Primary ovarian dysfunction contributes to the hypogonadism in women with prader-willi syndrome

Hormone Research

Volumn 72, Issue 3, 2009, Pages 153-159

  Eldar Geva, Talia ^a   Hirsch, Harry J ^a   Rabinowitz, Ron ^a   Benarroch, Fortu ^b   Rubinstein, Orit ^a   Gross Tsur, Varda ^a  

^a SHAARE ZEDEK MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Anti M llerian hormone; Inhibin B; Ovarian function; Ovarian ultrasonography; Prader Willi syndrome

Indexed keywords

ANDROSTENEDIONE; ESTRADIOL; FOLLITROPIN; INHIBIN B; LUTEINIZING HORMONE; MEDROXYPROGESTERONE ACETATE; MUELLERIAN INHIBITING FACTOR; PRASTERONE SULFATE; PROLACTIN; TESTOSTERONE; THYROTROPIN;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AMENORRHEA; ANDROSTENEDIONE BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; ECHOGRAPHY; ESTRADIOL BLOOD LEVEL; FEMALE; FOLLITROPIN BLOOD LEVEL; HUMAN; HYPOGONADISM; LUTEINIZING HORMONE BLOOD LEVEL; MENSTRUAL CYCLE; ORGAN SIZE; OVARY; OVARY FOLLICLE; OVARY INSUFFICIENCY; PRADER WILLI SYNDROME; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PROTEIN BLOOD LEVEL; TESTOSTERONE BLOOD LEVEL; THYROTROPIN BLOOD LEVEL; WITHDRAWAL BLEEDING;

ADOLESCENT; ADULT; ANDROGENS; ANTI-MULLERIAN HORMONE; FEMALE; FOLLICLE STIMULATING HORMONE; HUMANS; HYPOGONADISM; HYPOTHALAMUS; INHIBINS; OVARIAN DISEASES; OVARY; PITUITARY GLAND; PRADER-WILLI SYNDROME; PROSPECTIVE STUDIES; UTERUS;

EID: 70149116006     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000232489     Document Type: Article

References (38)

