Synthesis and characterization of new liver targeting 5-fluorouracil-cholic acid conjugates

Archiv der Pharmazie

Volumn 342, Issue 9, 2009, Pages 513-520

  Qian, Shan ^a   Wu, Jian Bo ^a   Wu, Xiao Chun ^a   Li, Jie ^a   Wu, Yong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

5 Fluorouracil; Cholic acid; Liver; Prodrugs; Targeting

Indexed keywords

CHOLIC ACID DERIVATIVE; FLUOROURACIL DERIVATIVE;

ACIDIFICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DECOMPOSITION; DRUG DISTRIBUTION; DRUG STABILITY; DRUG SYNTHESIS; DRUG TISSUE LEVEL; FEASIBILITY STUDY; FEMALE; HEATING; HYDROLYSIS; IN VITRO STUDY; LIVER CARCINOMA; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; SEPARATION TECHNIQUE; SINGLE DRUG DOSE; TEMPERATURE;

ANIMALS; ANTINEOPLASTIC AGENTS; CHOLIC ACID; DRUG DELIVERY SYSTEMS; FEMALE; FLUOROURACIL; LIVER; MICE; MOLECULAR STRUCTURE; PRODRUGS; TISSUE DISTRIBUTION;

EID: 70149117266     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200900075     Document Type: Article

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