Neuropsychological performance in patients with POLG1 mutations and the syndrome of mitochondrial spinocerebellar ataxia and epilepsy

Epilepsy and Behavior

Volumn 16, Issue 1, 2009, Pages 172-174

  Gramstad, Arne ^a,b   Bindoff, Laurence A ^a,b   Lillebø, Atle ^a   Tzoulis, Charalampos ^a,b   Engelsen, Bernt A ^a,b  

^a HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

Cognition; Halstead Reitan Battery; IQ; Lateralization; Mitochondrial disease; Neurogenetics; Occipital lobe; Wechsler Adult Intelligence Scale; Wechsler Memory Scale Revised

Indexed keywords

GENE PRODUCT; POLYMERASE GAMMA 1; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; COGNITIVE DEFECT; EPILEPTIC STATE; FEMALE; HUMAN; INTELLIGENCE QUOTIENT; MALE; MEMORY DISORDER; MITOCHONDRIAL SPINOCEREBELLAR ATAXIA AND EPILEPSY; MUTATIONAL ANALYSIS; NEUROLOGIC DISEASE; NEUROPSYCHOLOGICAL TEST; WECHSLER INTELLIGENCE SCALE;

ADOLESCENT; ADULT; DNA-DIRECTED DNA POLYMERASE; EPILEPSY; EXECUTIVE FUNCTION; FEMALE; HUMANS; INTELLIGENCE TESTS; MALE; MEMORY; MUTATION; NEUROPSYCHOLOGICAL TESTS; SPINOCEREBELLAR ATAXIAS; YOUNG ADULT;

EID: 70249099594     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2009.01.014     Document Type: Article

References (14)

1. Tzoulis C., Engelsen B.A., Telstad W., et al. The spectrum of clinical disease caused by the A467T and W748S POLG mutations: a study of 26 cases. Brain 129 (2006) 1685-1692
2. Engelsen B.A., Tzoulis C., Karlsen B., et al. POLG1 mutations cause a syndromic epilepsy with occipital lobe predilection. Brain 131 (2008) 818-828
3. Wechsler D. Manual for the Wechsler Adult Intelligence Scale. New York: The Psychological Corporation;1955.
4. Matarazzo J.D. Wechsler's measurement and appraisal of adult intelligence. 5th ed. (1972), Oxford University Press, New York
5. Warrington E.K., James M., and Maciejewski C. The WAIS as a lateralizing and localizing diagnostic instrument: a study of 656 patients with unilateral cerebral lesions. Neuropsychologia 24 (1986) 223-239
6. Iverson G.L., Mendrek A., and Adams R.L. The persistent belief that VIQ-PIQ splits suggest lateralized brain damage. Appl Neuropsychol 11 (2004) 85-90
7. Reitan R.M., and Wolfson D. The Halstead-Reitan neuropsychological test battery. Theory and clinical applications. 2nd ed. (1993), Neuropsychology Press, Tucson, AZ
8. Wechsler D. Wechsler Adult Intelligence Scale: manual. 3rd ed. (1997), The Psychological Corporation, San Antonio
9. Wechsler D. Wechsler memory scale-revised: manual (1987), The Psychological Corporation, San Antonio
10. Kløve H. Validation studies in adult clinical neuropsychology. In: Reitan R.M., and Davison L.A. (Eds). Clinical neuropsychology: current status and applications (1974), Hemisphere Publishing Corporation, Washington, DC 211-235
11. Sherer M., and Adams R.L. Cross-validation of Reitan and Wolfson's neuropsychological deficit scales. Arch Clin Neuropsychol 8 (1993) 429-435
12. Gramstad A., Engelsen B.A., and Hugdahl K. Dichotic listening with forced attention in patients with temporal lobe epilepsy: significance of left hemisphere cognitive dysfunction. Scand J Psychol 47 (2006) 163-170
13. Aarli JA, Engelsen BA. Occipital lobe epilepsies. In: Vinken PJ, Bruyn GW, Meinardi H, editors. Handbook of clinical neurology, revised series 29. The epilepsies, Part II. Amsterdam: Elsevier Science; 2000. p. 107-15.
14. Luerding R., Boesebeck F., and Ebner A. Cognitive changes after epilepsy surgery in the posterior cortex. J Neurol Neurosurg Psychiatry 75 (2004) 583-587