Online measurement of hydrocortisone particles and improvement of the crystallization process

Chemical Engineering and Technology

Volumn 32, Issue 7, 2009, Pages 1073-1077

  Chen, Jianxin ^a   Yuan, Junsheng ^a   Ulrich, Joachim ^b   Wang, Jingkang ^c  

^a HEBEI UNIVERSITY OF TECHNOLOGY   (China)

^b MARTIN LUTHER UNIVERSITÄT HALLE WITTENBERG   (Germany)

^c TIANJIN UNIVERSITY   (China)

Author keywords

Crystallization; Online measurement; Particle size; Process control

Indexed keywords

CONTROL OF CRYSTALLIZATION; CRYSTAL PARTICLE SIZE; CRYSTAL QUALITIES; CRYSTALLIZATION PROCESS; FOCUSED BEAM REFLECTANCE MEASUREMENT; LASER DIFFRACTION METHOD; OFFLINE; ONLINE MEASUREMENT; ONLINE MONITORING; POLYVINYLCHLORIDE;

CAPILLARY FLOW; CRYSTALLIZATION; PROCESS CONTROL;

PARTICLE SIZE;

EID: 69649093361     PISSN: 09307516     EISSN: 15214125     Source Type: Journal    
DOI: 10.1002/ceat.200900017     Document Type: Article

References (16)

1. S. R. Tomme, C. F. Nostrum, M. Dijkstra, Eur. J. Pharm. Biopharm. 2008, 70, 522.
2. L. V. Allen, Clin. Ther. 2008, 30, 2102.
3. Representation of Results of Particle Size Analysis - Part 1: Graphical Representation, ISO 9276-1, International Standards Organization, Geneva 1998
4. U. Teipel, M. Sisler, in Proc. of the 16th Int. Conf. on Industrial Crystallization (Ed: J. Ulrich), VDI-Verlag, Düsseldorf 2005.
5. W. Yu, K. Erickson, Powder Technol. 2008, 185, 24.
6. A. Ruf, J. Worlischek, M. Mazzotti, Part. Part. Syst. Charact. 2000,17,167.
7. R. J. Farrell, Y. C. Tsai, AIChE J. 1995, 41, 2318.
8. N. Kail, H. Briesen, W. Marquardt, Powder Technol. 2008, 185,211.
9. FBRM Control Interface User's Manual, Version 6.0, Mettler Toledo Co., Columbus, OH 2004.
10. J. Worlitschek, M. Mazzoti, Part. Part. Syst. Charact. 2003, 20,12.
11. A. Abbas, D. Nobbs, J. A. Romagnoli, Meas. Sci. Technol. 2002,13,349.
12. J. W. Mullin, Crystallization, 4th ed., Butterworth-Heinemann, Oxford 2001.
13. A. D. Randolph, M. A. Larson, Theory of Particulate Processes, 2nd ed., Academic Press, New York 1988.
14. P. Barrett, B. Smith, Org. Process Res. Dev. 2005, 9, 348.
15. A. Warstat, J. Ulrich. Chem. Eng. Technol. 2006, 2,187.
16. J. Heinrich, J. Ulrich, 17th Int. Conf. on Industrial Crystallization, Maastricht, NL, September 2008.