Influence of dendritic cells on viral pathogenicity

PLoS Pathogens

Volumn 5, Issue 7, 2009, Pages

  Freer, Giulia ^a   Matteucci, Donatella ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DENDRITIC CELL VACCINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; CELL SURFACE; CYTOKINE RELEASE; DENDRITIC CELL; FELINE IMMUNODEFICIENCY VIRUS; HELPER CELL; HOST CELL; HUMAN; IMMUNE RESPONSE; NONHUMAN; PATHOGENESIS; PROGENY; REVIEW; T LYMPHOCYTE; VACCINATION; VIRUS ATTACHMENT; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; HOST PATHOGEN INTERACTION; IMMUNOLOGY; PATHOGENICITY; VIROLOGY; VIRUS;

ANIMALS; DENDRITIC CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; VIRUS DISEASES; VIRUSES;

EID: 70049116988     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000384     Document Type: Review

References (87)

1. Steinman RM (2007) Dendritic cells: understanding immunogenicity. Eur J Immunol 37: 53-60.
2. Macagno A, Napolitani G, Lanzavecchia A, Sallusto F (2007) Duration, combination and timing: the signal integration model of dendritic cell activation. Trends Immunol 28: 227-233. (Pubitemid 46654873)
3. de Jong EC, Smits HH, Kapsenberg ML (2005) Dendritic cell-mediated T cell polarization. Springer Semin Immunopathol 26: 289-307.
4. Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, et al. (2006) Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
5. Park H, Li Z, Yang XO, Chang SH, Nurieva R, et al. (2005) A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 6: 1133-1141. (Pubitemid 41541791)
6. Allenspach EJ, Lemos MP, Porrett PM, Turka LA, Laufer TM (2008) Migratory and lymphoid-resident dendritic cells cooperate to efficiently prime naive CD4 T cells. Immunity 29: 795-806.
7. Alexopoulou L, Holt AC, Medzhitov R, Flavell RA (2001) Recognition of double-stranded RNA and activation of NF-kB by Toll-like receptor 3. Nature 413: 732-738. (Pubitemid 33009951)
8. Kato H, Sato S, Yoneyama M, Yamamoto M, Uematsu S, et al. (2005) Cell-type specific involvement of RIG-I in antiviral response. Immunity 23: 19-28. (Pubitemid 41019654)
9. Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, et al. (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441: 101-105. (Pubitemid 43827959)
10. Pichlmair A, Schulz O, Tan CP, Näslund TI, Liljeström P, et al. (2006) RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 14: 997-1001. (Pubitemid 44749946)
11. Xu Y, Zhan Y, Lew AM, Naik SH, Kershaw MH (2007) Differential development of murine dendritic cells by GM-CSF versus Flt3 ligand has implications for inflammation and trafficking. J Immunol 179: 7577-7584.
12. Melkus MW, Estes JD, Padgett-Thomas A, Gatlin J, Denton PW, et al. (2006) Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1. Nat Med 12: 1316-1322. (Pubitemid 44706935)
13. Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, et al. (2004) Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8. Science 303: 1526-1529. (Pubitemid 38314424)
14. Di Pucchio T, Chatterjee B, Smed-Sörensen A, Clayton S, Palazzo A, et al. (2008) Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nat Immunol 9: 551-557. (Pubitemid 351560524)
15. Ishii KJ, Coban C, Kato H, Takahashi K, Torii Y, et al. (2006) A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat Immunol 7: 40-48. (Pubitemid 41823867)
16. Creagh EM, O'Neill LA (2006) TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity. Trends Immunol 27: 352-357.
17. Zinser E, Lechmann M, Golka A, Lutz MB, Steinkasserer A (2004) Prevention and treatment of experimental autoimmune encephalomyelitis by soluble CD83. J Exp Med 200: 345-351. (Pubitemid 39031253)
18. Hladik F, Sakchalathorn P, Ballweber L, Lentz G, Fialkow M, et al. (2007) Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1. Immunity 26: 257-270. (Pubitemid 46329434)
19. +-dendritic cells and Langerhans cells in HIV-1 transmission. Trends Mol Med 14: 12-19.
