메뉴 건너뛰기




Volumn 2, Issue 3, 2007, Pages 315-331

The role of multiscale computational approaches for rational design of conventional and nanoparticle oral drug delivery systems

Author keywords

Computational chemistry; Computational modelling; Continuum; Multiscale; Oral drug delivery; Stochastic

Indexed keywords

ACRYLIC ACID COPOLYMER; AMINOSALICYLIC ACID DERIVATIVE; MESALAZINE; NANOPARTICLE; NANOSHELL; POLYMER; QUANTUM DOT;

EID: 69749115146     PISSN: 11769114     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (51)

References (103)
  • 1
    • 0035478779 scopus 로고    scopus 로고
    • Agoram B, Woltosz WS, Bolger BB. 2002. Predicting the impact of physiological and biochemical processes on oral drug bioavailability. Adv Drug Deliver Rev, 50.
    • Agoram B, Woltosz WS, Bolger BB. 2002. Predicting the impact of physiological and biochemical processes on oral drug bioavailability. Adv Drug Deliver Rev, 50.
  • 2
    • 0242403302 scopus 로고    scopus 로고
    • Finite Element Analysis of Transient Contaminant Transport: A Stochastic Approach
    • Aguirre CG, Haghighi K. 2002. Finite Element Analysis of Transient Contaminant Transport: A Stochastic Approach. T ASAE, 45:2049-59.
    • (2002) T ASAE , vol.45 , pp. 2049-2059
    • Aguirre, C.G.1    Haghighi, K.2
  • 4
    • 0036678994 scopus 로고    scopus 로고
    • 20/20 Vision: A brave new world of drug development
    • August
    • Anderson RJ. 2002.20/20 Vision: A brave new world of drug development. Curr Drug Discov, August: 25-9.
    • (2002) Curr Drug Discov , pp. 25-29
    • Anderson, R.J.1
  • 5
    • 0042964833 scopus 로고    scopus 로고
    • The meshless local petrov-galerkin (MLPG) method: A simple and less-costly alternative to the Finite Element and Boundary Element methods
    • Atluri SN, Shen S. 2002. The meshless local petrov-galerkin (MLPG) method: A simple and less-costly alternative to the Finite Element and Boundary Element methods. Comput Modeling Eng Sci, 3:11-52.
    • (2002) Comput Modeling Eng Sci , vol.3 , pp. 11-52
    • Atluri, S.N.1    Shen, S.2
  • 6
    • 0033715966 scopus 로고    scopus 로고
    • Molecular modeling of polyamidoamine (PAMAM) Starburst(TM) dendrimers
    • Bhalgat MK, Roberts JC. 2000. Molecular modeling of polyamidoamine (PAMAM) Starburst(TM) dendrimers. Eur Polym J, 36:647-51.
    • (2000) Eur Polym J , vol.36 , pp. 647-651
    • Bhalgat, M.K.1    Roberts, J.C.2
  • 7
    • 0036891062 scopus 로고    scopus 로고
    • In silico prediction of ADME and pharmacokinetics: Report of an expert meeting organised by COST B15
    • Boobis A, Gundert-Remy U, Kremers P, et al. 2002. In silico prediction of ADME and pharmacokinetics: Report of an expert meeting organised by COST B15. Eur J Pharm Sci, 17:183-93.
    • (2002) Eur J Pharm Sci , vol.17 , pp. 183-193
    • Boobis, A.1    Gundert-Remy, U.2    Kremers, P.3
  • 8
    • 0034849857 scopus 로고    scopus 로고
    • Multiscale modeling and simulation methods with applications to dendritic polymers
    • S :345-56
    • Cagin T, Wang G, Martin R, et al. 2001. Multiscale modeling and simulation methods with applications to dendritic polymers. Comput Theor Polym, S 11:345-56.
    • (2001) Comput Theor Polym , pp. 11
    • Cagin, T.1    Wang, G.2    Martin, R.3
  • 9
    • 33745929638 scopus 로고    scopus 로고
    • A generalized space-time mathematical homogenization theory for bridging atomistic and continuum scales
    • Chen W, Fish J. 2006. A generalized space-time mathematical homogenization theory for bridging atomistic and continuum scales. International Journal for Numerical Methods in Engineering, 67:253-71.
    • (2006) International Journal for Numerical Methods in Engineering , vol.67 , pp. 253-271
    • Chen, W.1    Fish, J.2
  • 10
    • 1342263874 scopus 로고    scopus 로고
    • Original structure-property relationships derived from a new modeling of diffusion of pure solvents through polymer membranes
    • Clement R, Jonquieres A, Sarti I, et al. 2004. Original structure-property relationships derived from a new modeling of diffusion of pure solvents through polymer membranes. J Membrane Sci, 232:141-52.
    • (2004) J Membrane Sci , vol.232 , pp. 141-152
    • Clement, R.1    Jonquieres, A.2    Sarti, I.3
  • 11
    • 0035073301 scopus 로고    scopus 로고
    • Modeling and comparison of dissolution profiles
    • Costa P, Sousa L, Jose M. 2001. Modeling and comparison of dissolution profiles. Eur J Pharm Sci, 13:123-33.
