-
1
-
-
0036183221
-
Im7 folding mechanism: misfolding on a path to the native state
-
Capaldi A.P., Kleanthous C., and Radford S.E. Im7 folding mechanism: misfolding on a path to the native state. Nat. Struct. Biol. 9 (2002) 209-216
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 209-216
-
-
Capaldi, A.P.1
Kleanthous, C.2
Radford, S.E.3
-
2
-
-
62049084565
-
The mechanism of folding of Im7 reveals competition between functional and kinetic evolutionary constraints
-
Friel C.T., Smith D.A., Vendruscolo M., Gsponer J., and Radford S.E. The mechanism of folding of Im7 reveals competition between functional and kinetic evolutionary constraints. Nat. Struct. Mol. Biol. 16 (2009) 318-324
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 318-324
-
-
Friel, C.T.1
Smith, D.A.2
Vendruscolo, M.3
Gsponer, J.4
Radford, S.E.5
-
3
-
-
0035170463
-
Ultrarapid mixing experiments reveal that Im7 folds via an on-pathway intermediate
-
Capaldi A.P., Shastry M.C., Kleanthous C., Roder H., and Radford S.E. Ultrarapid mixing experiments reveal that Im7 folds via an on-pathway intermediate. Nat. Struct. Biol. 8 (2001) 68-72
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 68-72
-
-
Capaldi, A.P.1
Shastry, M.C.2
Kleanthous, C.3
Roder, H.4
Radford, S.E.5
-
4
-
-
30444450687
-
Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7
-
Gsponer J., Hopearuoho H., Whittaker S.B.-M., Spence G.R., Moore G.R., Paci E., et al. Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7. Proc. Natl Acad. Sci. USA 103 (2006) 99-104
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 99-104
-
-
Gsponer, J.1
Hopearuoho, H.2
Whittaker, S.B.-M.3
Spence, G.R.4
Moore, G.R.5
Paci, E.6
-
5
-
-
4143080376
-
Trapping the on-pathway folding intermediate of Im7 at equilibrium
-
Spence G.R., Capaldi A.P., and Radford S.E. Trapping the on-pathway folding intermediate of Im7 at equilibrium. J. Mol. Biol. 341 (2004) 215-226
-
(2004)
J. Mol. Biol.
, vol.341
, pp. 215-226
-
-
Spence, G.R.1
Capaldi, A.P.2
Radford, S.E.3
-
6
-
-
33846577660
-
NMR analysis of the conformational properties of the trapped on-pathway folding intermediate of the bacterial immunity protein Im7
-
Whittaker S.B.-M., Spence G.R., Gunter Grossmann J., Radford S.E., and Moore G.R. NMR analysis of the conformational properties of the trapped on-pathway folding intermediate of the bacterial immunity protein Im7. J. Mol. Biol. 366 (2007) 1001-1015
-
(2007)
J. Mol. Biol.
, vol.366
, pp. 1001-1015
-
-
Whittaker, S.B.-M.1
Spence, G.R.2
Gunter Grossmann, J.3
Radford, S.E.4
Moore, G.R.5
-
7
-
-
14644404941
-
Ultraviolet resonance Raman studies reveal the environment of tryptophan and tyrosine residues in the native and partially folded states of the E colicin-binding immunity protein Im7
-
Rodriguez-Mendieta I.R., Spence G.R., Gell C., Radford S.E., and Smith D.A. Ultraviolet resonance Raman studies reveal the environment of tryptophan and tyrosine residues in the native and partially folded states of the E colicin-binding immunity protein Im7. Biochemistry 44 (2005) 3306-3315
-
(2005)
Biochemistry
, vol.44
, pp. 3306-3315
-
-
Rodriguez-Mendieta, I.R.1
Spence, G.R.2
Gell, C.3
Radford, S.E.4
Smith, D.A.5
-
8
-
-
38049140954
-
Consequences of localized frustration for the folding mechanism of the IM7 protein
-
Sutto L., Latzer J., Hegler J.A., Ferreiro D.U., and Wolynes P.G. Consequences of localized frustration for the folding mechanism of the IM7 protein. Proc. Natl Acad. Sci. USA 104 (2007) 19825-19830
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 19825-19830
-
-
Sutto, L.1
Latzer, J.2
Hegler, J.A.3
Ferreiro, D.U.4
Wolynes, P.G.5
-
9
-
-
4143061715
-
Switching two-state to three-state kinetics in the helical protein Im9 via the optimisation of stabilising non-native interactions by design
-
Friel C.T., Beddard G.S., and Radford S.E. Switching two-state to three-state kinetics in the helical protein Im9 via the optimisation of stabilising non-native interactions by design. J. Mol. Biol. 342 (2004) 261-273
-
(2004)
J. Mol. Biol.
, vol.342
, pp. 261-273
-
-
Friel, C.T.1
Beddard, G.S.2
Radford, S.E.3
-
10
-
-
0032127769
-
A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity
-
Dennis C.A., Videler H., Pauptit R.A., Wallis R., James R., Moore G.R., and Kleanthous C. A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity. Biochem. J. 333 (1998) 183-191
-
(1998)
Biochem. J.