20. Geijtenbeek TB, van Kooyk Y (2003) Pathogens target DC-SIGN to influence their fate DC-SIGN functions as a pathogen receptor with broad specificity. APMIS 111: 698-714.
21. Marzi A, Möller P, Hanna SL, Harrer T, Eisemann J, et al. (2007) Analysis of the interaction of Ebola virus glycoprotein with DC-SIGN (dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin) and its homologue DC-SIGNR. J Infect Dis 196: 237-246.
22. Gringhuis SI, den Dunnen J, Litjens M, van Het Hof B, van Kooyk Y, et al. (2007) C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB. Immunity 26: 605-616. (Pubitemid 46756345)
23. Smith AL, Ganesh L, Leung K, Jongstra-Bilen J, Jongstra J, et al. (2007) Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells. J Exp Med 204: 421-430. (Pubitemid 46294556)
24. de Witte L, Abt M, Schneider-Schaulies S, van Kooyk Y, Geijtenbeek TB (2006) Measles virus targets DC-SIGN to enhance dendritic cell infection. J Virol 80: 3477-3486.
25. García-Piñeres AJ, Hildesheim A, Trivett M, Williams M, Wu L, et al. (2006) Role of DC-SIGN in the activation of dendritic cells by HPV-16 L1 virus-like particle vaccine. Eur J Immunol 36: 437-445. (Pubitemid 43257467)
26. Rappocciolo G, Jenkins FJ, Hensler HR, Piazza P, Jais M, et al. (2006) DC-SIGN is a receptor for human herpesvirus 8 on dendritic cells and macrophages. J Immunol 176: 1741-1749. (Pubitemid 43134319)
27. Yang ZY, Huang Y, Ganesh L, Leung K, Kong WP, et al. (2004) pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN. J Virol 78: 5642-5650. (Pubitemid 38661651)
28. Pöhlmann S, Zhang J, Baribaud F, Chen Z, Leslie GJ, et al. (2003) Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR. J Virol 77: 4070-40780. (Pubitemid 36350947)
29. Navarro-Sanchez E, Altmeyer R, Amara A, Schwartz O, Fieschi F, et al. (2003) Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses. EMBO Rep 4: 723-728. (Pubitemid 36974759)
30. Soilleux EJ, Coleman N (2001) Langerhans cells and the cells of Langerhans cell histiocytosis do not express DC-SIGN. Blood 98: 1987-1988.
31. de Witte L, Nabatov A, Pion M, Fluitsma D, de Jong MA, et al. (2007) Langerin is a natural barrier to HIV-1 transmission by Langerhans cells. Nat Med 3: 367-371. (Pubitemid 46376681)
32. Mahnke K, Guo M, Lee S, Sepulveda H, Swain SL, Nussenzweig M, Steinman RM (2000) The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J Cell Biol 151: 673-684. (Pubitemid 30828145)
33. Bozzacco L, Trumpfheller C, Siegal FP, Mehandru S, Markowitz M, et al. (2007) DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes. Proc Natl Acad Sci U S A 23: 1289-1294. (Pubitemid 46183997)
34. Bousarghin L, Hubert P, Franzen E, Jacobs N, Boniver J, Delvenne P (2005) Human papillomavirus 16 virus-like particles use heparan sulfates to bind dendritic cells and colocalize with langerin in Langerhans cells. J Gen Virol 86: 1297-1305. (Pubitemid 40613246)
35. Da Silva DM, Fausch SC, Verbeek JS, Kast WM (2007) Uptake of human papillomavirus virus-like particles by dendritic cells is mediated by Fcgamma receptors and contributes to acquisition of T cell immunity. J Immunol 178: 7587-7597.
36. Lambert AA, Gilbert C, Richard M, Beaulieu AD, Tremblay MJ (2008) The Ctype lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways. Blood 112: 1299-1307.
