BMD, clinical risk factors and their combination for hip fracture prevention

Osteoporosis International

Volumn 20, Issue 10, 2009, Pages 1675-1682

  Johansson, H ^a   Kanis, J A ^a   Oden, A ^a   Johnell, O ^b   McCloskey, E ^a,c  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c NORTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

FRAX ; Hip fracture; Number needed to treat; Positive predictive value

Indexed keywords

AGE; AGED; ARTICLE; BONE DENSITOMETRY; BONE DENSITY; CONTROLLED STUDY; FEMALE; FEMUR NECK; HIGH RISK POPULATION; HIP; HIP FRACTURE; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROBABILITY; RISK ASSESSMENT; RISK FACTOR; SENSITIVITY ANALYSIS; UNITED KINGDOM;

AGE FACTORS; AGED; BONE DENSITY; EPIDEMIOLOGIC METHODS; FEMALE; FEMUR NECK; HIP FRACTURES; HUMANS; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; OSTEOPOROTIC FRACTURES;

EID: 69949131336     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-009-0845-x     Document Type: Article

References (50)

1. D Marshall O Johnell H Wedel 1996 Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures Br Med J 312 1254 1259
2. O Johnell JA Kanis A Oden H Johansson C De Laet P Delmas JA Eisman, et al. 2005 Predictive value of bone mineral density for hip and other fractures J Bone Miner Res 20 1185 1194 (Pubitemid 40863806)
3. JA Kanis O Johnell A Oden B Jönsson C De Laet A Dawson 2000 Risk of hip fracture according to World Health Organization criteria for osteopenia and osteoporosis Bone 27 585 590
4. SL Hui CW Slemenda CC Johnston 1988 Age and bone mass as predictors of fracture in a prospective study J Clin Invest 81 1804 1809
5. CEDH De Laet BA van Hout H Burger A Hofman HAP Pols 1997 Bone density and risk of hip fracture in men and women: cross sectional analysis Br Med J 315 221 225
6. World Health Organization (1994) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. WHO Technical Report Series 843. WHO, Geneva
7. C De Laet A Oden H Johansson O Johnell B Jonsson JA Kanis 2005 The impact of the use of multiple risk indicators for fracture on case-finding strategies: a mathematical approach Osteoporos Int 16 313 318
8. ES Siris PD Miller E Barrett-Connor KG Faulkner LE Wehren TA Abbott, et al. 2001 Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: results from the National Osteoporosis Risk Assessment JAMA 286 2815 2822
9. JA Kanis O Johnell A Oden B Jönsson A Dawson W Dere 2000 Risk of hip fracture derived from relative risks: an analysis applied to the population of Sweden Osteoporos Int 11 120 127
10. JA Kanis O Johnell A Oden C De Laet B Jonsson A Dawson 2002 Ten-year risk of osteoporotic fracture and the effect of risk factors on screening strategies Bone 30 251 285
11. JA Kanis H Johansson A Oden O Johnell C De Laet JA Eisman, et al. 2004 A family history of fracture and fracture risk: a meta-analysis Bone 35 1029 1037 (Pubitemid 39487348)
12. JA Kanis H Johansson A Oden O Johnell C De Laet LJ Melton III, et al. 2004 A meta-analysis of prior corticosteroid use and fracture risk J Bone Miner Res 19 893 899 (Pubitemid 41103445)
13. JA Kanis O Johnell C De Laet, et al. 2004 A meta-analysis of previous fracture and subsequent fracture risk Bone 35 375 382 (Pubitemid 38953182)
14. JA Kanis H Johansson O Johnell A Oden C De Laet JA Eisman, et al. 2005 Alcohol intake as a risk factor for fracture Osteoporos Int 16 737 742
15. JA Kanis H Johansson A Oden, et al. 2005 A meta-analysis of milk intake and fracture risk: low utility for case finding Osteoporos Int 16 799 804
16. JA Kanis O Johnell A Oden H Johansson C De Laet JA Eisman, et al. 2005 Smoking and fracture risk: a meta-analysis Osteoporos Int 16 155 162
17. C De Laet JA Kanis A Oden H Johansson O Johnell P Delmas, et al. 2005 Body mass index as a prediction of fracture risk. A meta-analysis Osteoporos Int 16 1330 1338
18. JA Kanis A Oden O Johnell, et al. 2007 The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women Osteoporos Int 18 1033 1046
19. JA Kanis O Johnell A Oden E [tmp] McCloskey 2008 FRAX™ and the assessment of fracture probability in men and women from the UK Osteoporos Int 19 385 397
20. Kanis JA on behalf of the World Health Organization Scientific Group (2008) Assessment of osteoporosis at the primary health-care level. Technical Report. WHO Collaborating Centre, University of Sheffield, UK, 2008
21. JA Kanis O Johnell 2005 Requirements for DXA for the management of osteoporosis in Europe Osteoporos Int 16 229 238
22. JA Kanis P Delmas P Burckhardt C Cooper D Torgerson European Foundation for Osteoporosis and Bone Disease 1997 Guidelines for diagnosis and management of osteoporosis Osteoporos Int 7 390 406
23. Royal College of Physicians (1999) Osteoporosis: clinical guidelines for prevention and treatment. The Royal College of Physicians of London
