메뉴 건너뛰기




Volumn 182, Issue 10, 2009, Pages 6187-6194

Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; HEMATOPOIETIC CELL KINASE; HEMATOPOIETIC PROGENITOR KINASE 1; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 70149122305     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802631     Document Type: Article
Times cited : (52)

References (43)
  • 1
    • 0037645137 scopus 로고    scopus 로고
    • Functional modulation of dendritic cells to suppress adaptive immune responses
    • DOI 10.1189/jlb.0902431
    • Woltman, A. M., and C. van Kooten. 2003. Functional modulation of dendritic cells to suppress adaptive immune responses. J. Leukocyte Biol. 73: 428-441. (Pubitemid 38040088)
    • (2003) Journal of Leukocyte Biology , vol.731 , Issue.4 , pp. 428-441
    • Woltman, A.M.1    Van Kooten, C.2
  • 2
    • 33847183077 scopus 로고    scopus 로고
    • Cooperation of Toll-like receptor signals in innate immune defence
    • DOI 10.1038/nri2038, PII NRI2038
    • Trinchieri, G., and A. Sher. 2007. Cooperation of Toll-like receptor signals in innate immune defence. Nat. Rev. Immunol. 7: 179-190. (Pubitemid 46310482)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.3 , pp. 179-190
    • Trinchieri, G.1    Sher, A.2
  • 3
    • 34247280027 scopus 로고    scopus 로고
    • CC chemokines and protective immunity: Insights gained from mother-to-child transmission of HIV
    • Tiemessen, C. T., and L. Kuhn. 2007. CC chemokines and protective immunity: insights gained from mother-to-child transmission of HIV. Nat. Immunol. 8: 219-222.
    • (2007) Nat. Immunol. , vol.8 , pp. 219-222
    • Tiemessen, C.T.1    Kuhn, L.2
  • 4
    • 2942679279 scopus 로고    scopus 로고
    • A Bcl-2-dependent molecular timer regulates the lifespan and immunogenicity of dendritic cells
    • Hou, W. S., and L. Van Parijs. 2004. A Bcl-2-dependent molecular timer regulates the lifespan and immunogenicity of dendritic cells. Nat. Immunol. 5: 583-589.
    • (2004) Nat. Immunol. , vol.5 , pp. 583-589
    • Hou, W.S.1    Van Parijs, L.2
  • 5
    • 33845709678 scopus 로고    scopus 로고
    • An essential role for Akt1 in dendritic cell function and tumor immunotherapy
    • DOI 10.1038/nbt1262, PII NBT1262
    • Park, D., N. Lapteva, M. Seethammagari, K. M. Slawin, and D. M. Spencer. 2006. An essential role for Akt1 in dendritic cell function and tumor immunotherapy. Nat. Biotechnol. 24: 1581-1590. (Pubitemid 44967484)
    • (2006) Nature Biotechnology , vol.24 , Issue.12 , pp. 1581-1590
    • Park, D.1    Lapteva, N.2    Seethammagari, M.3    Slawin, K.M.4    Spencer, D.M.5
  • 6
    • 33750286563 scopus 로고    scopus 로고
    • CD4 T cell-induced, bid-dependent apoptosis of cutaneous dendritic cells regulates T cell expansion and immune responses
    • Pradhan, S., J. Genebriera, W. L. Denning, K. Felix, C. A. Elmets, and L. Timares. 2006. CD4 T cell-induced, Bid-dependent apoptosis of cutaneous dendritic cells regulates T cell expansion and immune responses. J. Immunol. 177: 5956-5967. (Pubitemid 44628809)
    • (2006) Journal of Immunology , vol.177 , Issue.9 , pp. 5956-5967
    • Pradhan, S.1    Genebriera, J.2    Denning, W.L.3    Felix, K.4    Elmets, C.A.5    Timares, L.6
  • 8
    • 0037032835 scopus 로고    scopus 로고
    • The protein kinase complement of the human genome
    • DOI 10.1126/science.1075762
    • Manning, G., D. B. Whyte, R. Martinez, T. Hunter, and S. Sudarsanam. 2002. The protein kinase complement of the human genome. Science 298: 1912-1934. (Pubitemid 35425239)
    • (2002) Science , vol.298 , Issue.5600 , pp. 1912-1934
    • Manning, G.1    Whyte, D.B.2    Martinez, R.3    Hunter, T.4    Sudarsanam, S.5
  • 9
    • 0029763450 scopus 로고    scopus 로고
    • Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/ SAPK kinase cascade
    • Hu, M. C., W. R. Qiu, X. Wang, C. F. Meyer, and T. H. Tan. 1996. Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/ SAPK kinase cascade. Genes Dev. 10: 2251-2264.