    • (2001) Eur J Pharm Sci , vol.13 , pp. 123-133
    • Costa, P.1    Sousa, L.2    Jose, M.3
  • 12
    • 2942735394 scopus 로고    scopus 로고
    • Transport of polymeric nanoparticle gene carriers in gastric mucus
    • Dawson M, Krauland E, Wirtz D, et al. 2004. Transport of polymeric nanoparticle gene carriers in gastric mucus. Biotechnology Progress, 20:851-7.
    • (2004) Biotechnology Progress , vol.20 , pp. 851-857
    • Dawson, M.1    Krauland, E.2    Wirtz, D.3
  • 13
    • 84873100537 scopus 로고    scopus 로고
    • Donea J, Huerta A, Ponthot J-P, et al 2004. Arbitrary lagrangian-eulerian methods (Chapter 14). In Encyclopedia of Computational Mechanics, 1: Fundamentals., ed. E Stein, dB R., H T.J.R. New York: John Wiley & Sons, Ltd.
    • Donea J, Huerta A, Ponthot J-P, et al 2004. Arbitrary lagrangian-eulerian methods (Chapter 14). In Encyclopedia of Computational Mechanics, Volume 1: Fundamentals., ed. E Stein, dB R., H T.J.R. New York: John Wiley & Sons, Ltd.
  • 14
    • 0345404110 scopus 로고    scopus 로고
    • Preparation and properties of magnetite and polymer magnetite nanoparticles
    • Dresco PA, Zaitsev VS, Gambino RJ, et al. 1999. Preparation and properties of magnetite and polymer magnetite nanoparticles. Langmuir, 15:1945-51.
    • (1999) Langmuir , vol.15 , pp. 1945-1951
    • Dresco, P.A.1    Zaitsev, V.S.2    Gambino, R.J.3
  • 15
    • 1642538159 scopus 로고    scopus 로고
    • Interactions of hyaluronan-targeted liposomes with cultured cells: Modeling of binding and Endocytosis. Methods in Enzymology
    • ed. N Duzgunes, pp, Academic Press
    • Eliaz RE, Nir S, Szoka J, Francis C. 2004. Interactions of hyaluronan-targeted liposomes with cultured cells: modeling of binding and Endocytosis. Methods in Enzymology. In Liposomes, Part D, ed. N Duzgunes, pp. 16-33: Academic Press.
    • (2004) Liposomes, Part D , pp. 16-33
    • Eliaz, R.E.1    Nir, S.2    Szoka, J.3    Francis, C.4
  • 16
    • 33646582037 scopus 로고    scopus 로고
    • Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
    • Farokhzad OC, Cheng J, Teply BA, et al. 2006. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. PNAS, 103:6315-20.
    • (2006) PNAS , vol.103 , pp. 6315-6320
    • Farokhzad, O.C.1    Cheng, J.2    Teply, B.A.3
  • 17
    • 24644502180 scopus 로고    scopus 로고
    • Microfluidic system for studying the interaction of nanoparticles and microparticles with cells
    • Farokhzad OC, Khademhosseini A, Jon S, et al. 2005. Microfluidic system for studying the interaction of nanoparticles and microparticles with cells. Anal Chem, 77:5453-9.
    • (2005) Anal Chem , vol.77 , pp. 5453-5459
    • Farokhzad, O.C.1    Khademhosseini, A.2    Jon, S.3
  • 18
    • 1542426445 scopus 로고    scopus 로고
    • A moving overset grid method for interface dynamics applied to non-newtonian hele-shaw flow
    • Fast P, Shelley MJ. 2004. A moving overset grid method for interface dynamics applied to non-newtonian hele-shaw flow. J Comput Phys, 195:117-42.
    • (2004) J Comput Phys , vol.195 , pp. 117-142
    • Fast, P.1    Shelley, M.J.2
  • 19
    • 1842635971 scopus 로고    scopus 로고
    • Discrete-to-continuum bridging based on multigrid principles
    • Fish J, Chen W. 2004a. Discrete-to-continuum bridging based on multigrid principles. Comput Method Appl M, 193:1693-711.
    • (2004) Comput Method Appl M , vol.193 , pp. 1693-1711
    • Fish, J.1    Chen, W.2
  • 23
    • 4544247978 scopus 로고    scopus 로고
    • The role of binder mobility in spontaneous adhesive contact and implications for cell adhesion
    • Freund LB, Lin Y. 2004. The role of binder mobility in spontaneous adhesive contact and implications for cell adhesion. J Mech Phys Solids, 52:2455-72.
    • (2004) J Mech Phys Solids , vol.52 , pp. 2455-2472
    • Freund, L.B.1    Lin, Y.2
  • 24
    • 22144477899 scopus 로고    scopus 로고
    • Mechanics of receptor-mediated endocytosis
    • Gao H, Shi W, Freund LB. 2005. Mechanics of receptor-mediated endocytosis. P Natl Acad Sci, 102:9469-74.
    • (2005) P Natl Acad Sci , vol.102 , pp. 9469-9474
    • Gao, H.1    Shi, W.2    Freund, L.B.3
  • 25
    • 0021520019 scopus 로고
    • Receptor-mediated endocytosis: A model and its implications for experimental analysis
    • Gex-Fabry M, DeLisi C. 1984. Receptor-mediated endocytosis: a model and its implications for experimental analysis. Am J Physiol, 247:R768-R79.
