-
39849106455
-
New insights on the molecular and cell biology of human cholangiopathies
-
Alvaro D., and Mancino M.G. New insights on the molecular and cell biology of human cholangiopathies. Mol Aspects Med 29 (2008) 50-57
-
(2008)
Mol Aspects Med
, vol.29
, pp. 50-57
-
-
Alvaro, D.1
Mancino, M.G.2
|