The MrpA, MrpB and MrpD subunits of the Mrp antiporter complex in bacillus subtilis contain membrane-embedded and essential acidic residues

Microbiology

Volumn 155, Issue 7, 2009, Pages 2137-2147

  Kajiyama, Yusuke ^a   Otagiri, Masato ^a   Sekiguchi, Junichi ^b   Kudo, Toshiaki ^a,c   Kosono, Saori ^a  

^a RIKEN   (Japan)

^b SHINSHU UNIVERSITY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; CARRIER PROTEIN; GLUTAMINE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN A; MULTIDRUG RESISTANCE PROTEIN B; MULTIDRUG RESISTANCE PROTEIN D; MULTIDRUG RESISTANCE PROTEIN E; MULTIDRUG RESISTANCE PROTEIN F; PROTEIN MBH; PROTEIN NUO; SODIUM ION; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; CONTROLLED STUDY; ESCHERICHIA COLI; ION TRANSPORT; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN QUATERNARY STRUCTURE; SITE DIRECTED MUTAGENESIS; SODIUM TRANSPORT;

AMINO ACID SEQUENCE; AMINO ACIDS, ACIDIC; BACILLUS SUBTILIS; BACTERIAL PROTEINS; CELL MEMBRANE; CONSERVED SEQUENCE; ESCHERICHIA COLI; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; SODIUM; SODIUM-HYDROGEN ANTIPORTER;

BACILLUS SUBTILIS; ESCHERICHIA COLI; NEGIBACTERIA;

EID: 69949185951     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.025205-0     Document Type: Article

References (34)

1. Abramson, J., Smirnova, I., Kasho, V., Verner, G., Kaback, H. R. & Iwata, S. (2003). Structure and mechanism of the lactose permease of Escherichia coli. Science 301, 610-615.
2. Bayer, A. S., McNamara, P., Yeaman, M. R., Lucindo, N., Jones, T., Cheung, A. L., Sahl, H. G. & Proctor, R. A. (2006). Transposon disruption of the complex I NADH oxidoreductase gene (snoD) in Staphylococcus aureus is associated with reduced susceptibility to the microbicidal activity of thrombin-induced platelet microbicidal protein 1. J Bacteriol 188, 211-222.
3. + and adaptation to alkaline pH in the cyanobacterium Anabaena sp. PCC7120. Microbiology 151, 1671-1682.
4. Friedrich, T. & Scheide, D. (2000). The respiratory complex I of bacteria, archaea and eukarya and its module common with membrane-bound multisubunit hydrogenases. FEBS Lett 479, 1-5.
5. + antiporter from Staphylococcus aureus. J Bacteriol 180, 6642-6648.
6. + antiporter and insights into mechanism of action and regulation by pH. Nature 435, 1197-1202.
7. + antiporter (NhaA) from Escherichia coli. FEBS Lett 363, 264-268.
8. + antiporters of Bacillus exhibit characteristics that are unanticipated for completely secondary active transporters. FEBS Lett 496, 117-120.
9. + antiporter in Bacillus subtilis. J Bacteriol 189, 7511-7514.
10. + antiporter and a molybdate transporter are essential for arsenite oxidation in Agrobacterium tumefaciens. J Bacteriol 188, 1577-1584.
11. + antiporter gene which is important for pH homeostasis of alkaliphilic Bacillus sp. C-125. Biochim Biophys Acta 1409, 171-175.
12. + antiporter, ShaA, is required for initiation of sporulation in Bacillus subtilis. J Bacteriol 182, 898-904.
13. Kosono, S., Haga, K., Tomizawa, R., Kajiyama, Y., Hatano, K., Takeda, S., Wakai, Y., Hino, M. & Kudo, T. (2005). Characterization of a multigene-encoded sodium/hydrogen antiporter (Sha) from Pseudomonas aeruginosa: its involvement in pathogenesis. J Bacteriol 187, 5242-5248.
14. + antiporter in Bacillus subtilis. Biochim Biophys Acta 1758, 627-635.
15. Mathiesen, C. & Haegerhaell, C. (2003). The 'antiporter module' of respiratory chain complex I includes the MrpC/NuoK subunit - a revision of the modular evolution scheme. FEBS Lett 549, 7-13.
16. +-ATPase from Ilyobacter tartaricus. Science 308, 659-662.
17. +-translocating function retained. Proc Natl Acad Sci U S A 87, 4900-4904.
18. Morimoto, T., Loh, P. C., Hirai, T., Asai, K., Kobayashi, K., Moriya, S. & Ogasawara, N. (2002). Six GTP-binding proteins of the Era/ Obg family are essential for cell growth in Bacillus subtilis. Microbiology 148, 3539-3552.
19. + antiporter of alkaliphilic Bacillus and formation of hetero-oligomeric Mrp complexes. J Bacteriol 190, 4162-4172.
20. +-ATPase from Enterococcus hirae. Science 308, 654-659.
21. + exchanger. Eur J Biochem 268, 4674-4685.
22. +-ATPase. Proc Natl Acad Sci U S A 88, 1938-1942.
23. + antiporter of Vibrio parahaemolyticus. Biochem Biophys Res Commun 222, 774-779.
24. Pornillos, O., Chen, Y. J., Chen, A. P. & Chang, G. (2005). X-ray structure of the EmrE multidrug transporter in complex with a substrate. Science 310, 1950-1953.
25. + efflux system. Mol Microbiol 28, 1091-1101.
26. Saier, M. H., Jr (2000). A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol Mol Biol Rev 64, 354-411.
27. Swartz, T. H., Ikewada, S., Ishikawa, O., Ito, M. & Krulwich, T. A. (2005a). The Mrp system: a giant among monovalent cation/proton antiporters? Extremophiles 9, 345-354.
28. + antiporter increases the activity of the malate: quinone oxidoreductase of an Escherichia coli respiratory mutant. J Bacteriol 187, 388-391.
29. +-translocating ATPase in Enterococcus hirae. Biosci Biotechnol Biochem 63, 1125-1129.
30. Thompson, J. D., Gibson, T. J., Plewniak, F., Jeanmougin, F. & Higgins, D. G. (1997). The CLUSTAL_X Windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25, 4876-4882.
31. Torres-Bacete, J., Nakamaru-Ogiso, E., Matsuno-Yagi, A. & Yagi, T. (2007). Characterization of the NuoM (ND4) subunit in Escherichia coli NDH-1: conserved charged residues essential for energy-coupled activities. J Biol Chem 282, 36914-36922.
32. Yamashita, S., Yoshikawa, H., Kawamura, F., Takahashi, H., Yamamoto, T., Kobayashi, Y. & Saito, H. (1986). The effect of spo0 mutations on the expression of spo0A- and spo0F-lacZ fusions. Mol Gen Genet 205, 28-33.
33. --dependent neurotransmitter transporters. Nature 437, 215-223.
34. + sensitivity compared to other deletion mutants in the Bacillus subtilis sodium/hydrogen antiporter (Sha) system. J Biosci Bioeng 95, 306-309.