37. Münch J, Rücker E, Ständker L, Adermann K, Goffinet C, et al. (2007) Semen-derived amyloid fibrils drastically enhance HIV infection. Cell 131: 1059-1071. (Pubitemid 350235017)
38. Sevilla N, McGavern DB, Teng C, Kunz S, Oldstone MBA (2004) Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion. J Clin Invest 113: 737-745. (Pubitemid 38544167)
39. Hodges A, Sharrocks K, Edelmann M, Baban D, Moris A, et al. (2007) Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication. Nat Immunol 8: 569-577. (Pubitemid 46785120)
40. Bueno SM, González PA, Pacheco R, Leiva ED, Cautivo KM, et al. (2008) Host immunity during RSV pathogenesis. Int Immunopharmacol 8: 1320-1329.
41. Barends M, de Rond LG, Dormans J, van Oosten M, Boelen A, et al. (2004) Respiratory syncytial virus, pneumonia virus of mice, and influenza A virus differently affect respiratory allergy in mice. Clin Exp Allergy 34: 488-496. (Pubitemid 38373014)
42. Bueno SM, González PA, Cautivo KM, Mora JE, Leiva ED, et al. (2008) Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG. Proc Natl Acad Sci U S A 105: 20822-20827.
43. Lockridge KM, Zhou SS, Kravitz RH, Johnson JL, Sawai ET, et al. (2000) Primate cytomegaloviruses encode and express an IL-10-like protein. Virology 268: 272-280.
44. Wakkach A, Fournier N, Brun V, Breittmayer JP, Cottrez F, et al. (2003) Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18: 605-617. (Pubitemid 36588578)
45. Saito K, Ait-Goughoulte M, Truscott SM, Meyer K, Blazevic A, et al. (2008) Hepatitis C virus inhibits cell surface expression of HLA-DR, prevents dendritic cell maturation, and induces interleukin-10 production. J Virol 82: 3320-3328.
46. Shishkova Y, Harms H, Krohne G, Avota E, Schneider-Schaulies S (2007) Immune synapses formed with measles virus-infected dendritic cells are unstable and fail to sustain T cell activation. Cell Microbiol 9: 1974-1986. (Pubitemid 47087088)
47. González PA, Prado CE, Leiva ED, Carreño LJ, Bueno SM, et al. (2008) Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells. Proc Natl Acad Sci U S A 105: 14999-15004.
48. Mikloska Z, Bosnjak L, Cunningham AL (2001) Immature monocyte derived dendritic cells are productively infected with herpes simplex virus type 1. J Virol 75: 5958-5964. (Pubitemid 32553126)
49. Fernandez-Sesma A, Marukian S, Ebersole BJ, Kaminski D, Park MS, et al. (2006) Influenza virus evades innate and adaptive immunity via the NS1 protein. J Virol 80: 6295-6304. (Pubitemid 43927432)
50. Yao Y, Li P, Singh P, Thiele AT, Wilkes DS, et al. (2007) Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II. Cell Immunol 246: 92-102. (Pubitemid 47301780)
51. Kittan NA, Bergua A, Haupt S, Donhauser N, Schuster P, et al. (2007) Impaired plasmacytoid dendritic cell innate immune responses in patients with herpes virus-associated acute retinal necrosis. J Immunol 179: 4219-4230.
52. Pichyangkul S, Endy TP, Kalayanarooj S, Nisalak A, Yongvanitchit K, et al. (2003) A blunted blood plasmacytoid dendritic cell response to an acute systemic viral infection is associated with increased disease severity. J Immunol 171: 5571-5578. (Pubitemid 37432848)
53. Donaghy H, Pozniak A, Gazzard B, Qazi N, Gilmour J, et al. (2001) Loss of blood CD11c(+) myeloid and CD11c(2) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load. Blood 98: 2574-2576.
