Lipid-formulated bcg as an oral-bait vaccine for tuberculosis: Vaccine stability, efficacy, and palatability to brushtail possums (Trichosurus vulpecula) in New Zealand

Journal of Wildlife Diseases

Volumn 45, Issue 3, 2009, Pages 754-765

  Cross, Martin L ^a   Henderson, Ray J ^b   Lambeth, Matthew R ^a   Buddle, Bryce M ^c   Aldwell, Frank E ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b Pest Tech Ltd   (New Zealand)

^c AGRESEARCH GRASSLANDS   (New Zealand)

Author keywords

BCG; New zealand; Oral vaccine; Possum; Tuberculosis

Indexed keywords

ANIMALIA; BACILLI (CLASS); BOVINAE; MYCOBACTERIUM BOVIS; MYRRHIS ODORATA; PHALANGERIDAE; THEOBROMA CACAO; TRICHOSURUS; TRICHOSURUS VULPECULA;

BCG VACCINE; DRUG CARRIER; IMMUNOLOGICAL ADJUVANT; LIPID;

ANIMAL; ANIMAL DISEASE; ARTICLE; DISEASE CARRIER; IMMUNOLOGY; MYCOBACTERIUM BOVIS; NEW ZEALAND; ORAL DRUG ADMINISTRATION; TASTE; TREATMENT OUTCOME; TRICHOSURUS; TUBERCULOSIS;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; BCG VACCINE; DISEASE RESERVOIRS; DRUG CARRIERS; LIPIDS; MYCOBACTERIUM BOVIS; NEW ZEALAND; TASTE; TREATMENT OUTCOME; TRICHOSURUS; TUBERCULOSIS;

EID: 69749096600     PISSN: 00903558     EISSN: None     Source Type: Journal    
DOI: 10.7589/0090-3558-45.3.754     Document Type: Article

References (38)