    • (1984) Am J Physiol , vol.247
    • Gex-Fabry, M.1    DeLisi, C.2
  • 27
    • 0041848500 scopus 로고    scopus 로고
    • Ghoniem NM, Cho K. 2002. The emerging role of multiscale modeling in nano- and micro-Mechanics of materials. Comput Modeling Eng Sci, 3.
    • Ghoniem NM, Cho K. 2002. The emerging role of multiscale modeling in nano- and micro-Mechanics of materials. Comput Modeling Eng Sci, 3.
  • 28
    • 0035986794 scopus 로고    scopus 로고
    • Application of Topological Descriptors in QSAR and Drug Design: History and New Trends
    • Gozalbes R, Doucet JP, Derouin F. 2002. Application of Topological Descriptors in QSAR and Drug Design: History and New Trends. Curr Drug Targets: Infect Disord, 2:93-102.
    • (2002) Curr Drug Targets: Infect Disord , vol.2 , pp. 93-102
    • Gozalbes, R.1    Doucet, J.P.2    Derouin, F.3
  • 29
    • 30444434228 scopus 로고    scopus 로고
    • Grasela T, Fiedler-Kelly J, Walawander C, Owen J, Cirincione B, et al. 2005. Challenges in the Transition to Model-Based Development. AAPS J, 07:E488-E95.
    • Grasela T, Fiedler-Kelly J, Walawander C, Owen J, Cirincione B, et al. 2005. Challenges in the Transition to Model-Based Development. AAPS J, 07:E488-E95.
  • 30
    • 0031026707 scopus 로고    scopus 로고
    • Simulation models to predict oral drug absorption from in vitro data
    • Grass GM. 1997. Simulation models to predict oral drug absorption from in vitro data. Adv Drug Deliver Rev, 23:199-219.
    • (1997) Adv Drug Deliver Rev , vol.23 , pp. 199-219
    • Grass, G.M.1
  • 31
    • 0037204541 scopus 로고    scopus 로고
    • Computer systems for the prediction of toxicity: An update
    • Greene N. 2002. Computer systems for the prediction of toxicity: an update. Adv Drug Deliver Rev, 54:417-31.
    • (2002) Adv Drug Deliver Rev , vol.54 , pp. 417-431
    • Greene, N.1
  • 32
    • 23444444512 scopus 로고
    • Biodegradable Long-Circulating Polymeric Nanospheres
    • Gref R, Minamitake Y, Peracchia MT, et al. 1994. Biodegradable Long-Circulating Polymeric Nanospheres. Science, 263:1600-3.
    • (1994) Science , vol.263 , pp. 1600-1603
    • Gref, R.1    Minamitake, Y.2    Peracchia, M.T.3
  • 33
    • 0346207426 scopus 로고    scopus 로고
    • Volume-of-fluid interface tracking with smoothed surface stress methods for three-dimensional flows
    • Gueyffier D, Li J, Nadim A, et al. 1999. Volume-of-fluid interface tracking with smoothed surface stress methods for three-dimensional flows. J Comput Phys, 152:423-56.
    • (1999) J Comput Phys , vol.152 , pp. 423-456
    • Gueyffier, D.1    Li, J.2    Nadim, A.3
  • 34
    • 84873100539 scopus 로고    scopus 로고
    • Biological variability and targeted delivery of therapeutics for Inflammatory Bowel Diseases: An in silico approach
    • Submitted
    • Haddish-Berhane N, Farhadi A, Nyquist C, et al. 2006a. Biological variability and targeted delivery of therapeutics for Inflammatory Bowel Diseases: an in silico approach. Inflammation & Allergy - Drug Targets, Submitted.
    • (2006) Inflammation & Allergy - Drug Targets
    • Haddish-Berhane, N.1    Farhadi, A.2    Nyquist, C.3
  • 35
    • 29244434124 scopus 로고    scopus 로고
    • A multi-scale stochastic drug release model for polymer-coated targeted drug delivery systems
    • Haddish-Berhane N, Nyquist C, Haghighi K, et al. 2006b. A multi-scale stochastic drug release model for polymer-coated targeted drug delivery systems. J Control Release, 110:314-22.
    • (2006) J Control Release , vol.110 , pp. 314-322
    • Haddish-Berhane, N.1    Nyquist, C.2    Haghighi, K.3
  • 36
    • 0019367877 scopus 로고
    • Volume of fluid (VOF) method for the dynamics of free boundaries
    • Hirt CW, Nichols BD. 1981. Volume of fluid (VOF) method for the dynamics of free boundaries. J Comput Phys, 39:201-25.
    • (1981) J Comput Phys , vol.39 , pp. 201-225
    • Hirt, C.W.1    Nichols, B.D.2
  • 38
    • 14744279591 scopus 로고    scopus 로고
    • Modeling of drug release from polymeric delivery systems - a review
    • Kanjickal DG, Lopina ST. 2004. Modeling of drug release from polymeric delivery systems - a review. Crit Rev Ther Drug, 21:245-386.
    • (2004) Crit Rev Ther Drug , vol.21 , pp. 245-386
    • Kanjickal, D.G.1    Lopina, S.T.2
  • 40
    • 0001728908 scopus 로고    scopus 로고
    • Quantum-Chemical Descriptors in QSAR/QSPR Studies
    • Karelson M, Lobanov VS, Katritzky AR. 1996. Quantum-Chemical Descriptors in QSAR/QSPR Studies. Chem Rev, 96:1027-44.
