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Volumn 4, Issue 8, 2009, Pages

Circadian dysregulation disrupts bile acid homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CARRIER PROTEIN; CHOLESTEROL 7ALPHA MONOOXYGENASE; FARNESOID X RECEPTOR; PER1 PROTEIN; PER2 PROTEIN; PROTEIN CAR; PROTEIN NTCP; RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DBP; UNCLASSIFIED DRUG; BILE ACID; CIRCADIAN RHYTHM SIGNALING PROTEIN; PER1 PROTEIN, MOUSE; PER2 PROTEIN, MOUSE;

EID: 69949164553     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006843     Document Type: Article
Times cited : (108)

References (62)
  • 1
    • 0037870773 scopus 로고    scopus 로고
    • Synchronization of the molecular clockwork by light- and food-related cues in mammals
    • Challet E, Caldelas I, Graff C, Pevet P (2003) Synchronization of the molecular clockwork by light- and food-related cues in mammals. Biol Chem 384: 711-719.
    • (2003) Biol Chem , vol.384 , pp. 711-719
    • Challet, E.1    Caldelas, I.2    Graff, C.3    Pevet, P.4
  • 2
    • 0033637383 scopus 로고    scopus 로고
    • Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
    • Damiola F, Le Minh N, Preitner N, Kornmann B, Fleury-Olela F, et al. (2000) Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev 14: 2950-2961.
    • (2000) Genes Dev , vol.14 , pp. 2950-2961
    • Damiola, F.1    Le Minh, N.2    Preitner, N.3    Kornmann, B.4    Fleury-Olela, F.5
  • 4
    • 0031831495 scopus 로고    scopus 로고
    • Persistence of metabolic rhythmicity during fasting and its entrainment by restricted feeding schedules in rats
    • Escobar C, Diaz-Munoz M, Encinas F, Aguilar-Roblero R (1998) Persistence of metabolic rhythmicity during fasting and its entrainment by restricted feeding schedules in rats. Am J Physiol 274: R1309-1316.
    • (1998) Am J Physiol , vol.274
    • Escobar, C.1    Diaz-Munoz, M.2    Encinas, F.3    Aguilar-Roblero, R.4
  • 5
    • 18444414586 scopus 로고    scopus 로고
    • Coordinated transcription of key pathways in the mouse by the circadian clock
    • Panda S, Antoch MP, Miller BH, Su AI, Schook AB, et al. (2002) Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 109: 307-320.
    • (2002) Cell , vol.109 , pp. 307-320
    • Panda, S.1    Antoch, M.P.2    Miller, B.H.3    Su, A.I.4    Schook, A.B.5
  • 6
    • 33751115468 scopus 로고    scopus 로고
    • Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man
    • Lundasen T, Galman C, Angelin B, Rudling M (2006) Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man. J Intern Med 260: 530-536.
    • (2006) J Intern Med , vol.260 , pp. 530-536
    • Lundasen, T.1    Galman, C.2    Angelin, B.3    Rudling, M.4
  • 7
    • 0015239513 scopus 로고
    • Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis
    • Shapiro DJ, Rodwell VW (1971) Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis. J Biol Chem 246: 3210-3216.
    • (1971) J Biol Chem , vol.246 , pp. 3210-3216
    • Shapiro, D.J.1    Rodwell, V.W.2
  • 8
    • 0015480730 scopus 로고
    • In vivo demonstration of the circadian thythm of cholesterol biosynthesis in the liver and intestine of the rat
    • Edwards PA, Muroya H, Gould RG (1972) In vivo demonstration of the circadian thythm of cholesterol biosynthesis in the liver and intestine of the rat. J Lipid Res 13: 396-401.
    • (1972) J Lipid Res , vol.13 , pp. 396-401
    • Edwards, P.A.1    Muroya, H.2    Gould, R.G.3
  • 9
    • 0027428137 scopus 로고
    • Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP
    • Lavery DJ, Schibler U (1993) Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP. Genes Dev 7: 1871-1884.
    • (1993) Genes Dev , vol.7 , pp. 1871-1884
    • Lavery, D.J.1    Schibler, U.2
  • 10
    • 0016737778 scopus 로고
    • Rat-liver cholesterol 7alpha-hydroxylase. 3. New results about its circadian rhythm
    • Gielen J, Van Cantfort J, Robaye B, Renson J (1975) Rat-liver cholesterol 7alpha-hydroxylase. 3. New results about its circadian rhythm. Eur J Biochem 55: 41-48.