1. ALDWELL, F. E., M. A. BAIRD, C. E. FITZPATRICK, A. D. MCLELLAN, M. L. CROSS, M. R. LAMBETH, AND G. S. BUCHAN. 2005. Oral vaccination of mice with lipid-encapsulated Mycobacterium bovis BCG: Anatomical sites of bacterial replication and immune activity. Immunology and Cell Biology 83: 549-553.
2. -, M. L. CROSS, C. E. FITZPATRICK, M. R.LAMBETH, G. W. DE LISLE, AND B. M. BUDDLE. 2006. Oral, delivery of lipid-encapsulated Mycobacterium bovis BCG extends survival, of the bacillus in vivo and induces a long-term, protective immune response against tuberculosis. Vaccine 24: 2071-2078.
3. -, D. L. KEEN, N. A. PARLANE, M. A. SKINNER, G. W. DE LISLE, AND B. M. BUDDLE. 2003a. Oral. vaccination with Mycobacterium bovis BCG in a lipid formulation induces resistance to pulmonary tuberculosis in brushtail possums. Vaccine 22: 70-76.
4. -, I. G. TUCKER, G. W. DE LISLE, AND B. M. BUDDLE. 2003b. Oral, delivery of Mycobacterium bovis BCG in a lipid formulation induces resistance to pulmonary tuberculosis in mice. Infection and Immunity 71: 101-108.
5. Anonymous. 2007. Animal Health Board Annual report for the year ending June 30th 2007. http://www.ahb.org.nz/NR/rdonlyres/79CB90CA-EBCE-46F7- BEB0-153E42860FB6/554/AHBAnnual.Report-PartAWeb.pdf. Accessed 3 May 2008.
6. BARLOW, N. D. 1991. Control of endemic bovine tuberculosis in New Zealand possum populations: Results of a simple model. Journal of Animal Ecology 28: 794-809.
7. BLACKWELL, B. F., T. W. SEAMANS, R. J. WHITE, Z. J. PATTON, R. M. BUSH, AND J. D. CEPEK, 2004. Exposure time of oral rabies vaccine baits relative to baiting density and raccoon population density. Journal, of Wildlife Diseases 40: 222-229.
8. BLOME, S., A. MEINDL-BÖHMER, W. LOEFFEN, B. THUER, AND V. MOENNIG. 2006. Assessment of classical swine fever diagnostics and vaccine performance. Revue Scientifique et Technique (International Office of Epizootics) 25: 1025-1038.
9. BUDDLE, B. M., F. E. ALDWELL, D. L. KEEN, N. A. PARLANE, K. L. HAMEL, AND G. W. DE LISLE. 2006. Oral vaccination of brushtail possums with BCG: Investigation, into factors that, may influence vaccine efficacy and determination, of duration of protection. New Zealand Veterinary Journal 54: 224-230.
10. CALEY, P., G. J. HICKLING, P. E. COWAN, AND D. U. PFEIFFER. 1999. Effects of sustained control of brushtail possums on levels of Mycobacterium bovis infection in cattle and brushtail possum populations from Hohotaka, New Zealand. New Zealand Veterinary Journal 47: 133-142.
11. CAMPBELL, T. A., S. J. LAPIDCE, AND D. B. LONG. 2006. Using baits to deliver pharmaceuticals to feral swine in southern Texas. Wildlife Society Bulletin 34: 1184-1189.
12. CLEAVELAND, S., T. MLENGEYA, R. R. KAZWALA, A. MICHEL, M. T. KAARE, S. L. JONES, E. EBLATE, G. M. SHIRIMA, AND C. PACKER. 2005. Tuberculosis in Tanzanian wildlife. Journal of Wildlife Dis-eases 41: 446-453.
13. -, D. J. SHAW, S. G. MFINANGA, G. SHIRIMA, R. R. KAZWALA, E. EBLATE, AND M. SHARP. 2007. Mycobacterium bovis in rural Tanzania: risk factors for infection in human and cattle populations. Tuberculosis 87: 30-43.
14. COLLINS, D. M., G. W. DE LISLE, F. E. ALDWELL, AND B. M. BUDDLE. 2007. A new attenuated Mycobacterium bovis vaccine protects brushtail possums (Trichosurus vulpecula) against experimental tuberculosis infection. Vaccine 25: 4659-4664.
15. CORNER, L. A., S. NORTON, B. M. BUDDLE, AND R. S. MORRIS. 2002. The efficacy of bacille CalmetteGuerin vaccine in wild brushtail possums (Trichosurus vulpecula). Research in Veterinary Science 73: 145-152.
16. CREEKMORE, T. E., T. E. ROCKE, AND J. A. HURLEY. 2002. A baiting system for delivery of an oral plague vaccine to black-tailed prairie clogs. Journal of Wildlife Diseases 38: 32-39.
17. CROSS, M. L., B. M. BUDDLE, AND F. E. ALDWELL. 2007a. The potential of oral vaccines for disease control in wildlife species. Veterinary Journal 174: 472-480.
18. -, M. R. LAMBETH, Y. COUGHLAN, AND F. E. ALDWELL. 2007b. Oral vaccination of mice with lipid-encapsulated Mycobacterium bovis BCG: Effect of reducing or eliminating BCG load on cell-mediated immunity. Vaccine 25: 1297-1303.
19. -, AND F. E. ALDWELL. 2008. Murine cytokine responses following multiple oral immunizations using lipid-formulated mycobacterial antigens. Immunology and Cell Biology 86: 214-217.
