-
1
-
-
84869607824
-
-
www.fda.gov/ohrms/dockets/ac/02/briefing/3909b1.htm.
-
-
-
-
2
-
-
84869607825
-
-
www.fda.gov/ohrms/dockets/ac/02/slides/3909S1- 03-FDA-Tauber/index.htm.
-
-
-
-
3
-
-
4344684430
-
Use of pegylated interferons is associated with an increased incidence of infections during combination treatment of chronic hepatitis C: A side effect of pegylation?
-
Puoti, M. et al. 2004. Use of pegylated interferons is associated with an increased incidence of infections during combination treatment of chronic hepatitis C: a side effect of pegylation? Antivir. Ther. 9: 627-630.
-
(2004)
Antivir. Ther.
, vol.9
, pp. 627-630
-
-
Puoti, M.1
-
4
-
-
0036830507
-
Neutropenia during combination therapy of interferon alfa and ribavirin for chronic hepatitis C
-
Soza, A. et al. 2002. Neutropenia during combination therapy of interferon alfa and ribavirin for chronic hepatitis C. Hepatology 36: 1273-1279.
-
(2002)
Hepatology
, vol.36
, pp. 1273-1279
-
-
Soza, A.1
-
5
-
-
0036830454
-
Side effects of therapy of hepatitis C and their management
-
Fried, M.W. 2002. Side effects of therapy of hepatitis C and their management. Hepatology 36: S237-244.
-
(2002)
Hepatology
, vol.36
-
-
Fried, M.W.1
-
6
-
-
0034068148
-
Severe strongyloidiasis during interferon plus ribavirin therapy for chronic HCV infection
-
Parana, R. et al. 2000. Severe strongyloidiasis during interferon plus ribavirin therapy for chronic HCV infection. Eur. J. Gastroenterol. Hepatol. 12: 245-246.
-
(2000)
Eur. J. Gastroenterol. Hepatol.
, vol.12
, pp. 245-246
-
-
Parana, R.1
-
7
-
-
0142028231
-
Listeria monocytogenes meningitis in a patient with chronic hepatitis C infection, treated by interferon alfa and ribavirin
-
Vander, T. et al. 2003. Listeria monocytogenes meningitis in a patient with chronic hepatitis C infection, treated by interferon alfa and ribavirin. J. Infect. 46: 70-71.
-
(2003)
J. Infect.
, vol.46
, pp. 70-71
-
-
Vander, T.1
-
8
-
-
0035934568
-
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus rib-avirin for initial treatment of chronic hepatitis C: A randomised trial
-
Manns, M.P. et al. 2001. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus rib-avirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 358: 958-965.
-
(2001)
Lancet
, vol.358
, pp. 958-965
-
-
Manns, M.P.1
-
9
-
-
1542378867
-
Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
-
Hadziyannis, S.J. et al. 2004. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann. Intern. Med. 140: 346-355.
-
(2004)
Ann. Intern. Med.
, vol.140
, pp. 346-355
-
-
Hadziyannis, S.J.1
-
10
-
-
22944491444
-
Incidence and severity of infections according to the development of neu-tropenia during combined therapy with pegylated interferon-alpha2a plus ribavirin in chronic hepatitis C infection
-
Juarez-Navarro, A. et al. 2005. Incidence and severity of infections according to the development of neu-tropenia during combined therapy with pegylated interferon-alpha2a plus ribavirin in chronic hepatitis C infection. Methods Find Exp. Clin. Pharmacol. 27: 317-322.
-
(2005)
Methods Find Exp. Clin. Pharmacol.
, vol.27
, pp. 317-322
-
-
Juarez-Navarro, A.1
-
11
-
-
0037517079
-
Side effects of therapy for chronic hepatitis C
-
Russo, M.W. & M.W. Fried. 2003. Side effects of therapy for chronic hepatitis C. Gastroenterology 124: 1711-1719.
-
(2003)
Gastroenterology
, vol.124
, pp. 1711-1719
-
-
Russo, M.W.1
Fried, M.W.2
-
12
-
-
0023706847
-
Recombinant human leukocyte interferon modulates neutrophil function in vitro
-
Gyllenhammar, H. et al. 1988. Recombinant human leukocyte interferon modulates neutrophil function in vitro. J. Interferon Res. 8: 441-449.
-
(1988)
J. Interferon Res.
, vol.8
, pp. 441-449
-
-
Gyllenhammar, H.1
-
13
-
-
0023922303
-
Effects of ribavirin on neu-trophil function
-
Steele R.W. et al. 1988. Effects of ribavirin on neu-trophil function. Am. J. Med. Sci. 295: 503-506.
-
(1988)
Am. J. Med. Sci.
