Autoantigens identified by screening a human heart cDNA library with acute rheumatic fever sera

Annals of the New York Academy of Sciences

Volumn 1173, Issue , 2009, Pages 83-91

  Towers, Rebecca J ^a,b,d   Bolm, Maike ^c   Currie, Bart J ^a,b   Chhatwal, Gursharan S ^c   Fagan, Peter K ^a,b  

^a MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^b CHARLES DARWIN UNIVERSITY   (Australia)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^d NONE   (Australia)

Author keywords

Acute rheumatic fever; Australian indigenous communities; Autoantigen; Group A streptococcus; Human heart cDNA expression library

Indexed keywords

ALPHA CATENIN; ALPHAE CATENIN; AUTOANTIBODY; AUTOANTIGEN; BIOLOGICAL MARKER; CATENIN; HEART ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN HEAVY CHAIN; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN 6; NEXILIN; PROTEIN; PROTEIN NUANCE; STRUCTURAL MAINTENANCE OF CHROMOSOME PROTEIN 2; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR INTERACTING PROTEIN; ZINC FINGER PROTEIN;

ADULT; ANTIGEN DETECTION; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BLOOD ANALYSIS; CONFERENCE PAPER; CONTROLLED STUDY; DNA LIBRARY; ENZYME LINKED IMMUNOSORBENT ASSAY; GROUP A STREPTOCOCCAL INFECTION; HEART VALVE SURGERY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PATHOGENESIS; RHEUMATIC FEVER; RHEUMATIC HEART DISEASE; SCREENING; SERODIAGNOSIS; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY;

STREPTOCOCCUS SP. 'GROUP A';

EID: 69949140740     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.04653.x     Document Type: Conference Paper

References (36)