    • (1975) Eur J Biochem , vol.55 , pp. 41-48
    • Gielen, J.1    Van Cantfort, J.2    Robaye, B.3    Renson, J.4
  • 11
    • 0028798317 scopus 로고
    • Synchronous circadian rhythms of mRNA levels and activities of cholesterol 7 alpha-hydroxylase in the rabbit and rat
    • Kai M, Eto T, Kondo K, Setoguchi Y, Higashi S, et al. (1995) Synchronous circadian rhythms of mRNA levels and activities of cholesterol 7 alpha-hydroxylase in the rabbit and rat. J Lipid Res 36: 367-374.
    • (1995) J Lipid Res , vol.36 , pp. 367-374
    • Kai, M.1    Eto, T.2    Kondo, K.3    Setoguchi, Y.4    Higashi, S.5
  • 12
    • 0017079867 scopus 로고
    • The role of glucocorticoids in the regulation of the diurnal rhythm of hepatic beta-hydroxy-beta-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase
    • Mitropoulos KA, Balasubramaniam S (1976) The role of glucocorticoids in the regulation of the diurnal rhythm of hepatic beta-hydroxy-beta-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase. Biochem J 160: 49-55.
    • (1976) Biochem J , vol.160 , pp. 49-55
    • Mitropoulos, K.A.1    Balasubramaniam, S.2
  • 13
    • 0025291713 scopus 로고
    • Circadian rhythms of biliary protein and lipid excretion in rats
    • Nakano A, Tietz PS, LaRusso NF (1990) Circadian rhythms of biliary protein and lipid excretion in rats. Am J Physiol 258: G653-659.
    • (1990) Am J Physiol , vol.258
    • Nakano, A.1    Tietz, P.S.2    LaRusso, N.F.3
  • 15
    • 19544375394 scopus 로고    scopus 로고
    • Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1
    • Alvarez L, Jara P, Sanchez-Sabate E, Hierro L, Larrauri J, et al. (2004) Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1. Hum Mol Genet 13: 2451-2460.
    • (2004) Hum Mol Genet , vol.13 , pp. 2451-2460
    • Alvarez, L.1    Jara, P.2    Sanchez-Sabate, E.3    Hierro, L.4    Larrauri, J.5
  • 16
    • 20844448737 scopus 로고    scopus 로고
    • A clinical-morphological study on cholestatic presentation of nonalcoholic fatty liver disease
    • Sorrentino P, Tarantino G, Perrella A, Micheli P, Perrella O, et al. (2005) A clinical-morphological study on cholestatic presentation of nonalcoholic fatty liver disease. Dig Dis Sci 50: 1130-1135.
    • (2005) Dig Dis Sci , vol.50 , pp. 1130-1135
    • Sorrentino, P.1    Tarantino, G.2    Perrella, A.3    Micheli, P.4    Perrella, O.5
  • 17
    • 33645509321 scopus 로고    scopus 로고
    • Farnesoid X receptor is essential for normal glucose homeostasis
    • Ma K, Saha PK, Chan L, Moore DD (2006) Farnesoid X receptor is essential for normal glucose homeostasis. J Clin Invest 116: 1102-1109.
    • (2006) J Clin Invest , vol.116 , pp. 1102-1109
    • Ma, K.1    Saha, P.K.2    Chan, L.3    Moore, D.D.4
  • 18
    • 32244447570 scopus 로고    scopus 로고
    • Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice
    • Zhang Y, Lee FY, Barrera G, Lee H, Vales C, et al. (2006) Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice. Proc Natl Acad Sci U S A 103: 1006-1011.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 1006-1011
    • Zhang, Y.1    Lee, F.Y.2    Barrera, G.3    Lee, H.4    Vales, C.5
  • 19
    • 33747154772 scopus 로고    scopus 로고
    • Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
    • Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, et al. (2006) Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 126: 789-799.
    • (2006) Cell , vol.126 , pp. 789-799
    • Bookout, A.L.1    Jeong, Y.2    Downes, M.3    Yu, R.T.4    Evans, R.M.5
  • 20
    • 33747157406 scopus 로고    scopus 로고
    • Nuclear receptor expression links the circadian clock to metabolism
    • Yang X, Downes M, Yu RT, Bookout AL, He W, et al. (2006) Nuclear receptor expression links the circadian clock to metabolism. Cell 126: 801-810.
