Effect of adenosine 5′-triphosphate infusions on the nutritional status and survival of preterminal cancer patients

Anti-Cancer Drugs

Volumn 20, Issue 7, 2009, Pages 625-633

  Beijer, Sandra ^a   Hupperets, Pierre S ^b   Van Den Borne, Ben E ^c   Eussen, Simone R ^a   Van Henten, Arjen M ^d   Van Den Beuken Van Everdingen, Marieke ^b   De Graeff, Alexander ^e   Ambergen, Ton A ^a   Van Den Brandt, Piet A ^a   Dagnelie, Pieter C ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c CATHARINA HOSPITAL   (Netherlands)

^d MÁXIMA MEDICAL CENTER   (Netherlands)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Adenosine 50 triphosphate; Nutritional status; Preterminal cancer; Survival

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANALGESIC AGENT; ANTIBIOTIC AGENT; ANTIDIABETIC AGENT; ANTIDIARRHEAL AGENT; ANTIEMETIC AGENT; ANTIHYPERTENSIVE AGENT; CORTICOSTEROID; DIURETIC AGENT; GEFITINIB; LAXATIVE;

AGED; ANALYSIS OF COVARIANCE; ARTICLE; CANCER MORTALITY; CANCER PATIENT; CANCER SURVIVAL; DRUG INFUSION; DYSPNEA; FEMALE; HEART MUSCLE ISCHEMIA; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MIXED TUMOR; NUTRITIONAL STATUS; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; SKINFOLD THICKNESS; THORAX PAIN; ANALYSIS OF VARIANCE; CACHEXIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FOLLOW UP; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; NEOPLASM; RANDOMIZED CONTROLLED TRIAL; SURVIVAL RATE;

ADENOSINE TRIPHOSPHATE; AGED; ANALYSIS OF VARIANCE; CACHEXIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; NEOPLASMS; NUTRITIONAL STATUS; PROPORTIONAL HAZARDS MODELS; SKINFOLD THICKNESS; SURVIVAL RATE;

EID: 70149105651     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32832d4f22     Document Type: Article

References (34)