    • (1996) Genes Dev. , vol.10 , pp. 2251-2264
    • Hu, M.C.1    Qiu, W.R.2    Wang, X.3    Meyer, C.F.4    Tan, T.H.5
  • 11
    • 33846969931 scopus 로고    scopus 로고
    • Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses
    • Shui, J. W., J. S. Boomer, J. Han, J. Xu, G. A. Dement, G. Zhou, and T. H. Tan. 2007. Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses. Nat. Immunol. 8: 84-91.
    • (2007) Nat. Immunol. , vol.8 , pp. 84-91
    • Shui, J.W.1    Boomer, J.S.2    Han, J.3    Xu, J.4    Dement, G.A.5    Zhou, G.6    Tan, T.H.7
  • 12
    • 0035805496 scopus 로고    scopus 로고
    • Caspase-mediated Cleavage of Hematopoietic Progenitor Kinase 1 (HPK1) Converts an Activator of NFκB into an Inhibitor of NFκB
    • DOI 10.1074/jbc.M008343200
    • Arnold, R., J. Liou, H. C. Drexler, A. Weiss, and F. Kiefer. 2001. Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFκB into an inhibitor of NFκB. J. Biol. Chem. 276: 14675-14684. (Pubitemid 37373340)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.18 , pp. 14675-14684
    • Arnold, R.1    Liou, J.2    Drexler, H.C.A.3    Weiss, A.4    Kiefer, F.5
  • 13
    • 2442461214 scopus 로고    scopus 로고
    • Recruitment of the Actin-binding Protein HIP-55 to the Immunological Synapse Regulates T Cell Receptor Signaling and Endocytosis
    • DOI 10.1074/jbc.M312659200
    • Le Bras, S., I. Foucault, A. Foussat, C. Brignone, O. Acuto, and M. Deckert. 2004. Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis. J. Biol. Chem. 279: 15550-15560. (Pubitemid 38618956)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.15 , pp. 15550-15560
    • Le Bras, S.1    Foucault, I.2    Foussat, A.3    Brignone, C.4    Acuto, O.5    Deckert, M.6
  • 14
    • 0035976905 scopus 로고    scopus 로고
    • Hematopoietic Progenitor Kinase 1 Associates Physically and Functionally with the Adaptor Proteins B Cell Linker Protein and SLP-76 in Lymphocytes
    • DOI 10.1074/jbc.M106811200
    • Sauer, K., J. Liou, S. B. Singh, D. Yablonski, A. Weiss, and R. M. Perlmutter. 2001. Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes. J. Biol. Chem. 276: 45207-45216. (Pubitemid 37391315)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.48 , pp. 45207-45216
    • Sauer, K.1    Liou, J.2    Singh, S.B.3    Yablonski, D.4    Weiss, A.5    Perlmutter, R.M.6
  • 15
    • 0038542822 scopus 로고    scopus 로고
    • 2-induced fos gene transcription
    • DOI 10.1182/blood-2002-07-2316
    • Sawasdikosol, S., K. M. Russo, and S. J. Burakoff. 2003. Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription. Blood 101: 3687-3689. (Pubitemid 36857960)
    • (2003) Blood , vol.101 , Issue.9 , pp. 3687-3689
    • Sawasdikosol, S.1    Russo, K.M.2    Burakoff, S.J.3
  • 17
    • 0033531954 scopus 로고    scopus 로고
    • Hematopoietic progenitor kinase 1 is a component of transforming growth factor β-induced c-Jun N-terminal kinase signaling cascade
    • Zhou, G., S. C. Lee, Z. Yao, and T. H. Tan. 1999. Hematopoietic progenitor kinase 1 is a component of transforming growth factor β-induced c-Jun N-terminal kinase signaling cascade. J. Biol. Chem. 274: 13133-13138. (Pubitemid 129518515)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.19 , pp. 13133-13138