    • (2006) Cell , vol.126 , pp. 801-810
    • Yang, X.1    Downes, M.2    Yu, R.T.3    Bookout, A.L.4    He, W.5
  • 21
    • 0033636789 scopus 로고    scopus 로고
    • Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
    • Lu TT, Makishima M, Repa JJ, Schoonjans K, Kerr TA, et al. (2000) Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol Cell 6: 507-515.
    • (2000) Mol Cell , vol.6 , pp. 507-515
    • Lu, T.T.1    Makishima, M.2    Repa, J.J.3    Schoonjans, K.4    Kerr, T.A.5
  • 22
    • 0033637121 scopus 로고    scopus 로고
    • A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
    • Goodwin B, Jones SA, Price RR, Watson MA, McKee DD, et al. (2000) A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol Cell 6: 517-526.
    • (2000) Mol Cell , vol.6 , pp. 517-526
    • Goodwin, B.1    Jones, S.A.2    Price, R.R.3    Watson, M.A.4    McKee, D.D.5
  • 23
    • 18444377348 scopus 로고    scopus 로고
    • Redundant pathways for negative feedback regulation of bile acid production
    • Wang L, Lee YK, Bundman D, Han Y, Thevananther S, et al. (2002) Redundant pathways for negative feedback regulation of bile acid production. Dev Cell 2: 721-731.
    • (2002) Dev Cell , vol.2 , pp. 721-731
    • Wang, L.1    Lee, Y.K.2    Bundman, D.3    Han, Y.4    Thevananther, S.5
  • 24
    • 0036086509 scopus 로고    scopus 로고
    • Loss of Nuclear Receptor SHP Impairs but Does Not Eliminate Negative Feedback Regulation of Bile Acid Synthesis
    • Kerr TA, Saeki S, Schneider M, Schaefer K, Berdy S, et al. (2002) Loss of Nuclear Receptor SHP Impairs but Does Not Eliminate Negative Feedback Regulation of Bile Acid Synthesis. Dev Cell 2: 713-720.
    • (2002) Dev Cell , vol.2 , pp. 713-720
    • Kerr, T.A.1    Saeki, S.2    Schneider, M.3    Schaefer, K.4    Berdy, S.5
  • 26
    • 27844546989 scopus 로고    scopus 로고
    • Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
    • Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, et al. (2005) Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab 2: 217-225.
    • (2005) Cell Metab , vol.2 , pp. 217-225
    • Inagaki, T.1    Choi, M.2    Moschetta, A.3    Peng, L.4    Cummins, C.L.5
  • 27
    • 0037663483 scopus 로고    scopus 로고
    • Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis
    • Holt JA, Luo G, Billin AN, Bisi J, McNeill YY, et al. (2003) Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. Genes Dev 17: 1581-1591.
    • (2003) Genes Dev , vol.17 , pp. 1581-1591
    • Holt, J.A.1    Luo, G.2    Billin, A.N.3    Bisi, J.4    McNeill, Y.Y.5
  • 28
    • 0034664729 scopus 로고    scopus 로고
    • Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
    • Sinal CJ, Tohkin M, Miyata M, Ward JM, Lambert G, et al. (2000) Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102: 731-744.
    • (2000) Cell , vol.102 , pp. 731-744
    • Sinal, C.J.1    Tohkin, M.2    Miyata, M.3    Ward, J.M.4    Lambert, G.5
  • 29
    • 0037184977 scopus 로고    scopus 로고
    • A web of circadian pacemakers
    • Schibler U, Sassone-Corsi P (2002) A web of circadian pacemakers. Cell 111: 919-922.
    • (2002) Cell , vol.111 , pp. 919-922
    • Schibler, U.1    Sassone-Corsi, P.2
  • 30
    • 6344221991 scopus 로고    scopus 로고
    • The mammalian circadian timing system: From gene expression to physiology
    • Gachon F, Nagoshi E, Brown SA, Ripperger J, Schibler U (2004) The mammalian circadian timing system: from gene expression to physiology. Chromosoma 113: 103-112.