1. Strasser F, Bruera ED. Update on anorexia and cachexia. Hematol Oncol Clin North Am 2002; 16:589-617.
2. Dewys WD, Begg C, Lavin PT, Band PR, Bennett JM, Bertino JR, et al. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern Cooperative Oncology Group. Am J Med 1980; 69:491-497.
3. Maltoni M, Caraceni A, Brunelli C, Broeckaert B, Christakis N, Eychmueller S, et al. Prognostic factors in advanced cancer patients: evidence-based clinical recommendations-a study by the Steering Committee of the European Association for Palliative Care. J Clin Oncol 2005; 23:6240-6248.
4. Warren S. The immediate cause of death. Am J Med Sci 1932; 184:610-615.
5. Tisdale MJ. Biology of cachexia. J Natl Cancer Inst 1997; 89:1763-1773.
6. Argiles JM, Busquets S, Moore-Carrasco R, Figueras M, Almendro V, Lopez-Soriano FJ. Targets in clinical oncology: the metabolic environment of the patient. Front Biosci 2007; 12:3024-3051.
7. Baracos VE. Cancer-associated cachexia and underlying biological mechanisms. Annu Rev Nutr 2006; 26:435-461.
8. Tisdale MJ. Cancer cachexia: metabolic alterations and clinical manifestations. Nutrition 1997; 13:1-7.
9. Yavuzsen T, Davis MP,Walsh D, LeGrand S, Lagman R. Systematic review of the treatment of cancer-associated anorexia and weight loss. J Clin Oncol 2005; 23:8500-8511.
10. Agteresch HJ, Dagnelie PC, van Der Gaast A, Stijnen T, Wilson JH. Randomized clinical trial of adenosine 50-triphosphate in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2000; 92:321-328.
11. Agteresch HJ, Rietveld T, Kerkhofs LG, van den Berg JW, Wilson JH, Dagnelie PC. Beneficial effects of adenosine triphosphate on nutritional status in advanced lung cancer patients: a randomized clinical trial. J Clin Oncol 2002; 20:371-378.
12. Agteresch HJ, Burgers SA, van der Gaast A, Wilson JH, Dagnelie PC. Randomized clinical trial of adenosine 5'-triphosphate on tumor growth and survival in advanced lung cancer patients. Anticancer Drugs 2003; 14:639-644.
13. Swennen EL, Bast A, Dagnelie PC. Immunoregulatory effects of adenosine 50-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol 2005; 35:852-858.
14. Swennen EL, Bast A, Dagnelie PC. Purinergic receptors involved in the immunomodulatory effects of ATP in human blood. Biochem Biophys Res Commun 2006; 348:1194-1199.
15. Beijer S, Gielisse EA, Hupperets PS, van den Borne BE, van den Beuken-van Everdingen M, Nijziel MR, et al. Intravenous ATP infusions can be safely administered in the home setting: a study in pre-terminal cancer patients. Invest New Drugs 2007; 25:571-579.
16. Stratton R, Green CJ, Elia M. Disease-related malnutrition: an evidence-based approach to treatment. Wallingford, CT: CABI Publishing; 2003.
17. Ravasco P, Monteiro-Grillo I, Vidal PM, Camilo ME. Nutritional deterioration in cancer: the role of disease and diet. Clin Oncol (R Coll Radiol) 2003; 15:443-450.
18. Fordy C, Glover C, Henderson DC, Summerbell C, Wharton R, Allen-Mersh TG. Contribution of diet, tumour volume and patient-related factors to weight loss in patients with colorectal liver metastases. Br J Surg 1999; 86:639-644.
19. Ravasco P, Monteiro-Grillo I, Camilo M. How relevant are cytokines in colorectal cancer wasting? Cancer J 2007; 13:392-398.
20. Correale P, Tagliaferri P, Guarrasi R, Caraglia M, Giuliano M, Marinetti MR, et al. Extracellular adenosine 50 triphosphate involvement in the death of LAK-engaged human tumor cells via P2X-receptor activation. Immunol Lett 1997; 55:69-78.
21. Schafer R, Hartig R, Sedehizade F, Welte T, Reiser G. Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor kappaB1 and mitogen-activated protein kinase pathways. FEBS J 2006; 273:3756-3767.
22. Conigrave AD, van der Weyden L, Holt L, Jiang L, Wilson P, Christopherson RI, et al. Extracellular ATP-dependent suppression of proliferation and induction of differentiation of human HL-60 leukemia cells by distinct mechanisms. Biochem Pharmacol 2000; 60:1585-1591.
23. Wang MX, Ren LM. Growth inhibitory effect and apoptosis induced by extracellular ATP and adenosine on human gastric carcinoma cells: involvement of intracellular uptake of adenosine. Acta Pharmacol Sin 2006; 27:1085-1092.
24. Shabbir M, Thompson C, Jarmulowiczc M, Mikhailidis D, Burnstock G. Effect of extracellular ATP on the growth of hormone-refractory prostate cancer in vivo. BJU Int 2008; 102:108-112.
25. Rapaport E. Experimental cancer therapy in mice by adenine nucleotides. Eur J Cancer Clin Oncol 1988; 24:1491-1497.
26. Shabbir M, Ryten M, Thompson C, Mikhailidis D, Burnstock G. Purinergic receptor-mediated effects of ATP in high-grade bladder cancer. BJU Int 2008; 101:106-112.
27. Agteresch HJ, Dagnelie PC, Rietveld T, van den Berg JW, Danser AH, Wilson JH. Pharmacokinetics of intravenous ATP in cancer patients. Eur J Clin Pharmacol 2000; 56:49-55.
28. Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev 1998; 50:413-492.
29. Grulke N, Bailer H. [Fighting spirit-a key to survival in cancer patients?]. MMW Fortschr Med 2007; 149:35-36.
30. Petticrew M, Bell R, Hunter D. Influence of psychological coping on survival and recurrence in people with cancer: systematic review. BMJ 2002; 325:1066-1075.
31. Stephen JE, Rahn M, Verhoef M, Leis A. What is the state of the evidence on the mind-cancer survival question, and where do we go from here? A point of view. Support Care Cancer 2007; 15:923-930.
32. Edwards AG, Hailey S, Maxwell M. Psychological interventions for women with metastatic breast cancer. Cochrane Database Syst Rev 2004; 2:CD004253.
33. Andersen BL, Yang HC, Farrar WB, Golden-Kreutz DM, Emery CF, Thornton LM, et al. Psychologic intervention improves survival for breast cancer patients. Cancer 2008; 113:3450-3458.
34. Haskell CM, Wong M, Williams A, Lee LY. Phase I trial of extracellular adenosine 50-triphosphate in patients with advanced cancer. Med Pediatr Oncol 1996; 27:165-173. (Pubitemid 26282097)