Toward a multimodal cell analysis of brush biopsies for the early detection of oral cancer

Cancer Cytopathology

Volumn 117, Issue 3, 2009, Pages 228-235

  Remmerbach, Torsten W ^a,b   Meyer Ebrecht, Dietrich ^c   Aach, Til ^c   Würflinger, Thomas ^c   Bell, Andre A ^c   Schneider, Timna E ^c   Nietzke, Nadja ^d   Frerich, Bernhard ^b   Böcking, Alfred ^d  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b GRIFFITH UNIVERSITY   (Australia)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

AgNOR analysis; Argyrophilic nucleolar organizer regions; Brush biopsy; Cytology; DNA cytometry; Multinodal cell analysis; Oral carcinoma; Sensitivity; Specificity

Indexed keywords

CELL NUCLEUS ANTIGEN; DNA; NUCLEOLAR ORGANIZER REGION ASSOCIATED PROTEINS;

ADULT; AGED; ARTICLE; BIOPSY; CHEMISTRY; CHROMOSOME NOR; EARLY DIAGNOSIS; GENETICS; HUMAN; IMAGE CYTOMETRY; METABOLISM; METHODOLOGY; MIDDLE AGED; MOUTH MUCOSA; MOUTH TUMOR; PATHOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SILVER STAINING; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, NUCLEAR; BIOPSY; CARCINOMA, SQUAMOUS CELL; DNA, NEOPLASM; EARLY DIAGNOSIS; HUMANS; IMAGE CYTOMETRY; MIDDLE AGED; MOUTH MUCOSA; MOUTH NEOPLASMS; NUCLEOLUS ORGANIZER REGION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SILVER STAINING;

EID: 70149111578     PISSN: None     EISSN: 19346638     Source Type: Journal    
DOI: 10.1002/cncy.20028     Document Type: Article

References (37)

