The folding pathway of onconase is directed by a conserved intermediate

Biochemistry

Volumn 48, Issue 35, 2009, Pages 8449-8457

  Schulenburg, Cindy ^a   Löw, Christian ^a,b   Weininger, Ulrich ^a   Mrestani Klaus, Carmen ^a   Hofmann, Hagen ^a,c   Balbach, Jochen ^a   Ulbrich Hofmann, Renate ^a   Arnold, Ulrich ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2D-NMR SPECTROSCOPY; AMINO ACID RESIDUES; AMINO ACID SEQUENCE; CIS-TO-TRANS ISOMERIZATION; CONSERVED RESIDUES; FOLDING BEHAVIOR; FOLDING MECHANISM; FOLDING PATHWAY; HIGH-RESOLUTION TECHNIQUES; HOMOLOGOUS PROTEINS; HYDROGEN/DEUTERIUM EXCHANGE; LEOPARD FROGS; MODEL PROTEINS; MODEL SYSTEM; NATIVE STATE; NMR SPECTROSCOPY; ONCONASE; PRIMARY STRUCTURES; RAPID MIXING; REFOLDING; RIBONUCLEASE A; RNASE A; SEQUENCE IDENTITY; STOPPED FLOW; STRUCTURAL ASSIGNMENTS; STRUCTURE FORMATIONS; TERTIARY STRUCTURES;

AMINATION; AMINES; AMINO ACIDS; ENZYMES; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; ISOMERIZATION; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANIC ACIDS; THERMODYNAMIC STABILITY;

PROTEIN FOLDING;

RANPIRNASE; RIBONUCLEASE A;

AMINO ACID SEQUENCE; ARTICLE; FLUORESCENCE SPECTROSCOPY; ISOMERIZATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; THERMODYNAMICS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CIRCULAR DICHROISM; DEUTERIUM; DISULFIDES; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN FOLDING; RIBONUCLEASE, PANCREATIC; RIBONUCLEASES; THERMODYNAMICS;

RANA PIPIENS;

EID: 69749094680     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900596j     Document Type: Article

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