    • (2004) Chromosoma , vol.113 , pp. 103-112
    • Gachon, F.1    Nagoshi, E.2    Brown, S.A.3    Ripperger, J.4    Schibler, U.5
  • 31
    • 33745329809 scopus 로고    scopus 로고
    • The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification
    • Gachon F, Olela FF, Schaad O, Descombes P, Schibler U (2006) The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab 4: 25-36.
    • (2006) Cell Metab , vol.4 , pp. 25-36
    • Gachon, F.1    Olela, F.F.2    Schaad, O.3    Descombes, P.4    Schibler, U.5
  • 32
    • 0035059442 scopus 로고    scopus 로고
    • Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus
    • Hara R, Wan K, Wakamatsu H, Aida R, Moriya T, et al. (2001) Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus. Genes Cells 6: 269-278.
    • (2001) Genes Cells , vol.6 , pp. 269-278
    • Hara, R.1    Wan, K.2    Wakamatsu, H.3    Aida, R.4    Moriya, T.5
  • 33
    • 0035910387 scopus 로고    scopus 로고
    • Entrainment of the circadian clock in the liver by feeding
    • Stokkan KA, Yamazaki S, Tei H, Sakaki Y, Menaker M (2001) Entrainment of the circadian clock in the liver by feeding. Science 291: 490-493.
    • (2001) Science , vol.291 , pp. 490-493
    • Stokkan, K.A.1    Yamazaki, S.2    Tei, H.3    Sakaki, Y.4    Menaker, M.5
  • 34
    • 0034730493 scopus 로고    scopus 로고
    • Resetting of circadian time in peripheral tissues by glucocorticoid signaling
    • Balsalobre A, Brown SA, Marcacci L, Tronche F, Kellendonk C, et al. (2000) Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science 289: 2344-2347.
    • (2000) Science , vol.289 , pp. 2344-2347
    • Balsalobre, A.1    Brown, S.A.2    Marcacci, L.3    Tronche, F.4    Kellendonk, C.5
  • 35
    • 0034687223 scopus 로고    scopus 로고
    • Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts
    • Balsalobre A, Marcacci L, Schibler U (2000) Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts. Curr Biol 10: 1291-1294.
    • (2000) Curr Biol , vol.10 , pp. 1291-1294
    • Balsalobre, A.1    Marcacci, L.2    Schibler, U.3
  • 36
    • 0035368681 scopus 로고    scopus 로고
    • Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock
    • Zheng B, Albrecht U, Kaasik K, Sage M, Lu W, et al. (2001) Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell 105: 683-694.
    • (2001) Cell , vol.105 , pp. 683-694
    • Zheng, B.1    Albrecht, U.2    Kaasik, K.3    Sage, M.4    Lu, W.5
  • 37
    • 0033536228 scopus 로고    scopus 로고
    • The mPer2 gene encodes a functional component of the mammalian circadian clock
    • Zheng B, Larkin DW, Albrecht U, Sun ZS, Sage M, et al. (1999) The mPer2 gene encodes a functional component of the mammalian circadian clock. Nature 400: 169-173.
    • (1999) Nature , vol.400 , pp. 169-173
    • Zheng, B.1    Larkin, D.W.2    Albrecht, U.3    Sun, Z.S.4    Sage, M.5
  • 38
    • 0037126636 scopus 로고    scopus 로고
    • Glucocorticoid hormones inhibit food-induced phase-shifting of peripheral circadian oscillators
    • Le Minh N, Damiola F, Tronche F, Schutz G, Schibler U (2001) Glucocorticoid hormones inhibit food-induced phase-shifting of peripheral circadian oscillators. Embo J 20: 7128-7136.
    • (2001) Embo J , vol.20 , pp. 7128-7136
    • Le Minh, N.1    Damiola, F.2    Tronche, F.3    Schutz, G.4    Schibler, U.5
  • 39
    • 38349078243 scopus 로고    scopus 로고
    • Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet
    • Kudo T, Kawashima M, Tamagawa T, Shibata S (2008) Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet. Am J Physiol Endocrinol Metab 294: E120-130.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Kudo, T.1    Kawashima, M.2    Tamagawa, T.3    Shibata, S.4
  • 41
    • 10344224570 scopus 로고    scopus 로고
    • The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity
    • Zhang J, Huang W, Qatanani M, Evans RM, Moore DD (2004) The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity. J Biol Chem 279: 49517-49522.
