Pharmacological targeting of native CatSper channels reveals a required role in maintenance of sperm hyperactivation

PLoS ONE

Volumn 4, Issue 8, 2009, Pages

  Carlson, Anne E ^a   Burnett, Lindsey A ^a   del Camino, Donato ^b   Quill, Timothy A ^c   Hille, Bertil ^a   Chong, Jayhong A ^b   Moran, Magdalene M ^b   Babcock, Donner F ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Hydra Biosciences   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 BIS(2 THIENYLCARBONYL) 1,2,5 OXADIAZOLE 2 IUM 2 OLATE; AMMONIUM CHLORIDE; BICARBONATE; CALCIUM ION; CATSPER CHANNEL 1; CATSPER CHANNEL 2; CATSPER CHANNEL 3; CATSPER CHANNEL 4; FURA 2; HC 056456; ION CHANNEL; ION TRANSPORT AFFECTING AGENT; PROPIONIC ACID; SODIUM ION; UNCLASSIFIED DRUG; CALCIUM; CALCIUM CHANNEL; CATSPER1 PROTEIN, MOUSE; SODIUM;

ACIDIFICATION; ALKALINIZATION; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL ACTIVATION; CELL POPULATION; DEPOLARIZATION; DRUG MECHANISM; DRUG TARGETING; HIGH THROUGHPUT SCREENING; ION CURRENT; MALE; MOUSE; NONHUMAN; PATCH CLAMP; PROTEIN FUNCTION; SODIUM TRANSPORT; SPERM; SPERMATOZOON CAPACITATION; SPERMATOZOON MOTILITY; ANIMAL; DRUG EFFECT; ION TRANSPORT; METABOLISM; SPERMATOZOON;

ANIMALS; CALCIUM; CALCIUM CHANNELS; ION TRANSPORT; MALE; MICE; SODIUM; SPERMATOZOA;

EID: 69949116363     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006844     Document Type: Article

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