54. Smit JJ, Lindell DM, Boon L, Kool M, Lambrecht BN, Lukacs NW (2008) The balance between plasmacytoid DC versus conventional DC determines pulmonary immunity to virus infections. PLoS ONE 3: e1720. doi:10.1371/journal.pone. 0001720. (Pubitemid 351891291)
55. Dolganiuc A, Chang S, Kodys K, Mandrekar P, Bakis G, et al. (2006) Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection. J Immunol 15: 6758-6768. (Pubitemid 44715040)
56. Dillon SM, Robertson KB, Pan SC, Mawhinney S, Meditz AL, et al. (2008) Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection. J Acquir Immune Defic Syndr 48: 1-12. (Pubitemid 351600852)
57. Mandl JN, Barry AP, Vanderford TH, Kozyr N, Chavan R, et al. (2008) Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Nat Med 14: 1077-1087.
58. van Rijt LS, van Kessel CH, Boogaard I, Lambrecht BN (2005) Respiratory viral infections and asthma pathogenesis: a critical role for dendritic cells? J Clin Virol 34: 161-169.
59. Gill MA, Palucka AK, Barton T, Ghaffar F, Jafri H, et al. (2005) Mobilization of plasmacytoid and myeloid dendritic cells to mucosal sites in children with respiratory syncytial virus and other viral respiratory infections. J Infect Dis 191: 1105-1115. (Pubitemid 40404369)
60. Grayson MH, Cheung D, Rohlfing MM, Kitchens R, Spiegel DE, et al. (2007) Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia. J Exp Med 204: 2759-2769. (Pubitemid 350044797)
61. Boonnak K, Slike BM, Burgess TH, Mason RM, Wu SJ, et al. (2008) Role of dendritic cells in antibody dependent enhancement of dengue infection. J Virol 82: 3939-3951.
62. Kwan WH, Helt AM, Marañón C, Barbaroux JB, Hosmalin A, et al. (2005) Dendritic cell precursors are permissive to dengue virus and human immunodeficiency virus infection. J Virol 79: 7291-7299. (Pubitemid 40756764)
63. Novak N, Peng WM (2005) Dancing with the enemy: the interplay of herpes simplex virus with dendritic cells. Clin Exp Immunol 142: 405-410. (Pubitemid 41719834)
64. Kummer M, Turza NM, Muhl-Zurbes P, Lechmann M, Boutell C, et al. (2007) Herpes simplex virus type 1 induces CD83 degradation in mature dendritic cells with immediate-early kinetics via the cellular proteasome. J Virol 81: 6326-6338. (Pubitemid 46878039)
65. Benedict CA, Loewendorf A, Garcia Z, Blazar BR, Janssen EM (2008) Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway. J Immunol 180: 4836-4847.
66. Kvale EØ, Dalgaard J, Lund-Johansen F, Rollag H, Farkas L, et al. (2006) CD11c+ dendritic cells and plasmacytoid DCs are activated by human cytomegalovirus and retain efficient T cell-stimulatory capability upon infection. Blood 107: 2022-2029. (Pubitemid 43289386)
67. Granelli-Piperno A, Shimeliovich I, Pack M, Trumpfheller C, Steinman RM (2006) HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood. J Immunol 176: 991-998. (Pubitemid 43099698)
68. Cavrois M, Neidleman J, Greene W (2008) The Achilles heel of the Trojan Horse model of HIV-1 trans-infection. PLoS Pathog 4: e1000051. doi:10.1371/journal.ppat.1000051. (Pubitemid 351930620)
69. Puigdomenech I, Massanella M, Izquierdo-Useros N, Ruiz-Hernandez R, Curriu M, et al. (2008) HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4. Retrovirology 5: 32. (Pubitemid 351619159)
70. Izquierdo-Useros N, Blanco J, Erkizia I, Fernández-Figueras MT, Borràs FE, et al. (2007) Maturation of blood-derived dendritic cells enhances human immunodeficiency virus type 1 capture and transmission. J Virol 81: 7559-7570.
71. Frank I, Piatak M Jr, Stoessel H, Romani N, Bonnyay D, et al. (2002) Infectious and whole inactivated simian immunodeficiency viruses interact similarly with primate dendritic cells (DCs): differential intracellular fate of virions in mature and immature DCs. J Virol 76: 2936-2951. (Pubitemid 34184879)
72. Freer G, Matteucci D, Mazzetti P, Tarabella F, Catalucci V, et al. (2007) Effects of feline immunodeficiency virus on feline monocyte-derived dendritic cells infected by spinoculation. J Gen Virol 88: 2574-2582. (Pubitemid 47323905)
73. Ceccaldi PE, Delebecque F, Prevost MC, Moris A, Abastado JP, et al. (2006) DC-SIGN facilitates fusion of dendritic cells with human T-cell leukemia virus type 1-infected cells. J Virol 80: 4771-4780.