    • Zhou, G.1    Lee, S.C.2    Yao, Z.3    Tan, T.-H.4
  • 18
    • 0030836865 scopus 로고    scopus 로고
    • SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1
    • DOI 10.1074/jbc.272.44.27804
    • Anafi, M., F. Kiefer, G. D. Gish, G. Mbamalu, N. N. Iscove, and T. Pawson. 1997. SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1. J. Biol. Chem. 272: 27804-27811. (Pubitemid 27473580)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.44 , pp. 27804-27811
    • Anafi, M.1    Kiefer, F.2    Gish, G.D.3    Mbamalu, G.4    Iscove, N.N.5    Pawson, T.6
  • 19
    • 0033562824 scopus 로고    scopus 로고
    • Activation of hematopoietic progenitor kinase-1 by erythropoietin
    • Nagata, Y., F. Kiefer, T. Watanabe, and K. Todokoro. 1999. Activation of hematopoietic progenitor kinase-1 by erythropoietin. Blood 93: 3347-3354. (Pubitemid 29220902)
    • (1999) Blood , vol.93 , Issue.10 , pp. 3347-3354
    • Nagata, Y.1    Kiefer, F.2    Watanabe, T.3    Todokoro, K.4
  • 20
    • 0031569223 scopus 로고    scopus 로고
    • Bacterial Lipopolysaccharide Stimulates the Production of Cytokines and the Expression of Costimulatory Molecules by Human Peripheral Blood Dendritic Cells Evidence for a Soluble CD14-Dependent Pathway
    • Verhasselt, V., C. Buelens, F. Willems, D. De Groote, N. Haeffner-Cavaillon, and M. Goldman. 1997. Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway. J. Immunol. 158: 2919-2925. (Pubitemid 127470554)
    • (1997) Journal of Immunology , vol.158 , Issue.6 , pp. 2919-2925
    • Verhasselt, V.1    Buelens, C.2    Willems, F.3    De Groote, D.4    Haeffner-Cavaillon, N.5    Goldman, M.6
  • 21
    • 0035469894 scopus 로고    scopus 로고
    • Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation
    • Morelli, A. E., A. F. Zahorchak, A. T. Larregina, B. L. Colvin, A. J. Logar, T. Takayama, L. D. Falo, and A. W. Thomson. 2001. Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation. Blood 98: 1512-1523.
    • (2001) Blood , vol.98 , pp. 1512-1523
    • Morelli, A.E.1    Zahorchak, A.F.2    Larregina, A.T.3    Colvin, B.L.4    Logar, A.J.5    Takayama, T.6    Falo, L.D.7    Thomson, A.W.8
  • 22
    • 23344436170 scopus 로고    scopus 로고
    • Functional interactions of HPK1 with adaptor proteins
    • Boomer, J. S., and T. H. Tan. 2005. Functional interactions of HPK1 with adaptor proteins. J. Cell. Biochem. 95: 34-44.
    • (2005) J. Cell. Biochem. , vol.95 , pp. 34-44
    • Boomer, J.S.1    Tan, T.H.2
  • 23
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13: 251-276.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 24
    • 0031114121 scopus 로고    scopus 로고
    • Characterization of expression, cytokine regulation, and effector function of the high affinity IgG receptor Fc γ RI (CD64) expressed on human blood dendritic cells
    • Fanger, N. A., D. Voigtlaender, C. Liu, S. Swink, K. Wardwell, J. Fisher, R. F. Graziano, L. C. Pfefferkorn, and P. M. Guyre. 1997. Characterization of expression, cytokine regulation, and effector function of the high affinity IgG receptor Fc γ RI (CD64) expressed on human blood dendritic cells. J. Immunol. 158: 3090-3098.
