Anti-endothelial serum antibodies in a patient with Susac's syndrome

Journal of the Neurological Sciences

Volumn 285, Issue 1-2, 2009, Pages 259-261

  Jarius, S ^a   Neumayer, B ^a   Wandinger, K P ^b,c   Hartmann, M ^a   Wildemann, B ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c Institute of Experimental Immunology   (Germany)

Author keywords

Anti endothelial cell antibodies; Encephalopathy; Hearing loss; Retinal infarcts; Susac syndrome; Susac's syndrome

Indexed keywords

ENDOTHELIAL CELL ANTIBODY; IMMUNOGLOBULIN G; METHYLPREDNISOLONE;

ADULT; ANAMNESIS; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; BRAIN STEM; CASE REPORT; CEREBELLUM; CEREBROSPINAL FLUID ANALYSIS; CLINICAL EXAMINATION; CLINICAL FEATURE; DIFFUSION WEIGHTED IMAGING; DOPPLER FLOWMETRY; DRUG MEGADOSE; EYE EXAMINATION; FEMALE; HUMAN; HUMORAL IMMUNITY; IMMUNOFLUORESCENCE TEST; PRIORITY JOURNAL; SUSAC SYNDROME; TRANSESOPHAGEAL ECHOCARDIOGRAPHY;

ANIMALS; AUTOANTIBODIES; BRAIN; EAR, INNER; ENDOTHELIUM; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOCORTICOIDS; HUMANS; IMMUNOGLOBULIN G; INTRACRANIAL ARTERIAL DISEASES; LABYRINTH DISEASES; MAGNETIC RESONANCE IMAGING; MICE; MIDDLE AGED; RETINAL DISEASES; SYNDROME; TREATMENT OUTCOME;

EID: 69749116490     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.07.002     Document Type: Article

References (16)

1. Susac J.O., Hardman J.M., and Selhorst J.B. Microangiopathy of the brain and retina. Neurology 29 (1979) 313-316
2. Susac J.O. Susac's syndrome. AJNR Am J Neuroradiol 25 (2004) 351-352
3. Rennebohm R.M., and Susac J.O. Treatment of Susac's syndrome. J Neurol Sci 257 (2007) 215-220
4. Susac J.O., Egan R.A., Rennebohm R.M., and Lubow M. Susac's syndrome: 1975-2005 microangiopathy/autoimmune endotheliopathy. J Neurol Sci 257 (2007) 270-272
5. Jarius S., Franciotta D., Bergamaschi R., Wright H., Littleton E., Palace J., et al. NMO-IgG in the diagnosis of neuromyelitis optica. Neurology 68 (2007) 1076-1077
6. Waters P., Jarius S., Littleton E., Leite M.I., Jacob S., Gray B., et al. Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis. Arch Neurol 65 (2008) 913-919
7. Lennon V.A., Wingerchuk D.M., Kryzer T.J., Pittock S.J., Lucchinetti C.F., Fujihara K., et al. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 364 (2004) 2106-2112
8. Fox R.J., Costello F., Judkins A.R., Galetta S.L., Maguire A.M., Leonard B., et al. Treatment of Susac syndrome with gamma globulin and corticosteroids. J Neurol Sci 251 (2006) 17-22
9. Hahn J.S., Lannin W.C., and Sarwal M.M. Microangiopathy of brain, retina, and inner ear (Susac's syndrome) in an adolescent female presenting as acute disseminated encephalomyelitis. Pediatrics 114 (2004) 276-281
10. Vila N., Graus F., Blesa R., Santamaria J., Ribalta T., and Tolosa E. Microangiopathy of the brain and retina (Susac's syndrome): two patients with atypical features. Neurology 45 (1995) 1225-1226
11. Lee M.B., and Amezcua L. Rituximab for the stabilization of Susac syndrome: a case report. Neurology 72 (2009) A203
12. Belizna C., Duijvestijn A., Hamidou M., and Cohen Tervaert J.W. Antiendothelial cell antibodies in vasculitis and connective tissue disease. Ann Rheum Dis 65 (2006) 1545-1550
13. Tripathy N.K., Upadhyaya S., Sinha N., and Nityanand S. Complement and cell mediated cytotoxicity by antiendothelial cell antibodies in Takayasu's arteritis. J Rheumatol 28 (2001) 805-808
14. Hinson S.R., Pittock S.J., Lucchinetti C.F., Roemer S.F., Fryer J.P., Kryzer T.J., et al. Pathogenic potential of IgG binding to water channel extracellular domain in neuromyelitis optica. Neurology 69 (2007) 2221-2231
15. Jarius S., Paul F., Franciotta D., Waters P., Zipp F., Hohlfeld R., et al. Mechanisms of disease: aquaporin-4 antibodies in neuromyelitis optica. Nat Clin Pract Neurol 4 (2008) 202-214
16. Jarius S., Aboul-Enein F., Waters P., Kuenz B., Hauser A., Berger T., et al. Antibody to aquaporin-4 in the long-term course of neuromyelitis optica. Brain 131 (2008) 3072-3080