, vol.295
, pp. 503-506
-
-
Steele, R.W.1
-
14
-
-
0025946884
-
Effect of interferon-alpha on neutrophil functions
-
Kasimir, S., J. Brom & W. Konig. 1991. Effect of interferon-alpha on neutrophil functions. Immunology 74: 271-278.
-
(1991)
Immunology
, vol.74
, pp. 271-278
-
-
Kasimir, S.1
Brom, J.2
Konig, W.3
-
15
-
-
0034486375
-
Effects of interferon-alpha on peripheral neutrophil counts and serum granulocyte colony-stimulating factor levels in chronic hepatitis C patients
-
Fukuda, A. et al. 2000. Effects of interferon-alpha on peripheral neutrophil counts and serum granulocyte colony-stimulating factor levels in chronic hepatitis C patients. Cytokines Cell. Mol. Ther. 6: 149-154.
-
(2000)
Cytokines Cell. Mol. Ther.
, vol.6
, pp. 149-154
-
-
Fukuda, A.1
-
16
-
-
0035227284
-
Effect of interferon-alpha on production of reactive oxygen species by human neu-trophils
-
Koie, T. et al. 2001. Effect of interferon-alpha on production of reactive oxygen species by human neu-trophils. Luminescence 16: 39-43.
-
(2001)
Luminescence
, vol.16
, pp. 39-43
-
-
Koie, T.1
-
17
-
-
3242789242
-
IFN-alpha subtypes differentially affect human T cell motility
-
Foster, G.R. et al. 2004. IFN-alpha subtypes differentially affect human T cell motility. J. Immunol. 173: 1663-1670.
-
(2004)
J. Immunol.
, vol.173
, pp. 1663-1670
-
-
Foster, G.R.1
-
18
-
-
18444405565
-
Pharmacokinetics of pegylated in-terferons: What is misleading?
-
Caliceti, P. 2004. Pharmacokinetics of pegylated in-terferons: what is misleading? Dig. Liver Dis. 36(Suppl 3): S334-339.
-
(2004)
Dig. Liver Dis.
, vol.36
, Issue.SUPPL. 3
-
-
Caliceti, P.1
-
19
-
-
0014385564
-
Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of gran-ulocytes by combining centrifugation and sedimentation at 1
-
Boyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of gran-ulocytes by combining centrifugation and sedimentation at 1 g. Scand. J. Clin. Lab. Invest. Suppl. 97: 77-89.
-
(1968)
Scand. J. Clin. Lab. Invest. Suppl.
, vol.97
, pp. 77-89
-
-
Boyum, A.1
-
20
-
-
0036876358
-
Induction of CD69 activation molecule on human neutrophils by GM-CSF, IFN-gamma, and IFN-alpha
-
Atzeni, F. et al. 2002. Induction of CD69 activation molecule on human neutrophils by GM-CSF, IFN-gamma, and IFN-alpha. Cell Immunol. 220: 20-29.
-
(2002)
Cell Immunol.
, vol.220
, pp. 20-29
-
-
Atzeni, F.1
-
21
-
-
0026646454
-
Membrane expression and function of complement receptors CR1 and CR3 on neutrophils from HIV-infected subjects: Modulation by rTNF-alpha and rGM-CSF
-
Capsoni, F. et al. 1992. Membrane expression and function of complement receptors CR1 and CR3 on neutrophils from HIV-infected subjects: modulation by rTNF-alpha and rGM-CSF. Scand. J. Immunol. 36: 541-546.
-
(1992)
Scand. J. Immunol.
, vol.36
, pp. 541-546
-
-
Capsoni, F.1
-
22
-
-
0036307087
-
Rapid suppression of hematopoiesis by standard or pegylated interferon-alpha
-
Peck-Radosavljevic, M. et al. 2002. Rapid suppression of hematopoiesis by standard or pegylated interferon-alpha. Gastroenterology 123: 141-151.
-
(2002)
Gastroenterology
, vol.123
, pp. 141-151
-
-
Peck-Radosavljevic, M.1
-
23
-
-
0029978838
-
A comparative trial of recom-binant interferon alpha 2A versus alpha 2 beta on myelosuppression in healthy adult volunteers
-
Wong, S. et al. 1996. A comparative trial of recom-binant interferon alpha 2A versus alpha 2 beta on myelosuppression in healthy adult volunteers. Hep-atogastroenterology 43: 301-305.
-
(1996)
Hep-atogastroenterology
, vol.43
, pp. 301-305
-
-
Wong, S.1
-
24
-
-
0037179698
-
Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
-
Fried, M.W. et al. 2002. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N. Engl. J. Med. 347: 975-982.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 975-982
-
-
Fried, M.W.1
-
25
-
-
44949222077
-
Prospective assessment of the incidence of infections during pegylated inter-feron (PEG-IFN) plus ribavirin (RBV) treatment for chronic hepatitis C (CHC)
-
Zuin, M. et al. 2004. Prospective assessment of the incidence of infections during pegylated inter-feron (PEG-IFN) plus ribavirin (RBV) treatment for chronic hepatitis C (CHC). Hepatology 40: 329A.
