Elicitation of pharmacologically active substances in an intact medical plant

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 17, 2009, Pages 7907-7911

  Kuzel, Stanislav ^a   Vydra, J A N ^a   Triska, J A N ^b   Vrchotova, Nadezda ^b   Hruby, Martin ^c   Cigler, Petr ^a,d  

^a UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

^b INSTITUTE OF MATHEMATICS   (Czech Republic)

^c INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Echinacea purpurea; Ellcitation; Medical plant; Phenolics; Secondary metabolite; Soil; foliar application

Indexed keywords

ASCORBIC ACID; CAFFEIC ACID DERIVATIVE; PHENOL DERIVATIVE; RUTOSIDE; SALICYLIC ACID DERIVATIVE; TITANIUM;

ARTICLE; CHEMISTRY; DRUG EFFECT; ECHINACEA; GROWTH, DEVELOPMENT AND AGING;

ASCORBIC ACID; CAFFEIC ACIDS; ECHINACEA; PHENOLS; RUTIN; SALICYLIC ACIDS; TITANIUM;

ECHINACEA (ASTERACEAE); ECHINACEA PURPUREA;

EID: 69949125651     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf9011246     Document Type: Article

References (41)

1. Balunas, M. J.; Kinghorn, A. D. Drug discovery from medicinal plants. Life Sci. 2005, 78, 431-441.
2. Kolewe, M. E.; Gaurav, V.; Roberts, S. C. Pharmaceutically active natural product synthesis and supply via plant cell culture technology. Mol. Pharm. 2008, 5, 243-256.
3. Sudha, G.; Ravishankar, G. A. Involvement and interaction of various signaling compounds on the plant metabolic events during defense response, resistance to stress factors, formation of secondary metabolites and their molecular aspects. Plant Cell, Tissue Organ Cult. 2002, 71, 181-212.
4. Szpitter, A.; Krolicka, A. Stimulating effect of biotic elicitors on the production of pharmacologically active secondary metabolites in plant in vitro cultures. Biotechnologia 2005, 4, 82-108.
5. Namdeo, A. G. Plant cell elicitation for production of secondary metabolites: a review. Pharmacogn. Rev. 2007, 1, 69-79.
6. Poulev, A.; O'Neal, J. M.; Logendra, S.; Pouleva, R. B.; Timeva, V.; Garvey, A. S.; Gleba, D.; Jenkins, I. S.; Halpern, B. T.; Kneer, R.; Cragg, G. M.; Raskin, I. Elicitation, a new window into plant chemodiversity and phytochemical drug discovery. J. Med. Chem. 2003, 46, 2542-2547.
7. Cigler, P.; Hruby, M.; Kuzel, S. Preparation for induction of increased production of bioactive compounds in plants. International Patent WO 2005118508.
8. (8) Zhang, B.; Hettiarachchy, N.; Chen, P.; Horax, R.; Cornelious, B.; Zhu, D. Influence of the application of three different elicitors on soybean plants on the concentrations of several isoflavones in soybean seeds. J. Agrie. Food Chem. 2006, 54, 5548-5554. (Pubitemid 44195739)
9. Sivesind, E.; Seguin, P. Effects of foliar application of elicitors on red clover isoflavone content. J. Agron. Crop Sci. 2006, 192, 50-54.
10. (10) Hudec, J.; Bakos, D.; Mravec, D.; Kobida, L.; Burdova, M.; Turianica, I.; Hlusek, J. Content of phenolic compounds and free polyamines in black chokeberry {Aronia melanocarpa) after application of polyamine biosynthesis regulators. J. Agrie. Food Chem. 2006, 54, 3625-3628. (Pubitemid 43844190)
11. Hudec, J.; Kochanova, R.; Burdova, M.; Kobida, L.; Kogan, G.; Turianica, I.; Chlebo, P.; Hanackova, E.; Slamka, P. Regulation of the phenolic profile of berries can increase their antioxidant activity. J. Agric. Food Chem. 2009, 57, 2022-2029.
12. (12) Hudec, J.; Burdova, M.; Kobida, L.; Komora, L.; Macho, V.; Kogan, G.; Turianica, I.; Kochanova, R.; Lozek, O.; Haban, M.; Chlebo, P. Antioxidant capacity changes and phenolic profile of Echinacea purpurea, nettle {Urtica dioica L.), and dandelion {Taraxacum officinale) after application of polyamine and phenolic biosynthesis regulators. J. Agrie. Food Chem. 2007, 55, 5689-5696. (Pubitemid 47092944)
13. Barnes, J.; Anderson, L. A.; Gibbons, S.; Phillipson, J. D. Echinacea species {Echinacea angustifolia (DC.) hell., Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties. J. Pharm. Pharmacol. 2005, 57, 929-954.
14. Dalby-Brown, L.; Barsett, H.; Landbo, A. K.; Meyer, A. S.; Molgaard, P. Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins. J. Agrie. Food Chem. 2005, 53, 9413-9423.
15. Vrchotova, N.; Kuzel, S.; Triska, J.; Kolar, L.; Totusek, J. Extraction and analysis of phenolic compounds from Echinacea purpurea (L.) Moench. Chem. Listy 2002, 96, 636-639.
16. Binns, S. E.; Livesey, J. F.; Arnason, J. T.; Baum, B. R. Phytochemical variation in Echinacea from roots and flowerheads of wild and cultivated populations. J. Agric. Food Chem. 2002, 50, 36733687.
17. Deschamps, C.; Raskin, I.; Simon, J. E. Regulation of essential oil accumulation in basil {Ocimum basilicum L.) in response to elicitation. Int. J. Plant Sei. {Chicago, IL) 2008, 169, 981-986.