1. Franceschi S, Bidoli E, Herrero R, Munoz N. Comparison of cancers of the oral cavity and pharynx worldwide: etiological clues. Oral Oncol. 2000; 36: 106-115.
2. Weir JC, Davenport WD, Skinner RL. A diagnostic and epidemiologic survey of 15,783 oral lesions. J Am Dent Assoc. 1987; 115: 439-442.
3. Schon D, Bertz J, Hoffmeister H. Bevolkerungsbezogene Krebsregister in der Bundesrepublik Deutschland, [2] 374. Berlin, Germany: Robert Koch Institut Schriften; 1995.
4. Schon D, Bertz J, Gorsch B, Haberland J, Kurth BM. Federal Cancer Reporting Unit. Surveillance program for cancer registration in Germany [article in German]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2004; 47: 429-436.
5. Howald HP, Kainz M. Zentralregister des DOSAK fur Tumoren im Kiefer-Gesichtsbereich, 7. Projektbericht. Gieen, Germany: Zentrales Tumorregister des DOSAK; 1996.
6. Howald HP, Frenz M, Pitz H. Results from DOSAK observational studies. In: Pape HD, Ganzer U, Schmitt G, eds. Carcinoma of the Oral Cavity and Oropharynx. Berlin, Germany: Springer-Verlag; 2005: 173-182.
7. Platz H, Fries R, Hudec M. Prognosis of Oral Cavity Carcinomas. Munich, Germany: Carl Hanser; 1986.
8. Stell PM, Wood GD, Scott MH. Early oral cancer: treatment by biopsy excision. Br J Oral Surg. 1982; 20: 234-238.
9. Pentenero M, Carrozzo M, Pagano M, et al. Oral mucosal dysplastic lesions and early squamous cell carcinomas: underdiagnosis from incisional biopsy. Oral Dis. 2003; 9: 68-72.
10. Carpi A, Ferrari E, Toni MG, Sagripanti A, Nicolini A, Di Coscio G. Needle aspiration techniques in preoperative selection of patients with thyroid nodules: a long-term study. J Clin Oncol. 1996; 14: 1704-1712.
11. Remmerbach T, Weidenbach H, Pomjanski N, et al. Cytologica and DNA-cytometric early diagnosis of oral cancer. Anal Cell Pathol. 2001; 22: 211-221.
12. Wurflinger T, Stockhausen J, Meyer-Ebrecht D, Bocking A. Robust automatic coregistration, segmentation, and classification of cell nuclei in multimodal cytopathological microscopic images. Comput Med Imaging Graph. 2004; 28: 87-98.
13. Bocking A, Stockhausen J, Meyer-Ebrecht D. Towards a single cell cancer diagnosis. Multimodal and monocellular measurements of markers and morphology (5M). Cell Oncol. 2004; 26: 73-79.
14. Duesberg P, Li R. Multistep carcinogenesis: a chain reaction of aneuploidizations. Cell Cycle. 2003; 2: 202-210.
15. Duesberg PH. Are cancers dependent on oncogenes or on aneuploidy? Cancer Genet Cytogenet. 2003; 143: 89-91.
16. Bocking A, Adler CP, Common HH, Hilgarth M, Granzen B, Auffermann W. Algorithm for a DNA-cytophotometric diagnosis and grading of malignancy. Anal Quant Cytol. 1984; 6: 1-8.
17. Bocking A, Striepecke E, Auer H, Fuzesi L. Static DNAcytometry. Biological background, technique and diagnostic interpretation. In: Wied GL, Keebler CM, Rosenthal D, Schenck U, Somrak TM, Vooijs G, eds. Compendium on Quality Assurance, Proficiency Testing, and Workload Limitations. Chicago, Ill: Tutorials of Cytology; 1994: 107-128.
18. Bocking A. DNA measurements. When and why? In: Wied GL, Keebler C, Rosenthal D, Schenck U, Somrack TM, Vooijs G, eds. Compendium on Quality Assurance, Proficiency Testing, and Workload Limitations. Chicago, Ill: Tutorials of Cytology; 1995: 170-188.
19. Haroske G, Meyer W, Oberholzer M, Bocking A, Kunze KD. Competence on demand in DNA image cytometry. Pathol Res Pract. 2000; 196: 285-291.
20. Haroske G, Baak JP, Danielsen H, et al. Fourth updated ESACP consensus report on diagnostic DNA image cytometry. Anal Cell Pathol. 2001; 23: 89-95.
21. Remmerbach TW, Weidenbach H, Muller, et al. Diagnostic value of nucleolar organizer regions (AgNORs) in brush biopsies of suspicious lesions of the oral cavity. Anal Cell Pathol. 2003; 25: 139-146.
22. Ruschoff J. Nucleolus organizer regions in pathomorphologic tumor diagnosis. Veroff Pathol. 1992; 139: 1-144.
23. Bell AA, Kaftan JM, Aach T, Meyer-Ebrecht D, Bocking A. High dynamic range images as a basis for detection of argyrophilic nucleolar organizer regions under varying stain intensities. In: Institute of Electrical and Electronics Engineers (IEEE), ed. Proceedings of the IEEE International Conference on Image Processing, ICIP 2006, Atlanta, Georgia, October 8-11, 2006. Washington, DC: IEEE; 2007: 2541-2544.
24. Aubele M, Biesterfeld S, Derenzini M, et al. Guidelines of AgNOR quantitation. Committee on AgNOR Quantitation within the European Society of Pathology. Zentralbl Pathol. 1994; 140: 107-108.
25. World Health Organization Collaborating Centre for Oral Precancerous Lesions. Definition of leukoplakia and related lesions: an aid to studies on oral precancerous lesions. Oral Surg Oral Med Oral Pathol. 1978; 4: 518-539.
26. van der Waal I, Schepman KP, van der Meij EH. A modified classification and staging system for oral leukoplakia. Oral Oncol. 2000; 36: 264-266.
27. Bocking A, Freudenberg N. Standardisierte Befunderstellung in der extragenitalen Zytologie. Pathologe. 1998; 19: 235-236.
28. Feulgen R, Rossenbeck H. Mikroskopisch-chemischer Nachweis einer Nucleinsaure vom Typus der Thymonnu-cleinsaure und die darauf beruhende elektive Farbung von Zellkernen in mikroskopischen Praparaten. Hoppe Seylers Z Physiol Chem. 1924; 135: 203-248.
29. Chatelain R, Willms A, Biesterfeld S, Auffermann W, Bocking A. Automated Feulgen staining with a temperature-controlled staining machine. Anal Quant Cytol Histol. 1989; 11: 211-217.
30. Schulte EK, Joos U, Kasper M, Eckert HM. Cytological detection of epithelial dysplasia in the oral mucosa using Feulgen-DNA-image cytometry. Diagn Cytopathol. 1991; 7: 436-441.
31. Bocking A, Giroud F, Reith A. Consensus report of the ESACP task force on standardization of diagnostic DNA image cytometry. European Society for Analytical Cellular Pathology. Anal Cell Pathol. 1995; 8: 67-74.
32. Haroske G, Giroud F, Reith A, Bocking A. 1997 ESACP consensus report on diagnostic DNA image cytometry. Part I: basic considerations and recommendations for preparation, measurement and interpretation. European Society for Analytical Cellular Pathology. Anal Cell Pathol. 1998; 17: 189-200.
33. Giroud F, Haroske G, Reith A, Bocking A. 1997 ESACP consensus report on diagnostic DNA image cytometry. Part II: specific recommendations for quality assurance. European Society for Analytical Cellular Pathology. Anal Cell Pathol. 1998; 17: 201-208.
34. Bell A, Wurflinger T, Ropers S-O, Bocking A, Aach T, Meyer-Ebrecht D. Towards fully automatic acquisition of multimodal cytopathological microscopy images with autofocus and scene matching. Methods Inf Med. 2007; 46: 314-323.
35. Nairn ER, Crocker J, McGovern J. Limited value of AgNOR enumeration in assessment of thyroid neoplasms. J Clin Pathol. 1988; 41:1136.
36. Crocker J, Boldy DA, Egan MJ. How should we count AgNORs? Proposals for a standardized approach. J Pathol. 1989; 158: 185-188.
37. Ploton D, Menager M, Jeannesson P, Himber G, Pigeon F, Adnet JJ. Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level. Histochem J. 1986; 18: 5-14.