, vol.333
, pp. 183-191
-
-
Dennis, C.A.1
Videler, H.2
Pauptit, R.A.3
Wallis, R.4
James, R.5
Moore, G.R.6
Kleanthous, C.7
-
11
-
-
0031038377
-
Local interactions in protein folding: lessons from the alpha-helix
-
Aurora R., Creamer T.P., Srinivasan R., and Rose G.D. Local interactions in protein folding: lessons from the alpha-helix. J. Biol. Chem. 272 (1997) 1413-1416
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1413-1416
-
-
Aurora, R.1
Creamer, T.P.2
Srinivasan, R.3
Rose, G.D.4
-
12
-
-
0028447768
-
Elucidating the folding problem of helical peptides using empirical parameters
-
Munoz V., and Serrano L. Elucidating the folding problem of helical peptides using empirical parameters. Nat. Struct. Biol. 1 (1994) 399-409
-
(1994)
Nat. Struct. Biol.
, vol.1
, pp. 399-409
-
-
Munoz, V.1
Serrano, L.2
-
13
-
-
0030816685
-
Mechanism of helix induction by trifluoroethanol: a framework for extrapolating the helix-forming properties of peptides from trifluoroethanol/water mixtures back to water
-
Luo P., and Baldwin R.L. Mechanism of helix induction by trifluoroethanol: a framework for extrapolating the helix-forming properties of peptides from trifluoroethanol/water mixtures back to water. Biochemistry 36 (1997) 8413-8421
-
(1997)
Biochemistry
, vol.36
, pp. 8413-8421
-
-
Luo, P.1
Baldwin, R.L.2
-
16
-
-
0033012736
-
C-terminal capping motifs in model helical peptides
-
Kallenbach N.R., and Gong Y. C-terminal capping motifs in model helical peptides. Bioorg. Med. Chem. 7 (1999) 143-151
-
(1999)
Bioorg. Med. Chem.
, vol.7
, pp. 143-151
-
-
Kallenbach, N.R.1
Gong, Y.2
-
17
-
-
0033080081
-
Is protein folding hierarchic? II. Folding intermediates and transition states
-
Baldwin R.L., and Rose G.D. Is protein folding hierarchic? II. Folding intermediates and transition states. Trends Biochem. Sci. 24 (1999) 77-83
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 77-83
-
-
Baldwin, R.L.1
Rose, G.D.2
-
18
-
-
0032972986
-
Is protein folding hierarchic? I. Local structure and peptide folding
-
Baldwin R.L., and Rose G.D. Is protein folding hierarchic? I. Local structure and peptide folding. Trends Biochem. Sci. 24 (1999) 26-33
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 26-33
-
-
Baldwin, R.L.1
Rose, G.D.2
-
19
-
-
0025911856
-
Surface electrostatic interactions contribute little of stability of barnase
-
Sali D., Bycroft M., and Fersht A.R. Surface electrostatic interactions contribute little of stability of barnase. J. Mol. Biol. 220 (1991) 779-788
-
(1991)
J. Mol. Biol.
, vol.220
, pp. 779-788
-
-
Sali, D.1
Bycroft, M.2
Fersht, A.R.3
-
20
-
-
0028174643
-
Quantitative determination of helical propensities from trifluoroethanol titration curves
-
Jasanoff A., and Fersht A.R. Quantitative determination of helical propensities from trifluoroethanol titration curves. Biochemistry 33 (1994) 2129-2135
-
(1994)
Biochemistry
, vol.33
, pp. 2129-2135
-
-
Jasanoff, A.1
Fersht, A.R.2
-
21
-
-
0016169865
-
Determination of the helix and beta form of proteins in aqueous solution by circular dichroism
-
Chen Y.H., Yang J.T., and Chau K.H. Determination of the helix and beta form of proteins in aqueous solution by circular dichroism. Biochemistry 13 (1974) 3350-3359
-
(1974)
Biochemistry
, vol.13
, pp. 3350-3359
-
-
Chen, Y.H.1
Yang, J.T.2
Chau, K.H.3
-
22
-
-
0030447864
-
Helix propagation and N-cap propensities of the amino acids measured in alanine-based peptides in 40 volume percent trifluoroethanol
-
Rohl C.A., Chakrabartty A., and Baldwin R.L. Helix propagation and N-cap propensities of the amino acids measured in alanine-based peptides in 40 volume percent trifluoroethanol. Protein Sci. 5 (1996) 2623-2637
-
(1996)
Protein Sci.
