A mammalianized synthetic nitroreductase gene for high-level expression

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Grohmann, Maik ^a,b,c   Paulmann, Nils ^a,b   Fleischhauer, Sebastian ^a,d   Vowinckel, Jakob ^a,b   Priller, Josef ^c   Walther, Diego J ^a  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d BEUTH UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; CYTOPLASM PROTEIN; GREEN FLUORESCENT PROTEIN; MYC PROTEIN; NITROREDUCTASE; SYNTHETIC DNA; 5-(1-AZIRIDINYL)-2,4-DINITROBENZAMIDE; ANTINEOPLASTIC AGENT; AZIRIDINE DERIVATIVE; PRODRUG; TRETAZICAR;

ANIMAL CELL; ARTICLE; BYSTANDER EFFECT; CANCER INHIBITION; CELL PROLIFERATION; CODON USAGE; CONTROLLED STUDY; CYTOTOXICITY; DNA MODIFICATION; DRUG SCREENING; EMBRYO; ENZYME MECHANISM; EUKARYOTE; GENE DIRECTED ENZYME PRODRUG THERAPY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MAMMAL CELL; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PROKARYOTE; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; SENSITIZATION; SPECIES COMPARISON; TRANSLATION REGULATION; TUMOR CELL LINE; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; BIOTRANSFORMATION; CODON; DRUG EFFECT; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN ENGINEERING;

AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; AZIRIDINES; BASE SEQUENCE; BIOTRANSFORMATION; CELL LINE, TUMOR; CELL PROLIFERATION; CODON; GENE EXPRESSION; GENES, SYNTHETIC; HUMANS; MOLECULAR SEQUENCE DATA; NITROREDUCTASES; PRODRUGS; PROTEIN ENGINEERING;

EID: 70049098539     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-301     Document Type: Article

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