Thermosensitive micelles based on folate-conjugated poly(N-vinylcaprolactam)-block-poly(ethylene glycol) for tumor-targeted drug delivery

Macromolecular Bioscience

Volumn 9, Issue 8, 2009, Pages 744-753

  Prabaharan, Mani ^a   Grailer, Jamison J ^b   Steeber, Douglas A ^b   Gong, Shaoqin ^a  

^a University of Wisconsin Milwaukee   (United States)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

Core shell polymers; Drug delivery systems; Micelles; Synthesis; Thermosensitive

Indexed keywords

ANTICANCER DRUG; AQUEOUS SOLUTIONS; CANCER CELLS; CONTROLLED RELEASE; CORE/SHELL POLYMERS; DRUG DELIVERY SYSTEMS; FOLIC ACIDS; HUMAN ENDOTHELIAL CELLS; MAMMARY CARCINOMA CELL; RECEPTOR-MEDIATED ENDOCYTOSIS; RELEASE PROFILES; SELF-ASSEMBLED; STABLE MICELLES; SYNTHESIS; TARGETED DRUG DELIVERY; THERMOSENSITIVE; THERMOSENSITIVE MICELLES;

BLOCK COPOLYMERS; CELL CULTURE; CELL MEMBRANES; CYTOTOXICITY; DRUG DELIVERY; ENDOTHELIAL CELLS; ETHYLENE; ETHYLENE GLYCOL; MICELLES; ORGANIC ACIDS; ORGANIC POLYMERS; POLYETHYLENE OXIDES; POLYMERS;

POLYETHYLENE GLYCOLS;

COPOLYMER; FLUOROURACIL; FOLATE RECEPTOR; FOLIC ACID; POLY(N VINYLCAPROLACTAM) BLOCK POLY(ETHYLENE GLYCOL); UNCLASSIFIED DRUG;

ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER THERAPY; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG TARGETING; ENDOCYTOSIS; ENDOTHELIUM CELL; HEAT SENSITIVITY; HUMAN; HUMAN CELL; MICELLE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PARTICLE SIZE; SLOW DRUG RELEASE;

ANIMALS; ANTINEOPLASTIC AGENTS; CAPROLACTAM; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; FOLIC ACID; HUMANS; MICE; MICELLES; POLYETHYLENE GLYCOLS; POLYMERS; SPECIES SPECIFICITY; TEMPERATURE;

EID: 70049115538     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.200800366     Document Type: Article

References (35)

1. V. P. Torchilin, J. Controlled Release 2001, 73, 137.
2. G. S. Kwon, K. Kataoka, Adv. Drug. Delivery Rev. 1995, 16, 295.
3. S. Q. Liua, Y. W. Tong, Y. Y. Yang, Biomaterials 2005, 26, 5064.
4. S. Majumdar, S. Duvvuri, A. K. Mitra, Adv. Drug Delivery Rev. 2004, 56, 1437.
5. Z. M. Qian, H. Li, H. Sun, K. Ho, Pharm. Rev. 2002, 54, 561.
6. P. Sapra, T. M. Allen, Prog. Lipid Res. 2003, 42, 439.
7. G. M. Dubowchik, M. A. Walker, Pharm. Therapeut. 1999, 83, 67.
8. K. Na, T. B. Lee, K. Park, E. Shin, Y. Lee, H. Choi, Eur. J. Pharm. Sci. 2003, 18, 165.
9. C. P. Leamon, J. A. Reddy, Adv. Drug Delivery Rev. 2004, 56, 1127.
10. E. K. Park, S. Y. Kim, S. B. Lee, Y. M. Lee, J. Controlled Release 2005, 109, 158.
11. Y. Lu, P. S. Low, J. Controlled Release 2003, 91, 17.
12. Y. Lu, E. Sega, C. P. Low, Adv. Drug Delivery Rev. 2004, 56, 1161.
13. H. S. Yoo, T. G. Park, J. Controlled Release 2004, 96, 273.
14. J. A. Hubbell, Science 2003, 300, 595.
15. F. Kohori, K. Sakai, T. Aoyagi, M. Yokoyama, M. Yamato, Y. Sakurai, T. Okano, J. Controlled Release 1999, 16, 195.
16. A. Laukkanen, A. L. Valtola, F. Winnik, H. Tenhu, Macromolecules 2004, 37, 2268.
17. I. Y. Galaev, B. Mattiasson, Trends Biotechnol. 1999, 17, 335.
18. M. Sugimoto, M. Morimoto, H. Sashiwa, H. Saimoto, Y. Shigemasa, Carbohyd. Polym. 1998, 36, 49.
19. G. Pasut, F. M. Veronese, Prog. Polym. Sci. 2007, 32, 933.
20. P. Chan, M. Kurisawa, J. E. Chung, Y. Y. Yang, Biomaterials 2007, 28, 540.
21. L. A. Tziveleka, C. Kontoyianni, Z. Sideratou, D. Tsiourvas, C. M. Paleos, Macromol. Biosci. 2006, 6, 161.
22. J. H. Van Steenis, E. M. Van Maarseveen, F. J. Verbaan, R. Verrijk, D. J. A. Crommelin, G. Storm, J. Controlled Release 2003, 87, 167.
23. M. Prabaharan, J. J. Grailer, D. A. Steeber, S. Gong, Macromol. Biosci. 2008, 8, 843.
24. R. Savic, L. Luo, A. Eisenberg, D. Maysinger, Science 2003, 300, 615.
25. J. Ren, M. Jia, T. Ren, W. Yuan, Q. Tan, Mater. Lett. 2008, 62, 4425.
26. T. Mosmann, J. Immunol. Methods 1983, 65, 55.
27. C. J. S. Edgell, C. C. McDonald, J. B. Graham, Proc. Natl. Acad. Sci. USA 1983, 80, 3734.
28. D. Dube, M. Francis, J. C. Leroux, F. M. Winnik, Bioconjugate Chem. 2002, 13, 685.
29. D. Wang, Z. Peng, X. Liu, Z. Tong, C. Wang, B. Ren, Eur. Polym. J. 2007, 43, 2799.
30. K. C. Dowling, J. K. Thomas, Macromolecules 1990, 23, 1059.
31. G. S. Kwon, M. Naito, M. Yokoyama, T. Okano, Y. Sakurai, K. Kataoka, Langmuir 1993, 9, 945.
32. C. Allen, D. Maysinger, A. Eisenberg, Colloids Surf. B: Biointerfaces 1999, 16, 3.
33. E. Blanco, E. A. Bey, Y. Dong, B. D. Weinberg, D. M. Sutton, D. A. Boothman, J. Gao, J. Controlled Release 2007, 122, 365.
34. R. J. Lee, P. S. Low, J. Biol. Chem. 1994, 269, 3198.
35. K. S. Soppimath, L. H. Liu, W. Y. Seow, S. Q. Liu, R. Powell, P. Chen, Y. Y. Yang, Adv. Funct. Mater. 2007, 17, 355.