Protective effect of total aralosides of Aralia elata (Miq) Seem (TASAES) against diabetic cardiomyopathy in rats during the early stage, and possible mechanisms

Experimental and Molecular Medicine

Volumn 41, Issue 8, 2009, Pages 538-547

  Xi, Shugang ^a   Zhou, Guihua ^b   Zhang, Xuexin ^a   Zhang, Wenjie ^a   Cai, Lu ^a,b   Zhao, Chunyan ^a  

^a JILIN UNIVERSITY   (China)

^b University of Louisville School of Medicine   (United States)

Author keywords

Araloside; Calcium channels, L type; Cardiomyopathies; Connective tissue growth factor; Diabetes mellitus; Heart; Hemodynamics; Myocardium

Indexed keywords

CALCIUM CHANNEL L TYPE; CONNECTIVE TISSUE GROWTH FACTOR; GLUCOSE; HERBACEOUS AGENT; POTASSIUM CHANNEL; TOTAL ARALOSIDE OF ARALIA ELATA SEEM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARALIA; ARALIA ELATA; ARTICLE; BODY WEIGHT; CARDIOMYOPATHY; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; ELECTRON MICROSCOPE; GLUCOSE BLOOD LEVEL; HEART FUNCTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HEMODYNAMIC MONITORING; HISTOLOGY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LOW DRUG DOSE; MALE; NONHUMAN; PATCH CLAMP; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; SYSTOLIC BLOOD PRESSURE; TREATMENT DURATION; UPREGULATION; WISTAR RAT;

ARALIA CHINENSIS; ARALIA ELATA; RATTUS;

ANIMALS; ARALIA; CALCIUM CHANNELS, L-TYPE; CARDIOMYOPATHIES; CONNECTIVE TISSUE GROWTH FACTOR; DIABETES MELLITUS, EXPERIMENTAL; DRUGS, CHINESE HERBAL; HEART; HEMODYNAMICS; MALE; MYOCARDIUM; OLEANOLIC ACID; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; RATS; RATS, WISTAR; SAPONINS; TREATMENT OUTCOME;

EID: 70249103802     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2009.41.8.059     Document Type: Article

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