Thiopental pharmacokinetics in newborn infants: A case report of overdose

Acta Paediatrica, International Journal of Paediatrics

Volumn 98, Issue 10, 2009, Pages 1680-1682

  Norman, Elisabeth ^a   Malmqvist, Ulf ^a   Westrin, Per ^a   Fellman, Vineta ^a,b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Intubation; Neonates; Overdose; Premedication; Sedation

Indexed keywords

ACICLOVIR; ANTIBIOTIC AGENT; CARNITINE; CYANOCOBALAMIN; ELECTROLYTE; PYRIDOXINE; SODIUM CHLORIDE; SURFACTANT; THIOPENTAL; VITAMIN B COMPLEX;

APGAR SCORE; ARTICLE; BIRTH WEIGHT; BLEEDING; BLOOD GAS ANALYSIS; CASE REPORT; CESAREAN SECTION; DRUG OVERDOSE; DRUG SAFETY; ELECTROCARDIOGRAPHY; ELECTROENCEPHALOGRAPHY; ENTERIC FEEDING; ERYTHROCYTE TRANSFUSION; GESTATIONAL AGE; HEMODYNAMICS; HOSPITAL DISCHARGE; HUMAN; HYPOTENSION; INTRAVENOUS CATHETER; INTUBATION; MALE; MEAN ARTERIAL PRESSURE; MUSCLE HYPOTONIA; MUSCLE RELAXATION; NEONATAL RESPIRATORY DISTRESS SYNDROME; NEUROIMAGING; NEWBORN; NEWBORN INTENSIVE CARE; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN SATURATION; OXYGEN TRANSPORT; PREMATURITY; PREMEDICATION; PRIORITY JOURNAL; PSYCHOMOTOR DEVELOPMENT; REM SLEEP; TOTAL PARENTERAL NUTRITION; UMBILICAL ARTERY; UMBILICAL VEIN; UNCONSCIOUSNESS;

DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTE TRANSFUSION; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MALE; OVERDOSE; OXYGEN INHALATION THERAPY; REFERENCE VALUES; THIOPENTAL; UNCONSCIOUSNESS;

EID: 69749119542     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2009.01394.x     Document Type: Article

References (10)

1. Duncan HP, Zurick NJ, Wolf AR. Should we reconsider awake neonatal intubation? A review of the evidence and treatment strategies. Paediatr Anaesth 2001 11 : 135 145.
2. Anand KJ, Johnston CC, Oberlander TF, Taddio A, Lehr VT, Walco GA. Analgesia and local anesthesia during invasive procedures in the neonate. Clin Ther 2005 27 : 844 876.
3. Byrne E, MacKinnon R. Should premedication be used for semi-urgent or elective intubation in neonates? Arch Dis Child 2006 91 : 79 83.
4. Hudson RJ, Stanski DR, Burch PG. Pharmacokinetics of methohexital and thiopental in surgical patients. Anesthesiology 1983 59 : 215 219.
5. Bhutada A, Sahni R, Rastogi S, Wung JT. Randomised controlled trial of thiopental for intubation in neonates. Arch Dis Child Fetal Neonatal Ed 2000 82 : F34 7.
6. Eyre JA, Wilkinson AR. Thiopentone induced coma after severe birth asphyxia. Arch Dis Child 1986 61 : 1084 1089.
7. Turner BK, Wakim JH, Secrest J, Zachary R. Neuroprotective effects of thiopental, propofol, and etomidate. AANA J 2005 73 : 297 302.
8. Taylor JA, Loan LA, Kamara J, Blackburn S, Whitney D. Medication administration variances before and after implementation of computerized physician order entry in a neonatal intensive care unit. Pediatrics 2008 121 : 123 128.
9. van den Anker JN. Managing drugs safely. Semin Fetal Neonatal Med 2005 10 : 73 81.
10. Kunac DL, Reith DM. Identification of priorities for medication safety in neonatal intensive care. Drug Saf 2005 28 : 251 261.