, vol.5
, pp. 2623-2637
-
-
Rohl, C.A.1
Chakrabartty, A.2
Baldwin, R.L.3
-
23
-
-
0032553332
-
Elucidating the folding problem of alpha-helices: local motifs, long-range electrostatics, ionic-strength dependence and prediction of NMR parameters
-
Lacroix E., Viguera A.R., and Serrano L. Elucidating the folding problem of alpha-helices: local motifs, long-range electrostatics, ionic-strength dependence and prediction of NMR parameters. J. Mol. Biol. 284 (1998) 173-191
-
(1998)
J. Mol. Biol.
, vol.284
, pp. 173-191
-
-
Lacroix, E.1
Viguera, A.R.2
Serrano, L.3
-
24
-
-
0031127043
-
Development of the multiple sequence approximation within the AGADIR model of alpha-helix formation: comparison with Zimm-Bragg and Lifson-Roig formalisms
-
Munoz V., and Serrano L. Development of the multiple sequence approximation within the AGADIR model of alpha-helix formation: comparison with Zimm-Bragg and Lifson-Roig formalisms. Biopolymers 41 (1997) 495-509
-
(1997)
Biopolymers
, vol.41
, pp. 495-509
-
-
Munoz, V.1
Serrano, L.2
-
25
-
-
0035896036
-
Using chimeric immunity proteins to explore the energy landscape for alpha-helical protein folding
-
Ferguson N., Li W., Capaldi A.P., Kleanthous C., and Radford S.E. Using chimeric immunity proteins to explore the energy landscape for alpha-helical protein folding. J. Mol. Biol. 307 (2001) 393-405
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 393-405
-
-
Ferguson, N.1
Li, W.2
Capaldi, A.P.3
Kleanthous, C.4
Radford, S.E.5
-
26
-
-
0030462974
-
Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme
-
Vetter I.R., Baase W.A., Heinz D.W., Xiong J.P., Snow S., and Matthews B.W. Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme. Protein. Sci. 5 (1996) 2399-2415
-
(1996)
Protein. Sci.
, vol.5
, pp. 2399-2415
-
-
Vetter, I.R.1
Baase, W.A.2
Heinz, D.W.3
Xiong, J.P.4
Snow, S.5
Matthews, B.W.6
-
27
-
-
2542599277
-
Phi-value analysis and the nature of protein-folding transition states
-
Fersht A.R., and Sato S. Phi-value analysis and the nature of protein-folding transition states. Proc. Natl Acad. Sci. USA 101 (2004) 7976-7981
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 7976-7981
-
-
Fersht, A.R.1
Sato, S.2
-
28
-
-
0025325983
-
The "megaprimer" method of site-directed mutagenesis
-
Sarkar G., and Sommer S.S. The "megaprimer" method of site-directed mutagenesis. BioTechniques 8 (1990) 404-407
-
(1990)
BioTechniques
, vol.8
, pp. 404-407
-
-
Sarkar, G.1
Sommer, S.S.2
-
29
-
-
0028871804
-
How to measure and predict the molar absorption coefficient of a protein
-
Pace C.N., Vajdos F., Fee L., Grimsley G., and Gray T. How to measure and predict the molar absorption coefficient of a protein. Protein Sci. 4 (1995) 2411-2423
-
(1995)
Protein Sci.
, vol.4
, pp. 2411-2423
-
-
Pace, C.N.1
Vajdos, F.2
Fee, L.3
Grimsley, G.4
Gray, T.5
-
30
-
-
0025752606
-
Side chain-backbone hydrogen bonding contributes to helix stability in peptides derived from an alpha-helical region of carboxypeptidase A
-
Bruch M.D., Dhingra M.M., and Gierasch L.M. Side chain-backbone hydrogen bonding contributes to helix stability in peptides derived from an alpha-helical region of carboxypeptidase A. Proteins 10 (1991) 130-139
-
(1991)
Proteins
, vol.10
, pp. 130-139
-
-
Bruch, M.D.1
Dhingra, M.M.2
Gierasch, L.M.3
-
31
-
-
0030874298
-
Comparison of NH exchange and circular dichroism as techniques for measuring the parameters of the helix-coil transition in peptides
-
Rohl C.A., and Baldwin R.L. Comparison of NH exchange and circular dichroism as techniques for measuring the parameters of the helix-coil transition in peptides. Biochemistry 36 (1997) 8435-8442
-
(1997)
Biochemistry
, vol.36
, pp. 8435-8442
-
-
Rohl, C.A.1
Baldwin, R.L.2
-
32
-
-
0028950079
-
Urea unfolding of peptide helices as a model for interpreting protein unfolding
-
Scholtz J.M., Barrick D., York E.J., Stewart J.M., and Baldwin R.L. Urea unfolding of peptide helices as a model for interpreting protein unfolding. Proc. Natl Acad. Sci. USA 92 (1995) 185-189
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 185-189
-
-
Scholtz, J.M.1
Barrick, D.2
York, E.J.3
Stewart, J.M.4
Baldwin, R.L.5
-
33
-
-
0029400480
-
NMRPipe: a multidimensional spectral processing system based on UNIX pipes
-
Delaglio F., Grzesiek S., Vuister G.W., Zhu G., Pfeifer J., and Bax A. NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J. Biomol. NMR. 6 (1995) 277-293
-
(1995)
