Smad6 inhibits the transcriptional activity of Tbx6 by mediating its degradation

Journal of Biological Chemistry

Volumn 284, Issue 35, 2009, Pages 23481-23490

  Chen, Yue Lei ^a   Liu, Bin ^a   Zhou, Zhen Ning ^a   Hu, Rui Ying ^a   Fei, Cong ^a   Xie, Zhi Hui ^a   Ding, Xiaoyan ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; E3 LIGASE; EMBRYONIC DEVELOPMENT; FUNCTIONAL INTERACTION; GENE ACTIVATION; GENE FAMILIES; MOLECULAR MECHANISM; PROTEIN FAMILY; PROTEIN LEVEL; SMALL INTERFERING RNA; TARGET GENES; TISSUE HOMEOSTASIS; TRANSCRIPTIONAL ACTIVITY; UBIQUITIN;

CELL MEMBRANES; DEGRADATION; GENES; NUCLEIC ACIDS; RNA;

PROTEINS;

BONE MORPHOGENETIC PROTEIN; MYOGENIC FACTOR 5; PROTEASOME; SMAD6 PROTEIN; SMALL INTERFERING RNA; SMURF1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBX6; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UBIQUITINATION;

ANIMALS; CELL LINE; DOWN-REGULATION; HUMANS; MICE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SMAD6 PROTEIN; TRANSCRIPTION FACTORS; UBIQUITIN-PROTEIN LIGASES;

EID: 69949164460     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.007864     Document Type: Article

References (43)

