General 4-week toxicity study with EMS in the rat

Toxicology Letters

Volumn 190, Issue 3, 2009, Pages 271-285

  Pfister, Thomas ^a   Eichinger Chapelon, Anne ^b  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b Harlan   (Switzerland)

Author keywords

Ethyl methanesulfonate; General toxicity; Hematology; Nelfinavir mesilate; Reproductive organ; Viracept

Indexed keywords

HEMOGLOBIN; MESYLIC ACID ETHYL ESTER;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BLOOD TOXICITY; BODY WEIGHT; BONE MARROW TOXICITY; CELL DAMAGE; CELL DEATH; CELL PROLIFERATION; CELL VACUOLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FOOD INTAKE; GERM CELL; HEALTH HAZARD; HEMATOLOGICAL PARAMETERS; HEMATOPOIESIS; HEMOGLOBIN BLOOD LEVEL; HEMOGLOBIN DETERMINATION; INFLAMMATION; INTOXICATION; LEUKOCYTE COUNT; LYMPH NODE; NONHUMAN; ORGAN SIZE; PANCREAS DISEASE; PRIORITY JOURNAL; RAT; REPRODUCTIVE TOXICITY; SPLEEN DISEASE; THYMUS ATROPHY; THYROID FOLLICLE CELL; TOXICOKINETICS;

ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CONTAMINATION; EATING; ETHYL METHANESULFONATE; FEMALE; GENITALIA; HEMATOLOGIC TESTS; HEMOGLOBINS; HIV PROTEASE INHIBITORS; MALE; MUTAGENS; NELFINAVIR; ORGAN SIZE; RATS; RATS, WISTAR; RISK ASSESSMENT; SPECIFIC PATHOGEN-FREE ORGANISMS; TOXICITY TESTS;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 69549152002     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.04.031     Document Type: Article

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