20. EFFORD, M. 2000. Possum density, population, structure and dynamics. In The brushtail possum: Biology, impact and management of an introduced marsupial, T. L. Montague (ed.). Manaaki Whenua Press, Lincoln, New Zealand, pp. 47-61.
21. GILLIES, C. A., M. R. LEACH, N. B. COAD, S. W. THEOBALD, J. CAMPBELL, T. HERBERT, P. J. GRAHAM, AND R. J. PIERCE. 2003. Six years of intensive pest mammal control, at Trounson Kauri Park, a Department of Conservation, "mainland island," June 1996-July 2002. New Zealand Journal of Zoology 30: 399-420.
22. HENDERSON, R. J. AND G. J. HICKLING. 1997. Possum behaviour as a factor in sublethal poisoning during control operations using cereal, baits. New Zealand Animal Health Board Research Report. http://tbfree.ahb.org.nz/Default. aspx?ta bid=255&xmid=406. Accessed 27 March 2009.
23. KADEN, V., C. RENNER, A. ROTHE, E. LANCE, A. HÄNEL, AND K. GOSSGER. 2003. Evaluation of the oral immunisation of wild boar against classical swine fever in Baden-Württemberg. Berliner und Münchener tierärztliche Wochenschrift 116: 362-367.
24. LAWSON, K. F., AND P. BACHMANN. 2001. Stability of attenuated live virus rabies vaccine in baits targeted to wild foxes under operational conditions. Canadian Veterinary Journal 42: 368-374.
25. LINHART, S. B., J. C. WLODKOWSKI, D. M. KAVANAUGH, L. MOTES-KREIMEYER, A. J. MONTONEY, R. B. CHIPMAN, D. SLATE, L. L. BIGLER, AND M. G. FEARNEYHOUOH, 2002. A new flavor-coated sachet bait for delivering oral rabies vaccine to raccoons and coyotes. Journal of Wildlife Diseases 38: 363-377.
26. LIVINGSTONE, P. G., T. J. RYAN, N. HANCOX, K. B. CREWS, M. A. J. BOSSON, AND G. J. E. KNOWLES. 2006. Regionalisation: A strategy for facilitating trade and assisting with bovine tuberculosis control. Veterinary Microbiology 112: 291-301. (Pubitemid 43182759)
27. MCMURRAY, D. N. 2001. Determinants of vaccineinduced resistance in animal models of pulmonary tuberculosis. Scandinavian Journal of Infectious Diseases 33: 175-178.
28. MORGAN, D., AND G. HICKLING. 2000. Techniques used for poisoning possums. In The brushtail possum: Biology, impact and management of an introduced marsupial, T. L. Montague (ed.). Manaaki Whenua Press, Lincoln, New Zealand, pp. 143-153.
29. MORGAN, D. R., L. INNES, C. M. FRAMPTON, AND A. D. WOOLHOUSE. 1995. Responses of captive and wild possums to lures used in poison baiting. New Zealand Journal of Zoology 22: 123-129.
30. O'BRIEN, D. J., S. M. SCHMITT, S. D. FITZGERALD, D. E. BERRY, AND G. J. HICKLING. 2006. Managing the wildlife reservoir of Mycobacterium bovis: The Michigan, USA, experience. Veterinary Microbiology 112: 13-23.
31. PHILLIPS, C. J., C. R. FOSTER, P. A. MORRIS, AND R. TEVERSON. 2003. The transmission of Mycobacterium bovis infection, to cattle. Research in Veterinary Science 74: 1-15.
32. ROBERTS, M. 1995. Tuberculosis control in possums: culling or vaccination? In Tuberculosis in wildlife and domestic animals, F. Griffin, and G. de Lisle (eds.). University of Otago Press, Dunedin, New Zealand, pp. 222-224.
33. ROSAITE, R. C., AND K. F. LAWSON. 2001. Acceptance of baits for delivery of oral rabies vaccine to raccoons. Journal of Wildlife Diseases 37: 730-739.
34. RUPPRECHT, C. E., C. A. HANLON, AND D. SLATE. 2004. Oral vaccination of wildlife against rabies: Opportunities and challenges in prevention and control. Developments in Biologicals 119: 173-184.
35. RYAN, T. J., P. G. LIVINGSTONE, D. S. RAMSEY, G. W. DELISLE, G. NUGENT, D. M. COLLINS, AND B. M. BUDDLE. 2006. Advances in understanding disease epidemiology and implications for control and eradication of tuberculosis in. livestock: The experience from New Zealand. Veterinary Microbiology 112: 211-219.
36. SKINNER, M. A., D. L. KEEN, N. A. PARLANE, G. YATES, AND B. M. BUDDLE. 2002. Increased protection against bovine tuberculosis in the brushtail possum (Trichosurus vulpecula) when. BCG is administered with killed Mycobacterium vaccae. Tuberculosis 82: 15-22.
37. TOMPKINS, D., D. RAMSEY, B. M. BUDDLE, F. E. ALDWELL, AND G. W. DE LISLE. 2007. Efficacy of an oral Tb vaccine on wild possum populations. New Zealand Animal Health Board Project no. R-10630, online report, http://tbfree.ahb.org. nz/Default.aspx?tabid=255&xmid=406. Accessed 27 March 2009.
38. WEDLOCK, D. N., F. E. ALDWELL, D. KEEN, M. A. SKINNER, AND B. M. BUDDLE. 2005. Oral vaccination of brushtail possums (Tricliosurus vulpecula) with BCG: Immune responses, persistence of BCG in lymphoid organs and excretion, in faeces. New Zealand Veterinary Journal 53: 301-306.