    • (1996) Chem Rev , vol.96 , pp. 1027-1044
    • Karelson, M.1    Lobanov, V.S.2    Katritzky, A.R.3
  • 41
    • 0033474376 scopus 로고    scopus 로고
    • QSPR and QSAR models derived using large molecular descriptor spaces. A review of CODESSA applications
    • Karelson M, Maran U, Wang Y, et al. 1999. QSPR and QSAR models derived using large molecular descriptor spaces. A review of CODESSA applications. Collect Czech Chem Commun, 64:1551-71.
    • (1999) Collect Czech Chem Commun , vol.64 , pp. 1551-1571
    • Karelson, M.1    Maran, U.2    Wang, Y.3
  • 42
    • 0000734338 scopus 로고    scopus 로고
    • Katritzky AR, Ignatchenko ES, Barcock RA, et al. 1994. Prediction of gas chromatographic retention times and response factors using a general qualitative structure-property relationships Treatment. Anal Chem, 1799-1807.
    • Katritzky AR, Ignatchenko ES, Barcock RA, et al. 1994. Prediction of gas chromatographic retention times and response factors using a general qualitative structure-property relationships Treatment. Anal Chem, 1799-1807.
  • 43
    • 0001700161 scopus 로고    scopus 로고
    • Prediction of melting points for the substituted benzenes: A QSPR Approach
    • Katritzky AR, Maran U, Karelson M, et al. 1997. Prediction of melting points for the substituted benzenes: A QSPR Approach. J Chem Inf Comput Sci, 37:913-9.
    • (1997) J Chem Inf Comput Sci , vol.37 , pp. 913-919
    • Katritzky, A.R.1    Maran, U.2    Karelson, M.3
  • 44
    • 0001379475 scopus 로고    scopus 로고
    • Prediction of Polymer Glass Transition Temperatures Using a General Quantitative Structure-Property Relationship Treatment
    • Katritzky AR, Rachwal P, Law KW, et al. 1996. Prediction of Polymer Glass Transition Temperatures Using a General Quantitative Structure-Property Relationship Treatment. J Chem Inf Comput Sci, 36:879-84.
    • (1996) J Chem Inf Comput Sci , vol.36 , pp. 879-884
    • Katritzky, A.R.1    Rachwal, P.2    Law, K.W.3
  • 45
    • 33646245291 scopus 로고    scopus 로고
    • Nanotechnology, nanomedicine, and the development of new, effective therapies for cancer
    • Kawasaki ES, Player A. 2005. Nanotechnology, nanomedicine, and the development of new, effective therapies for cancer. Nanomedicine, 1:101-9.
    • (2005) Nanomedicine , vol.1 , pp. 101-109
    • Kawasaki, E.S.1    Player, A.2
  • 46
    • 0030886937 scopus 로고    scopus 로고
    • Managing the drug discovery/development interface
    • Kennedy T. 1997. Managing the drug discovery/development interface. Drug Discovery Today, 2:436-44.
    • (1997) Drug Discovery Today , vol.2 , pp. 436-444
    • Kennedy, T.1
  • 47
    • 9644254309 scopus 로고    scopus 로고
    • Epithelial internalization of superparamagnetic nanoparticles and response to external magnetic field
    • Kenneth D, Charles S, Kevin L, et al. 2005. Epithelial internalization of superparamagnetic nanoparticles and response to external magnetic field. Biomaterials, 26:2061-72.
    • (2005) Biomaterials , vol.26 , pp. 2061-2072
    • Kenneth, D.1    Charles, S.2    Kevin, L.3
  • 48
    • 24944565527 scopus 로고    scopus 로고
    • Controllable Self-Assembly of Nanoparticles for Specific Delivery of Multiple Therapeutic Molecules to Cancer Cells Using RNA Nanotechnology
    • Khaled A, Guo S, Li F, et al. 2005. Controllable Self-Assembly of Nanoparticles for Specific Delivery of Multiple Therapeutic Molecules to Cancer Cells Using RNA Nanotechnology. Nano Letters, 5:1797-808.
    • (2005) Nano Letters , vol.5 , pp. 1797-1808
    • Khaled, A.1    Guo, S.2    Li, F.3
  • 49
    • 28744441403 scopus 로고    scopus 로고
    • Transepithelial and endothelial transport of poly (amidoamine) dendrimers
    • Kitchens KM, El-Sayed MEH, Ghandehari H. 2005. Transepithelial and endothelial transport of poly (amidoamine) dendrimers. Adv Drug Deliver Rev, 57:2163-76.
    • (2005) Adv Drug Deliver Rev , vol.57 , pp. 2163-2176
    • Kitchens, K.M.1    El-Sayed, M.E.H.2    Ghandehari, H.3
  • 51
    • 84873100554 scopus 로고    scopus 로고
    • Kubinyi H. 2004. Validation and predictivity of QSAR models. Presented at 15th EURO-QSAR Symposium, Istanbul, Turkey.
    • Kubinyi H. 2004. Validation and predictivity of QSAR models. Presented at 15th EURO-QSAR Symposium, Istanbul, Turkey.
  • 52
    • 0020936133 scopus 로고
    • Chemical and physical structure of polymers as carriers for controlled release of bioactive agents: A review
    • Langer R, Peppas NA. 1983. Chemical and physical structure of polymers as carriers for controlled release of bioactive agents: a review. J Macromol Sci Rev Macromol Chem Phys, C23:61-126.