    • (2004) J Biol Chem , vol.279 , pp. 49517-49522
    • Zhang, J.1    Huang, W.2    Qatanani, M.3    Evans, R.M.4    Moore, D.D.5
  • 42
  • 43
    • 0027023614 scopus 로고
    • The role of the transcriptional activator protein DBP in circadian liver gene expression
    • Wuarin J, Falvey E, Lavery D, Talbot D, Schmidt E, et al. (1992) The role of the transcriptional activator protein DBP in circadian liver gene expression. J Cell Sci Suppl 16: 123-127.
    • (1992) J Cell Sci , Issue.SUPPL. 16 , pp. 123-127
    • Wuarin, J.1    Falvey, E.2    Lavery, D.3    Talbot, D.4    Schmidt, E.5
  • 44
    • 0034654479 scopus 로고    scopus 로고
    • CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP
    • Ripperger JA, Shearman LP, Reppert SM, Schibler U (2000) CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP. Genes Dev 14: 679-689.
    • (2000) Genes Dev , vol.14 , pp. 679-689
    • Ripperger, J.A.1    Shearman, L.P.2    Reppert, S.M.3    Schibler, U.4
  • 45
    • 33644617485 scopus 로고    scopus 로고
    • Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions
    • Ripperger JA, Schibler U (2006) Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions. Nat Genet 38: 369-374.
    • (2006) Nat Genet , vol.38 , pp. 369-374
    • Ripperger, J.A.1    Schibler, U.2
  • 46
    • 0037790917 scopus 로고    scopus 로고
    • The enzymes, regulation, and genetics of bile acid synthesis
    • Russell DW (2003) The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem 72: 137-174.
    • (2003) Annu Rev Biochem , vol.72 , pp. 137-174
    • Russell, D.W.1
  • 47
    • 1242269851 scopus 로고    scopus 로고
    • Regulation of bile acid synthesis: Pathways, nuclear receptors, and mechanisms
    • Chiang JY (2004) Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms. J Hepatol 40: 539-551.
    • (2004) J Hepatol , vol.40 , pp. 539-551
    • Chiang, J.Y.1
  • 48
    • 0034950514 scopus 로고    scopus 로고
    • The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp
    • Denson LA, Sturm E, Echevarria W, Zimmerman TL, Makishima M, et al. (2001) The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp. Gastroenterology 121: 140-147.
    • (2001) Gastroenterology , vol.121 , pp. 140-147
    • Denson, L.A.1    Sturm, E.2    Echevarria, W.3    Zimmerman, T.L.4    Makishima, M.5
  • 49
    • 0035800772 scopus 로고    scopus 로고
    • Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor
    • Ananthanarayanan M, Balasubramanian N, Makishima M, Mangelsdorf DJ, Suchy FJ (2001) Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. J Biol Chem 276: 28857-28865.
    • (2001) J Biol Chem , vol.276 , pp. 28857-28865
    • Ananthanarayanan, M.1    Balasubramanian, N.2    Makishima, M.3    Mangelsdorf, D.J.4    Suchy, F.J.5
  • 50
    • 0346100571 scopus 로고    scopus 로고
    • Enterohepatic bile salt transporters in normal physiology and liver disease
    • Kullak-Ublick GA, Stieger B, Meier PJ (2004) Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology 126: 322-342.
    • (2004) Gastroenterology , vol.126 , pp. 322-342
    • Kullak-Ublick, G.A.1    Stieger, B.2    Meier, P.J.3
  • 51
    • 0242665373 scopus 로고    scopus 로고
    • Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity
    • Guo GL, Lambert G, Negishi M, Ward JM, Brewer HB Jr, et al. (2003) Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity. J Biol Chem 278: 45062-45071.
    • (2003) J Biol Chem , vol.278 , pp. 45062-45071
    • Guo, G.L.1    Lambert, G.2    Negishi, M.3    Ward, J.M.4    Brewer Jr, H.B.5
  • 52
    • 0028868818 scopus 로고
    • Hormonal regulation of the cholesterol 7 alpha-hydroxylase gene (CYP7)
    • Crestani M, Stroup D, Chiang JY (1995) Hormonal regulation of the cholesterol 7 alpha-hydroxylase gene (CYP7). J Lipid Res 36: 2419-2432.