J. Biomol. NMR.
, vol.6
, pp. 277-293
-
-
Delaglio, F.1
Grzesiek, S.2
Vuister, G.W.3
Zhu, G.4
Pfeifer, J.5
Bax, A.6
-
34
-
-
34249765651
-
NMR View: a computer program for the visualization and analysis of NMR data J
-
Johnson B., and Blevins R. NMR View: a computer program for the visualization and analysis of NMR data J. Biomol. NMR 4 (1994) 603-614
-
(1994)
Biomol. NMR
, vol.4
, pp. 603-614
-
-
Johnson, B.1
Blevins, R.2
-
35
-
-
0036873589
-
Protein NMR structure determination with automated NOE-identification in the NOESY spectra using the new software ATNOS
-
Herrmann T., Guntert P., and Wuthrich K. Protein NMR structure determination with automated NOE-identification in the NOESY spectra using the new software ATNOS. J. Biomol. NMR 24 (2002) 171-189
-
(2002)
J. Biomol. NMR
, vol.24
, pp. 171-189
-
-
Herrmann, T.1
Guntert, P.2
Wuthrich, K.3
-
36
-
-
0036308102
-
Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA
-
Herrmann T., Guntert P., and Wuthrich K. Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA. J. Mol. Biol. 319 (2002) 209-227
-
(2002)
J. Mol. Biol.
, vol.319
, pp. 209-227
-
-
Herrmann, T.1
Guntert, P.2
Wuthrich, K.3
-
37
-
-
0031576336
-
Torsion angle dynamics for NMR structure calculation with the new program DYANA
-
Guntert P., Mumenthaler C., and Wuthrich K. Torsion angle dynamics for NMR structure calculation with the new program DYANA. J. Mol. Biol. 273 (1997) 283-298
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 283-298
-
-
Guntert, P.1
Mumenthaler, C.2
Wuthrich, K.3
-
40
-
-
0030339738
-
AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR
-
Laskowski R.A., Rullmann J.A.C., MacArthur M.W., Kaptein R., and Thornton J.M. AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR. J. Biomol. NMR 8 (1996) 477-486
-
(1996)
J. Biomol. NMR
, vol.8
, pp. 477-486
-
-
Laskowski, R.A.1
Rullmann, J.A.C.2
MacArthur, M.W.3
Kaptein, R.4
Thornton, J.M.5
-
41
-
-
0025398721
-
WHAT IF-a molecular modeling and drug design program
-
Vriend G. WHAT IF-a molecular modeling and drug design program. J. Mol. Graphics 8 (1990) 52-56
-
(1990)
J. Mol. Graphics
, vol.8
, pp. 52-56
-
-
Vriend, G.1
-
42
-
-
4444221565
-
UCSF Chimera-a visualization system for exploratory research and analysis
-
Pettersen E.F., Goddard T.D., Huang C.C., Couch G.S., Greenblatt D.M., Meng E.C., and Ferrin T.E. UCSF Chimera-a visualization system for exploratory research and analysis. J. Comput. Chem. 25 (2004) 1605-1612
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
-
43
-
-
1442351134
-
Equilibrium hydrogen exchange reveals extensive hydrogen bonded secondary structure in the on-pathway intermediate of Im7
-
Gorski S.A., Le Duff C.S., Capaldi A.P., Kalverda A.P., Beddard G.S., Moore G.R., and Radford S.182E. Equilibrium hydrogen exchange reveals extensive hydrogen bonded secondary structure in the on-pathway intermediate of Im7. J. Mol. Biol. 337 (2004) 183-193
-
(2004)
J. Mol. Biol.
, vol.337
, pp. 183-193
-
-
Gorski, S.A.1
Le Duff, C.S.2
Capaldi, A.P.3
Kalverda, A.P.4
Beddard, G.S.5
Moore, G.R.6
Radford, S.182E.7
|