    • (1983) J Macromol Sci Rev Macromol Chem Phys , vol.C23 , pp. 61-126
    • Langer, R.1    Peppas, N.A.2
  • 55
    • 33644822413 scopus 로고    scopus 로고
    • Viral nanoparticles as tools for intravital vascular imaging
    • Lewis JD, Destito G, Zijlstra A, et al. 2006. Viral nanoparticles as tools for intravital vascular imaging. Nature Medicine, 12:354-06.
    • (2006) Nature Medicine , vol.12 , pp. 354-306
    • Lewis, J.D.1    Destito, G.2    Zijlstra, A.3
  • 56
    • 19144370524 scopus 로고    scopus 로고
    • An arbitrary lagrangian eulerian method for moving-boundary problems and its application to jumping over water
    • Li J, Hesse M, Ziegler J, et al. 2005. An arbitrary lagrangian eulerian method for moving-boundary problems and its application to jumping over water. J Comput Phys, 208:289-314.
    • (2005) J Comput Phys , vol.208 , pp. 289-314
    • Li, J.1    Hesse, M.2    Ziegler, J.3
  • 57
    • 0035789518 scopus 로고    scopus 로고
    • GROMACS 3.0: A package for molecular simulation and trajectory analysis
    • Lindahl EBH, van der Spoel D. 2001. GROMACS 3.0: a package for molecular simulation and trajectory analysis. J Mol Model, 7:306-17.
    • (2001) J Mol Model , vol.7 , pp. 306-317
    • Lindahl, E.B.H.1    van der Spoel, D.2
  • 58
    • 29144467865 scopus 로고    scopus 로고
    • Mesoscale modelling: Recent developments and applications to nanocomposites, drug delivery and precipitation membranes
    • Maiti A, Wescott J, Goldbeck-Wood G. 2004. Mesoscale modelling: recent developments and applications to nanocomposites, drug delivery and precipitation membranes. Int J Nanotechnology, 2:198-214.
    • (2004) Int J Nanotechnology , vol.2 , pp. 198-214
    • Maiti, A.1    Wescott, J.2    Goldbeck-Wood, G.3
  • 59
    • 24944496710 scopus 로고    scopus 로고
    • Pharmacokinetics, tissue distribution and bioavailability of clozapine solid lipid nanoparticles after intravenous and intraduedenal administration
    • Manjunath K, Venkateswarlu V. 2005. Pharmacokinetics, tissue distribution and bioavailability of clozapine solid lipid nanoparticles after intravenous and intraduedenal administration. Journal of Controlled Release, 107:215-28.
    • (2005) Journal of Controlled Release , vol.107 , pp. 215-228
    • Manjunath, K.1    Venkateswarlu, V.2
  • 60
    • 0027906125 scopus 로고
    • Monte carlo studies of dendrimer macromolecules
    • Mansfield ML, Klushin LI. 1993. Monte carlo studies of dendrimer macromolecules. Macromolecules, 26:4262-8.
    • (1993) Macromolecules , vol.26 , pp. 4262-4268
    • Mansfield, M.L.1    Klushin, L.I.2
  • 61
    • 0002823628 scopus 로고    scopus 로고
    • Direct simulations of 2D fluid-particle flows in biperiodic domains
    • Maury B. 1999. Direct simulations of 2D fluid-particle flows in biperiodic domains. J Comput Phys, 156:325-51.
    • (1999) J Comput Phys , vol.156 , pp. 325-351
    • Maury, B.1
  • 62
    • 30644466989 scopus 로고    scopus 로고
    • Polymeric nanoparticle preparation that eradicates tumors
    • McCarthy JR, Perez JM, Bruckner C, et al. 2005. Polymeric nanoparticle preparation that eradicates tumors. Nano Letters, 5:2552-6.
    • (2005) Nano Letters , vol.5 , pp. 2552-2556
    • McCarthy, J.R.1    Perez, J.M.2    Bruckner, C.3
  • 64
    • 0002083175 scopus 로고
    • Optimal feeding strategy for identification of monod-type models by fed-batch experiments
    • ed. NM Fish, RI Fox, NF Thomhill, pp, Amsterdam: Elsevier
    • Munack A. 1989. Optimal feeding strategy for identification of monod-type models by fed-batch experiments. In Computer applications in fermentation technology, modelling and control of biotechnological process, ed. NM Fish, RI Fox, NF Thomhill, pp. 195-204. Amsterdam: Elsevier.
    • (1989) Computer applications in fermentation technology, modelling and control of biotechnological process , pp. 195-204
    • Munack, A.1
  • 65
    • 0001177516 scopus 로고    scopus 로고
    • Optimal experimental design for the parameter estimation of conduction heated foods
    • Nahor HB, Scheerlinck N, Verniest R, et al. 2001. Optimal experimental design for the parameter estimation of conduction heated foods. Journal of Food Engineering, 48:109-19.
    • (2001) Journal of Food Engineering , vol.48 , pp. 109-119
    • Nahor, H.B.1    Scheerlinck, N.2    Verniest, R.3
  • 66
    • 33845184343 scopus 로고
    • Starburst dendrimers. Part V: Molecular shape control
    • Naylor AM, Goddard III WA, Kiefer GE, et al. 1989. Starburst dendrimers. Part V: Molecular shape control. J Am Chem Soc, 111:2339-41.
