Hepatic morphopathologic findings of lead poisoning in a drug addict: A case report

Journal of Gastrointestinal and Liver Diseases

Volumn 18, Issue 2, 2009, Pages 225-227

  Verheij, Joanne ^a   Voortman, Jens ^a   Van Nieuwkerk, Carin M J ^a   Jarbandhan, S Vijay A ^a   Mulder, Chris J J ^a   Bloemena, Elisabeth ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Hepatotoxicity; Iran; Liver biopsy; Opium

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DIMERCAPROL; EDETATE CALCIUM DISODIUM; GAMMA GLUTAMYLTRANSFERASE; OPIATE; PROTOPORPHYRIN ZINC; SUCCIMER; CHELATING AGENT; LEAD; PROTOPORPHYRIN;

ABDOMINAL PAIN; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CASE REPORT; CHOLANGITIS; CHOLESTASIS; CHRONIC PAIN; CLINICAL FEATURE; DRUG DEPENDENCE; EMERGENCY WARD; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HEMOSIDEROSIS; HISTOPATHOLOGY; HUMAN; IMMIGRANT; INTESTINE SOUND; LEAD POISONING; LIVER BIOPSY; LIVER DISEASE; LIVER FIBROSIS; LIVER TOXICITY; LYMPHOCYTIC INFILTRATION; MALE; NORMOCHROMIC NORMOCYTIC ANEMIA; STEATOSIS; SWEATING; ANEMIA; BLOOD; DRUG CONTAMINATION; DRUG EFFECT; FATTY LIVER; LIVER; OPIATE ADDICTION; PATHOLOGY; TOXIC HEPATITIS; TREATMENT OUTCOME;

ABDOMINAL PAIN; ADULT; ANEMIA; CHELATING AGENTS; CHOLANGITIS; DRUG CONTAMINATION; FATTY LIVER; HEMOSIDEROSIS; HEPATITIS, TOXIC; HUMANS; LEAD; LEAD POISONING; LIVER; MALE; OPIOID-RELATED DISORDERS; OPIUM; PROTOPORPHYRINS; TREATMENT OUTCOME;

EID: 70149111333     PISSN: 18418724     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Patrick L. Lead toxicity, a review of the literature. Part 1: Exposure, evaluation, and treatment. Altern Med Rev 2006; 11: 2-22.
2. Cairney S, Maruff P, Burns CB, Currie J, Currie BJ. Neurological and cognitive impairment associated with leaded gasoline encephalopathy. Drug Alcohol Depend 2004; 73: 183-188. (Pubitemid 38068355)
3. Rogan WJ, Dietrich KN, Ware JH, et al; Treatment of Lead-Exposed Children Trial Group. The effect of chelation therapy with succimer on neuropsychological development in children exposed to lead. N Engl J Med 2001; 344: 1421-1426.
4. Ochiai K, Jin K, Goryo M, Tsuzuki T, Itakura C. Pathomorphologic fi ndings of lead poisoning in white-fronted geese (Anser albifrons). Vet Pathol 1993; 30: 522-528.
5. Batuman V, Maesaka JK, Haddad B, Tepper E, Landy E, Wedeen RP. The role of lead in gout nephropathy. N Engl J Med 1981; 304: 520-523.
6. Beattie AD, Mullin PJ, Baxter RH, Moore MR. Acute lead poisoning: an unusual cause of hepatitis. Scott Med J 1979; 24: 318-321. (Pubitemid 10196989)
7. Masoodi M, Zali MR, Ehsani-Ardakani MJ, et al. Abdominal pain due to lead-contaminated opium: a new source of inorganic lead poisoning in Iran. Arch Iran Med 2006; 9: 72-75. (Pubitemid 43125297)
8. Papaioannou N, Vlemmas I, Balaskas N, Tsangaris T. Histopathological lesions in lead intoxicated dogs. Vet Hum Toxicol 1998; 40: 203-207. (Pubitemid 28340839)
9. Gürer H, Ozgünes H, Neal R, Spitz DR, Erçal N. Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats. Toxicology 1998; 128: 181-189. (Pubitemid 28380173)
10. Zimmerman HJ. Hepatotoxicity: the adverse effects of drugs and other chemicals on the liver. 2nd ed. Philadelphia: Lippincott- Willimas & Wilkins, 1999.