1. Carapetis, J.R., A.C. Steer, E.K. Mulholland & M. Weber. 2005. The global burden of group A strepto-coccal diseases. Lancet Infect. Dis. 5: 685-694.
2. Carapetis, J.R., D.R. Wolff & B.J. Currie. 1996. Acute rheumatic fever and rheumatic heart disease in the top end of Australia's Northern Territory. Med. J. Aust. 164: 146-149.
3. Carapetis, J.R. & B.J. Currie. 1997. Clinical epidemiology of rheumatic fever and rheumatic heart disease in tropical Australia. Adv. Exp. Med. Biol. 418: 233-236.
4. McDonald, M., B.J. Currie & J.R. Carapetis. 2004. Acute rheumatic fever: a chink in the chain that links the heart to the throat? Lancet Infect. Dis. 4: 240-245.
5. Field, B. 2004. Rheumatic heart disease: all but forgotten in Australia except among Aboriginal and Torres Strait Islander peoples. Report from the Australian Institute of Health and Welfare, Canberra.
6. Special Writing Group of the Committee on Rheumatic Fever, E., and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association. 1992. Guidelines for the diagnosis of rheumatic fever. Jones Criteria, 1992 update. JAMA 268: 2069-2073.
7. Essop, M.R. & T. Omar. 2004. Rheumatic fever. In Cardiology. M.H. Crawford, J.P. DiMarco & W.J. Paulua, Eds.: 1061-1069. Mosby Press. Edinburgh.
8. Ralph, A., S. Jacups, K. McGough, et al. 2006. The challenge of acute rheumatic fever diagnosis in a high-incidence population: a prospective study and proposed guidelines for diagnosis in Australia's Northern Territory. Heart Lung Circ. 15: 113-118.
9. Pereira, B.A., N.A. da Silva, L.E. Andrade, et al. 2007. Jones criteria and underdiagnosis of rheumatic fever. Indian J. Pediatr. 74: 117-121.
10. Borges, F., M.L. Barbosa, R.B. Borges, et al. 2005. Clinical and demographic characteristics of 99 episodes of rheumatic fever in Acre, the Brazilian Amazon. Arq. Bras. Cardiol. 84: 111-114.
11. Bessen, D.E., L.G. Veasy, H.R. Hill, et al. 1995. Sero-logical evidence for a Class I group A streptococcal infection among rheumatic fever patients. J. I n f e c t . Dis. 172: 1608-1611.
12. Norton, R.E., M. Heuzenroeder & P.A. Manning. 1996. Antigenic epitope mapping of the M24 protein of Streptococcus pyogenes: implications for serodiagnosis of rheumatic fever. FEMS Immunol. Med. Microbiol. 16: 267-271.
13. Brandt, E.R., P.J. Yarwood, D.J. McMillan, et al. 2001. Antibody levels to the class I and II epitopes of the M protein and myosin are related to group A streptococcal exposure in endemic populations. Int. Immunol. 13: 1335-1343.
14. Galvin, J.E., M.E. Hemric, K. Ward & M.W. Cunningham. 2000. Cytotoxic mAb from rheumatic carditis recognizes heart valves and laminin. J. Clin. Invest. 106: 217-224.
15. Jones, K.F., S.S. Whitehead, M.W. Cunningham & V.A. Fischetti. 2000. Reactivity of rheumatic fever and scarlet fever patients' sera with group A strep-tococcal M protein, cardiac myosin, and cardiac tropomyosin: a retrospective study. Infect. Immun. 68: 7132-7136.
16. Eichbaum, Q.G., D.W. Beatty & M.I. Parker. 1994. Identification of cardiac autoantigens in human heart cDNA libraries using acute rheumatic fever sera. J. Autoimmun. 7: 243-261.
17. Tontsch, D., S. Pankuweit & B. Maisch. 2000. Au-toantibodies in the sera of patients with rheumatic heart disease: characterisation of myocardial antigens by two dimensional immunoblotting and N-terminal sequence analysis. Clin. Exp. Immunol. 121: 270-274.
18. Szczesna-Cordary, D., G. Guzman, S.S. Ng & J. Zho. 2004. Familial hypertrophic cardiomyopathy-linked alterations in Ca2+ binding of human cardiac myosin regulatory light chain affect cardiac muscle contraction. J. Biol. Chem. 270: 3535-3542.
19. Ravkilde, J., H.E. Bøtker, P. Søgaard, et al. 1994. Human ventricular myosin light chain isotype 1 as a marker of myocardial injury. Cardiology 84: 135-144.
20. Carlton-Conway, D., R. Tulloh, L. Wood & D. Kan-abar. 2004. Vitamin D deficiency and cardiac failure in infancy. J. R. Soc. Med. 97: 238-239.
21. Adorini, L. 2002. Immunomodulatory effects of vitamin D receptor ligands in autoimmune diseases. Int. Immunol. 2: 1017-1028.
22. Bahr, G.M., L.J. Eales, K.E. Nye, et al. 1989. An association between Gc (vitamin D-binding proteins) alleles and susceptibility to rheumatic fever. Immunol. 67: 126-128.
23. Khachigian, L.M. 2006. Early growth response-1 in cardiovascular pathobiology. Circ. Res. 98: 186-191.
24. Gitler, A.D., M.M. Lu, Y.Q. Jiang, et al. 2003. Molecular markers of cardiac endocardial cushion development. Dev. Dyn. 228: 643-650.
25. Mutsabara, S. & M. Ozawa. 2001. Expression of alpha-catenin in alpha-catenin-deficient cells increases resistance to sphingosine-induced apoptosis. J. Cell Biol. 154: 573-584.
26. Lee, Y.S. & Y.Y. Chou. 1998. Electron microscopic observations of apoptotic cells in various cardiovascular diseases. Chin. Med. J. (Engl.) 111: 428-432.
27. Wang, W., W. Zhang, Y. Han, et al. 2005. NELIN, a new F-actin associated protein, stimulates HeLa cell migration and adhesion. Biochem. Biophys. Res. Com-mun. 330: 1127-1131.
28. Elisei, R., D. Weightman, P. Kendall-Taylor, et al. 1993. Muscle autoantigens in thyroid associated opthalmopathy: the limits of molecular genetics. J. Endochrinol. Invest. 16: 533-540.
29. Lee, S.Y., Y. Obata, M. Yoshida, et al. 2003. Immu-nomic analysis of human sarcoma. Proc. Natl. Acad. Sci. USA 100: 2651-2656.
30. Zhen, Y.-Y., T. Libotte, M. Munck, et al. 2002. NUANCE, a giant protein connecting the nucleus and actin cytoskeleton. J. Cell Sci. 115: 3207-3222.
31. Mathur, P., S. Kaga, L. Zhan, et al. 2005. Potential candidates for ischemic preconditioning-associated vascular growth pathways revealed by antibody array. Am. J. Physiol. Heart Circ. Physiol. 288: H3006-3010.
32. Sesso, R.C., O.L. Ramos & A.B. Pereira. 1986. Detection of IgG-rheumatoid factor in sera of patients with acute poststreptococcal glomerulonephritis and its relationship with circulating immune complexes. Clin. Neph. 26: 55-60.
33. Guilherme, L., J. Kalil & M. Cunningham. 2006. Molecular mimicry in the autioimmune pathogenesis of rheumatic heart disease. Autoimmunity 39: 31-39. (Pubitemid 43878518)
34. Knip, M. & H. Siljander. 2008. Autoimmune mechanisms in type 1 diabetes. Autoimmun. Rev. 7: 550-557.
35. Koenig, M., M. Dieudé & J.L. Senécal. 2008. Predictive value of antinuclear autoantibodies: the lessons of the systemic sclerosis autoantibodies. Autoimmun. Rev. 7: 588-593
36. Bizzaro, N. 2007. Autoantibodies as predictors of disease: the clinical and experimental evidence. Autoimmune. Rev. 6: 325-333.