Preparation of the oral self-microemulsifying drug delivery system of GBE50

Yaoxue Xuebao

Volumn 44, Issue 7, 2009, Pages 803-808

  Xiong, Ying ^a,b   Liu, Qi De ^b   Lai, Le ^a   Chen, Jian Hai ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Bioavailability; Formulation; GBE50; Self microemulsifying drug delivery system

Indexed keywords

EMULSIFYING AGENT; GINKGO BILOBA EXTRACT; WATER;

AREA UNDER THE CURVE; ARTICLE; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG SOLUBILITY; DRUG STABILITY; MAXIMUM PLASMA CONCENTRATION; MICROEMULSION; PARTICLE SIZE; PHARMACOKINETICS; PLASMA CONCENTRATION-TIME CURVE; TIME TO MAXIMUM PLASMA CONCENTRATION;

BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; DRUGS, CHINESE HERBAL; GINKGOLIDES; TECHNOLOGY, PHARMACEUTICAL;

EID: 70049093306     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Constantinides PP. Lipid microemulsions for improving drug dissolution and oral absorption physical and biopharm aceutical aspects [J]. Pharm Res, 1995, 12: 1561-1572.
2. Gursoy RN, Benita S. Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs [J]. Biomed Pharmacother, 2004, 58: 173-182. (Pubitemid 38479922)
3. Ministry of Health of the People's Republic of China. Standards of Health Ministry [S]. WS3-227 (Z-028)-2002 (Z): 40-44.
4. Pan GL, Jia XB, Wei HH, et al. Comparison among several preparation methods for pseudo-ternary phase diagrams of pharmaceutical microemulsions [J]. J China Pharm, 2006, 17: 21-23.
5. LU JL, Liu ZH, Wang JC, et al. Preparation of 9-nitrocamptothecin self-emulsification microemulsion and in vitro cytotoxicity evaluation [J]. Chin J New Drugs, 2008, 17: 861-865.
6. Cui SM, Zhao CS, He ZG Assessment of pueraria lobata isoflavone with self-microemulsifying drug delivery systems in vitro and in vivo [J]. J Chin Med Mater, 2007, 30: 684-687.
7. Zhou XT, Wang J, Wang Y, et al. Design and in vitro evaluation of self-microemulsifying drug delivery systems for piroxicam [J]. Acta Pharm Sin, 2008, 43: 415-420.
8. China Pharmacopoeia Committee. Pharmacopoeia of the People's Republic of China [M]. 2005 ed. Beijing: Chemical Industry Press, 2005: Appendix XC, XIX C.
9. Wang FM, Wu MZ, Zhou L, et al. Ginkgo flavonoids in plasma by HPLC method studies [J]. China J Chin Mater Med, 2003, 28: 279-281.
10. Yang YJ, Ping QN, Song YM. Improvement of the dissolution rate of Ginkgo biloba tablets by using solid dispersion methods [J]. Chin J New Drugs, 2004, 13: 521-524.