24. Royal College of Physicians (2001) Osteoporosis: clinical guidelines for prevention and treatment. Update on pharmacological interventions and an algorithm for management. RCP, London
25. A Hofman DE Grobbee PT de Jong FA van den Ouweland 1991 Determinants of disease and disability in the elderly: the Rotterdam Elderly Study Eur J Epidemiol 7 403 422
26. CEDH De Laet BA Van Hout H Burger A Hofman AEAM Weel HAP Pols 1998 Hip fracture prediction in elderly men and women: validation of the Rotterdam study J Bone Miner Res 13 1587 1593
27. TW O'Neill D Felsenberg J Barlow C Cooper JA Kanis AJ Silman 1996 The prevalence of vertebral deformity in European men and women: the European Vertebral Osteoporosis Study J Bone Miner Res 11 1010 1017
28. N Kreiger A Tenenhouse L Joseph, et al. 1999 The Canadian Multicentre Osteoporosis Study CaMos: background, rationale, methods Can J Aging 18 376 387
29. LJ Melton III CS Crowson WM O'Fallon HW Wahner BL Riggs 2003 Relative contributions of bone density, bone turnover and clinical risk factors to long-term fracture prediction J Bone Miner Res 18 312 318
30. LJ Melton III EJ Atkinson MK O'Connor WM O'Fallon BL Riggs 1998 Bone density and fracture risk in men J Bone Miner Res 13 1915 1923
31. EV [tmp] McCloskey M Beneton D Charlesworth K Kayan D deTakats A Dey, et al. 2007 Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: results of a double-blind, placebo-controlled randomized study J Bone Miner Res 22 135 141
32. G Jones TV Nguyen PN Sambrook PJ Kelly C Gilbert JA Eisman 1994 Symptomatic fracture incidence in elderly men and women. The Dubbo Osteoporosis Epidemiology Study DOES Osteoporos Int 4 277 282
33. A Svanborg 1977 70 year old people in Gothenburg. A population study in an industrialised Swedish city. II. Journal presentation of social and medical conditions Acta Med Scand 611 suppl 5
34. C Johansson D Black O Johnell A Oden D Mellstrom 1998 Bone mineral density is a predictor of survival Calcif Tissue Int 63 190 196
35. S Fujiwara F Kasagi M Yamada K Kodama 1997 Risk factors for hip fracture in Japanese cohort J Bone Miner Res 12 998 1004
36. S Fujiwara K Fumiyoshi W Masunari K Narito G Suzuki M Fukunagi 2003 Fracture prediction from bone mineral density in Japanese men and women J Bone Miner Res 18 1547 1553
37. JA Kanis O Johnell C De Laet B Jonsson A Oden A Oglesby 2002 International variations in hip fracture probabilities: implications for risk assessment J Bone Miner Res 17 1237 1244
38. National Osteoporosis Foundation (NOF) (2003) Physician's Guide to prevention and treatment of osteoporosis. National Osteoporosis Foundation, Washington, DC ( http://www.nof.org/physguide/Physicians-Guide.pdf )
39. JA Kanis F Borgstrom N Zethraeus O Johnell A Oden B Jonsson 2005 Intervention thresholds for osteoporosis in the UK Bone 36 22 32
40. H Johansson A Oden O Johnell B Jonsson C De Laet A Oglesby, et al. 2004 Optimisation of BMD measurements to identify high risk groups for treatment-a test analysis J Bone Miner Res 19 906 913
41. F Borgstrom O Johnell JA Kanis B Jonsson C Renhberg 2006 At what hip fracture risk is it cost-effective to treat? International intervention thresholds for the treatment of osteoporosis Osteoporos Int 17 1459 1471
42. JJ Deeks DG Altman 2004 Diagnostic tests 4: likelihood ratios Br Med J 329 168 169
43. J Brown RG Josse The Scientific Advisory Council of the Osteoporosis Society of Canada 2002 Clinical practice guidelines for the diagnosis and management of osteoporosis in Canada Canad Med Assoc J 167 suppl 10 S1 S34
44. Community European (1998) Report on osteoporosis in the European Community. EC, Strasbourg
45. JA Kanis N Burlet C Cooper On behalf of the European Society for Clinical, Economic Aspects of Osteoporosis, Osteoarthritis (ESCEO), et al. 2008 European guidance for the diagnosis and management of osteoporosis in postmenopausal women Osteoporos Int 19 399 428
46. JA Kanis 2002 Diagnosis of osteoporosis and assessment of fracture risk Lancet 359 1929 1936
47. C De Laet A Oden O Johnell B Jonsson JA Kanis 2005 The impact of the use of multiple risk factors on case finding strategies: a mathematical framework Osteoporos Int 16 313 318
48. E [tmp] McCloskey H Johansson A Oden T Jalava J Kanis 2008 Efficacy of clodronate on fracture risk in women selected by 10-year fracture probability J Bone Miner Res 22 1 S17
49. Kanis JA, Johansson H, Oden A, McCloskey EV (2008) Bazedoxifene reduces vertebral and clinical fractures in postmenopausal women at high risk assessed with FRAX®. Bone, in press
50. JA Kanis A Oden O Johnell B Jonsson C De Laet A Dawson 2001 The burden of osteoporotic fractures: a method for setting intervention thresholds Osteoporos Int 12 417 427