74. Jones KS, Petrow-Sadowski C, Huang YK, Bertolette DC, Ruscetti FW (2008) Cell-free HTLV-1 infects dendritic cells leading to transmission and transformation of CD4(+) T cells. Nat Med 14: 429-436.
75. Cormier EG, Durso RJ, Tsamis F, Boussemart L, Manix C, et al. (2004) L-SIGN (CD209L) and DC-SIGN (CD209) mediate transinfection of liver cells by hepatitis C virus. Proc Natl Acad Sci U S A 101: 14067-14072. (Pubitemid 39305031)
76. de Witte L, de Vries RD, van der Vlist M, Yüksel S, Litjens M, et al. (2008) DCSIGN and CD150 have distinct roles in transmission of measles virus from dendritic cells to T-lymphocytes. PLoS Pathog 4: e1000049. doi:10.1371/journal.ppat.1000049. (Pubitemid 351631073)
77. Tacken PJ, de Vries IJ, Torensma R, Figdor CG (2007) Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat Rev Immunol 7: 790-802. (Pubitemid 47480309)
78. Andrieu JM, Lu W (2007) A dendritic cell-based vaccine for treating HIV infection: background and preliminary results. J Intern Med 261: 123-131.
79. Connolly NC, Whiteside TL, Wilson C, Kondragunta V, Rinaldo CR, et al. (2008) Therapeutic immunization with human immunodeficiency virus type 1 (HIV-1) peptide-loaded dendritic cells is safe and induces immunogenicity in HIV-1-infected individuals. Clin Vaccine Immunol 15: 284-292. (Pubitemid 352025534)
80. Santin AD, Bellone S, Palmieri M, Zanolini A, Ravaggi A, et al. (2008) Human papillomavirus type 16 and 18 E7-pulsed dendritic cell vaccination of stage IB or IIA cervical cancer patients: a phase I escalating-dose trial. J Virol 82: 1968-1979. (Pubitemid 351206942)
81. Freer G, Matteucci D, Mazzetti P, Bozzacco L, Bendinelli M (2005) Generation of feline dendritic cells derived from peripheral blood monocytes for in vivo use. Clin Diag Lab Immunol 12: 1202-1208. (Pubitemid 41475829)
82. Freer G, Matteucci D, Mazzetti P, Tarabella F, Catalucci V, et al. (2008) Evaluation of feline monocyte-derived dendritic cells loaded with internally inactivated virus as a vaccine against feline immunodeficiency virus. Clin Vaccine Immunol 15: 452-459. (Pubitemid 351967063)
83. Freer G, Matteucci D, Mazzetti P, Tarabella F, Ricci E, et al. (2008) Immunotherapy with internally inactivated virus loaded dendritic cells boosts cellular immunity but does not affect feline immunodeficiency virus infection course. Retrovirology 5: 33. (Pubitemid 351639512)
84. Idoyaga J, Cheong C, Suda K, Suda N, Kim JY, et al. (2008) Cutting edge: Langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo. J Immunol 180: 3647-3650.
85. Gurer C, Strowig T, Brilot F, Pack M, Trumpfheller C, et al. (2008) Targeting the nuclear antigen 1 of Epstein Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Blood 112: 1231-1239.
86. Eisenächer K, Steinberg C, Reindl W, Krug A (2007) The role of viral nucleic acid recognition in dendritic cells for innate and adaptive antiviral immunity. Immunobiology 212: 701-714.
87. Hinton HJ, Jegerlehner A, Bachmann MF (2008) Pattern recognition by B cells: the role of antigen repetitiveness versus Toll-like receptors. Curr Top Microbiol Immunol 319: 1-15.