    • (1989) J Am Chem Soc , vol.111 , pp. 2339-2341
    • Naylor, A.M.1    Goddard III, W.A.2    Kiefer, G.E.3
  • 67
    • 1142285267 scopus 로고    scopus 로고
    • Computational modeling of the sugar-lectin interaction
    • Neumann D, Lehr C-M, Lenhof H-P, et al. 2004. Computational modeling of the sugar-lectin interaction. Adv Drug Deliver Rev, 56:437-57.
    • (2004) Adv Drug Deliver Rev , vol.56 , pp. 437-457
    • Neumann, D.1    Lehr, C.-M.2    Lenhof, H.-P.3
  • 68
    • 0031464981 scopus 로고    scopus 로고
    • Finite element perturbation analysis of non-linear heat coduction with random field parameters
    • Nicolai BM, Baerdemaeker JD. 1997. Finite element perturbation analysis of non-linear heat coduction with random field parameters. Int J Numer Method H, 7:525-44.
    • (1997) Int J Numer Method H , vol.7 , pp. 525-544
    • Nicolai, B.M.1    Baerdemaeker, J.D.2
  • 69
    • 0345621597 scopus 로고    scopus 로고
    • A variance propagation algorithm for the computation of heat conduction under stochastic conditions
    • Nicolai BM, Baerdemaeker JD. 1999. A variance propagation algorithm for the computation of heat conduction under stochastic conditions. Int J Heat Mass Transfer, 42:1513-20.
    • (1999) Int J Heat Mass Transfer , vol.42 , pp. 1513-1520
    • Nicolai, B.M.1    Baerdemaeker, J.D.2
  • 70
    • 23844491922 scopus 로고    scopus 로고
    • An arbitrary lagrangian eulerian (ALE) formulation for free surface flows using the characterstic-based split (CBS) scheme
    • Nithiarasu P. 2005. An arbitrary lagrangian eulerian (ALE) formulation for free surface flows using the characterstic-based split (CBS) scheme. Int J Numer Meth Fl, 48:1415-28.
    • (2005) Int J Numer Meth Fl , vol.48 , pp. 1415-1428
    • Nithiarasu, P.1
  • 71
    • 0033579938 scopus 로고    scopus 로고
    • Interactions of influenza virus with cultured cells: Detailed kinetic modeling of binding and endocytosis
    • Nunes-Correia I, Ramalho-Santos J, Nir S, et al. 1999. Interactions of influenza virus with cultured cells: Detailed kinetic modeling of binding and endocytosis. Biochemistry, 38:1095-101.
    • (1999) Biochemistry , vol.38 , pp. 1095-1101
    • Nunes-Correia, I.1    Ramalho-Santos, J.2    Nir, S.3
  • 72
    • 33845214358 scopus 로고    scopus 로고
    • Principles for characterizing the potential human health effects from exposure to nanomaterials: Elements of a screening strategy
    • Oberdorster G, Maynard A, Donaldson K, et al. 2005. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Particle and Fibre Toxicology, 2:1-35.
    • (2005) Particle and Fibre Toxicology , vol.2 , pp. 1-35
    • Oberdorster, G.1    Maynard, A.2    Donaldson, K.3
  • 73
    • 25444513974 scopus 로고    scopus 로고
    • A nanoparticle-based model delivery system to guide the rational design of gene delivery to the Liver 2. In Vitro and In Vivo Uptake Results
    • Popielarski SR, Hu-Lieskovan S, French SW, et al. 2005. A nanoparticle-based model delivery system to guide the rational design of gene delivery to the Liver 2. In Vitro and In Vivo Uptake Results. Bioconjugate Chem, 16:1071-80.
    • (2005) Bioconjugate Chem , vol.16 , pp. 1071-1080
    • Popielarski, S.R.1    Hu-Lieskovan, S.2    French, S.W.3
  • 74
    • 0033618513 scopus 로고    scopus 로고
    • A front-tracking algorithm for accurate representation of surface tension
    • Popinet S, Zaleski S. 1999. A front-tracking algorithm for accurate representation of surface tension. Int J Numer Meth Fl, 30:775-93.
    • (1999) Int J Numer Meth Fl , vol.30 , pp. 775-793
    • Popinet, S.1    Zaleski, S.2
  • 75
    • 21844437958 scopus 로고    scopus 로고
    • Biosensor-Controlled Gene Therapy/ Drug Delivery with Nanoparticles for Nanomedicine
    • Prow TW, Rose WA, Wang N, et al. 2005. Biosensor-Controlled Gene Therapy/ Drug Delivery with Nanoparticles for Nanomedicine. Proc SPIE, 5692:199-208.
    • (2005) Proc SPIE , vol.5692 , pp. 199-208
    • Prow, T.W.1    Rose, W.A.2    Wang, N.3
  • 76
    • 0036744856 scopus 로고    scopus 로고
    • Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells Through the folate receptor
    • 19:1310-b
    • Quintana A, Raczka E, Piehler L, et al. 2002. Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells Through the folate receptor. Pharm Res, 19:1310-b.
    • (2002) Pharm Res
    • Quintana, A.1    Raczka, E.2    Piehler, L.3
  • 79
    • 19644371654 scopus 로고    scopus 로고
    • Reddy MR, Erion MD, A.A. 2000. Free energy calculations: Use and limitations in predicting ligand binding affinities. In Reviews in Computational Chemistry, pp. 217-304. New York: VCH Publishers.
