TNF-α/IL-10 ratio and C-reactive protein as markers of the inflammatory response in CAD-prone North Indian patients with acute myocardial infarction

Clinica Chimica Acta

Volumn 408, Issue 1-2, 2009, Pages 14-18

  Goswami, Binita ^a   Rajappa, Medha ^b   Mallika, V ^a   Shukla, Deepak Kumar ^c   Kumar, Suresh ^d  

^a G B PANT HOSPITAL   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c INDIAN COUNCIL OF MEDICAL RESEARCH   (India)

^d LOK NAYAK HOSPITAL   (India)

Author keywords

Coronary artery disease; Cytokines; Inflammation; Interleukin 10 (IL 10); Tumor necrosis factor (TNF )

Indexed keywords

APOLIPOPROTEIN A; APOLIPOPROTEIN B; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CYTOKINE; INTERLEUKIN 10; LIPID; TUMOR NECROSIS FACTOR ALPHA;

ACUTE HEART INFARCTION; ADULT; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; INDIAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL;

BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; FEMALE; HUMANS; INDIA; INFLAMMATION; INTERLEUKIN-10; LIPID METABOLISM; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; REGRESSION ANALYSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 69849089255     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2009.06.029     Document Type: Article

References (47)

1. Libby P., Ridker P.M., and Maseri A. Inflammation and atherosclerosis. Circulation 105 (2002) 1135-1143
2. Mallika V., Goswami B., and Rajappa M. Atherosclerosis- pathophysiology and the role of novel risk factors: a clinicobiochemical perspective. Angiology 58 (2007) 513-522
3. Davies M.J. Stability and instability: the two faces of coronary atherosclerosis. Circulation 94 (1996) 2013-2020
4. Plutzky J. Inflammatory pathways in atherosclerosis and acute coronary syndrome. Am J Cardiol 88 suppl (2001) 10K-15K
5. Girn H.R.S., Orbi N.M., and Homer-Vanniasinkam S. An overview of cytokine interactions in atherosclerosis and implications for peripheral artery disease. Vasc Med 12 (2007) 299-309
6. Tedgui A., and Mallat Z. Cytokines in atherosclerosis: pathogenic and pathways. Physiol Rev 86 (2006) 515-581
7. Larrick J.W., and Wright S.C. Cytotoxic mechanism of tumour necrosis factor-alpha. FASEB J 4 (1990) 3215-3223
8. Feldman A.M., Combes A., Wagner D., Kadakomi T., Kuboka T., Li Y.Y., and McTrernan C. The role of tumour necrosis factor in the pathophysiology of heart failure. J Am Coll Cardiol 35 (2000) 537-544
9. Ridker P.M., Rifai N., Pfiffer M., and Sacks F. Elevation of tumour necrosis factor α and increased risk of recurrent coronary events after myocardial infarction. Circulation 101 (2000) 2149-2153
10. Mallat Z., Besnard S., Duriez M., et al. Protective role of interleukin-10 in atherosclerosis. Circ Res 85 (1999) e17-e24
11. Wang P., Wu P., and Siegel M.I. Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes: IL-10 and IL-4 suppress cytokine synthesis by different mechanisms. J Biol Chem 270 (1995) 9558-9563
12. Fichtlscherer S., Breurer S., Heeschen C., Dimmeler S., and Zeiher A.M. Interleukin-10 serum concentrations and systemic endothelial vasoreactivity in patients of coronary artery disease. J Am Coll Cardiol 44 (2004) 44-49
13. Jilal I., Devraj S., and Venugopal S. C-reactive protein: risk maker or mediator in atherothrombosis. Hypertens 44 (2004) 6-16
14. Torzewski J. C-reactive protein and atherogenesis. New insight from established animal models. Am J Pathol 167 (2005) 923-925
15. Torzewski M., Rist C., Mortensen R.F., and Zwaka T.P. C-reactive protein in the arterial intima. Role of C-reactive protein receptor dependent monocyte recruitment in atherogenesis. Arterioscler Thromb Vasc Biol 20 (2000) 2094-2099
16. Fichtscherer S., Rosmbingr G., Walter D.H., and Breur S. Increased C-reactive protein and improved endothelial reactivity in patents with coronary artery disease. Circulation 102 (2000) 1000-1016
17. Venugopalan S.K., Devaraj S., Yuhana I., and Shaul P. Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells. Circulation 106 (2002) 1439-1441
18. Zwaka T.P., Hombach V., and Torzewski J. C-reactive protein mediated low density lipoprotein uptake by macrophages: implications for atherosclerosis. Circulation 103 (2001) 1194-1197
19. Cermark J., Key N., Bach R., and Balla J. C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor. Blood 82 (1993) 513-520
20. Alpert J.S., Thygesen K., Antman E., and Barband J.P. Myocardial infarction redefined- a consensus document of the joint European Society of Cardiology/ American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 36 (2000) 959-969
21. Schillinger M., Exner M., Mlekusch W., et al. Inflammation and Carotid Artery- Risk for Atherosclerosis Study (ICARAS). Circulation 111 (2005) 2203-2209
22. American Diabetic Association. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 20 (1997) 1183-1201
23. Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 18 (1972) 499-502
24. Libby P. Vascular biology of atherosclerosis overview and state of the art. Am J Cardiol 91 Suppl (2003) 3A-6A
25. Rajappa M., Sridhar M.G., Balachander J., and Sethuraman K.R. Lipoprotein (a) and comprehensive lipid tetrad index as a marker for coronary artery disease in NIDDM patients in South India. Clin Chim Acta 372 (2006) 70-75
26. Rajappa M., and Sharma A. Biomarkers of cardiac injury: an update. Angiol J Vasc Dis 56 (2005) 677-691
27. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 340 (1999) 115-126
28. Mazzone A., De Servi S., Ricevuti G., et al. Increased expression of neutrophil and monocyte adhesion molecules in unstable coronary artery disease. Circulation 88 (1993) 358-363
29. Biasucci L.M., Colizzi C., Rizzello V., Vitrella G., Crea F., and Liuzzo G. Role of inflammation in the pathogenesis of unstable coronary artery diseases. Scand J Clin Lab Invest Suppl. 230 (1999) 12-22
30. Girndt M., and Kohler H. Interleukin-10: an update on its relevance for cardiovascular risk. Nephrol Dial Transplant 18 (2003) 1976-1979
31. Varadhachary A.S., Monestier M., and Salgame P. Reciprocal induction of IL-10 and IL-12 from macrophages by low-density lipoprotein and its oxidized forms. Cell Immunol 213 (2001) 45-51
32. Fu T., and Borensztajn J. Macrophage uptake of low-density lipoprotein bound to aggregated C-reactive protein: possible mechanism of foam-cell formation in atherosclerotic lesions. Biochem J 366 (2002) 195-201
33. Ridker P.M., Rifai N., Pfiffer M., and Sacks F. Elevation of tumour necrosis factor α and increased risk of recurrent coronary events after myocardial infarction. Circulation 101 (2000) 2149-2153
34. Cesari M., Penninx B.W.J.H., Pahor M., Lauretani F., Corsi A.M., Williams G.R., Guralnik J.M., and Ferruci L. Inflammatory markers and physical performance in older persons. The InCHIANTI Study. J Gerontol Ser A Biol Med Sci 59 (2004) M242-M248
35. Terkeltaub R.A. IL-10: an "immunologic scalpel" for atherosclerosis?. Arterioscler Thromb Vasc Biol 19 (1999) 2823-2825
36. Anguera I., Miranda-Guardiola F., Bosch X., et al. Elevation of serum concentrations of the anti-inflammatory cytokine interleukin-10 and decreased risk of coronary events in patients with unstable angina. Am Heart J 144 (2002) 811-817
37. Heeschen C., Dimmeier S., Hamm C.W., Fichtlscherer S., Boersma E., Simoons M.L., and Zeiher A.M. Serum concentrations of the anti inflammatory cytokine interleukin-10 is an important prognostic determinant in patients with acute coronary syndromes. Circulation 107 (2003) 2109-2114
38. Kobayashi S., Inoue N., Ohashi Y., et al. Interaction of oxidative stress and inflammatory response in coronary plaque instability. Arterioscler Thromb Vasc Biol 23 (2003) 1398-1403
39. Lloyd-Jones D., Liu K., Tian L., and Greenland P. Assessment of C-reactive protein in risk prediction for cardiovascular disease. Ann Int Med 145 1 (2006) 35-42
40. Koenig W., Khuseyinova N., Baumert J., Thorand B., Loewel H., Chambless L., Meisinger C., Scheinder A., Martin S., Hubert K., and Herder C. Increased concentration of C-reactive protein and IL-6 but not IL-18 are independently associated with incident coronary events in middle aged men and women. Arterioscler Thromb Vasc Biol 26 (2006) 2745-2751
41. Clearfield M. C-reactive protein: a new risk assessment tool for cardiovascular disease. J Am Orth Assoc 105 9 (2005) 409-416
42. Kinjo K., Sato H., Ohnishi Y., and Hishida E. Impact of high sensitivity C-reactive protein on predicting long term mortality of acute myocardial infarction. Am J Cardiol 91 (2003) 931-935
43. St Pierre A.C., Bergeron J., Pirro M., and Cantin B. Effect of plasma C-reactive protein concentrations in modulating the risk of coronary heart disease associated with small dense, low density lipoproteins in men. Am J Cardiol 91 (2003) 555-558
44. Cabana V.G., Seigel J.N., and Sabesin S.M. Effect of acute phase response on the concentration and density distribution of plasma lipids and apolipoproteins. J Lipid Res 30 (1989) 39-49
45. Feingold K.R., Memon R.A., Moser A.H., and Grunfeld C. Paraoxonase activity in the serum and hepatic mRNA concentrations decrease during the acute phase response. Atherosclerosis 139 (1998) 307-315
46. Waehre R., Halvorsen B., Damas J.K., et al. Inflammatory imbalance between IL-10 and TNF alpha in unstable angina: potential plaque stabilizing effects of IL-10. Eur J Clin Invest 32 (2002) 803-810
47. Rajappa M., Sen S.K., and Sharma A. Role of pro-/anti-inflammatory cytokines and their correlation with established risk factors in South Indians with coronary artery disease. Angiology (2008) Sep 15. [Electronic publication ahead of print.]