    • (1995) J Lipid Res , vol.36 , pp. 2419-2432
    • Crestani, M.1    Stroup, D.2    Chiang, J.Y.3
  • 53
    • 29444434655 scopus 로고    scopus 로고
    • The human Na+-taurocholate cotransporting polypeptide gene is activated by glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma coactivator-1alpha, and suppressed by bile acids via a small heterodimer partner-dependent mechanism
    • Eloranta JJ, Jung D, Kullak-Ublick GA (2006) The human Na+-taurocholate cotransporting polypeptide gene is activated by glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma coactivator-1alpha, and suppressed by bile acids via a small heterodimer partner-dependent mechanism. Mol Endocrinol 20: 65-79.
    • (2006) Mol Endocrinol , vol.20 , pp. 65-79
    • Eloranta, J.J.1    Jung, D.2    Kullak-Ublick, G.A.3
  • 54
    • 34447556690 scopus 로고    scopus 로고
    • Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis
    • Noshiro M, Usui E, Kawamoto T, Kubo H, Fujimoto K, et al. (2007) Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis. J Biol Rhythms 22: 299-311.
    • (2007) J Biol Rhythms , vol.22 , pp. 299-311
    • Noshiro, M.1    Usui, E.2    Kawamoto, T.3    Kubo, H.4    Fujimoto, K.5
  • 55
    • 0019984161 scopus 로고
    • Hepatic uptake of bile acids in man. Fasting and postprandial concentrations of individual bile acids in portal venous and systemic blood serum
    • Angelin B, Bjorkhem I, Einarsson K, Ewerth S (1982) Hepatic uptake of bile acids in man. Fasting and postprandial concentrations of individual bile acids in portal venous and systemic blood serum. J Clin Invest 70: 724-731.
    • (1982) J Clin Invest , vol.70 , pp. 724-731
    • Angelin, B.1    Bjorkhem, I.2    Einarsson, K.3    Ewerth, S.4
  • 56
    • 1842479160 scopus 로고    scopus 로고
    • Gene- and tissue-specific alterations of circadian clock gene expression in streptozotocin-induced diabetic mice under restricted feeding
    • Oishi K, Kasamatsu M, Ishida N (2004) Gene- and tissue-specific alterations of circadian clock gene expression in streptozotocin-induced diabetic mice under restricted feeding. Biochem Biophys Res Commun 317: 330-334.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 330-334
    • Oishi, K.1    Kasamatsu, M.2    Ishida, N.3
  • 58
    • 0036118755 scopus 로고    scopus 로고
    • Various S-GOT/S-GPT ratios in nonviral liver disorders and related physical conditions and life-style
    • Mukai M, Ozasa K, Hayashi K, Kawai K (2002) Various S-GOT/S-GPT ratios in nonviral liver disorders and related physical conditions and life-style. Dig Dis Sci 47: 549-555.
    • (2002) Dig Dis Sci , vol.47 , pp. 549-555
    • Mukai, M.1    Ozasa, K.2    Hayashi, K.3    Kawai, K.4
  • 59
    • 0031902086 scopus 로고    scopus 로고
    • Liver transferase activity in healthy Japanese employees aged 18-39 years
    • Nakamura K, Motohashi Y, Kikuchi S, Tanaka M, Nakano S (1998) Liver transferase activity in healthy Japanese employees aged 18-39 years. Ind Health 36: 218-222.
    • (1998) Ind Health , vol.36 , pp. 218-222
    • Nakamura, K.1    Motohashi, Y.2    Kikuchi, S.3    Tanaka, M.4    Nakano, S.5
  • 60
    • 0001364054 scopus 로고
    • Shift work and health
    • Thiis-Evensen E (1958) Shift work and health. Ind Med Surg 27: 493-497.
    • (1958) Ind Med Surg , vol.27 , pp. 493-497
    • Thiis-Evensen, E.1
  • 61
  • 62
    • 33645821043 scopus 로고    scopus 로고
    • Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration
    • Huang W, Ma K, Zhang J, Qatanani M, Cuvillier J, et al. (2006) Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science 312: 233-236.
    • (2006) Science , vol.312 , pp. 233-236
    • Huang, W.1    Ma, K.2    Zhang, J.3    Qatanani, M.4    Cuvillier, J.5


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