Ecdysone Receptor Acts in fruitless- Expressing Neurons to Mediate Drosophila Courtship Behaviors

Current Biology

Volumn 19, Issue 17, 2009, Pages 1447-1452

  Dalton, Justin E ^a   Lebo, Matthew S ^a   Sanders, Laura E ^a   Sun, Fengzhu ^a   Arbeitman, Michelle N ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

CELLBIO

Indexed keywords

DROSOPHILA PROTEIN; ECDYSONE RECEPTOR; ECDYSONE RECEPTOR A, INSECT; FRU PROTEIN, DROSOPHILA; INSECT PROTEIN; NERVE PROTEIN; STEROID RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL; ARTICLE; DROSOPHILA MELANOGASTER; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HISTOLOGY; MALE; METABOLISM; METAMORPHOSIS; OLFACTORY RECEPTOR; PHYSIOLOGY; SEXUAL BEHAVIOR;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSECT PROTEINS; MALE; METAMORPHOSIS, BIOLOGICAL; NERVE TISSUE PROTEINS; OLFACTORY RECEPTOR NEURONS; RECEPTORS, STEROID; SEXUAL BEHAVIOR, ANIMAL; TRANSCRIPTION FACTORS;

DROSOPHILA MELANOGASTER;

EID: 69949164571     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2009.06.063     Document Type: Article

References (30)

1. Villella A., and Hall J.C. Neurogenetics of courtship and mating in Drosophila. Adv. Genet. 62 (2008) 67-184
2. Dauwalder B., Tsujimoto S., Moss J., and Mattox W. The Drosophila takeout gene is regulated by the somatic sex-determination pathway and affects male courtship behavior. Genes Dev. 16 (2002) 2879-2892
3. Drapeau M.D., Radovic A., Wittkopp P.J., and Long A.D. A gene necessary for normal male courtship, yellow, acts downstream of fruitless in the Drosophila melanogaster larval brain. J. Neurobiol. 55 (2003) 53-72
4. Goldman T.D., and Arbeitman M.N. Genomic and functional studies of Drosophila sex hierarchy regulated gene expression in adult head and nervous system tissues. PLoS Genet 3 (2007) e216
5. Lee G., Bahn J.H., and Park J.H. Sex- and clock-controlled expression of the neuropeptide F gene in Drosophila. Proc. Natl. Acad. Sci. USA 103 (2006) 12580-12585
6. Riddiford L.M., Cherbas P., and Truman J.W. Ecdysone receptors and their biological actions. Vitam. Horm. 60 (2000) 1-73
7. Cherbas L., Bogart K., Zhou Y., Cherbas P., and Andrews J. DGRC-2: Spotted oligonucleotide transcriptome microarrays for the Drosophila community. CGB Technical Report 2006-01 (2006) 1-12
8. Lebo M.S., Sanders L.E., Sun F., and Arbeitman M.N. Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. BMC Genomics 10 (2009) 80
9. Lee G., Foss M., Goodwin S.F., Carlo T., Taylor B.J., and Hall J.C. Spatial, temporal, and sexually dimorphic expression patterns of the fruitless gene in the Drosophila central nervous system. J. Neurobiol. 43 (2000) 404-426
10. Beckstead R.B., Lam G., and Thummel C.S. The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis. Genome Biol. 6 (2005) R99
11. Hoopfer E.D., Penton A., Watts R.J., and Luo L. Genomic analysis of Drosophila neuronal remodeling: a role for the RNA-binding protein Boule as a negative regulator of axon pruning. J. Neurosci. 28 (2008) 6092-6103
12. Li T.R., and White K.P. Tissue-specific gene expression and ecdysone-regulated genomic networks in Drosophila. Dev. Cell 5 (2003) 59-72
13. Truman J.W., Talbot W.S., Fahrbach S.E., and Hogness D.S. Ecdysone receptor expression in the CNS correlates with stage-specific responses to ecdysteroids during Drosophila and Manduca development. Development 120 (1994) 219-234
14. Kimura K., Hachiya T., Koganezawa M., Tazawa T., and Yamamoto D. Fruitless and doublesex coordinate to generate male-specific neurons that can initiate courtship. Neuron 59 (2008) 759-769
15. Manoli D.S., Foss M., Villella A., Taylor B.J., Hall J.C., and Baker B.S. Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour. Nature 436 (2005) 395-400
16. Stockinger P., Kvitsiani D., Rotkopf S., Tirian L., and Dickson B.J. Neural circuitry that governs Drosophila male courtship behavior. Cell 121 (2005) 795-807
17. Ganter G.K., Walton K.L., Merriman J.O., Salmon M.V., Brooks K.M., Maddula S., and Kravitz E.A. Increased male-male courtship in ecdysone receptor deficient adult flies. Behav. Genet. 37 (2007) 507-512
18. Kondoh Y., Kaneshiro K.Y., Kimura K., and Yamamoto D. Evolution of sexual dimorphism in the olfactory brain of Hawaiian Drosophila. Proc. Biol. Sci. 270 (2003) 1005-1013
19. Thummel C.S. Ecdysone-regulated puff genes 2000. Insect Biochem. Mol. Biol. 32 (2002) 113-120
20. Thummel C.S. Molecular mechanisms of developmental timing in C. elegans and Drosophila. Dev. Cell 1 (2001) 453-465
21. Liu E., and Restifo L.L. Identification of a broad complex-regulated enhancer in the developing visual system of Drosophila. J. Neurobiol. 34 (1998) 253-270
22. Restifo L.L., and White K. Mutations in a steroid hormone-regulated gene disrupt the metamorphosis of the central nervous system in Drosophila. Dev. Biol. 148 (1991) 174-194
23. Restifo L.L., and Merrill V.K. Two Drosophila regulatory genes, Deformed and the Broad-Complex, share common functions in development of adult CNS, head, and salivary glands. Dev. Biol. 162 (1994) 465-485
24. Datta S.R., Vasconcelos M.L., Ruta V., Luo S., Wong A., Demir E., Flores J., Balonze K., Dickson B.J., and Axel R. The Drosophila pheromone cVA activates a sexually dimorphic neural circuit. Nature 452 (2008) 473-477
25. Talbot W.S., Swyryd E.A., and Hogness D.S. Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms. Cell 73 (1993) 1323-1337
26. Colombani J., Bianchini L., Layalle S., Pondeville E., Dauphin-Villemant C., Antoniewski C., Carre C., Noselli S., and Leopold P. Antagonistic actions of ecdysone and insulins determine final size in Drosophila. Science 310 (2005) 667-670
27. Roignant J.Y., Carre C., Mugat B., Szymczak D., Lepesant J.A., and Antoniewski C. Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila. RNA 9 (2003) 299-308
28. Cherbas L., Hu X., Zhimulev I., Belyaeva E., and Cherbas P. EcR isoforms in Drosophila: Testing tissue-specific requirements by targeted blockade and rescue. Development 130 (2003) 271-284
29. Brown H.L., Cherbas L., Cherbas P., and Truman J.W. Use of time-lapse imaging and dominant negative receptors to dissect the steroid receptor control of neuronal remodeling in Drosophila. Development 133 (2006) 275-285
30. Robinow S., Talbot W.S., Hogness D.S., and Truman J.W. Programmed cell death in the Drosophila CNS is ecdysone-regulated and coupled with a specific ecdysone receptor isoform. Development 119 (1993) 1251-1259