    • (1997) J. Immunol. , vol.158 , pp. 3090-3098
    • Fanger, N.A.1    Voigtlaender, D.2    Liu, C.3    Swink, S.4    Wardwell, K.5    Fisher, J.6    Graziano, R.F.7    Pfefferkorn, L.C.8    Guyre, P.M.9
  • 25
    • 0029148878 scopus 로고
    • Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
    • Sallusto, F., M. Cella, C. Danieli, and A. Lanzavecchia. 1995. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J. Exp. Med. 182: 389-400.
    • (1995) J. Exp. Med. , vol.182 , pp. 389-400
    • Sallusto, F.1    Cella, M.2    Danieli, C.3    Lanzavecchia, A.4
  • 26
    • 3543053363 scopus 로고    scopus 로고
    • Immature dendritic cells phagocytose apoptotic cells via α vβ 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
    • Albert, M. L., S. F. A. Pearce, L. M. Francisco, B. Sauter, P. Roy, R. L. Silverstein, and N. Bhardwaj. 1998. Immature dendritic cells phagocytose apoptotic cells via α vβ 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes. J. Exp. Med. 188: 1359-1368.
    • (1998) J. Exp. Med. , vol.188 , pp. 1359-1368
    • Albert, M.L.1    Pearce, S.F.A.2    Francisco, L.M.3    Sauter, B.4    Roy, P.5    Silverstein, R.L.6    Bhardwaj, N.7
  • 27
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176: 1693-1702.
    • (1992) J. Exp. Med. , vol.176 , pp. 1693-1702
    • Inaba, K.1    Inaba, M.2    Romani, N.3    Aya, H.4    Deguchi, M.5    Ikehara, S.6    Muramatsu, S.7    Steinman, R.M.8
  • 31
    • 0036199656 scopus 로고    scopus 로고
    • Dendritic cell development and survival require distinct NF-κB subunits
    • DOI 10.1016/S1074-7613(02)00272-8
    • Ouaaz, F., J. Arron, Y. Zheng, Y. Choi, and A. A. Beg. 2002. Dendritic cell development and survival require distinct NF-κB subunits. Immunity 16: 257-270. (Pubitemid 34211965)
    • (2002) Immunity , vol.16 , Issue.2 , pp. 257-270
    • Ouaaz, F.1    Arron, J.2    Zheng, Y.3    Choi, Y.4    Beg, A.A.5
  • 32
    • 0030961008 scopus 로고    scopus 로고
    • Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor β (TGF-β)-activated kinase (TAK1), a kinase mediator of TGF β signal transduction
    • DOI 10.1074/jbc.272.36.22771
    • Wang, W., G. Zhou, M. C. Hu, Z. Yao, and T. H. Tan. 1997. Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun Nterminal kinase (JNK) pathway by transforming growth factor β (TGF-β) -activated kinase (TAK1), a kinase mediator of TGF-β β signal transduction. J. Biol. Chem. 272: 22771-22775. (Pubitemid 27386096)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.36 , pp. 22771-22775
    • Wang, W.1    Zhou, G.2    Hu, M.C.-T.3    Yao, Z.4    Tan, T.-H.5
  • 33
    • 0033518126 scopus 로고    scopus 로고
    • Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1)
    • Chen, Y. R., C. F. Meyer, B. Ahmed, Z. Yao, and T. H. Tan. 1999. Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1). Oncogene 18: 7370-7377.
