-
1
-
-
0028237683
-
Definition of a core region of RAG-2 that is functional in V(D)J recombination
-
Sadofsky MJ, Hesse JE, Gellert M. Definition of a core region of RAG-2 that is functional in V(D)J recombination. Nucleic Acids Res 1994 22 : 1805 1809.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 1805-1809
-
-
Sadofsky, M.J.1
Hesse, J.E.2
Gellert, M.3
-
3
-
-
0027197151
-
Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination
-
Silver DP, Spanopoulou E, Mulligan RC, Baltimore D. Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination. Proc Natl Acad Sci USA 1993 90 : 6100 6104.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6100-6104
-
-
Silver, D.P.1
Spanopoulou, E.2
Mulligan, R.C.3
Baltimore, D.4
-
4
-
-
0030811531
-
A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity
-
McMahan CJ, Difilippantonio MJ, Rao N, Spanopoulou E, Schatz DG. A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity. Mol Cell Biol 1997 17 : 4544 4552.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4544-4552
-
-
McMahan, C.J.1
Difilippantonio, M.J.2
Rao, N.3
Spanopoulou, E.4
Schatz, D.G.5
-
5
-
-
0030871602
-
Complementation of V(D)J recombination deficiency in RAG-1(---) B cells reveals a requirement for novel elements in the N-terminus of RAG-1
-
Roman CA, Cherry SR, Baltimore D. Complementation of V(D)J recombination deficiency in RAG-1(---) B cells reveals a requirement for novel elements in the N-terminus of RAG-1. Immunity 1997 7 : 13 24.
-
(1997)
Immunity
, vol.7
, pp. 13-24
-
-
Roman, C.A.1
Cherry, S.R.2
Baltimore, D.3
-
6
-
-
40049107888
-
Biochemical and folding defects in a RAG1 variant associated with Omenn syndrome
-
Simkus C, Anand P, Bhattacharyya A, Jones JM. Biochemical and folding defects in a RAG1 variant associated with Omenn syndrome. J Immunol 2007 179 : 8332 8340.
-
(2007)
J Immunol
, vol.179
, pp. 8332-8340
-
-
Simkus, C.1
Anand, P.2
Bhattacharyya, A.3
Jones, J.M.4
-
7
-
-
43249105936
-
An immunodeficiency disease with RAG mutations and granulomas
-
Schuetz C, Huck K, Gudowius S et al. An immunodeficiency disease with RAG mutations and granulomas. N Engl J Med 2008 358 : 2030 2038.
-
(2008)
N Engl J Med
, vol.358
, pp. 2030-2038
-
-
Schuetz, C.1
Huck, K.2
Gudowius, S.3
-
8
-
-
0035161258
-
V(D)J recombination defects in lymphocytes due to RAG mutations: Severe immunodeficiency with a spectrum of clinical presentations
-
Villa A, Sobacchi C, Notarangelo LD et al. V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations. Blood 2001 97 : 81 8.
-
(2001)
Blood
, vol.97
, pp. 81-8
-
-
Villa, A.1
Sobacchi, C.2
Notarangelo, L.D.3
-
9
-
-
0018992813
-
ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation
-
Ciechanover A, Heller H, Elias S, Haas AL, Hershko A. ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation. Proc Natl Acad Sci USA 1980 77 : 1365 1368.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 1365-1368
-
-
Ciechanover, A.1
Heller, H.2
Elias, S.3
Haas, A.L.4
Hershko, A.5
-
10
-
-
0019000271
-
Proposed role of ATP in protein breakdown: Conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis
-
Hershko A, Ciechanover A, Heller H, Haas AL, Rose IA. Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis. Proc Natl Acad Sci USA 1980 77 : 1783 1786.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 1783-1786
-
-
Hershko, A.1
Ciechanover, A.2
Heller, H.3
Haas, A.L.4
Rose, I.A.5
-
11
-
-
0842303313
-
Back to the future with ubiquitin
-
Pickart CM. Back to the future with ubiquitin. Cell 2004 116 : 181 190.
-
(2004)
Cell
, vol.116
, pp. 181-190
-
-
Pickart, C.M.1
-
12
-
-
0021099710
-
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown
-
Hershko A, Heller H, Elias S, Ciechanover A. Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown. J Biol Chem 1983 258 : 8206 8214.
-
(1983)
J Biol Chem
, vol.258
, pp. 8206-8214
-
-
Hershko, A.1
Heller, H.2
Elias, S.3
Ciechanover, A.4
-
13
-
-
0034604341
-
Regulation of transcription by ubiquitination without proteolysis: Cdc34-SCF(Met30)-mediated inactivation of the transcription factor Met4
-
Kaiser P, Flick K, Wittenberg C, Reed SI. Regulation of transcription by ubiquitination without proteolysis: Cdc34-SCF(Met30)-mediated inactivation of the transcription factor Met4. Cell 2000 102 : 303 314.