    • Reddy MR, Erion MD, A.A. 2000. Free energy calculations: Use and limitations in predicting ligand binding affinities. In Reviews in Computational Chemistry, pp. 217-304. New York: VCH Publishers.
  • 80
    • 0037059250 scopus 로고    scopus 로고
    • PROST: A parabolic reconstruction of surface tension for the volume-of-fluid method
    • Renardy Y, Renardy M. 2002. PROST: A parabolic reconstruction of surface tension for the volume-of-fluid method. J Comput Phys, 183:400-21.
    • (2002) J Comput Phys , vol.183 , pp. 400-421
    • Renardy, Y.1    Renardy, M.2
  • 81
    • 0031787885 scopus 로고    scopus 로고
    • Coatings for controlled release drug delivery systems
    • Rhodes CT, Porter CS. 1998. Coatings for controlled release drug delivery systems. Drug Dev Ind Pharm, 24:1139-54.
    • (1998) Drug Dev Ind Pharm , vol.24 , pp. 1139-1154
    • Rhodes, C.T.1    Porter, C.S.2
  • 82
    • 22244460241 scopus 로고    scopus 로고
    • Direct fabrication and harvesting of monodisperse shape-specific nanobiomaterials
    • Rolland JP, Maynor BW, Euliss LE, et al. 2005. Direct fabrication and harvesting of monodisperse shape-specific nanobiomaterials. Journal of the American Chemical Society, 127:10096-100.
    • (2005) Journal of the American Chemical Society , vol.127 , pp. 10096-10100
    • Rolland, J.P.1    Maynor, B.W.2    Euliss, L.E.3
  • 83
    • 0032711921 scopus 로고    scopus 로고
    • Lectin-mediated transport of nanoparticles across Caco-2 and OK cells
    • Russell-Jones GJ, Veitch H, Arthur L. 1999. Lectin-mediated transport of nanoparticles across Caco-2 and OK cells. Int J Pharm, 190:165-74.
    • (1999) Int J Pharm , vol.190 , pp. 165-174
    • Russell-Jones, G.J.1    Veitch, H.2    Arthur, L.3
  • 84
    • 0021517185 scopus 로고
    • Numerical solution of free-boundary problems in fluid mechanics. Part 2: Buoyancy-driven motion of a gas bubble through a quiescent liquid
    • Ryskin G, Leal LG. 1984. Numerical solution of free-boundary problems in fluid mechanics. Part 2: Buoyancy-driven motion of a gas bubble through a quiescent liquid. J Fluid Mech, 148:19-36.
    • (1984) J Fluid Mech , vol.148 , pp. 19-36
    • Ryskin, G.1    Leal, L.G.2
  • 85
    • 1242314687 scopus 로고    scopus 로고
    • A quantitative structure-property relationship for predicting drug solubility in PEG 400/Water cosolvent systems
    • Rytting E, Lentz KA, Chen X-Q, et al. 2004. A quantitative structure-property relationship for predicting drug solubility in PEG 400/Water cosolvent systems. Pharm Res, 21:237-44.
    • (2004) Pharm Res , vol.21 , pp. 237-244
    • Rytting, E.1    Lentz, K.A.2    Chen, X.-Q.3
  • 86
    • 0033489545 scopus 로고    scopus 로고
    • Direct numerical simulation of free surface and interfacial flow
    • Scardovelli R, Zaleski S. 1999. Direct numerical simulation of free surface and interfacial flow. Ann Rev Fluid Mech, 31:567-604.
    • (1999) Ann Rev Fluid Mech , vol.31 , pp. 567-604
    • Scardovelli, R.1    Zaleski, S.2
  • 87
    • 0035796801 scopus 로고    scopus 로고
    • A variance propagation algorithm for stochastic heat and mass transfer problems in food processes
    • Scheerlinck N, Verboven P, Stigter JD, et al. 2001. A variance propagation algorithm for stochastic heat and mass transfer problems in food processes. Int J Numer Meth Eng, 51:961-83.
    • (2001) Int J Numer Meth Eng , vol.51 , pp. 961-983
    • Scheerlinck, N.1    Verboven, P.2    Stigter, J.D.3
  • 88
    • 7544226311 scopus 로고    scopus 로고
    • PRODRG: A tool for high-throughput crystallography of protein-ligand complexes
    • Schuttelkopf AW, van Aalten DMF. 2004. PRODRG: a tool for high-throughput crystallography of protein-ligand complexes. Acta Crystallogr D, 60:1355-63.
    • (2004) Acta Crystallogr D , vol.60 , pp. 1355-1363
    • Schuttelkopf, A.W.1    van Aalten, D.M.F.2
  • 90
    • 84873100517 scopus 로고    scopus 로고
    • Adaptive discretization and modeling
    • ed, Broomsfield, Colorado: Department of energy
    • Shephard MS. 2004. Adaptive discretization and modeling. In Final report: second DOE workshop on multiscale problems, ed. D Estep, JN Shadid, D Zachmann, pp. 52. Broomsfield, Colorado: Department of energy
    • (2004) Final report: Second DOE workshop on multiscale problems , pp. 52
    • Shephard, M.S.1
  • 91
    • 0024390310 scopus 로고
    • Kinetic study of internalization and degradation of I-labeled follicle-stimulating hormone in mouse Sertoli cells and its relevance to other systems
    • Shimizu A, Kawashima S. 1989. Kinetic study of internalization and degradation of I-labeled follicle-stimulating hormone in mouse Sertoli cells and its relevance to other systems. J Biol Chem, 264:13632-8.
