Spermidinyl-CoA-based HAT inhibitors block DNA repair and provide cancer-specific chemo- and radiosensitization

Cell Cycle

Volumn 8, Issue 17, 2009, Pages 2779-2788

  Bandyopadhyay, Keya ^a   Banères, Jean Louis ^b   Martin, Aimée ^b   Blonski, Casimir ^c,e   Parello, Joseph ^d   Gjerset, Ruth A ^a  

^a SIDNEY KIMMEL CANCER CENTER   (United States)

^b UNIVERSITÉ DE MONTPELLIER   (France)

^c UPS)   (France)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITÉ PARIS SUD   (France)

Author keywords

Chemosensitization; DNA repair; HAT inhibitor; Histone acetylation; Radiosensitization

Indexed keywords

CAMPTOTHECIN; CISPLATIN; COENZYME A; FLUOROURACIL; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE INHIBITOR; HISTONE DEACETYLASE INHIBITOR; SPERMIDINE; THIOGLYCOLIC ACID; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CANCER CELL; CELL CYCLE S PHASE; CELL VIABILITY; CHEMOSENSITIZATION; CHROMATIN; DNA DAMAGE; DNA REPAIR; DNA SYNTHESIS; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; HUMAN; HUMAN CELL; IRRADIATION; RADIOSENSITIZATION;

EID: 69749114371     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.17.9416     Document Type: Article

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