The immune response and fertility of koalas (Phascolarctos cinereus) immunised with porcine zonae pellucidae or recombinant brushtail possum ZP3 protein

Journal of Reproductive Immunology

Volumn 82, Issue 1, 2009, Pages 40-47

  Kitchener, Anne L ^a   Kay, David J ^a   Walters, Bryan ^b   Menkhorst, Peter ^c   McCartney, Carmen A ^a   Buist, Janine A ^a   Mate, Karen E ^a   Rodger, John C ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b Ecoplan Australia   (Australia)

^c Department of Sustainability and Environment ^*  (Australia)

Author keywords

Immunocontraception; Koala; Marsupial; Porcine zona pellucida; Recombinant ZP3

Indexed keywords

BUFFER; CONTRACEPTIVE VACCINE; EPITOPE; FREUND ADJUVANT; RECOMBINANT PROTEIN; RECOMBINANT ZONA PELLUCIDA PROTEIN 3; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CONTRACEPTION; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; FEMALE FERTILITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOCONTRACEPTION; KANGAROO; KOALA; MARSUPIAL; NONHUMAN; OVARY FOLLICLE FLUID; PRIORITY JOURNAL; RELIABILITY; SEQUENCE ANALYSIS; UTERUS FLUID; VAGINA SECRETION; ZONA PELLUCIDA;

ANIMALS; ANTIBODIES; ANTIBODY FORMATION; CONTRACEPTION, IMMUNOLOGIC; EGG PROTEINS; EPITOPE MAPPING; EPITOPES; FEMALE; FERTILITY; FREUND'S ADJUVANT; IMMUNIZATION, SECONDARY; INFERTILITY, FEMALE; OVARY; PHASCOLARCTIDAE; PREGNANCY; RECOMBINANT PROTEINS; SWINE; TISSUE EXTRACTS; TRICHOSURUS; ZONA PELLUCIDA;

EID: 70149099113     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2009.07.001     Document Type: Article

References (29)