18. - ratios and watering regimes. Can. J. Plant Sei. 2006, 86, 809-815.
19. Zheng, Y.; Jones, M. P. A.; Dixon, M. A.; Saxena, P. K. Conventional and emerging cultivation strategies for medicinal Echinacea production. In Advances in Medicinal Plant Research; Acharya, S. N., Thomas, J. E., Eds.; Research Signpost: Kerala, India, 2007; pp 513528.
20. Zheng, Y.; Dixon, M.; Saxena, P. K. Growing environment and nutrient availability affect the content of some phenolic compounds in Echinacea purpurea and Echinacea angustifolia. Planta Med. 2006, 72, 1407-1414.
21. (21) Kirakosyan, A.; Kaufman, P. B.; Chang, S. C.; Warber, S.; Boiling, S.; Vardapetyan, H. Regulation of isoflavone production in hydroponically grown Pueraria montana (kudzu) by cork pieces, XAD-4, and methyl jasmonate. Plant Cell Rep. 2006, 25,1387-1391. (Pubitemid 44786621)
22. (22) Kneer, R.; Poulev, A. A.; Olesinski, A.; Raskin, I. Characterization of the elicitor-induced biosynthesis and secretion of genistein from roots of Lupinus luteus L. J. Exp. Bot. 1999, 50, 1553-1559. (Pubitemid 129520105)
23. Shotipruk, A.; Wang, H. Y.; Kaufman, P. B. Production of secondary metabolites of medicinal value from plants using a two-stage programmable photobioreactor. Recent Prog. Med. Plants 2004, 4, 225-236.
24. Smetanska, I.; Krumbein, A.; Schreiner, M.; Knorr, D. Influence of salicylic acid and methyl jasmonate on glucosinolate levels in turnip. J. Hortic. Sci. Biotechnol. 2007, 82, 690-694.
25. (25) Koroch, A.; Juliani, H. R.; Kapteyn, J.; Simon, J. E. In vitro regeneration of Echinacea purpurea from leaf expiants. Plant Cell, Tissue Organ Cult. 2002, 69, 79-83. (Pubitemid 34432021)
26. Abbasi, B. H.; Saxena, P. K.; Murch, S. J.; Liu, G Z. Echinacea biotechnology: challenges and opportunities. In Vitro Cell. Dev. Biol.: Plant 2007, 43, 481-492.
27. Pan, Z. G.; Liu, G Z.; Zobayed, S. M. A.; Saxena, P. K. Plant regeneration from mesophyll protoplasts of Echinacea purpurea. Plant Cell, Tissue Organ Cult. 2004, 77, 251-255.
28. Zobayed, S. M. A.; Saxena, P. K. In vitro regeneration of Echinacea purpurea L.: enhancement of somatic embryogenesis by indolebutyric acid and dark pre-incubation. In Vitro Cell. Dev. Biol.: Plant 2003, 39, 605-612.
29. Pais, I. The biological importance of titanium. J. Plant Nutr. 1983, 6, 3-131.
30. (30) Hruby, M.; Cigler, P.; Kuzel, S. Contribution to understanding the mechanism of titanium action in plant. J. Plant Nutr. 2002, 25, 577598. (Pubitemid 34271453)
31. Kuzel, S.; Hruby, M.; Cigler, P.; Tlustos, P.; Van, P. N. Mechanism of physiological effects of titanium leaf sprays on plants grown on soil. Biol. Trace Elem. Res. 2003, 91, 179-189.
32. (32) Tlustos, P.; Cigler, P.; Hruby, M.; Kuzel, S.; Szakova, J.; Balik, J. The role of titanium in biomass production and its influence on essential elements' contents in field growing crops. Plant, Soil Environ. 2005, 51, 19-25. (Pubitemid 40323388)
33. (33) Kuzel, S.; Cigler, P.; Hruby, M.; Vydra, J.; Pavlikova, D.; Tlustos, P. The effect of simultaneous magnesium application on the biological effects of titanium. Plant, Soil Environ. 2007, 53, 16-23. (Pubitemid 46192145)
34. Stebbing, A. R. A theory for growth hormesis. Mutat. Res. 1998, 403, 249-258.
35. Heil, M.; Ton, J. Long-distance signalling in plant defence. Trends Plant Sci. 2008, 13, 264-272.
36. Gray, D. E.; Pallardy, S. G.; Garrett, H. E.; Rottinghaus, G. E. Acute drought stress and plant age effects on alkamide and phenolic acid content in purple coneflower roots. Planta Med. 2003, 69, 50-55.
37. Montanari, M.; Degl'nnocenti, E.; Maggini, R.; Pacifici, S.; Pardossi, A.; Guidi, L. Effect of nitrate fertilization and saline stress on the contents of active constituents of Echinacea angustifolia DC. Food Chem. 2007, 107, 1461-1466.
38. (38) Kolar, L.; Ledvina, L.; Kuzel, S.; Pasek, J. The effect of nitrogen surplus in fertilizing rates applied to Echinacea purpurea on the production of its active substances. Rostl. Vyroba 1998, 44, 489-495. (Pubitemid 128161590)
39. Li, W. W.; Barz, W. Structure and accumulation of phenolics in elicited Echinacea purpurea cell cultures. Planta Med. 2006, 72, 248254.
40. Wu, C. H.; Tewari, R. K.; Hahn, E. J.; Paek, K. Y. Nitric oxide elicitation induces the accumulation of secondary metabolites and antioxidant defense in adventitious roots of Echinacea purpurea. J. Plant Biol. 2007, 50, 636-643.
41. Liu, C. Z.; Abbasi, B. H.; Gao, M.; Murch, S. J.; Saxena, P. K. Caffeic acid derivatives production by hairy root cultures of Echinacea purpurea. J. Agrie. Food Chem. 2006, 54, 8456-8460.