1. Cassidy SB: Prader-Willi syndrome. J Med Genet 1997; 34: 917-923.
2. Wattendorf DJ, Muenke M: Prader-Willi syndrome. Am Fam Physician 2005; 72: 827-830.
3. Goldstone AP: Prader-Willi syndrome: advances in genetics, pathophysiology and treatment. Trends Endocrinol Metab 2004; 15: 12-20.
4. Benarroch F, Hirsch HJ, Genstil L, Landau Y, Gross-Tsur V: Prader-Willi syndrome: medical prevention and behavioral challenges. Child Adolesc Psychiatr Clin N Amer 2007; 16: 695-708.
5. Glaser B, Hirsch HJ: Genetics for Endocrinologists: The Molecular Genetic Basis of Endocrine Disorders. London, Remedica Publishing, 2000, pp 70-73.
6. Swaab DF: Prader-Willi syndrome and the hypothalamus. Acta Paediatr Suppl 1997; 423: 50-54.
7. Beccaria L, Benzi F, Bosio L, Corrias A, Gar-gantini L, Salvatoni A, Tonini G, Livieri C; Genetic Obesity Study Group of Italian Society of Pediatric Endocrinology and Diabetology (SIEDP): Hypogonadism and pubertal development in Prader-Willi syndrome. Eur J Pediatr 2003; 162: 327-333.
8. Eiholzer U, Schlumpf M, Gasser T, Girard J, Grüters A, Simoni M: Hypothalamic and gonadal components of hypogonadism in boys with Pra-der-Labhart-Willi syndrome. J Clin Endo-crinol Metab 2006; 91: 892-898.
9. Burman P, Ritzén EM, Lindgren AC: Endocrine dysfunction in Prader-Willi syndrome: a review with special reference to GH. En-docr Rev 2001; 22: 787-799.
10. Eiholzer U, Grieser J, Schlumpf M, mand D: Clinical effects of treatment for hypogonadism in male adolescents with Prader-Labhart-Willi syndrome. Horm Res 2007; 68: 178-184.
11. Muscatelli F, Abrous DN, Massacrier A, Boc-caccio I, Le Moal M, Cau P, Cremer H: Disruption of the mouse Necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome. Hum Mol Genet 2000; 12: 3101-3110.
12. Jeffcoate WJ, Laurance BM, Edwards CR, Besser GM: Endocrine function in the Pra-der-Willi syndrome. Clin Endocrinol (Oxf) 1980; 12: 81-89.
13. Akefeldt A, Törnhage CJ, Gillberg C: A woman with Prader-Willi syndrome gives birth to a healthy baby girl. Dev Med Child Neurol 1999; 41: 789-790.
14. Schulze A, Mogensen H, Hamborg-Petersen B, Graem N, Ostergaard JR, Brøndum-Nielsen K: Fertility in Prader-Willi syndrome: a case report with Angelman syndrome in the offspring. Acta Paediatr 2001; 90: 455-459.
15. Weenen C, Laven JS, von Bergh AR, Cran-field M, Groome NP, Visser JA, Kramer P, Fauser BC, Themmen AP: Anti-Müllerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment. Mol Hum Reprod 2004; 10: 77-83.
16. Fanchin R, Schonauer LM, Righini C, Gui-bourdenche J, Frydman R, Taieb J: Serum anti-Müllerian hormone is more strongly related to ovarian follicular status than serum inhibin B, estradiol, FSH and LH on day 3. Hum Reprod 2003; 18: 323-327.
17. Groome NP, Illingworth PJ, R, Rodger FE, Mather JP, McNeilly AS: Measurement of dimeric inhibin B throughout the human menstrual cycle. J Clin Endocri-nol Metab 1996; 81: 1401-1405.
18. Messinis IE: Ovarian feedback, mechanism of action and possible A, Schiaffini R, Ciampaliniclinical implications. Hum Reprod Update 2006; 12: 557-571.
19. Lee MM, Donahoe PK, Hasegawa T, Silverman B, Crist GB, Best S, Hasegawa Y, Noto RA, Schoenfeld D, MacLaughlin DT: Mul-lerian inhibiting substance in humans: normal levels from infancy to adulthood. J Clin Endocrinol Metab 1996; 81: 571-576.
20. Kwee J, Schats R, McDonnell J, Themmen D,A, de Jong F, Lambalk C: Evaluation of anti-Müllerian hormone as a test for the prediction of ovarian reserve. Fertil Steril 2008; 90: 737-743.
21. Eldar-Geva T, Ben-Chetrit A, Spitz IM, Rabi-nowitz R, Markowitz E, Mimoni T, Gal M, Zylber-Haran E, Margalioth EJ: Dynamic assays of inhibin B, anti-Mullerian hormone and estradiol following FSH stimulation and ovarian ultrasonography as predictors of IVF outcome. Hum Reprod 2005; 20: 3178-3183.
22. Sehested A, Juul AA, Andersson AM, Petersen JH, Jensen TK, Müller J, Skakkebaek NE: Serum inhibin A and inhibin B in healthy prepubertal, pubertal, and adolescent girls and adult women: relation to age, stage of puberty, menstrual cycle, follicle-stimulating hormone, luteinizing hormone, and estradi-ol levels. J Clin Endocrinol Metab 2000; 85: 1634-1640.
23. Crisosto N, Codner E, Maliqueo M, Echi-burú B, mann T: Anti-Müllerian hormone levels in peripubertal daughters of women with poly-cystic ovary syndrome. J Clin Endocrinol Metab 2007; 92: 2739-2743.
24. Codner E, Mook-Kanamori D, Bazaes RA, Unanue N, Sovino H, Ugarte F, Avila A, guez G, Cassorla F: Ovarian function during puberty in girls with type 1 diabetes melli-tus: response to leuprolide. J Clin Endocrinol Metab 2005; 90: 3939-3945.
25. Speroff L, Fritz MA: Clinical Gynecologic Endocrinology and Infertility, ed 7. Philadelphia, Lippincott Williams & Wilkins, 2005, pp 1304.
26. Roberts VJ, Barth S, el-Roeiy A, Yen SS: Expression of inhibin/activin subunits and fol-listatin messenger ribonucleic acids and proteins in ovarian follicles and the corpus luteum during the human menstrual cycle. J Clin Endocrinol Metab 1993; 77: 1402-1410.
27. Wachs DS, Coffler MS, Malcom PJ, Chang RJ: Serum anti-mullerian hormone concentrations are not altered by acute administration of follicle stimulating hormone in poly-cystic ovary syndrome and normal women. J Clin Endocrinol Metab 2007; 92: 1871-1874.
28. Hamilton CR Jr, Scully RE, Kliman B: Hypo-gonadotropinism in Prader-Willi syndrome. Induction of puberty and sperm altogenesis by clomiphene citrate. Am J Med 1972; 52: 322-329.
29. McGuffin WL Jr, Rogol AD: Response to LH- Spera S,RH and clomiphene citrate in two women with the Prader-Labhart-Willi syndrome. J Clin Endocrinol Metab 1975; 41: 325-331.
30. Linde R, McNeil L, Rabin D: Induction of menarche by clomiphene citrate in a fifteen-year-old girl with the Prader-Labhart-Willi syndrome. Fertil Steril 1982; 37: 118-120.
31. de Lind van Wijngaarden RF, Otten BJ, Fes-RoussontenV,DA, Joosten KF, de Jong FH, Sweep FC, Hokken-Koelega AC: High prevalence of central adrenal insufficiency in patients with Prader-Willi syndrome. J Clin Endocrinol Metab 2008; 93: 1649-1654.
32. Treasure JL, Wheeler M, King EA, Gordon PA, Russell GF: Weight gain and reproductive function: ultrasonographic and endocrine features in anorexia nervosa. Clin En-docrinol (Oxf) 1988; 29: 607-616.
33. Jonard S, Pigny P, Jacquesson L, Demerle- -Roux C, Robert Y, Dewailly D: The ovarian markers of the FSH insufficiency in functional hypothalamic amenorrhoea. Hum Reprod 2005; 20: 101-107.
34. van Elburg AA, Eijkemans MJ, Kas MJ, Themmen AP, de Jong FH, van Engeland H, Fauser BC: Predictors of recovery of ovarian function during weight gain in anorexia ner-vosa. Fertil Steril 2007; 87: 902-908.
35. Harwood K, Vuguin P, DiMartino-Nardi J: Current approaches to the diagnosis and treatment of polycystic ovarian syndrome in youth. Horm Res 2007; 68: 209-217.
36. Chen MJ, Yang WS, Chen CL, Wu MY, Yang YS, Ho HN: The relationship between anti-Mullerian hormone, androgen and insulin resistance on the number of antral follicles in women with polycystic ovary syndrome. Hum Reprod 2008; 23: 952-957.
37. Maggioni A: Effects of growth hormone therapy on glucose metabolism and insulin sensitivity indices in prepubertal children with Prader-Willi syndrome. Horm Res 2007; 68: 83-90.
38. Mapendano CK, Kishino T, Miyazaki K, Kondo S, Yoshiura K, Hishikawa Y, Koji T, Niikawa N, Ohta T: Expression of the Snurf-Snrpn IC transcript in the oocyte and its putative role in the imprinting establishment of the mouse 7C imprinting domain. J Hum Genet 2006; 51: 236-243.