1. Hogan, B. L. (1996) Genes Dev. 10, 1580-1594
2. Chen, D., Zhao, M., and Mundy, G. R. (2004) Growth Factors 22, 233-241
3. Massagué, J. (1998) Annu. Rev. Biochem. 67, 753-791
4. Massagué, J., and Chen, Y. G. (2000) Genes Dev. 14, 627-644
5. Massagué, J., and Wotton, D. (2000) EMBO J. 19, 1745-1754
6. Showell, C., Binder, O., and Conlon, F. L. (2004) Dev. Dyn. 229, 201-218
7. Naiche, L. A., Harrelson, Z., Kelly, R. G., and Papaioannou, V. E. (2005) Annu. Rev. Genet. 39, 219-239
8. Packham, E. A., and Brook, J. D. (2003) Hum. Mol. Genet. 12, 37-44
9. Chapman, D. L., Agulnik, I., Hancock, S., Silver, L. M., and Papaioannou, V. E. (1996) Dev. Biol. 180, 534-542
10. Chapman, D. L., and Papaioannou, V. E. (1998) Nature 391, 695-697
11. Hamaguchi, T., Yabe, S., Uchiyama, H., and Murakami, R. (2004) Dev. Biol. 265, 355-368
12. Yamada, M., Revelli, J. P., Eichele, G., Barron, M., and Schwartz, R. J. (2000) Dev. Biol. 228, 95-105
13. Uchiyama, H., Kobayashi, T., Yamashita, A., Ohno, S., and Yabe, S. (2001) Dev. Growth Differ. 43, 657-669
14. Szeto, D. P., and Kimelman, D. (2004) Development 131, 3751-3760
15. Mei, W., Yang, J., Tao, Q., Geng, X., Rupp, R. A., and Ding, X. (2001) FEBS Lett. 505, 47-52
16. Lin, G. F., Geng, X., Chen, Y., Qu, B., Wang, F., Hu, R., and Ding, X. (2003) Dev. Dyn. 226, 51-58
17. He, Z., Li, J., Zhen, C., Feng, L., and Ding, X. (2005) Biochem. Biophys. Res. Commun. 335, 676-683
18. Lou, X., Fang, P., Li, S., Hu, R. Y., Kuerner, K. M., Steinbeisser, H., and Ding, X. (2006) Cell Res. 16, 771-779
19. Messenger, N. J., Kabitschke, C., Andrews, R., Grimmer, D., Núñez Miguel, R., Blundell, T. L., Smith, J. C., and Wardle, F. C. (2005) Dev. Cell 8, 599-610
20. Hanyu, A., Ishidou, Y., Ebisawa, T., Shimanuki, T., Imamura, T., and Miyazono, K. (2001) J. Cell Biol. 155, 1017-1027
21. Chapman, D. L., Cooper-Morgan, A., Harrelson, Z., and Papaioannou, V. E. (2003) Mech. Dev. 120, 837-847
22. Chen, Y., Lin, G. F., Hu, R., Chen, Y., and Ding, X. (2003) Biochem. Biophys. Res. Commun. 310, 121-127
23. Shen, R., Chen, M., Wang, Y. J., Kaneki, H., Xing, L., O'Keefe, R. J., and Chen, D. (2006) J. Biol. Chem. 281, 3569-3576
24. Murakami, G., Watabe, T., Takaoka, K., Miyazono, K., and Imamura, T. (2003) Mol. Biol. Cell 14, 2809-2817
25. White, P. H., and Chapman, D. L. (2005) Genesis 42, 193-202
26. Yasuhiko, Y., Haraguchi, S., Kitajima, S., Takahashi, Y., Kanno, J., and Saga, Y. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 3651-3656
27. Katagiri, T., Yamaguchi, A., Komaki, M., Abe, E., Takahashi, N., Ikeda, T., Rosen, V., Wozney, J. M., Fujisawa-Sehara, A., and Suda, T. (1994) J. Cell Biol. 127, 1755-1766
28. Yamamoto, N., Akiyama, S., Katagiri, T., Namiki, M., Kurokawa, T., and Suda, T. (1997) Biochem. Biophys. Res. Commun. 238, 574-580
29. Salingcarnboriboon, R., Yoshitake, H., Tsuji, K., Obinata, M., Amagasa, T., Nifuji, A., and Noda, M. (2003) Exp. Cell Res. 287, 289-300
30. Ishida, W., Hamamoto, T., Kusanagi, K., Yagi, K., Kawabata, M., Takehara, K., Sampath, T. K., Kato, M., and Miyazono, K. (2000) J. Biol. Chem. 275, 6075-6079
31. Wang, Q., Wei, X., Zhu, T., Zhang, M., Shen, R., Xing, L., O'Keefe, R. J., and Chen, D. (2007) J. Biol. Chem. 282, 10742-10748
32. Shi, Y., Wang, Y. F., Jayaraman, L., Yang, H., Massagué, J., and Pavletich, N. P. (1998) Cell 94, 585-594
33. Bai, S., Shi, X., Yang, X., and Cao, X. (2000) J. Biol. Chem. 275, 8267-8270
34. Bai, S., and Cao, X. (2002) J. Biol. Chem. 277, 4176-4182
35. Datta, P. K., Chytil, A., Gorska, A. E., and Moses, H. L. (1998) J. Biol. Chem. 273, 34671-34674
36. Datta, P. K., and Moses, H. L. (2000) Mol. Cell Biol. 20, 3157-3167
37. Hofmann, M., Schuster-Gossler, K., Watabe-Rudolph, M., Aulehla, A., Herrmann, B. G., and Gossler, A. (2004) Genes Dev. 18, 2712-2717
38. Wittler, L., Shin, E. H., Grote, P., Kispert, A., Beckers, A., Gossler, A., Werber, M., and Herrmann, B. G. (2007) EMBO Rep. 8, 784-789
39. Reshef, R., Maroto, M., and Lassar, A. B. (1998) Genes Dev. 12, 290-303
40. Mayer, R. J. (2000) Nat. Rev. Mol. Cell Biol. 1, 145-148
41. Pickart, C. M. (2001) Annu. Rev. Biochem. 70, 503-533
42. Hiroi, Y., Kudoh, S., Monzen, K., Ikeda, Y., Yazaki, Y., Nagai, R., and Komuro, I. (2001) Nat. Genet. 28, 276-280
43. Garg, V., Kathiriya, I. S., Barnes, R., Schluterman, M. K., King, I. N., Butler, C. A., Rothrock, C. R., Eapen, R. S., Hirayama-Yamada, K., Joo, K., Matsuoka, R., Cohen, J. C., and Srivastava, D. (2003) Nature 424, 443-447