-
(2000)
Cell
, vol.102
, pp. 303-314
-
-
Kaiser, P.1
Flick, K.2
Wittenberg, C.3
Reed, S.I.4
-
14
-
-
0034616943
-
Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain
-
Spence J, Gali RR, Dittmar G, Sherman F, Karin M, Finley D. Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain. Cell 2000 102 : 67 76.
-
(2000)
Cell
, vol.102
, pp. 67-76
-
-
Spence, J.1
Gali, R.R.2
Dittmar, G.3
Sherman, F.4
Karin, M.5
Finley, D.6
-
15
-
-
0028847989
-
A ubiquitin mutant with specific defects in DNA repair and multiubiquitination
-
Spence J, Sadis S, Haas AL, Finley D. A ubiquitin mutant with specific defects in DNA repair and multiubiquitination. Mol Cell Biol 1995 15 : 1265 1273.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1265-1273
-
-
Spence, J.1
Sadis, S.2
Haas, A.L.3
Finley, D.4
-
16
-
-
0032488846
-
The proteasome: Paradigm of a self-compartmentalizing protease
-
Baumeister W, Walz J, Zuhl F, Seemuller E. The proteasome: paradigm of a self-compartmentalizing protease. Cell 1998 92 : 367 380.
-
(1998)
Cell
, vol.92
, pp. 367-380
-
-
Baumeister, W.1
Walz, J.2
Zuhl, F.3
Seemuller, E.4
-
17
-
-
20444403003
-
Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle
-
Jiang H, Chang FC, Ross AE, Lee J, Nakayama K, Nakayama K, Desiderio S. Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle. Mol Cell 2005 18 : 699 709.
-
(2005)
Mol Cell
, vol.18
, pp. 699-709
-
-
Jiang, H.1
Chang, F.C.2
Ross, A.E.3
Lee, J.4
Nakayama, K.5
Nakayama, K.6
Desiderio, S.7
-
18
-
-
0033553532
-
Substrate targeting in the ubiquitin system
-
Laney JD, Hochstrasser M. Substrate targeting in the ubiquitin system. Cell 1999 97 : 427 430.
-
(1999)
Cell
, vol.97
, pp. 427-430
-
-
Laney, J.D.1
Hochstrasser, M.2
-
19
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
-
Huibregtse JM, Scheffner M, Beaudenon S, Howley PM. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci USA 1995 92 : 5249.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5249
-
-
Huibregtse, J.M.1
Scheffner, M.2
Beaudenon, S.3
Howley, P.M.4
-
20
-
-
0033613222
-
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
-
Lorick KL, Jensen JP, Fang S, Ong AM, Hatakeyama S, Weissman AM. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. Proc Natl Acad Sci USA 1999 96 : 11364 11369.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11364-11369
-
-
Lorick, K.L.1
Jensen, J.P.2
Fang, S.3
Ong, A.M.4
Hatakeyama, S.5
Weissman, A.M.6
-
21
-
-
28944435024
-
Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34
-
Petroski MD, Deshaies RJ. Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34. Cell 2005 123 : 1107 1120.
-
(2005)
Cell
, vol.123
, pp. 1107-1120
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
22
-
-
0347994908
-
Autoubiquitylation of the V(D)J recombinase protein RAG1
-
Jones JM, Gellert M. Autoubiquitylation of the V(D)J recombinase protein RAG1. Proc Natl Acad Sci USA 2003 100 : 15446 15451.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15446-15451
-
-
Jones, J.M.1
Gellert, M.2
-
23
-
-
0037335702
-
The RAG1 N-terminal domain is an E3 ubiquitin ligase
-
Yurchenko V, Xue Z, Sadofsky M. The RAG1 N-terminal domain is an E3 ubiquitin ligase. Genes Dev 2003 17 : 581 585.
-
(2003)
Genes Dev
, vol.17
, pp. 581-585
-
-
Yurchenko, V.1
Xue, Z.2
Sadofsky, M.3
-
24
-
-
0030959658
-
Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster
-
Bellon SF, Rodgers KK, Schatz DG, Coleman JE, Steitz TA. Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster. Nat Struct Biol 1997 4 : 586 591.
-
(1997)
Nat Struct Biol
, vol.4
, pp. 586-591
-
-
Bellon, S.F.1
Rodgers, K.K.2
Schatz, D.G.3
Coleman, J.E.4
Steitz, T.A.5
-
25
-
-
0030570467
-
A zinc-binding domain involved in the dimerization of RAG1
-
Rodgers KK, Bu Z, Fleming KG, Schatz DG, Engelman DM, Coleman JE. A zinc-binding domain involved in the dimerization of RAG1. J Mol Biol 1996 260 : 70 84.
