Medial temporal lobe activity can distinguish between old and new stimuli independently of overt behavioral choice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 34, 2009, Pages 14617-14621

  Brock Kirwan, C ^a   Shrager, Yael ^b   Squire, Larry R ^a,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

fMRI; Hippocampus; Parahippocampal gyrus; Recognition memory

Indexed keywords

ADULT; ARTICLE; BEHAVIOR; BRAIN DEPTH STIMULATION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; HUMAN EXPERIMENT; MALE; MEMORY; NORMAL HUMAN; PRIORITY JOURNAL; RECOGNITION; SUBICULUM; TASK PERFORMANCE; TEMPORAL LOBE;

ADULT; ANALYSIS OF VARIANCE; BRAIN MAPPING; CHOICE BEHAVIOR; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MENTAL RECALL; PATTERN RECOGNITION, VISUAL; PSYCHOMOTOR PERFORMANCE; REACTION TIME; TEMPORAL LOBE; VISUAL PERCEPTION; WORD ASSOCIATION TESTS; YOUNG ADULT;

EID: 70149118547     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0907624106     Document Type: Article

References (34)

1. Squire LR, Clark RE, Bayley PJ (2004) in Medial Temporal Lobe Function and Memory. The Cognitive Neurosciences, ed Gazzaniga M, 3rd Ed (MIT Press, Cambridge, MA).
2. Gonsalves BD, Kahn I, Curran T, Norman KA, Wagner AD (2005) Memory strength and repetition suppression: Multimodal imaging of medial temporal cortical contributions to recognition. Neuron 47:751-761. (Pubitemid 41208012)
3. Yonelinas AP, Otten LJ, Shaw KN, Rugg MD (2005) Separating the brain regions involved in recollection and familiarity in recognition memory. J Neurosci 25:3002-3008. (Pubitemid 40389258)
4. Daselaar SM, Fleck MS, Cabeza R (2006) Triple dissociation in the medial temporal lobes: Recollection, familiarity, and novelty. J Neurophysiol 96:1902-1911.
5. Montaldi D, Spencer TJ, Roberts N, Mayes AR (2006) The neural system that mediates familiarity memory. Hippocampus 16:504-520. (Pubitemid 44712075)
6. Tendolkar I, et al. (2007) Probing the neural correlates of associative memory formation: A parametrically analyzed event-related functional MRI study. Brain Res 1142:159-168. (Pubitemid 46420690)
7. Shrager Y, Kirwan CB, Squire LR (2008) Activity in both hippocampus and perirhinal cortex predicts the memory strength of subsequently remembered information. Neuron 59:547-553.
8. Kirwan CB, Wixted JT, Squire LR (2008) Activity in the medial temporal lobe predicts memory strength, whereas activity in the prefrontal cortex predicts recollection. J Neurosci 28:10541-10548.
9. Squire LR, Wixted JT, Clark RE (2007) Recognition memory and the medial temporal lobe: A new perspective. Nat Rev Neurosci 8:872-883. (Pubitemid 350006215)
10. Schacter DL, Alpert NM, Savage CR, Rauch SL, Albert MS (1996) Conscious recollection and the human hippocampal formation: Evidence from positron emission tomography. Proc Natl Acad Sci USA 93:321-325.
11. Stern CE, et al. (1996) The hippocampal formation participates in novel picture encoding: Evidence from functional magnetic resonance imaging. Proc Natl Acad Sci USA 93:8600-8665.
12. Daselaar SM, Fleck MS, Prince SE, Cabeza R (2006) The medial temporal lobe distinguishes old from new independently of consciousness. J Neurosci 26:5835-5839.
13. Chua EF, Schacter DL, Rand-Giovannetti E, Sperling RA (2006) Understanding metamemory: Neural correlates of the cognitive process and subjective level of con- fidence in recognition memory. NeuroImage 29:1150-1160. (Pubitemid 43184179)
14. Moritz S, Glascher J, Sommer T, Buchel C, Braus DF (2006) Neural correlates of memory confidence. NeuroImage 33:1188-1193.
15. Messinger A, Squire LR, Zola SM, Albright TD (2005) Neural correlates of knowledge: Stable representation of stimulus associations across variations in behavioral performance. Neuron 48:359-371. (Pubitemid 41476367)
16. Slotnick SD, Schacter DL (2004) A sensory signature that distinguishes true from false memories. Nat Neurosci 7:664-672.
17. Gabrieli JD, Brewer JB, Desmond JE, Glover GH (1997) Separate neural bases of two fundamental memory processes in the human medial temporal lobe. Science 276:264-266.
18. Rombouts SA, et al. (1999) Parametric fMRI analysis of visual encoding in the human medial temporal lobe. Hippocampus 9:637-643. (Pubitemid 30018854)
19. Rombouts SA, Barkhof F, Witter MP, Machielsen WC, Scheltens P (2001) Anterior medial temporal lobe activation during attempted retrieval of encoded visuospatial scenes: An event-related fMRI study. Neuroimage 14:67-76. (Pubitemid 32552744)
20. Fernandez G, Tendolkar I (2006) The rhinal cortex: 'Gatekeeper' of the declarative memory system. Trends Cogn Sci 10:358-362.
21. Brown MW, Xiang JZ (1998) Recognition memory: Neuronal substrates of the judgement of prior occurrence. Prog Neurobiol 55:149-189.
22. Henson RN, Cansino S, Herron JE, Robb WG, Rugg MD (2003) A familiarity signal in human anterior medial temporal cortex? Hippocampus 13:301-304. (Pubitemid 36503542)
23. Kumaran D, Maguire EA (2009) Novelty signals: A window into hippocampal information processing. Trends Cogn Sci 13:47-54.
24. Wilson MD (1988) The MRC Psycholinguistic Database: Machine readable dictionary, Version 2 Behavioral Research Methods, Instruments and Computers 20:6-11.
25. Stark CEL, Squire LR (2001) When zero is not zero: The problem of ambiguous baseline conditions in fMRI. Proc Natl Acad Sci USA 98:12760-12766.
26. Cox RW (1996) AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res 29:162-163.
27. Talairach J, Tournoux P (1988) in A Co-planar Stereotaxic Atlas of the Human Brain (Thieme Medical, New York).
28. Miller MI, Beg MF, Ceritoglu C, Stark C (2005) Increasing the power of functional maps of the medial temporal lobe by using large deformation diffeomorphic metric mapping. Proc Natl Acad Sci USA 102:9685-9690. (Pubitemid 40981741)
29. Kirwan CB, Jones CK, Miller MI, Stark CEL (2007) High-resolution fMRI investigation of the medial temporal lobe. Hum Brain Mapp 28:959-966. (Pubitemid 47549701)
30. Yassa MA, Stark CE (2009) A quantitative evaluation of cross-participant registration techniques for MRI studies of the medial temporal lobe. Neuroimage 44:319-327.
31. Insausti R, et al. (1998)MRvolumetric analysis of the human entorhinal, perirhinal, and temporopolar cortices. Am J Neuroradiol 19:659-671. (Pubitemid 30422709)
32. Insausti R, Insausti AM, Sobreviela M, Salinas A, Martinez-Penuela J (1998) Human medial temporal lobe in aging: Anatomical basis of memory preservation. Microsc Res Tech 43:8-15. (Pubitemid 28507007)
33. Forman SD, et al. (1995) Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): Use of a cluster-size threshold. Magn Reson Med 33:636-647.
34. Xiong JH, Gao JH, Lancaster JL, Fox PT (1995) Clustered pixels analysis for functional MRI activation studies of the human brain. Human Brain Mapp 3:287-301.