-
(2004)
Hepatology
, vol.40
-
-
Zuin, M.1
-
26
-
-
0031156122
-
Effect of alpha-interferons on immune function
-
Herberman, R.B. 1997. Effect of alpha-interferons on immune function. Semin Oncol. 24: S9-78-S9-80.
-
(1997)
Semin Oncol.
, vol.24
-
-
Herberman, R.B.1
-
27
-
-
0033580768
-
Reducing the immunogenicity and improving the in vivo activity of trichosanthin by site-directed pegylation
-
He, X.H., P.C. Shaw & S.C. Tam. 1999. Reducing the immunogenicity and improving the in vivo activity of trichosanthin by site-directed pegylation. Life Sci. 65: 355-368.
-
(1999)
Life Sci.
, vol.65
, pp. 355-368
-
-
He, X.H.1
Shaw, P.C.2
Tam, S.C.3
-
28
-
-
0028169264
-
Interferon-alpha enhances neutrophil respiratory burst responses to stimulation with influenza A virus and FMLP
-
Little, R., M.R. White & K.L. Hartshorn. 1994. Interferon-alpha enhances neutrophil respiratory burst responses to stimulation with influenza A virus and FMLP. J. I n f e c t . D i s . 170: 802-810.
-
(1994)
J. Infect. Dis .
, vol.170
, pp. 802-810
-
-
Little, R.1
White, M.R.2
Hartshorn, K.L.3
-
29
-
-
0035839192
-
Microscopic localization of PEG-liposomes in a rat model of focal infection
-
Laverman, P. et al. 2001. Microscopic localization of PEG-liposomes in a rat model of focal infection. J. Control Release 75: 347-355.
-
(2001)
J. Control Release
, vol.75
, pp. 347-355
-
-
Laverman, P.1
-
30
-
-
0033844251
-
A dose-ranging study of pegylated interferon alfa-2b and ribavirin in chronic hepatitis C
-
The Hepatitis C Intervention Therapy Group
-
Glue, P. et al. 2000. A dose-ranging study of pegylated interferon alfa-2b and ribavirin in chronic hepatitis C. The Hepatitis C Intervention Therapy Group. Hepatology 32: 647-653.
-
(2000)
Hepatology
, vol.32
, pp. 647-653
-
-
Glue, P.1
-
31
-
-
0023105108
-
Compartmentalization of a haematopoietic growth factor (GM-CSF) by gly-cosaminoglycans in the bone marrow microenviron-ment
-
Gordon, M.Y. et al. 1987. Compartmentalization of a haematopoietic growth factor (GM-CSF) by gly-cosaminoglycans in the bone marrow microenviron-ment. Nature 326: 403-405.
-
(1987)
Nature
, vol.326
, pp. 403-405
-
-
Gordon, M.Y.1
-
32
-
-
0023928595
-
Heparan sulphate bound growth factors: A mechanism for stromal cell mediated haemopoiesis
-
Roberts, R. et al. 1988. Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis. Nature 332: 376-378.
-
(1988)
Nature
, vol.332
, pp. 376-378
-
-
Roberts, R.1
-
33
-
-
1842685045
-
The molecular basis of HCV-mediated immune dysregulation
-
Eisen-Vandervelde, A.L., Z.Q. Yao & Y.S. Hahn. 2004. The molecular basis of HCV-mediated immune dysregulation. Clin. Immunol. 111: 16-21.
-
(2004)
Clin. Immunol.
, vol.111
, pp. 16-21
-
-
Eisen-Vandervelde, A.L.1
Yao, Z.Q.2
Hahn, Y.S.3
-
34
-
-
0033869507
-
Detachment of human immunodeficiency virus type 1 from germinal centers by blocking complement receptor type 2
-
Kacani, L. et al. 2000. Detachment of human immunodeficiency virus type 1 from germinal centers by blocking complement receptor type 2. J. V i r o l . 74: 7997-8002.
-
(2000)
J. Virol .
, vol.74
, pp. 7997-8002
-
-
Kacani, L.1
-
36
-
-
0037771321
-
Inhibition of neutrophil apop-tosis by type 1 IFN depends on cross-talk between phosphoinositol 3-kinase, protein kinase C-delta, and NF-kappa B signaling pathways
-
Wang, K. et al. 2003. Inhibition of neutrophil apop-tosis by type 1 IFN depends on cross-talk between phosphoinositol 3-kinase, protein kinase C-delta, and NF-kappa B signaling pathways. J. Immunol. 171(2): 1035-1041.
-
(2003)
J. Immunol.
, vol.171
, Issue.2
, pp. 1035-1041
-
-
Wang, K.1
|