1. Asquith K.L., Kitchener K.L., and Kay D.J. Immunisation of the male tammar wallaby (Macropus eugenii) with spermatozoa elicits epididymal antigen-specific antibody secretion and compromised fertilisation rate. J. Reprod. Immunol. 69 (2006) 127-147
2. Barber M.R., and Fayrer-Hosken R.A. Possible mechanisms of mammalian immunocontraception. J. Reprod. Immunol. 46 (2000) 103-124
3. Duckworth J.A., Buddle B.M., and Scobie S. Fertility of brushtail possums (Trichosurus vulpecula) immunised against sperm. J. Reprod. Immunol. 37 (1998) 125-138
4. Duckworth J.A., Harris M.H., Mate K.E., McCartney C.A., Buist J.M., Scobie S., Jones D., and Jones S. Development of brushtail possum immunocontraception: targeting sperm and egg antigens. Roy. Soc. N. Z. Misc. Ser. 56 (1999) 72-76
5. Duckworth J.A., Mate K.E., Scobie S., Jones D., Buist J.M., Molinia F.C., Glazier A., Cui X., Cowan P., Walmsley A., Kirk D., Lubitz W., and Haller C. Evaluating zona pellucida antigens and delivery systems for possum fertility control in New Zealand: progress and future directions. Biological Management of Possums: National Science Strategy Committee for Possum: Bovine Tb Control (2001), NZ Ministry of Agriculture, Forestry, Wellington
6. Duckworth J.A., Wilson K., Cui X., Molinia F.C., and Cowan P.E. Immunogenicitry and contraceptive potential of three infertility-relevant zona pellucida 2 epitopes in the marsupial brushtail possum (Trichosurus vulpecula). Reproduction 133 (2007) 177-186
7. Eidne K.A., Henery C.C., and Aitken R.J. Selection of peptides targeting the human sperm surface using random peptide phage display identify ligands homologous to ZP3. Biol. Reprod. 63 (2000) 1396-1402
8. Geysen H.M., Rodda S.J., Mason T.J., Tribbick G., and Schoofs P.G. Strategies for epitope analysis using peptide synthesis. J. Immunol. Methods 102 (1987) 259-274
9. Gupta S.K., Yurewicz E.C., Afzalpurkar A., Rao K.V., Gage D.A., Wu H., and Sacco A.G. Localization of epitopes for monoclonal antibodies at the N-terminus of the porcine zona pellucida glycoprotein pZPC. Mol. Reprod. Dev. 42 (1995) 220-225
10. Jackson M., White N., Giffard P., and Timms P. Epizootiology of Chlamydia infections in two free-range koala populations. Vet. Microbiol. 65 (1999) 255-264
11. Kay D.J., and Kitchener A.L. Immune response of the tammar wallaby (Macropus eugenii) to sperm antigens. Reprod. Fertil. Dev. 15 (2004) 429-437
12. Kirkpatrick J.F., Turner Jr. J.W., Liu I.K.M., and Fayrer-Hosken R. Applications of pig zona pellucida immunocontraception to wildlife fertility control. J. Reprod. Fertil. 50 (1996) 183-189
13. Kitchener A.L., Edds L.M., Molinia F.C., and Kay D.J. Porcine zonae pellucidae immunisation of tammar wallabies (Macropus eugenii): fertility and immune responses. Reprod. Fertil. Dev. 14 (2002) 215-223
14. Kitchener A.L., Harman A., Kay D.J., McCartney C.A., Mate K.E., and Rodger J.C. Immunocontraception of eastern grey kangaroos (Macropus giganteus) with porcine zonae pellucidae (ZP) and recombinant brushtail possum (Trichosurus vulpecula) ZP3 protein. J. Reprod. Immunol. 79 (2009) 156-162
15. Lee A.K., Martin R.W., and Handasyde K.A. Experimental translocation of koalas to new habitat. In: Lee A.K., Handasyde K.A., and Sanderson G.D. (Eds). Biology of the Koala (1990), Surrey Beatty & Sons, Chipping Norton, Australia 299-312
16. Lou Y.-H., Ang J., Thai H., McElveen M.F., and Tung K.S. A zona pellucida 3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology. J. Immunol. 155 (1995) 2715-2720
17. McCartney C.A., and Mate K.E. Cloning and characterisation of zona pellucida 3 cDNA from a marsupial, the brushtail possum, Trichosurus vulpecula. Zygote 7 (1999) 1-9
18. McCartney C.A., Harris M.S., Rodger J.C., and Mate K.E. Towards a ZP-based contraceptive for marsupials: comparative analysis and developmental expression of marsupial ZP genes. Mol. Reprod. Dev. 74 (2007) 1581-1589
19. McColl K.A., Martin R.W., Gleeson L.J., Handasyde K.A., and Lee A.K. Chlamydia infection and infertility in the female koala (Phascolarctos cinereus). Vet. Rec. 115 (1984) 655
20. Martin R.W. Overbrowsing and decline of a population of the koala, Phascolarctos cinereus, in Victoria. I. Food preference and food tree defoliation. Wildl. Res. 12 (1985) 355-365
21. Martin R.W., and Handasyde K.A. Population dynamics of the koala (Phascolarctos cinereus) in southeastern Australia. In: Lee A.K., Handasyde K.A., and Sanson G.D. (Eds). Biology of the Koala (1990), Surrey Beatty & Sons, Sydney, Australia 97-108
22. Martin R.W., and Handasyde K.A. The Koala: Natural History, Conservation and Management (1999), University of New South Wales Press, Sydney, Australia
23. Mate K.E., and Hinds L.A. Contraceptive vaccine development. In: Holt W.V., Pickard A.R., Rodger J.C., and Wildt D.E. (Eds). Reproductive Science and Integrated Conservation (2003), Cambridge University Press, Cambridge, UK 291-304
24. Mate K.E., Buist J.M., and Duckworth J.A. Expression in Escherichia coli and immunological characterization of three zona pellucida proteins (ZP1, ZP2 and ZP3) from a marsupial, the brushtail possum (Trichosurus vulpecula). Mol. Reprod. Dev. 64 (2003) 136-143
25. Menkhorst P. Victoria's Koala Management Strategy (2004), Department of Sustainability and Environment, Melbourne, Australia
26. Menkhorst, P., 2009. Hunted, marooned, re-introduced, contracepted: a history of Koala management in Victoria. In: Lunney, D., Munn, A., Meikle, W. (Eds.), To Close for Comfort. Contentious Issues in Human-Wildlife Encounters, Royal Zoological Society of New South Wales, Mosman, Australia, pp. 73-92.
27. Millar S.E., Chamow S.M., Baur A.W., Oliver C., Robey F., and Dean J. Vaccination with a synthetic zona pellucida peptide produces long-term contraception in female mice. Science 246 (1989) 935-938
28. Miller L.A., Johns B.E., and Killian G.J. Long-term effects of PZP immunization on reproduction in white-tailed deer. Vaccine 18 (2000) 568-574
29. Swanson W.J., Yang Z., Wolfner M.F., and Aquadro C.F. Positive Darwinian selection drives the evolution of several female reproductive proteins in mammals. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 2509-2514