    • (1999) Oncogene , vol.18 , pp. 7370-7377
    • Chen, Y.R.1    Meyer, C.F.2    Ahmed, B.3    Yao, Z.4    Tan, T.H.5
  • 34
    • 0036682941 scopus 로고    scopus 로고
    • Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes
    • DOI 10.1182/blood-2002-01-0089
    • Schulze-Luehrmann, J., B. Santner-Nanan, M. K. Jha, A. Schimpl, A. Avots, and E. Serfling. 2002. Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes. Blood 100: 954-960. (Pubitemid 34832623)
    • (2002) Blood , vol.100 , Issue.3 , pp. 954-960
    • Schulze-Luehrmann, J.1    Santner-Nanan, B.2    Jha, M.K.3    Schimpl, A.4    Avots, A.5    Serfling, E.6
  • 36
    • 23244465355 scopus 로고    scopus 로고
    • TLR4 and toll-IL-1 receptor domain-containing adapter-inducing IFN-β, but not MyD88, regulate Escherichia coli-induced dendritic cell maturation and apoptosis in vivo
    • De Trez, C., B. Pajak, M. Brait, N. Glaichenhaus, J. Urbain, M. Moser, G. Lauvau, and E. Muraille. 2005. TLR4 and Toll-IL-1 receptor domain-containing adapter-inducing IFN-β, but not MyD88, regulate Escherichia coli-induced dendritic cell maturation and apoptosis in vivo. J. Immunol. 175: 839-846. (Pubitemid 41094966)
    • (2005) Journal of Immunology , vol.175 , Issue.2 , pp. 839-846
    • De Trez, C.1    Pajak, B.2    Brait, M.3    Glaichenhaus, N.4    Urbain, J.5    Moser, M.6    Lauvau, G.7    Muraille, E.8
  • 37
    • 33644777565 scopus 로고    scopus 로고
    • CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells
    • DOI 10.1182/blood-2005-07-2913
    • Frasca, L., G. Fedele, S. Deaglio, C. Capuano, R. Palazzo, T. Vaisitti, F. Malavasi, and C. M. Ausiello. 2006. CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells. Blood 107: 2392-2399. (Pubitemid 43345559)
    • (2006) Blood , vol.107 , Issue.6 , pp. 2392-2399
    • Frasca, L.1    Fedele, G.2    Deaglio, S.3    Capuano, C.4    Palazzo, R.5    Vaisitti, T.6    Malavasi, F.7    Ausiello, C.M.8
  • 38
    • 37049019709 scopus 로고    scopus 로고
    • Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes
    • DOI 10.1182/blood-2007-01-071167
    • Brenner, D., A. Golks, M. Becker, W. Muller, C. R. Frey, R. Novak, D. Melamed, F. Kiefer, P. H. Krammer, and R. Arnold. 2007. Caspase cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes. Blood 110: 3968-3977. (Pubitemid 350248452)
    • (2007) Blood , vol.110 , Issue.12 , pp. 3968-3977
    • Brenner, D.1    Golks, A.2    Becker, M.3    Muller, W.4    Frey, C.R.5    Novak, R.6    Melamed, D.7    Kiefer, F.8    Krammer, P.H.9    Arnold, R.10
  • 39
    • 29244440885 scopus 로고    scopus 로고
    • Activation or suppression of NFκB by HPK1 determines sensitivity to activation-induced cell death
    • DOI 10.1038/sj.emboj.7600894
    • Brenner, D., A. Golks, F. Kiefer, P. H. Krammer, and R. Arnold. 2005. Activation or suppression of NFκB by HPK1 determines sensitivity to activation-induced cell death. EMBO J. 24: 4279-4290. (Pubitemid 41828903)
    • (2005) EMBO Journal , vol.24 , Issue.24 , pp. 4279-4290
    • Brenner, D.1    Golks, A.2    Kiefer, F.3    Krammer, P.H.4    Arnold, R.5
  • 40
  • 42
    • 33745712871 scopus 로고    scopus 로고
    • Dendritic cells in a mature age
    • Reis e Sousa, C. 2006. Dendritic cells in a mature age. Nat. Rev. Immunol. 6: 476-483.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 476-483
    • Reis E Sousa, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.