    • (1989) J Biol Chem , vol.264 , pp. 13632-13638
    • Shimizu, A.1    Kawashima, S.2
  • 92
    • 0035844746 scopus 로고    scopus 로고
    • Mathematical modeling of bioerodible, polymeric drug delivery systems
    • Siepmann J, Gopferich A. 2001. Mathematical modeling of bioerodible, polymeric drug delivery systems. Adv Drug Deliver Rev, 48:229-47.
    • (2001) Adv Drug Deliver Rev , vol.48 , pp. 229-247
    • Siepmann, J.1    Gopferich, A.2
  • 93
    • 0035844738 scopus 로고    scopus 로고
    • Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC)
    • Siepmann J, Peppas NA. 2001. Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Adv Drug Deliver Rev, 48:139-57.
    • (2001) Adv Drug Deliver Rev , vol.48 , pp. 139-157
    • Siepmann, J.1    Peppas, N.A.2
  • 94
    • 25844495323 scopus 로고    scopus 로고
    • An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface PE-Gylation on in vivo biodistribution
    • Sun X, Rossin R, Turner JL, et al. 2005. An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface PE-Gylation on in vivo biodistribution. Biomacromolecules, 6:2541-54.
    • (2005) Biomacromolecules , vol.6 , pp. 2541-2554
    • Sun, X.1    Rossin, R.2    Turner, J.L.3
  • 95
    • 0029743319 scopus 로고    scopus 로고
    • Water-Soluble Knedel-like Structures: The preparation of shell-cross-linked small particles
    • Thurmond KBI, Kowalewski T, Wooley KL. 1996. Water-Soluble Knedel-like Structures: The preparation of shell-cross-linked small particles. J Am Chem Soc, 118:7239-40.
    • (1996) J Am Chem Soc , vol.118 , pp. 7239-7240
    • Thurmond, K.B.I.1    Kowalewski, T.2    Wooley, K.L.3
  • 96
    • 0000163297 scopus 로고
    • Computations of three-dimensional rayleigh-taylor instability
    • Tryggvason G, Unverdi SO. 1990. Computations of three-dimensional rayleigh-taylor instability. Phys Fluids A-Fluid, 2:656-9.
    • (1990) Phys Fluids A-Fluid , vol.2 , pp. 656-659
    • Tryggvason, G.1    Unverdi, S.O.2
  • 97
    • 2642584695 scopus 로고    scopus 로고
    • Analysis of compartmental models of ligand-induced endocytosis
    • Tzafriri AR, Wu D, Edelman ER. 2004. Analysis of compartmental models of ligand-induced endocytosis. J Theor Biol, 229:127-38.
    • (2004) J Theor Biol , vol.229 , pp. 127-138
    • Tzafriri, A.R.1    Wu, D.2    Edelman, E.R.3
  • 98
    • 3242694679 scopus 로고
    • A front-tracking method for viscous, incompressible, multi-fluid flows
    • Unverdi SO, Tryggvason G. 1992. A front-tracking method for viscous, incompressible, multi-fluid flows. J Comput Phys, 100:25-37.
    • (1992) J Comput Phys , vol.100 , pp. 25-37
    • Unverdi, S.O.1    Tryggvason, G.2
  • 99
    • 0037364162 scopus 로고    scopus 로고
    • ADMET in silico modeling: Towards prediction paradise?
    • van de Waterbeemd H, Gifford E. 2003. ADMET in silico modeling: Towards prediction paradise? Nat Rev Drug Discov, 2:192-204.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 192-204
    • van de Waterbeemd, H.1    Gifford, E.2
  • 100
    • 34548656569 scopus 로고    scopus 로고
    • Welcome to the international journey to improving human health
    • Webster TJ. 2006. Welcome to the international journey to improving human health. Int J Nanomedicine, 1:1-2.
    • (2006) Int J Nanomedicine , vol.1 , pp. 1-2
    • Webster, T.J.1
  • 101
    • 0019404817 scopus 로고
    • A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands
    • Wiley HS, Cunningham DD. 1981. A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands. Cell, 25:433-40.
    • (1981) Cell , vol.25 , pp. 433-440
    • Wiley, H.S.1    Cunningham, D.D.2
  • 102
    • 0019945866 scopus 로고
    • The endocytotic rate constant. A cellular parameter for quantitating receptor-mediated endocytosis
    • Wiley HS, Cunningham DD. 1982. The endocytotic rate constant. A cellular parameter for quantitating receptor-mediated endocytosis. J Biol Chem, 257:4222-9.
    • (1982) J Biol Chem , vol.257 , pp. 4222-4229
    • Wiley, H.S.1    Cunningham, D.D.2
  • 103
    • 0020026141 scopus 로고
    • Kinetic analysis of chemotactic peptide receptor modulation
    • Zigmond S, Sullivan S, Lauffenburger D. 1982. Kinetic analysis of chemotactic peptide receptor modulation. J Cell Biol, 92:34-43.
    • (1982) J Cell Biol , vol.92 , pp. 34-43
    • Zigmond, S.1    Sullivan, S.2    Lauffenburger, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.