-
(1996)
J Mol Biol
, vol.260
, pp. 70-84
-
-
Rodgers, K.K.1
Bu, Z.2
Fleming, K.G.3
Schatz, D.G.4
Engelman, D.M.5
Coleman, J.E.6
-
26
-
-
0034682718
-
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases
-
Zheng N, Wang P, Jeffrey PD, Pavletich NP. Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell 2000 102 : 533 539.
-
(2000)
Cell
, vol.102
, pp. 533-539
-
-
Zheng, N.1
Wang, P.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
27
-
-
0030026070
-
Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry
-
Wilm M, Shevchenko A, Houthaeve T, Breit S, Schweigerer L, Fotsis T, Mann M. Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry. Nature 1996 379 : 466 469.
-
(1996)
Nature
, vol.379
, pp. 466-469
-
-
Wilm, M.1
Shevchenko, A.2
Houthaeve, T.3
Breit, S.4
Schweigerer, L.5
Fotsis, T.6
Mann, M.7
-
28
-
-
62749159936
-
Karyopherin alpha 1 is a putative substrate of the RAG1 ubiquitin ligase
-
doi:.
-
Simkus C, Mayika M, Jones JM. Karyopherin alpha 1 is a putative substrate of the RAG1 ubiquitin ligase. Mol Immunol 2009 46 : 1319 1325. doi :.
-
(2009)
Mol Immunol
, vol.46
, pp. 1319-1325
-
-
Simkus, C.1
Mayika, M.2
Jones, J.M.3
-
29
-
-
0023659483
-
Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals
-
Hesse JE, Lieber MR, Gellert M, Mizuuchi K. Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals. Cell 1987 49 : 775 783.
-
(1987)
Cell
, vol.49
, pp. 775-783
-
-
Hesse, J.E.1
Lieber, M.R.2
Gellert, M.3
Mizuuchi, K.4
-
30
-
-
21244493533
-
The unique region of surrogate light chain component lambda5 is a heavy chain-specific regulator of precursor B cell receptor signaling
-
Guloglu FB, Bajor E, Smith BP, Roman CA. The unique region of surrogate light chain component lambda5 is a heavy chain-specific regulator of precursor B cell receptor signaling. J Immunol 2005 175 : 358 366.
-
(2005)
J Immunol
, vol.175
, pp. 358-366
-
-
Guloglu, F.B.1
Bajor, E.2
Smith, B.P.3
Roman, C.A.4
-
31
-
-
0001679473
-
ALIGN: A program to superimpose protein coordinates
-
Cohen GE. ALIGN: a program to superimpose protein coordinates. J Appl Crystallogr 1997 30 : 1160 1161.
-
(1997)
J Appl Crystallogr
, vol.30
, pp. 1160-1161
-
-
Cohen, G.E.1
-
32
-
-
33947243954
-
A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate
-
Li W, Tu D, Brunger AT, Ye Y. A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate. Nature 2007 446 : 333 337.
-
(2007)
Nature
, vol.446
, pp. 333-337
-
-
Li, W.1
Tu, D.2
Brunger, A.T.3
Ye, Y.4
-
33
-
-
27144495057
-
E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer
-
Eletr ZM, Huang DT, Duda DM, Schulman BA, Kuhlman B. E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer. Nat Struct Mol Biol 2005 12 : 933 934.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 933-934
-
-
Eletr, Z.M.1
Huang, D.T.2
Duda, D.M.3
Schulman, B.A.4
Kuhlman, B.5
-
34
-
-
35148869981
-
Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains
-
Gazdoiu S, Yamoah K, Wu K, Pan ZQ. Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains. Mol Cell Biol 2007 27 : 7041 7052.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7041-7052
-
-
Gazdoiu, S.1
Yamoah, K.2
Wu, K.3
Pan, Z.Q.4
-
36
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart CM. Mechanisms underlying ubiquitination. Annu Rev Biochem 2001 70 : 503 533.
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
37
-
-
0034791090
-
Ubiquitin enters the new millennium
-
Pickart CM. Ubiquitin enters the new millennium. Mol Cell 2001 8 : 499 504.
-
(2001)
Mol Cell
, vol.8
, pp. 499-504
-
-
Pickart, C.M.1
-
38
-
-
0037610801
-
Binding and recognition in the assembly of an active BRCA1-BARD1 ubiquitin-ligase complex
-
Brzovic PS, Keeffe JR, Nishikawa H, Miyamoto K, Fox D 3rd., Fukuda M, Ohta T, Klevit R. Binding and recognition in the assembly of an active BRCA1-BARD1 ubiquitin-ligase complex. Proc Natl Acad Sci USA 2003 100 : 5646 5651.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5646-5651
-
-
Brzovic, P.S.1
Keeffe, J.R.2
Nishikawa, H.3
Miyamoto, K.4
Fox III, D.5
Fukuda, M.6
Ohta, T.7
Klevit, R.8
|